BRPI0408063A - métodos e composições envolvendo mda-7 - Google Patents

métodos e composições envolvendo mda-7

Info

Publication number
BRPI0408063A
BRPI0408063A BRPI0408063-7A BRPI0408063A BRPI0408063A BR PI0408063 A BRPI0408063 A BR PI0408063A BR PI0408063 A BRPI0408063 A BR PI0408063A BR PI0408063 A BRPI0408063 A BR PI0408063A
Authority
BR
Brazil
Prior art keywords
methods
mda
compositions
present
compositions involving
Prior art date
Application number
BRPI0408063-7A
Other languages
English (en)
Inventor
Sunil Chada
John B Mumm
Rajagopal Ramesh
Abner Mhashilkar
Raymond E Meyn
Elizabeth Grimm
Original Assignee
Univ Texas
Introgen Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas, Introgen Therapeutics Inc filed Critical Univ Texas
Publication of BRPI0408063A publication Critical patent/BRPI0408063A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Radiation-Therapy Devices (AREA)
  • Peptides Or Proteins (AREA)

Abstract

"MéTODOS E COMPOSIçõES ENVOLVENDO MDA7". A presente invenção refere-se a composições e métodos envolvendo MDA-7. Mais especificamente, a presente invenção é dirigida a composições diagnósticas, prognósticas e de tratamento terapêutico e métodos para tratamento de câncer e outros distúrbios relacionados com angiogenese (terapia anti-angiogenese). A presente invenção é também dirigida a métodos de purificação de MDA-7.
BRPI0408063-7A 2003-03-03 2004-03-02 métodos e composições envolvendo mda-7 BRPI0408063A (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US45225703P 2003-03-03 2003-03-03
US47452903P 2003-05-30 2003-05-30
US47615903P 2003-06-04 2003-06-04
US48686203P 2003-07-11 2003-07-11
US51528503P 2003-10-29 2003-10-29
US52850603P 2003-12-10 2003-12-10
PCT/US2004/006147 WO2004078124A2 (en) 2003-03-03 2004-03-02 Methods and compositions involving mda-7

Publications (1)

Publication Number Publication Date
BRPI0408063A true BRPI0408063A (pt) 2006-02-14

Family

ID=32966871

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0408063-7A BRPI0408063A (pt) 2003-03-03 2004-03-02 métodos e composições envolvendo mda-7

Country Status (9)

Country Link
US (1) US20060134801A1 (pt)
EP (1) EP1603943A2 (pt)
JP (1) JP2006523227A (pt)
KR (1) KR20060002793A (pt)
CN (2) CN1759122B (pt)
AU (1) AU2004218407A1 (pt)
BR (1) BRPI0408063A (pt)
CA (1) CA2518150C (pt)
WO (1) WO2004078124A2 (pt)

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WO2002057283A1 (en) * 2001-01-19 2002-07-25 Baylor College Of Medecine Methods and compositions in breast cancer diagnosis and therapeutics
CN100406567C (zh) * 2002-01-22 2008-07-30 生物材料公司 生物可降解聚合物的干燥方法
JP2005533000A (ja) * 2002-03-05 2005-11-04 ボード　オブ　リージェンツ，　ザ　ユニバーシティ　オブ　テキサス　システム Ｍｄａ−７に関与する免疫誘導を増強する方法
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CA2548220A1 (en) * 2003-12-01 2005-09-09 Introgen Therapeutics, Inc. Use of mda-7 to inhibit infection by pathogenic organisms
US20070281041A1 (en) * 2004-03-02 2007-12-06 Introgen Therapeutics, Inc. Compositions and Methods Involving MDA-7 for the Treatment of Cancer
CN101166539B (zh) * 2005-02-08 2012-01-04 得克萨斯大学体系董事会 用于治疗癌症的涉及mda-7的组合物和方法
WO2007092944A2 (en) * 2006-02-08 2007-08-16 Introgen Therapeutics, Inc. Compositions and methods involving gene therapy and proteasome modulation
TW200819540A (en) 2006-07-11 2008-05-01 Genelux Corp Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders
EP2426142A3 (en) * 2006-10-16 2012-06-13 Genelux Corporation Modified vaccinia virus strains for use in a diagnostic and therapeutic method
CA2693310C (en) * 2007-08-02 2018-11-27 Arresto Biosciences, Inc. Lox and loxl2 inhibitors, antibodies and uses thereof
WO2010080769A2 (en) 2009-01-06 2010-07-15 Arresto Biosciences, Inc. Chemotherapeutic methods and compositions
WO2011022670A1 (en) * 2009-08-21 2011-02-24 Arresto Biosciences, Inc In vivo screening assays
CN102711821A (zh) * 2009-08-21 2012-10-03 吉联亚生物科技有限公司 治疗方法和组合物
WO2011022709A1 (en) * 2009-08-21 2011-02-24 Arresto Biosciences, Inc In vitro screening assays
AU2010283997B2 (en) * 2009-08-21 2015-04-09 Gilead Biologics, Inc. Methods and compositions for treatment of pulmonary fibrotic disorders
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US8680246B2 (en) 2010-02-04 2014-03-25 Gilead Biologics, Inc. Antibodies that bind to lysyl oxidase-like 2 (LOXL2)
EP2708236A1 (en) * 2012-09-12 2014-03-19 Medizinische Universität Wien Tumor treatment
US9951114B2 (en) * 2013-06-04 2018-04-24 Virginia Commonwealth University Recombinant cancer therapeutic cytokine
KR102353589B1 (ko) * 2014-03-17 2022-01-19 에이전시 포 사이언스, 테크놀로지 앤드 리서치 핵 인자-κB 전위에 근거하여 화합물의 독성을 예측하는 방법
US11045436B2 (en) * 2015-06-30 2021-06-29 Shanghai Jiao Tong University Applications for sulindac in preparing anti-lung cancer products
US20200199681A1 (en) * 2016-11-14 2020-06-25 Virginia Commonweatlh University Mda-7 cancer therapies and methods of detecting biomolecules
US20180201662A1 (en) * 2016-11-30 2018-07-19 Industrial Technology Research Institute Peptide for promoting cell migration and/or skin wound healing, pharmaceutical composition containing the same, and application thereof
WO2019084401A1 (en) * 2017-10-27 2019-05-02 Virginia Commonwealth University COMPOSITIONS COMPRISING THE MDA-7 / IL-24 PROTEIN AND METHODS OF USE
CN109122581A (zh) * 2018-09-18 2019-01-04 南通市第二人民医院 Fra-1与XPA复合物在细胞周期调控中的应用

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Also Published As

Publication number Publication date
CA2518150C (en) 2015-08-11
CN1759122B (zh) 2012-06-13
HK1180218A1 (en) 2013-10-18
JP2006523227A (ja) 2006-10-12
AU2004218407A1 (en) 2004-09-16
KR20060002793A (ko) 2006-01-09
WO2004078124A2 (en) 2004-09-16
CA2518150A1 (en) 2004-09-16
EP1603943A2 (en) 2005-12-14
CN1759122A (zh) 2006-04-12
AU2004218407A2 (en) 2004-09-16
CN102836420A (zh) 2012-12-26
WO2004078124A3 (en) 2005-05-12
CN102836420B (zh) 2014-03-12
US20060134801A1 (en) 2006-06-22

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements