BRPI0410222A - tratamento de distúrbios bipolares e sintomas associados - Google Patents

tratamento de distúrbios bipolares e sintomas associados

Info

Publication number
BRPI0410222A
BRPI0410222A BRPI0410222-3A BRPI0410222A BRPI0410222A BR PI0410222 A BRPI0410222 A BR PI0410222A BR PI0410222 A BRPI0410222 A BR PI0410222A BR PI0410222 A BRPI0410222 A BR PI0410222A
Authority
BR
Brazil
Prior art keywords
treatment
bipolar
bipolar disorder
mammal
associated symptoms
Prior art date
Application number
BRPI0410222-3A
Other languages
English (en)
Inventor
Earl Laux Giller Jr
Edmund Harrigan
James Herbert Heym
Steven Joseph Romano
Thomas Francis Seeger
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BRPI0410222A publication Critical patent/BRPI0410222A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

"TRATAMENTO DE DISTúRBIOS BIPOLARES E SINTOMAS ASSOCIADOS". A presente invenção refere-se a um método para tratamentos relacionados com distúrbio bipolar num mamífero, incluindo um humano, os tratamentos incluem tratamento de distúrbio bipolar de ciclo rápido, tratamento de sintomas de distúrbio bipolar selecionados do grupo consistindo de obsessão aguda e depressão, tratamento para efetuar a estabilização do humor; tratamento para a prevenção da reincidência em episódios bipolares, e para o tratamento de pensamentos e tendências suicidas associados com o distúrbio bipolar, consistindo na administração ao referido mamífero de uma quantidade eficaz de um composto da fórmula (I): ou um sal de adição ácido farmaceuticamente aceitável seu, em que Ar, n, X, e Y são como definidos.
BRPI0410222-3A 2003-05-16 2004-05-12 tratamento de distúrbios bipolares e sintomas associados BRPI0410222A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47145003P 2003-05-16 2003-05-16
PCT/IB2004/001601 WO2004100957A1 (en) 2003-05-16 2004-05-12 Treatment of bipolar disorders and associated symptoms

Publications (1)

Publication Number Publication Date
BRPI0410222A true BRPI0410222A (pt) 2006-05-09

Family

ID=33452446

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0410222-3A BRPI0410222A (pt) 2003-05-16 2004-05-12 tratamento de distúrbios bipolares e sintomas associados

Country Status (13)

Country Link
US (1) US20050038036A1 (pt)
EP (1) EP1626723A1 (pt)
JP (1) JP2007516955A (pt)
KR (1) KR20060009938A (pt)
CN (1) CN1780626A (pt)
AR (1) AR046586A1 (pt)
AU (1) AU2004237961A1 (pt)
BR (1) BRPI0410222A (pt)
CA (1) CA2525326A1 (pt)
MX (1) MXPA05012320A (pt)
TW (1) TW200509929A (pt)
WO (1) WO2004100957A1 (pt)
ZA (1) ZA200508523B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE424825T1 (de) 2001-07-20 2009-03-15 Psychogenics Inc Behandlung von hyperaktivitätsstörungen und aufmerksamkeitsdefiziten
MY144968A (en) * 2005-04-11 2011-11-30 Xenon Pharmaceuticals Inc Spiro-oxindole compounds and their uses as therapeutic agents
MY145694A (en) 2005-04-11 2012-03-30 Xenon Pharmaceuticals Inc Spiroheterocyclic compounds and their uses as therapeutic agents
AR056317A1 (es) * 2005-04-20 2007-10-03 Xenon Pharmaceuticals Inc Compuestos de oxindol y composicion farmaceutica
US20100222353A1 (en) * 2006-01-27 2010-09-02 Pfizer Products Inc. Aminophthalazine derivative compounds
CN100491375C (zh) * 2006-07-01 2009-05-27 浙江美诺华药物化学有限公司 一种齐拉西酮的制备方法
JP2010506853A (ja) * 2006-10-12 2010-03-04 ゼノン・ファーマシューティカルズ・インコーポレイテッド 疼痛などのナトリウムチャネル媒介性の疾患の処置のための、スピロ（［３，２−フロ］ピリジン−３，３’−インドール）−２’（１’ｈ）−オン誘導体および関連化合物
AR063280A1 (es) * 2006-10-12 2009-01-21 Xenon Pharmaceuticals Inc Uso de compuestos de espiro-oxindol como agentes terapeuticos
AU2007307635A1 (en) * 2006-10-12 2008-04-17 Xenon Pharmaceuticals Inc. Tricyclic spiro-oxindole derivatives and their uses as therapeutic agents
CN105218565A (zh) 2008-10-17 2016-01-06 泽农医药公司 螺羟吲哚化合物及其作为治疗剂的用途
CA2741024A1 (en) * 2008-10-17 2010-04-22 Xenon Pharmaceuticals Inc. Spiro-oxindole compounds and their use as therapeutic agents
AR077252A1 (es) 2009-06-29 2011-08-10 Xenon Pharmaceuticals Inc Enantiomeros de compuestos de espirooxindol y sus usos como agentes terapeuticos
US20110086899A1 (en) * 2009-10-14 2011-04-14 Xenon Pharmaceuticals Inc. Pharmaceutical compositions for oral administration
MX2012004373A (es) * 2009-10-14 2012-06-28 Xenon Pharmaceuticals Inc Metodos sinteticos para compuestos espiro-oxoindol.
CA2788440A1 (en) 2010-02-26 2011-09-01 Xenon Pharmaceuticals Inc. Pharmaceutical compositions of spiro-oxindole compound for topical administration and their use as therapeutic agents
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
TW201636017A (zh) 2015-02-05 2016-10-16 梯瓦製藥國際有限責任公司 以螺吲哚酮化合物之局部調配物治療帶狀疱疹後遺神經痛之方法
KR20240161147A (ko) 2022-03-14 2024-11-12 슬랩 파마슈티컬스 엘엘씨 다중 사이클릭 화합물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4883795A (en) * 1988-01-22 1989-11-28 Pfizer Inc. Piperazinyl-heterocyclic compounds
US4831031A (en) * 1988-01-22 1989-05-16 Pfizer Inc. Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity
IL125951A (en) * 1997-09-05 2003-09-17 Pfizer Prod Inc A pharmaceutical composition comprising a piperazinyl-heterocyclic compound for treating tourette's syndrome, obsessive compulsive disorder, chronic motor or vocal tic disorder in a mammal
IL127497A (en) * 1997-12-18 2002-07-25 Pfizer Prod Inc Medicinal products containing piperazinyl-heterocyclic compounds for the treatment of psychiatric disorders
US6387904B2 (en) * 1998-05-18 2002-05-14 Pfizer Inc Method of treating glaucoma and ischemic retinopathy
IL139591A0 (en) * 1998-05-29 2002-02-10 Lilly Co Eli Combination therapy for treatment of bipolar disorders

Also Published As

Publication number Publication date
JP2007516955A (ja) 2007-06-28
EP1626723A1 (en) 2006-02-22
CA2525326A1 (en) 2004-11-25
MXPA05012320A (es) 2006-01-30
ZA200508523B (en) 2007-04-25
WO2004100957A1 (en) 2004-11-25
US20050038036A1 (en) 2005-02-17
KR20060009938A (ko) 2006-02-01
AU2004237961A1 (en) 2004-11-25
TW200509929A (en) 2005-03-16
CN1780626A (zh) 2006-05-31
AR046586A1 (es) 2005-12-14

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2142 DE 24/01/2012.