BRPI0408978B8 - processos para regenerar uma fase estacionária cromatográfica - Google Patents

processos para regenerar uma fase estacionária cromatográfica

Info

Publication number
BRPI0408978B8
BRPI0408978B8 BRPI0408978A BRPI0408978A BRPI0408978B8 BR PI0408978 B8 BRPI0408978 B8 BR PI0408978B8 BR PI0408978 A BRPI0408978 A BR PI0408978A BR PI0408978 A BRPI0408978 A BR PI0408978A BR PI0408978 B8 BRPI0408978 B8 BR PI0408978B8
Authority
BR
Brazil
Prior art keywords
stationary phase
regenerating
processes
chromatographic stationary
chromatographic
Prior art date
Application number
BRPI0408978A
Other languages
English (en)
Inventor
Schroder Rasmussen Eigil
Schou Ole
Larsen Per
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36118397&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0408978(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Priority claimed from PCT/DK2004/000234 external-priority patent/WO2004089504A1/en
Publication of BRPI0408978A publication Critical patent/BRPI0408978A/pt
Publication of BRPI0408978B1 publication Critical patent/BRPI0408978B1/pt
Publication of BRPI0408978B8 publication Critical patent/BRPI0408978B8/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
    • B01D15/203—Equilibration or regeneration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/283—Porous sorbents based on silica
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/285—Porous sorbents based on polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/34—Regenerating or reactivating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/34—Regenerating or reactivating
    • B01J20/3425—Regenerating or reactivating of sorbents or filter aids comprising organic materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/34—Regenerating or reactivating
    • B01J20/345—Regenerating or reactivating using a particular desorbing compound or mixture
    • B01J20/3475—Regenerating or reactivating using a particular desorbing compound or mixture in the liquid phase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/34—Regenerating or reactivating
    • B01J20/3433—Regenerating or reactivating of sorbents or filter aids other than those covered by B01J20/3408 - B01J20/3425

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"processos para regenerar uma fase estacionária cromatográfica e para produzir um polipeptídeo terapêutico ou um precursor do mesmo, uso do mesmo, fase estacionária cromatográfica, produto de polipeptídeo, equipamento cromatográfico automatizado, e, composição farmacêutica". processo para regenerar fases estacionárias cromatográficas.
BRPI0408978A 2003-04-08 2004-04-02 processos para regenerar uma fase estacionária cromatográfica BRPI0408978B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200300536 2003-04-08
DKPA200300536 2003-04-08
DKPA200400098 2004-01-26
DKPA200400098 2004-01-26
PCT/DK2004/000234 WO2004089504A1 (en) 2003-04-08 2004-04-02 Regeneration of chromatographic stationary phases

Publications (3)

Publication Number Publication Date
BRPI0408978A BRPI0408978A (pt) 2006-04-04
BRPI0408978B1 BRPI0408978B1 (pt) 2018-05-15
BRPI0408978B8 true BRPI0408978B8 (pt) 2021-07-27

Family

ID=36118397

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0408978A BRPI0408978B8 (pt) 2003-04-08 2004-04-02 processos para regenerar uma fase estacionária cromatográfica

Country Status (4)

Country Link
US (2) US20060102561A1 (pt)
KR (1) KR101198346B1 (pt)
CN (1) CN1771080B (pt)
BR (1) BRPI0408978B8 (pt)

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WO2010066676A1 (en) * 2008-12-09 2010-06-17 Upfront Chromatography A/S Method of removal of unbound, entrained and/or non-specifically adsorbed material from an affinity chromatography column
EP2446256B1 (en) * 2009-06-24 2015-02-25 F.Hoffmann-La Roche Ag Characterization of reusable chromatography equipment
CA2907454C (en) 2013-03-21 2021-05-04 Sanofi-Aventis Deutschland Gmbh Synthesis of hydantoin containing peptide products
US10450343B2 (en) 2013-03-21 2019-10-22 Sanofi-Aventis Deutschland Gmbh Synthesis of cyclic imide containing peptide products
US20150093800A1 (en) * 2013-09-05 2015-04-02 Genentech, Inc. Method for chromatography reuse
CN105424839A (zh) * 2015-12-15 2016-03-23 袁泳 高效液相色谱仪中反相填料柱的再生方法
CN105964606B (zh) * 2016-04-22 2018-07-10 内蒙古蒙牛乳业（集团）股份有限公司 延长色谱柱使用寿命的清洗方法
CN109011698B (zh) * 2018-08-25 2020-12-01 江苏曼氏生物科技股份有限公司 一种硅胶填料分离柱在线清洗及储存方法
CN112933660A (zh) * 2020-09-11 2021-06-11 石家庄新奥环保科技有限公司 一种离子色谱保护柱再生方法
CN112843789A (zh) * 2020-12-29 2021-05-28 上海赛梵科分离技术有限公司 大麻二酚纯化中色谱填料和层析介质的再生方法
AU2022216492A1 (en) * 2021-02-02 2023-07-27 Biocon Biologics Limited A process for the regeneration of silica based reverse phase chromatography material
BR112023023046A2 (pt) * 2021-05-07 2024-01-23 Genzyme Corp Composição e métodos de higienização

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US4164481A (en) * 1978-01-27 1979-08-14 The Dow Chemical Company Process of regenerating a noble metal catalyst used in the reduction of organic nitro compounds
SU1270689A1 (ru) 1984-12-17 1986-11-15 Предприятие П/Я В-8644 Способ регенерации хроматографической колонки
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JPH03505334A (ja) 1989-04-11 1991-11-21 イミユノバイオロジー・リサーチ・インスチチユート・インコーポレーテツド 凍結乾燥されたペプチド製剤
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UA65549C2 (uk) * 1996-11-05 2004-04-15 Елі Ліллі Енд Компані Спосіб регулювання ожиріння шляхом периферійного введення аналогів та похідних glp-1 (варіанти) та фармацевтична композиція
DE19652713C2 (de) * 1996-12-18 2001-11-22 Aventis Pharma Gmbh Verfahren zur Reinigung von Insulin und Insulinderivaten durch Chromatographie an stark saurem Kationenaustauscher
JPH10221323A (ja) * 1997-02-10 1998-08-21 Teijin Ltd 吸着カラムの連続使用方法及び装置
EP0971790B1 (en) * 1997-03-31 2005-06-01 Battelle Memorial Institute Method for ammonia removal from waste streams
EP1061946B1 (en) 1998-02-27 2004-04-28 Novo Nordisk A/S Glp-1 derivatives with helix-content exceeding 25 %, forming partially structured micellar-like aggregates
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DE69928006T2 (de) 1998-12-22 2006-07-13 Eli Lilly And Co., Indianapolis Lagerstabile flüssige zusammensetzungen von glucagon-ähnlichem peptid-1
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Also Published As

Publication number Publication date
KR101198346B1 (ko) 2012-11-06
US20060102561A1 (en) 2006-05-18
CN1771080A (zh) 2006-05-10
BRPI0408978B1 (pt) 2018-05-15
BRPI0408978A (pt) 2006-04-04
KR20060015496A (ko) 2006-02-17
US9364772B2 (en) 2016-06-14
CN1771080B (zh) 2010-12-15
US20080312131A1 (en) 2008-12-18

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B12B Appeal against refusal [chapter 12.2 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B16C Correction of notification of the grant [chapter 16.3 patent gazette]

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Free format text: INPI NO 52402.012649/2021-87 ORIGEM: 22A VARA FEDERAL CIVEL DA SJDF (TRF1) PROCESSO NO: 1087272-97.2021.4.01.3400 ACAO DE PROCEDIMENTO COMUM AUTOR: NOVO NORDISK A/S E NOVO NORDISK FARMACEUTICA DO BRASIL LTDA. REU(S): INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL ? INPI

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