BRPI0409049A - métodos de preparação de um composto, composição e composição cristalina - Google Patents

métodos de preparação de um composto, composição e composição cristalina

Info

Publication number
BRPI0409049A
BRPI0409049A BRPI0409049-7A BRPI0409049A BRPI0409049A BR PI0409049 A BRPI0409049 A BR PI0409049A BR PI0409049 A BRPI0409049 A BR PI0409049A BR PI0409049 A BRPI0409049 A BR PI0409049A
Authority
BR
Brazil
Prior art keywords
formula
composition
compound
preparing
methods
Prior art date
Application number
BRPI0409049-7A
Other languages
English (en)
Inventor
Gary David Annis
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of BRPI0409049A publication Critical patent/BRPI0409049A/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
    • C09B67/006—Preparation of organic pigments

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agronomy & Crop Science (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"MéTODOS DE PREPARAçãO DE UM COMPOSTO, COMPOSIçãO E COMPOSIçãO CRISTALINA". é descrito um método de preparação de um composto 5-oxo-3-pirazolidinocarboxilato 2-substituído da Fórmula I. O método compreende o contato de um derivado de ácido succínico da fórmula R¬ 1¬OC(O)C(H)(X)C(R¬ 2a¬)(R¬ 2b¬)C(O)Y (ou seja, Fórmula II), em que X e Y são grupos residuais e L, R¬ 1¬, R¬ 2a¬ e R¬ 2b¬ são conforme definido no relatório descritivo, com uma hidrazina substituída da fórmula LNHNH~ 2~ (ou seja, Fórmula III) na presença de um extrator de ácidos adequado e solvente. Também é descrita a preparação de compostos da Fórmula IV em que X¬ 1¬, R¬ 6¬, R¬ 7¬, R¬ 8¬, R¬ 8b¬, R¬ 9¬ e n são conforme definido no relatório descritivo. Também é descrita uma composição que compreende em base em peso cerca de 20 a 99% do composto da Fórmula II, em que R¬ 1¬, R¬ 2a¬, R¬ 2b¬, R¬ 3¬, R¬ 4¬ e R¬ 5¬ São conforme definido no relatório descritivo; X é CI, Br ou I; e Y é F, CI, Br ou I, desde que, quando R¬ 2a¬ e R¬ 2b¬ forem H cada um e X e Y forem CI cada um, R¬ 1¬ seja diferente de benzila e, quando R¬ 2a¬, e R¬ 2b¬ forem fenila cada um e X e Y forem CI cada um, R¬ 1¬ é diferente de metila ou etila. Também é descrita uma composição cristalina que compreende pelo menos cerca de 90% em peso do composto da fórmula R¬ 1¬OC(O)C(H)(X)C(R¬ 2a¬)(R¬ 2b¬)CO~ 2~H (ou seja, Fórmula VI) em que R¬ 2a¬ e R¬ 2b¬ são H cada um, X é Br e R¬ 1¬ é metila.
BRPI0409049-7A 2003-03-26 2004-03-25 métodos de preparação de um composto, composição e composição cristalina BRPI0409049A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45756103P 2003-03-26 2003-03-26
PCT/US2004/009188 WO2004087689A1 (en) 2003-03-26 2004-03-25 Preparation and use of 2-substituted-5-oxo-3- pyrazolidinecarboxylates

Publications (1)

Publication Number Publication Date
BRPI0409049A true BRPI0409049A (pt) 2006-03-28

Family

ID=33131691

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0409049-7A BRPI0409049A (pt) 2003-03-26 2004-03-25 métodos de preparação de um composto, composição e composição cristalina

Country Status (16)

Country Link
US (2) US7442799B2 (pt)
EP (1) EP1606276B1 (pt)
JP (1) JP4750019B2 (pt)
KR (1) KR101208748B1 (pt)
CN (1) CN100522958C (pt)
AT (1) ATE340791T1 (pt)
AU (1) AU2004225981A1 (pt)
BR (1) BRPI0409049A (pt)
DE (1) DE602004002579T2 (pt)
DK (1) DK1606276T3 (pt)
ES (1) ES2274477T3 (pt)
IL (1) IL169998A (pt)
PL (1) PL1606276T3 (pt)
TW (1) TWI367882B (pt)
WO (1) WO2004087689A1 (pt)
ZA (1) ZA200506096B (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1599463B1 (en) 2003-01-28 2013-06-05 E.I. Du Pont De Nemours And Company Cyano anthranilamide insecticides
KR20060008336A (ko) 2003-06-12 2006-01-26 이 아이 듀폰 디 네모아 앤드 캄파니 융합된 옥사지논 제조 방법
JP5215669B2 (ja) * 2004-11-18 2013-06-19 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー アントラニルアミド殺虫剤
AU2006283181A1 (en) * 2005-08-24 2007-03-01 E. I. Du Pont De Nemours And Company Anthranilamides for controlling invertebrate pests
TWI415827B (zh) 2006-12-21 2013-11-21 Du Pont 製備２-胺基-５-氰基苯甲酸衍生物之方法
JP5495618B2 (ja) * 2009-05-21 2014-05-21 国立大学法人 名古屋工業大学 光学活性トリフルオロメチル基含有化合物、その製造方法並びにそれを用いたトリフルオロメチル基含有光学活性アミン類の製造方法
MX2013008560A (es) 2011-01-28 2013-08-21 Du Pont Metodo para preparar derivados de 2-aminobenzamida.
EP2928471B1 (en) 2012-12-06 2020-10-14 Celgene Quanticel Research, Inc. Histone demethylase inhibitors
CN106928183B (zh) * 2015-12-29 2019-09-24 沈阳中化农药化工研发有限公司 吡啶基吡唑烷酮羧酸类化合物的制备方法
CN106831705B (zh) * 2016-12-28 2021-02-19 江苏扬农化工集团有限公司 一种吡啶基吡唑烷酮羧酸酯类化合物的合成方法
CN109053726A (zh) * 2018-09-14 2018-12-21 烟台万润药业有限公司 一种唑吡坦酸的制备方法
BR112022003171A2 (pt) * 2019-08-21 2022-05-17 Gharda Chemicals Ltd Processo para a síntese de compostos de pirazolidinona
CN110483480A (zh) * 2019-09-11 2019-11-22 江苏优普生物化学科技股份有限公司 2-(3-氯吡啶-2-基)-5-羟基-3-吡唑烷甲酸乙酯的合成方法
CN111440144A (zh) * 2020-03-06 2020-07-24 山东华科化工有限公司 一种微通道工业化生产溴代吡唑烷酸的方法
CN111620850B (zh) * 2020-05-27 2021-06-29 江苏七洲绿色化工股份有限公司 一种1-(3-氯吡啶-2-基)-3-溴-1h-吡唑-5-甲酸酯的制备方法
US11529599B1 (en) 2021-12-13 2022-12-20 Cana Technology, Inc. Electromechanical valve sequencing for fluid mixture dispensing devices
TW202342443A (zh) 2022-01-31 2023-11-01 美商富曼西公司 用於製備３－溴－１－（３－氯吡啶－２－基）－４，５－二氫－１ｈ－吡唑－５－甲酸乙酯之方法
TW202409000A (zh) 2022-08-29 2024-03-01 美商富曼西公司 用於製備３－鹵代－４，５－二氫－１ｈ－吡唑之高效新方法
TW202543493A (zh) 2024-03-06 2025-11-16 美商富曼西公司 ２－胺基苯甲醯胺衍生物的金屬催化合成

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL121416C (pt) * 1961-05-31
JPH01305071A (ja) 1988-06-03 1989-12-08 Nippon Oil Co Ltd オキサゾロン誘導体の製造方法
US5962523A (en) 1996-10-25 1999-10-05 Discovery Laboratories, Inc. Methods of using butyric acid derivatives to protect against hair loss
ATE346838T1 (de) 1999-05-18 2006-12-15 Sigma Tau Ind Farmaceuti Verfahren zur herstellung von r-(-)-carnitin aus s-(-)-chlorbernsteinsäure oder aus einem ihrer derivate
AR036872A1 (es) * 2001-08-13 2004-10-13 Du Pont Compuesto de antranilamida, composicion que lo comprende y metodo para controlar una plaga de invertebrados
JP4448327B2 (ja) * 2001-08-13 2010-04-07 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 新規置換１ｈ−ジヒドロピラゾール、それらの製造および使用
TWI356822B (en) * 2001-08-13 2012-01-21 Du Pont Novel substituted dihydro 3-halo-1h-pyrazole-5-car
TWI343376B (en) * 2002-07-31 2011-06-11 Du Pont Method for preparing 3-halo-4, 5-dihydro-1h-pyrazoles

Also Published As

Publication number Publication date
US20070021468A1 (en) 2007-01-25
CN1764658A (zh) 2006-04-26
US7442799B2 (en) 2008-10-28
DK1606276T3 (da) 2007-02-05
ES2274477T3 (es) 2007-05-16
DE602004002579D1 (de) 2006-11-09
KR20050114693A (ko) 2005-12-06
KR101208748B1 (ko) 2012-12-05
TW200504050A (en) 2005-02-01
WO2004087689A1 (en) 2004-10-14
JP4750019B2 (ja) 2011-08-17
EP1606276B1 (en) 2006-09-27
DE602004002579T2 (de) 2007-06-14
AU2004225981A1 (en) 2004-10-14
EP1606276A1 (en) 2005-12-21
IL169998A (en) 2011-07-31
TWI367882B (en) 2012-07-11
ZA200506096B (en) 2006-10-25
CN100522958C (zh) 2009-08-05
US20090036686A1 (en) 2009-02-05
US7834186B2 (en) 2010-11-16
PL1606276T3 (pl) 2007-01-31
JP2006521393A (ja) 2006-09-21
ATE340791T1 (de) 2006-10-15

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]

Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI.

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 12A ANUIDADE.

B11D Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time