BRPI0409187A - composição farmacêutica contendo um imunossupressor para uso no tratamento de doenças de pele - Google Patents

composição farmacêutica contendo um imunossupressor para uso no tratamento de doenças de pele

Info

Publication number
BRPI0409187A
BRPI0409187A BRPI0409187-6A BRPI0409187A BRPI0409187A BR PI0409187 A BRPI0409187 A BR PI0409187A BR PI0409187 A BRPI0409187 A BR PI0409187A BR PI0409187 A BRPI0409187 A BR PI0409187A
Authority
BR
Brazil
Prior art keywords
treatment
immunosuppressant
pharmaceutical composition
composition containing
skin diseases
Prior art date
Application number
BRPI0409187-6A
Other languages
English (en)
Inventor
Stefan Hirsch
Friedrich Karl Mayer
Carle Paul
Nabila Sekkat
Carl-Martin Weiss
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI0409187A publication Critical patent/BRPI0409187A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"COMPOSIçãO FARMACêUTICA CONTENDO UM IMUNOSSUPRESSOR PARA USO NO TRATAMENTO DE DOENçAS DE PELE". São fornecidas combinações sinérgicas de um imunomodulador ou imunossupressor de células T macrolídeo como 33-epicioro-33-desoxiascomicina e um emoliente como dimeticona, glicerol ou isoestearato de isoestearila, que são úteis, em particular, no tratamento de doenças dermatológicas ou de mucosas como pele seca ou dermatite atópica ou de contato.
BRPI0409187-6A 2003-04-04 2004-04-02 composição farmacêutica contendo um imunossupressor para uso no tratamento de doenças de pele BRPI0409187A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0307866.4A GB0307866D0 (en) 2003-04-04 2003-04-04 Pharmaceutical composition
PCT/EP2004/003513 WO2004087141A1 (en) 2003-04-04 2004-04-02 Pharmaceutical composition comprising an immunosuppressant for use in the treatment of skin diseases

Publications (1)

Publication Number Publication Date
BRPI0409187A true BRPI0409187A (pt) 2006-04-11

Family

ID=9956229

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0409187-6A BRPI0409187A (pt) 2003-04-04 2004-04-02 composição farmacêutica contendo um imunossupressor para uso no tratamento de doenças de pele

Country Status (13)

Country Link
US (1) US20070276004A1 (pt)
EP (1) EP1613314A1 (pt)
JP (1) JP2006522059A (pt)
CN (1) CN1767826A (pt)
AU (1) AU2004226821A1 (pt)
BR (1) BRPI0409187A (pt)
CA (1) CA2521250A1 (pt)
GB (1) GB0307866D0 (pt)
IS (1) IS8105A (pt)
MX (2) MXPA05010708A (pt)
NO (1) NO20055136L (pt)
RS (1) RS20050739A (pt)
WO (1) WO2004087141A1 (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0506139D0 (en) * 2005-03-24 2005-05-04 Transphase Ltd A transdermal topical composition and its uses
US9168383B2 (en) 2005-10-14 2015-10-27 Pacesetter, Inc. Leadless cardiac pacemaker with conducted communication
US8010209B2 (en) 2005-10-14 2011-08-30 Nanostim, Inc. Delivery system for implantable biostimulator
US10265265B2 (en) 2007-03-15 2019-04-23 Drug Delivery Solutions Limited Topical composition
EP2016935A1 (en) * 2007-07-09 2009-01-21 Intendis GmbH Pharmaceutical composition for topical application of poorly soluble compounds
US8527068B2 (en) 2009-02-02 2013-09-03 Nanostim, Inc. Leadless cardiac pacemaker with secondary fixation capability
US9060692B2 (en) 2010-10-12 2015-06-23 Pacesetter, Inc. Temperature sensor for a leadless cardiac pacemaker
EP2627403A4 (en) 2010-10-12 2014-03-26 Nanostim Inc Temperature sensor for a leadless cardiac pacemaker
US9020611B2 (en) 2010-10-13 2015-04-28 Pacesetter, Inc. Leadless cardiac pacemaker with anti-unscrewing feature
US9126032B2 (en) 2010-12-13 2015-09-08 Pacesetter, Inc. Pacemaker retrieval systems and methods
EP2651494B1 (en) 2010-12-13 2017-02-15 Pacesetter, Inc. Delivery catheter
CN103328040B (zh) 2010-12-20 2016-09-14 内诺斯蒂姆股份有限公司 具有径向固定机构的无导线起搏器
JP2014506936A (ja) * 2011-03-03 2014-03-20 アラーガン インコーポレイテッド シリコーンベースの眼科製剤
WO2013067496A2 (en) 2011-11-04 2013-05-10 Nanostim, Inc. Leadless cardiac pacemaker with integral battery and redundant welds
US9802054B2 (en) 2012-08-01 2017-10-31 Pacesetter, Inc. Biostimulator circuit with flying cell
JP2018513210A (ja) * 2015-03-25 2018-05-24 ゲーツェーテー ゲーエムベーハー 化粧品及び化粧品を製造するためのコンセントレート
CA3020157C (en) * 2016-04-04 2024-01-16 Drug Delivery Solutions Limited Topical composition comprising tacrolimus
EP3542788A1 (en) 2018-03-19 2019-09-25 MC2 Therapeutics Limited Topical composition comprising calcipotriol and betamethasone dipropionate
JP2024544080A (ja) * 2021-12-16 2024-11-27 ザ プロクター アンド ギャンブル カンパニー ヘアコンディショニング組成物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08133979A (ja) * 1994-09-16 1996-05-28 Sando Yakuhin Kk 局所適用薬剤組成物
CN100335063C (zh) * 1994-10-26 2007-09-05 诺瓦蒂斯有限公司 药物组合物
GB2327610B (en) * 1994-11-04 1999-06-02 Novartis Ag Macrolide compositions
WO1997024112A1 (en) * 1995-12-28 1997-07-10 Yoshitomi Pharmaceutical Industries, Ltd. External preparation
GB9601120D0 (en) * 1996-01-19 1996-03-20 Sandoz Ltd Organic compounds
PT1014916E (pt) * 1997-08-18 2002-06-28 Neubourg Stephanie Espuma creme de proteccao dermatologica
ME00189B (me) * 1998-03-26 2011-02-10 Astellas Pharma Inc Preparati sa neprekidnim oslobađanjem
GB9826656D0 (en) * 1998-12-03 1999-01-27 Novartis Ag Organic compounds
JP2001064164A (ja) * 1999-06-23 2001-03-13 Health Science Center:Kk 止痒皮膚塗布剤
GB0003932D0 (en) * 2000-02-18 2000-04-12 Novartis Ag Pharmaceutical compositions
PE20030828A1 (es) * 2002-03-04 2003-11-04 Novartis Ag Composicion oftalmica que comprende ascomicina
GB0218996D0 (en) * 2002-08-14 2002-09-25 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
WO2004087141B1 (en) 2005-01-06
AU2004226821A1 (en) 2004-10-14
NO20055136L (no) 2006-01-04
NO20055136D0 (no) 2005-11-02
MXPA05010708A (es) 2005-12-12
CA2521250A1 (en) 2004-10-14
JP2006522059A (ja) 2006-09-28
MXPA05010703A (es) 2005-12-12
WO2004087141A1 (en) 2004-10-14
RS20050739A (sr) 2007-11-15
GB0307866D0 (en) 2003-05-14
EP1613314A1 (en) 2006-01-11
IS8105A (is) 2005-10-31
CN1767826A (zh) 2006-05-03
US20070276004A1 (en) 2007-11-29

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.