BRPI0410173A - composição farmacêutica para a prevenção e tratamento da viciação em nicotina em um mamìfero - Google Patents
composição farmacêutica para a prevenção e tratamento da viciação em nicotina em um mamìferoInfo
- Publication number
- BRPI0410173A BRPI0410173A BRPI0410173-1A BRPI0410173A BRPI0410173A BR PI0410173 A BRPI0410173 A BR PI0410173A BR PI0410173 A BRPI0410173 A BR PI0410173A BR PI0410173 A BRPI0410173 A BR PI0410173A
- Authority
- BR
- Brazil
- Prior art keywords
- addiction
- treatment
- mammal
- prevention
- pharmaceutical composition
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 4
- 206010057852 Nicotine dependence Diseases 0.000 title abstract 3
- 208000025569 Tobacco Use disease Diseases 0.000 title abstract 3
- 241000124008 Mammalia Species 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 206010012335 Dependence Diseases 0.000 abstract 4
- 241000208125 Nicotiana Species 0.000 abstract 2
- 235000002637 Nicotiana tabacum Nutrition 0.000 abstract 2
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 abstract 1
- 229940123158 Cannabinoid CB1 receptor antagonist Drugs 0.000 abstract 1
- 102000019315 Nicotinic acetylcholine receptors Human genes 0.000 abstract 1
- 108050006807 Nicotinic acetylcholine receptors Proteins 0.000 abstract 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 abstract 1
- 230000003542 behavioural effect Effects 0.000 abstract 1
- 239000003555 cannabinoid 1 receptor antagonist Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229960002715 nicotine Drugs 0.000 abstract 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 abstract 1
- 239000004031 partial agonist Substances 0.000 abstract 1
- 201000009032 substance abuse Diseases 0.000 abstract 1
- 231100000736 substance abuse Toxicity 0.000 abstract 1
- 208000011117 substance-related disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Addiction (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"COMPOSIçãO FARMACêUTICA PARA A PREVENçãO E TRATAMENTO DA VICIAçãO EM NICOTINA EM UM MAMìFERO". A presente invenção refere-se a composições farmacêuticas para o tratamento da dependência ou viciação em nicotina, dependência ou viciação em tabaco, redução dos sintomas de abstinência de nicotina ou ajuda durante a cessação ou redução de consumo de tabaco ou abuso de substâncias ou outras dependências comportamentais. As composições farmacêuticas compreendem uma combinação terapeuticamente eficaz de um agonista parcial do receptor nicotínico e um antagonista do receptor CB1 e um veículo farmaceuticamente aceitável. O método de utilização destes compostos é também divulgado.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46942903P | 2003-05-09 | 2003-05-09 | |
| PCT/IB2004/001552 WO2004098580A2 (en) | 2003-05-09 | 2004-05-05 | A pharmaceutical composition for the prevention and treatment of nicotine addiction in a mammal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0410173A true BRPI0410173A (pt) | 2006-05-16 |
Family
ID=33435233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0410173-1A BRPI0410173A (pt) | 2003-05-09 | 2004-05-05 | composição farmacêutica para a prevenção e tratamento da viciação em nicotina em um mamìfero |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20040224963A1 (pt) |
| EP (1) | EP1624895A2 (pt) |
| JP (1) | JP2006525992A (pt) |
| KR (1) | KR20060009314A (pt) |
| CN (1) | CN1784243A (pt) |
| AU (1) | AU2004237153A1 (pt) |
| BR (1) | BRPI0410173A (pt) |
| CA (1) | CA2525225A1 (pt) |
| CO (1) | CO5700713A2 (pt) |
| MX (1) | MXPA05012088A (pt) |
| NO (1) | NO20055767L (pt) |
| RU (1) | RU2005131497A (pt) |
| WO (1) | WO2004098580A2 (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE521512C2 (sv) | 2001-06-25 | 2003-11-11 | Niconovum Ab | Anordning för administrering av en substans till främre delen av en individs munhåla |
| KR20050088194A (ko) | 2002-12-19 | 2005-09-02 | 머크 앤드 캄파니 인코포레이티드 | 치환된 아미드 |
| ATE359075T1 (de) | 2002-12-20 | 2007-05-15 | Niconovum Ab | Chemisch und physikalisch stabiles teilchenförmiges material enthaltend nikotin und microcrystalline cellulose |
| JP5694645B2 (ja) | 2006-03-16 | 2015-04-01 | ニコノヴァム エービーNiconovum Ab | 改善された嗅ぎたばこ組成物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2692575B1 (fr) * | 1992-06-23 | 1995-06-30 | Sanofi Elf | Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| EP0937077B1 (en) * | 1996-10-30 | 2006-05-17 | Pfizer Inc. | Pyridone-fused azabicyclic- or cytisine derivatives, their preparation and their use in addiction therapy |
| FR2758723B1 (fr) * | 1997-01-28 | 1999-04-23 | Sanofi Sa | Utilisation des antagonistes des recepteurs aux cannabinoides centraux pour la preparation de medicaments |
| IL136727A0 (en) * | 1997-12-31 | 2001-06-14 | Pfizer Prod Inc | Aryl fused azapolycyclic compounds |
| WO1999055680A1 (en) * | 1998-04-29 | 1999-11-04 | Pfizer Products Inc. | Aryl fused azapolycyclic compounds |
| FR2804604B1 (fr) * | 2000-02-09 | 2005-05-27 | Sanofi Synthelabo | Utilisation d'un antagoniste des recepteurs aux cannabinoides centraux pour la preparation de medicaments utiles pour faciliter l'arret de la consommation de tabac |
| TWI231757B (en) * | 2001-09-21 | 2005-05-01 | Solvay Pharm Bv | 1H-Imidazole derivatives having CB1 agonistic, CB1 partial agonistic or CB1-antagonistic activity |
-
2004
- 2004-03-04 US US10/793,112 patent/US20040224963A1/en not_active Abandoned
- 2004-05-05 AU AU2004237153A patent/AU2004237153A1/en not_active Abandoned
- 2004-05-05 CN CNA2004800126254A patent/CN1784243A/zh active Pending
- 2004-05-05 WO PCT/IB2004/001552 patent/WO2004098580A2/en not_active Ceased
- 2004-05-05 KR KR1020057021204A patent/KR20060009314A/ko not_active Ceased
- 2004-05-05 EP EP04731228A patent/EP1624895A2/en not_active Withdrawn
- 2004-05-05 MX MXPA05012088A patent/MXPA05012088A/es not_active Application Discontinuation
- 2004-05-05 JP JP2006506619A patent/JP2006525992A/ja active Pending
- 2004-05-05 BR BRPI0410173-1A patent/BRPI0410173A/pt not_active IP Right Cessation
- 2004-05-05 CA CA002525225A patent/CA2525225A1/en not_active Abandoned
- 2004-05-05 RU RU2005131497/15A patent/RU2005131497A/ru not_active Application Discontinuation
-
2005
- 2005-11-09 CO CO05113614A patent/CO5700713A2/es not_active Application Discontinuation
- 2005-12-05 NO NO20055767A patent/NO20055767L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20040224963A1 (en) | 2004-11-11 |
| KR20060009314A (ko) | 2006-01-31 |
| EP1624895A2 (en) | 2006-02-15 |
| WO2004098580A2 (en) | 2004-11-18 |
| CO5700713A2 (es) | 2006-11-30 |
| CA2525225A1 (en) | 2004-11-18 |
| AU2004237153A1 (en) | 2004-11-18 |
| CN1784243A (zh) | 2006-06-07 |
| NO20055767L (no) | 2005-12-05 |
| WO2004098580A3 (en) | 2005-01-06 |
| JP2006525992A (ja) | 2006-11-16 |
| RU2005131497A (ru) | 2006-06-27 |
| MXPA05012088A (es) | 2006-02-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 4A, 5A, 6A, 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012. |