BRPI0409317A - indole or substituted indoline derivative, pharmaceutical composition, and use thereof - Google Patents

indole or substituted indoline derivative, pharmaceutical composition, and use thereof

Info

Publication number
BRPI0409317A
BRPI0409317A BRPI0409317-8A BRPI0409317A BRPI0409317A BR PI0409317 A BRPI0409317 A BR PI0409317A BR PI0409317 A BRPI0409317 A BR PI0409317A BR PI0409317 A BRPI0409317 A BR PI0409317A
Authority
BR
Brazil
Prior art keywords
pharmaceutical composition
indole
indoline derivative
substituted indoline
substituted
Prior art date
Application number
BRPI0409317-8A
Other languages
Portuguese (pt)
Inventor
Nikolay Khanzhin
Mario Rottlonder
William Patrick Watson
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Priority claimed from PCT/DK2004/000283 external-priority patent/WO2004096767A1/en
Publication of BRPI0409317A publication Critical patent/BRPI0409317A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"DERIVADO DE INDOL OU INDOLINA SUBSTITUìDO, COMPOSIçãO FARMACêUTICA, E, USO DA MESMA". A presente invenção refere-se a derivados de anilina da fórmula geral I ou seus sais farmaceuticamente aceitáveis, e ao uso dos mesmos."INDOL OR DERIVED INDOLINE DERIVATIVE, PHARMACEUTICAL COMPOSITION, AND USE OF THE SAME". The present invention relates to aniline derivatives of the general formula I or pharmaceutically acceptable salts thereof, and the use thereof.

BRPI0409317-8A 2003-04-25 2004-04-23 indole or substituted indoline derivative, pharmaceutical composition, and use thereof BRPI0409317A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200300631 2003-04-25
PCT/DK2004/000283 WO2004096767A1 (en) 2003-04-25 2004-04-23 Sustituted indoline and indole derivatives

Publications (1)

Publication Number Publication Date
BRPI0409317A true BRPI0409317A (en) 2006-04-25

Family

ID=58707218

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0409317-8A BRPI0409317A (en) 2003-04-25 2004-04-23 indole or substituted indoline derivative, pharmaceutical composition, and use thereof

Country Status (10)

Country Link
KR (1) KR20060004957A (en)
CN (1) CN1777582A (en)
AR (1) AR044517A1 (en)
BR (1) BRPI0409317A (en)
CA (1) CA2523102A1 (en)
EA (1) EA200501669A1 (en)
IS (1) IS8002A (en)
NZ (1) NZ541999A (en)
UA (1) UA80190C2 (en)
ZA (1) ZA200507186B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103508960B (en) * 2012-06-29 2017-12-12 江苏先声药业有限公司 Benzheterocyclic derivatives
CN108863893A (en) * 2018-07-09 2018-11-23 湖南博隽生物医药有限公司 Indolinyl derivative and its application in drug
CN112010808B (en) * 2019-05-31 2021-11-30 上海挚盟医药科技有限公司 tetrahydro-1H-benzazepine compounds as potassium channel modulators, and preparation and application thereof

Also Published As

Publication number Publication date
CA2523102A1 (en) 2004-11-11
CN1777582A (en) 2006-05-24
KR20060004957A (en) 2006-01-16
EA200501669A1 (en) 2006-04-28
AR044517A1 (en) 2005-09-14
ZA200507186B (en) 2006-11-29
IS8002A (en) 2005-08-29
NZ541999A (en) 2009-03-31
UA80190C2 (en) 2007-08-27

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Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law

Free format text: REFERENTE AS 7A E 8A ANUIDADES.

B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.