BRPI0408965B8 - método de coloração de uma amostra biológica fixa e uso de detergente - Google Patents

método de coloração de uma amostra biológica fixa e uso de detergente

Info

Publication number
BRPI0408965B8
BRPI0408965B8 BRPI0408965A BRPI0408965A BRPI0408965B8 BR PI0408965 B8 BRPI0408965 B8 BR PI0408965B8 BR PI0408965 A BRPI0408965 A BR PI0408965A BR PI0408965 A BRPI0408965 A BR PI0408965A BR PI0408965 B8 BRPI0408965 B8 BR PI0408965B8
Authority
BR
Brazil
Prior art keywords
biological sample
staining method
fixed biological
detergent use
pap
Prior art date
Application number
BRPI0408965A
Other languages
English (en)
Inventor
Lapen Daniel
Soule Norman
Lim Somthouk
Original Assignee
Cytyc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytyc Corp filed Critical Cytyc Corp
Publication of BRPI0408965A publication Critical patent/BRPI0408965A/pt
Publication of BRPI0408965B1 publication Critical patent/BRPI0408965B1/pt
Publication of BRPI0408965B8 publication Critical patent/BRPI0408965B8/pt

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

"processo de manchamento papanicolau". a presente invenção refere-se a um método para tratamento de uma amostra biológica com um processo de manchamento papanicolau. o método compreende incorporar um tratamento detergente ao processo de manchamento em quaisquer de várias etapas. o método foi visto reduzir, vantajosamente o número de artefatos produzidos durante o manchamento papanicolau. também se providencia uma amostra manchada por um tal processo.
BRPI0408965A 2003-03-31 2004-03-26 método de coloração de uma amostra biológica fixa e uso de detergente BRPI0408965B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/404,879 US7186522B2 (en) 2003-03-31 2003-03-31 Papanicolau staining process
PCT/US2004/009437 WO2004086945A2 (en) 2003-03-31 2004-03-26 Papanicolau staining process

Publications (3)

Publication Number Publication Date
BRPI0408965A BRPI0408965A (pt) 2006-04-04
BRPI0408965B1 BRPI0408965B1 (pt) 2016-05-31
BRPI0408965B8 true BRPI0408965B8 (pt) 2021-07-27

Family

ID=32990208

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0408965A BRPI0408965B8 (pt) 2003-03-31 2004-03-26 método de coloração de uma amostra biológica fixa e uso de detergente

Country Status (10)

Country Link
US (2) US7186522B2 (pt)
EP (1) EP1608392B1 (pt)
JP (1) JP4535396B2 (pt)
KR (1) KR101057872B1 (pt)
CN (1) CN1764469B (pt)
AT (1) ATE516810T1 (pt)
AU (1) AU2004226368B2 (pt)
BR (1) BRPI0408965B8 (pt)
CA (1) CA2519285C (pt)
WO (1) WO2004086945A2 (pt)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7186522B2 (en) * 2003-03-31 2007-03-06 Cytyc Corporation Papanicolau staining process
US8068988B2 (en) 2003-09-08 2011-11-29 Ventana Medical Systems, Inc. Method for automated processing of digital images of tissue micro-arrays (TMA)
WO2005027015A2 (en) * 2003-09-10 2005-03-24 Bioimagene, Inc. Method and system for quantitatively analyzing biological samples
EP2392908B1 (en) 2004-12-17 2019-08-21 Ventana Medical Systems, Inc. Methods for preparing a paraffin-embedded biological sample for staining.
JP4512765B2 (ja) * 2005-03-22 2010-07-28 独立行政法人理化学研究所 生体組織切片の前処理液及びこれを用いた生体組織中の核酸及び蛋白質の観測方法
US20070270627A1 (en) 2005-12-16 2007-11-22 North American Scientific Brachytherapy apparatus for asymmetrical body cavities
US8137256B2 (en) 2005-12-16 2012-03-20 Portola Medical, Inc. Brachytherapy apparatus
CA2835365A1 (en) * 2006-01-13 2007-07-26 Ventana Medical Systems, Inc. Biological sample processing composition and method
US7862497B2 (en) 2006-04-21 2011-01-04 Portola Medical, Inc. Brachytherapy device having seed tubes with individually-settable tissue spacings
US7972828B2 (en) * 2006-12-19 2011-07-05 Sigma-Aldrich Co. Stabilized compositions of thermostable DNA polymerase and anionic or zwitterionic detergent
WO2009048681A2 (en) 2007-08-06 2009-04-16 The Regents Of The University Of California Methods of tissue-based diagnosis
US9814422B2 (en) 2007-08-06 2017-11-14 The Regents Of The University Of California Compositions for solubilizing cells and/or tissue
CN103540156B (zh) * 2008-03-19 2016-09-07 爱科来株式会社 显色剂的稳定剂及其用途
WO2009148885A2 (en) * 2008-05-30 2009-12-10 Ventana Medical Systems, Inc. Hematoxylin staining method to address gradient staining
FR2931966A1 (fr) * 2008-05-30 2009-12-04 Novacyt Procede d'analyse cellulaire d'un prelevement au moyen d'une plaque d'analyse virtuelle
US11298113B2 (en) 2008-10-01 2022-04-12 Covidien Lp Device for needle biopsy with integrated needle protection
US9782565B2 (en) 2008-10-01 2017-10-10 Covidien Lp Endoscopic ultrasound-guided biliary access system
US8968210B2 (en) 2008-10-01 2015-03-03 Covidien LLP Device for needle biopsy with integrated needle protection
US9332973B2 (en) 2008-10-01 2016-05-10 Covidien Lp Needle biopsy device with exchangeable needle and integrated needle protection
US9186128B2 (en) 2008-10-01 2015-11-17 Covidien Lp Needle biopsy device
AU2009307661B2 (en) * 2008-10-21 2014-11-20 Thomas M. Donndelinger Methods and compositions for preventing artifacts in tissue samples
EP2449377B1 (fr) * 2009-06-30 2017-06-21 Assistance Publique - Hôpitaux de Paris Méthode de détection de cellules tumorales par signal de fluorescence
JP5801410B2 (ja) * 2010-11-10 2015-10-28 コンスティテューション・メディカル・インコーポレイテッドConstitution Medical, Inc. 検査用に生物試料を準備するための自動化されたシステムおよび方法
CN102559855B (zh) * 2010-12-10 2014-11-12 温州安得森生物科技有限公司 曙红及其衍生物在琼脂糖凝胶上dna负染检测中的应用
EP4086605B1 (en) * 2011-06-17 2025-06-11 Roche Diagnostics Hematology, Inc. Solution and method for histoprocessing of biological samples
ES2827785T3 (es) 2012-01-26 2021-05-24 Leica Biosystems Richmond Inc Kit para tinción con hematoxilina y eosina
MX369625B (es) * 2012-05-16 2019-11-14 Univ California Composiciones para solubilizar celulas y/o tejido.
CN102876081B (zh) * 2012-09-24 2014-05-14 广州鸿琪光学仪器科技有限公司 苏木素染色液以及含苏木素染色液的巴氏染色试剂盒
EP2980585B1 (en) * 2013-03-29 2019-11-20 Mie University Vital stain
CN103571909A (zh) * 2013-10-24 2014-02-12 温州市康泰生物科技有限公司 巴氏染色液及其使用方法
CN104744967B (zh) * 2013-12-31 2018-01-02 江苏省原子医学研究所 一种伊红染色液及其含伊红染色液的he染色液
CN103694732A (zh) * 2013-12-31 2014-04-02 江苏省原子医学研究所 一种苏木素染色液及其含苏木素染色液的he染色液
CN103725040B (zh) * 2013-12-31 2016-03-23 江苏省原子医学研究所 一种苏木素伊红染色液及其制备方法
US11364308B2 (en) 2016-05-13 2022-06-21 4D Molecular Therapeutics Inc. Adeno-associated virus variant capsids and methods of use thereof
US11022528B2 (en) 2017-04-21 2021-06-01 Korea Research Institute Of Chemical Technology Composition for biological tissue transparency and method for biological tissue transparency using same
CN108195653A (zh) * 2017-09-16 2018-06-22 南京福怡科技发展股份有限公司 一种复染染色试剂盒及制备和应用
RU2770922C2 (ru) 2017-09-20 2022-04-25 4Д Молекьюлар Терапьютикс Инк. Капсиды вариантов аденоассоциированных вирусов и методы их применения
KR102200618B1 (ko) 2018-01-12 2021-01-08 재단법인대구경북과학기술원 설포베타인계 쯔비터이온성 계면활성제를 포함하는 생물학적 분자의 조직침투용 조성물 및 이의 용도
KR20190043886A (ko) 2017-10-19 2019-04-29 재단법인대구경북과학기술원 설포베타인계 쯔비터이온성 계면활성제를 유효성분으로 포함하는 생물학적 시료의 면역화학염색용 조성물 및 이를 이용한 면역화학염색 방법
CN111770999A (zh) 2017-11-27 2020-10-13 4D分子治疗有限公司 腺相关病毒变体衣壳和用于抑制血管生成的应用
CN108195715B (zh) * 2017-12-15 2020-12-15 浙江海洋大学 一种纺锤水蚤类浮游动物密度检测方法
CN109406246A (zh) * 2018-10-25 2019-03-01 潍坊市康华生物技术有限公司 一种精子形态学快速染色试剂及其染色方法
US20220154211A1 (en) 2019-02-25 2022-05-19 Novartis Ag Compositions and methods to treat bietti crystalline dystrophy
SG11202108044YA (en) 2019-02-25 2021-09-29 Novartis Ag Compositions and methods to treat bietti crystalline dystrophy
CN115141876B (zh) * 2022-08-04 2025-08-15 华中农业大学 用于动物组织的裂解液及其在CUT&Tag中的使用方法
CN118329579B (zh) * 2024-06-13 2024-08-27 山东仕达思生物产业有限公司 一种采用革兰氏和巴氏染色方法检测滴虫用试剂

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5023187A (en) * 1985-09-13 1991-06-11 Fisher Scientific Company Method and device for accelerated treatment of thin sample on surface
JPS6453165A (en) * 1987-08-24 1989-03-01 Shiseido Co Ltd Preparation of cutaneous cell sample
JP3039594B2 (ja) * 1993-10-08 2000-05-08 株式会社日立製作所 染色試薬およびその使用方法
ATE365921T1 (de) * 1996-09-19 2007-07-15 Diagnocure Inc Immunologische zusammensetzung zum nachweis von blasenkrebs und verfahren zu ihrer verwendung
CA2335747A1 (en) * 1998-06-30 2000-01-06 Lamina, Inc. Cytological and histological fixative composition and methods of use
US6143512A (en) * 1998-08-17 2000-11-07 Markovic; Nenad Cap-pap test
AU766614B2 (en) * 1998-09-03 2003-10-23 Ventana Medical Systems, Inc. Removal of embedding media from biological samples and cell conditioning on automated staining instruments
JP2000116396A (ja) * 1998-10-16 2000-04-25 Idemitsu Kosan Co Ltd 微生物の染色方法と染色用組成物および染色用組成物の保存方法
JP2000258318A (ja) * 1999-03-09 2000-09-22 Muto Kagaku Kk 溶媒置換用組成物及びこれを用いた標本作成方法
EP1218547A4 (en) * 1999-10-15 2005-04-20 Ventana Med Syst Inc METHOD OF IN-SITU DETECTION OF INDIVIDUAL GENOCOPIES
US7186522B2 (en) * 2003-03-31 2007-03-06 Cytyc Corporation Papanicolau staining process

Also Published As

Publication number Publication date
WO2004086945A2 (en) 2004-10-14
EP1608392A4 (en) 2007-09-05
CA2519285A1 (en) 2004-10-14
WO2004086945A3 (en) 2005-05-26
KR20050118219A (ko) 2005-12-15
BRPI0408965A (pt) 2006-04-04
US20070003998A1 (en) 2007-01-04
BRPI0408965B1 (pt) 2016-05-31
CN1764469B (zh) 2010-07-28
EP1608392B1 (en) 2011-07-20
JP2006522337A (ja) 2006-09-28
JP4535396B2 (ja) 2010-09-01
EP1608392A2 (en) 2005-12-28
US20040191854A1 (en) 2004-09-30
US7186522B2 (en) 2007-03-06
HK1078280A1 (en) 2006-03-10
CA2519285C (en) 2013-05-21
KR101057872B1 (ko) 2011-08-19
CN1764469A (zh) 2006-04-26
AU2004226368A1 (en) 2004-10-14
AU2004226368B2 (en) 2009-03-26
ATE516810T1 (de) 2011-08-15

Similar Documents

Publication Publication Date Title
BRPI0408965B8 (pt) método de coloração de uma amostra biológica fixa e uso de detergente
BR9913406A (pt) Processo de tratamento de infecção causada por pelo menos um vìrus da famìlia flaviviridae e de doença associada com a citada infecção em um hospedeiro vivo possuindo a citada infecção
ATE239448T1 (de) Verfahren zur herstellung von wässrigen formulierungen für ophthalmische verwendung
BR0204980B1 (pt) Composições cosméticas que contêm pelo menos um silicone aminado e um agente espessante, uso de uma composição, uso de pelo menos um silicone aminado e processo de tratamento das matérias queratínicas
BRPI0214119B8 (pt) vírus adenoassociado recombinante, método de geração do referido vírus e composição compreendendo o referido vírus
IL159898A0 (en) Method for treating pulmonary disease states in mammals by altering indigenous in vivo levels of nitric oxide
DE60328421D1 (de) Verfahren zur herstellung von super-hydrophoben oberflächen, daraus hergestellte oberflächen und deren verwendung
DE502005002453D1 (de) Verfahren zur restrukturierung keratinischer fasern
BRPI0411471A (pt) método para produzir um não-trançado fibroso e não-trançado fibroso
PT1075284E (pt) Uso de um corante vital para facilitar as intervencoes cirurgicas em cirurgia vitreo-retiniana
BR0201170A (pt) Processo de deformação permanente das fibras queratìnicas que compreende silicones aminados, kit para deformação permanente das fibras queratìnicas e uso de uma composição cosmética
EP1834166A4 (en) APPARATUS FOR EXECUTING OPERATING PROCESSES OF OBJECT-HOLDER BLADES WITH TISSUE SPECIMENS
AR037274A1 (es) Un procedimiento de deformacion permanente de las fibras queratinicas, particularmente de los cabellos, un kit para dicha deformacion permanente de las fibras queratinicas y utilizacion de una composicion cosmetica de pre-tratamiento y/o de post-tratamiento
BR0205621A (pt) Composição para a tintura de oxidação das fibras queratìnicas, composição pronta para o uso para a tintura de oxidação das fibras queratìnicas, processos de tintura das fibras queratìnicas e dispositivos com vários compartimentos ou 'kit' para a tintura das fibras queratìnicas
DE60205528D1 (de) Verfahren zur Herstellung von optisch-aktiven Alkoholen
DE50101601D1 (de) Verfahren zur herstellung eines brillenglases
BRPI0410512A (pt) processo que compreende o contato de po3g e composição que compreende (i) po3g
AU2002366863A1 (en) Treatment compartment for treating histological samples
ATE493067T1 (de) Verfahren zur beobachtung von biologischem gewebe,insbesondere menschlicher haut
BRPI0411813A (pt) processo para purificação de um fluido lipofìlico por meio da modificação dos contaminantes
BR0104082A (pt) Processo de tratamento conveniente para a deformação e/ou conformação, e isto de modo permanente, dos materiais queratìnicos e, particulamente, dos cabelos, composição cosmética redutora, e kit para tratamento
WO2004087067A3 (en) Treatment of aspergillus infections with thymosin alpha 1
EP1469483A3 (en) Sample for manipulation by an optical tweezers, and a method and device to generate optically induced forces
MXPA03011253A (es) Composicion de tinte por oxidacion para fibras queratinas, que comprende alcohol graso, colorante de oxidacion, polimero asociativo y sulfato de alquilo con 14 a 30 atomos de carbono.
ATE297211T1 (de) Verfahren und zusammensetzung zur behandlung von adenovirale augeninfektionen

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]

Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI.

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 31/05/2016, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 26/03/2004, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 21A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2822 DE 04-02-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.