BRPI0410020A - composto e/ou um seu sal ou estereoisÈmero farmaceuticamente aceitável, processo para preparar e uso do mesmo, composição farmacêutica, e, kit farmacêutico - Google Patents

composto e/ou um seu sal ou estereoisÈmero farmaceuticamente aceitável, processo para preparar e uso do mesmo, composição farmacêutica, e, kit farmacêutico

Info

Publication number
BRPI0410020A
BRPI0410020A BRPI0410020-4A BRPI0410020A BRPI0410020A BR PI0410020 A BRPI0410020 A BR PI0410020A BR PI0410020 A BRPI0410020 A BR PI0410020A BR PI0410020 A BRPI0410020 A BR PI0410020A
Authority
BR
Brazil
Prior art keywords
preparing
compound
pharmaceutically acceptable
acceptable salt
pharmaceutical
Prior art date
Application number
BRPI0410020-4A
Other languages
English (en)
Inventor
Nicoletta Almirante
Ennio Ongini
Piero Del Soldato
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Publication of BRPI0410020A publication Critical patent/BRPI0410020A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrrole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

"COMPOSTO E/OU UM SEU SAL OU ESTEREOISÈMERO FARMACEUTICAMENTE ACEITáVEL, PROCESSO PARA PREPARAR E USO DO MESMO, COMPOSIçãO FARMACêUTICA, E, KIT FARMACêUTICO". São descritos nitro-derivados de captopril possuindo atividade farmacológica melhorada e tolerabilidade intensificada. Podem ser empregados para o tratamento ou a profilaxia de doenças cardiovasculares, inflamatórias e renais.
BRPI0410020-4A 2003-05-28 2004-05-24 composto e/ou um seu sal ou estereoisÈmero farmaceuticamente aceitável, processo para preparar e uso do mesmo, composição farmacêutica, e, kit farmacêutico BRPI0410020A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03101553 2003-05-28
PCT/EP2004/050899 WO2004106300A1 (en) 2003-05-28 2004-05-24 Captopril derivatives

Publications (1)

Publication Number Publication Date
BRPI0410020A true BRPI0410020A (pt) 2006-04-25

Family

ID=33483995

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0410020-4A BRPI0410020A (pt) 2003-05-28 2004-05-24 composto e/ou um seu sal ou estereoisÈmero farmaceuticamente aceitável, processo para preparar e uso do mesmo, composição farmacêutica, e, kit farmacêutico

Country Status (15)

Country Link
US (1) US7169805B2 (pt)
EP (1) EP1626955A1 (pt)
JP (1) JP4649410B2 (pt)
KR (1) KR20060013413A (pt)
CN (1) CN1795173A (pt)
AR (1) AR044568A1 (pt)
AU (1) AU2004242799A1 (pt)
BR (1) BRPI0410020A (pt)
CA (1) CA2527382A1 (pt)
MX (1) MXPA05012758A (pt)
NO (1) NO20056199L (pt)
PL (1) PL379168A1 (pt)
RU (1) RU2005135695A (pt)
WO (1) WO2004106300A1 (pt)
ZA (1) ZA200509459B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200616604A (en) 2004-08-26 2006-06-01 Nicholas Piramal India Ltd Nitric oxide releasing prodrugs containing bio-cleavable linker
KR20070053214A (ko) 2004-08-26 2007-05-23 니콜라스 피라말 인디아 리미티드 신규 생분해성 링커를 함유하는 프로드럭
WO2011160974A2 (en) 2010-06-21 2011-12-29 Nicox S.A. Statin derivatives

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
JPS559058A (en) 1978-07-06 1980-01-22 Dainippon Pharmaceut Co Ltd 1-(3-mercapto-2-methylpropanoyl)prolyl amino acid derivative
US4399144A (en) * 1980-04-30 1983-08-16 John Wyeth And Brother Limited Pyridinium salts
AU4200489A (en) 1988-08-26 1990-03-23 Sepracor, Inc. Derivatives and precursors of captopril and its analogues
US5380758A (en) * 1991-03-29 1995-01-10 Brigham And Women's Hospital S-nitrosothiols as smooth muscle relaxants and therapeutic uses thereof
GB2300635B (en) * 1994-01-28 1998-06-17 Cal Int Ltd A pharmaceutical product comprising a salicylate of an esterifiable ace-inhibitor
UA58494C2 (uk) * 1995-06-07 2003-08-15 Зенека Лімітед Похідні n-гетероарилпіридинсульфонаміду, фармацевтична композиція, спосіб одержання та спосіб протидії впливам ендотеліну
GB9517998D0 (en) * 1995-09-04 1995-11-08 Bioglan Lab Ltd Compositions and device for their administration
IT1276071B1 (it) 1995-10-31 1997-10-24 Nicox Ltd Compositi ad attivita' anti-infiammatoria
US6294517B1 (en) * 1996-02-02 2001-09-25 Nitromed, Inc. Compositions and kits comprising alpha-adrenergic receptor antagonists and nitric oxide donors and methods of use
JPH09291075A (ja) * 1996-03-01 1997-11-11 Sankyo Co Ltd チアゾリジン類
US6331543B1 (en) * 1996-11-01 2001-12-18 Nitromed, Inc. Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use
IT1295694B1 (it) 1996-11-14 1999-05-27 Nicox Sa Nitrossi derivati per la preparazione di medicamenti ad attivita antitrombinica
IT1292426B1 (it) * 1997-06-27 1999-02-08 Nicox Sa Sali nitrati di ace-inibitori
JPH1171279A (ja) 1997-08-27 1999-03-16 Sankyo Co Ltd チアゾリジン類を有効成分として含有する狭心症予防剤又は治療剤
US6223744B1 (en) * 1999-03-16 2001-05-01 Multi-Vet Ltd. Wearable aerosol delivery apparatus
IT1311923B1 (it) 1999-04-13 2002-03-20 Nicox Sa Composti farmaceutici.
IT1311924B1 (it) 1999-04-13 2002-03-20 Nicox Sa Composti farmaceutici.
IT1314184B1 (it) 1999-08-12 2002-12-06 Nicox Sa Composizioni farmaceutiche per la terapia di condizioni di stressossidativo
US6677356B1 (en) * 1999-08-24 2004-01-13 Medicure International Inc. Treatment of cardiovascular and related pathologies
DK1216038T3 (da) * 1999-08-30 2005-12-27 Sanofi Aventis Deutschland Anvendelse af inhibitorer af reninangiotensinsystemet ved forebyggelsen af cardiovaskulære hændelser
JP2003521496A (ja) * 2000-01-26 2003-07-15 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー Ａｃｅ阻害剤−バソプレッシンアンタゴニストの組み合わせ
EP1337283A4 (en) * 2000-10-27 2005-05-18 Nitromed Inc METHOD FOR THE TREATMENT OF VASCULAR DISORDERS MARKED BY STICK OXIDE DEFICIENCY
ITMI20011240A1 (it) * 2001-06-13 2002-12-13 Nicox Sa Farmaci per le vasculopatie

Also Published As

Publication number Publication date
KR20060013413A (ko) 2006-02-09
CA2527382A1 (en) 2004-12-09
RU2005135695A (ru) 2006-05-27
JP2006528230A (ja) 2006-12-14
PL379168A1 (pl) 2006-07-24
WO2004106300A1 (en) 2004-12-09
AU2004242799A1 (en) 2004-12-09
NO20056199L (no) 2006-02-13
JP4649410B2 (ja) 2011-03-09
US20040259808A1 (en) 2004-12-23
EP1626955A1 (en) 2006-02-22
US7169805B2 (en) 2007-01-30
MXPA05012758A (es) 2006-02-13
CN1795173A (zh) 2006-06-28
ZA200509459B (en) 2006-11-29
AR044568A1 (es) 2005-09-21

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.