BRPI0410222A - tratamento de distúrbios bipolares e sintomas associados - Google Patents

tratamento de distúrbios bipolares e sintomas associados

Info

Publication number
BRPI0410222A
BRPI0410222A BRPI0410222-3A BRPI0410222A BRPI0410222A BR PI0410222 A BRPI0410222 A BR PI0410222A BR PI0410222 A BRPI0410222 A BR PI0410222A BR PI0410222 A BRPI0410222 A BR PI0410222A
Authority
BR
Brazil
Prior art keywords
treatment
bipolar
bipolar disorder
mammal
associated symptoms
Prior art date
Application number
BRPI0410222-3A
Other languages
English (en)
Inventor
Earl Laux Giller Jr
Edmund Harrigan
James Herbert Heym
Steven Joseph Romano
Thomas Francis Seeger
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BRPI0410222A publication Critical patent/BRPI0410222A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

"TRATAMENTO DE DISTúRBIOS BIPOLARES E SINTOMAS ASSOCIADOS". A presente invenção refere-se a um método para tratamentos relacionados com distúrbio bipolar num mamífero, incluindo um humano, os tratamentos incluem tratamento de distúrbio bipolar de ciclo rápido, tratamento de sintomas de distúrbio bipolar selecionados do grupo consistindo de obsessão aguda e depressão, tratamento para efetuar a estabilização do humor; tratamento para a prevenção da reincidência em episódios bipolares, e para o tratamento de pensamentos e tendências suicidas associados com o distúrbio bipolar, consistindo na administração ao referido mamífero de uma quantidade eficaz de um composto da fórmula (I): ou um sal de adição ácido farmaceuticamente aceitável seu, em que Ar, n, X, e Y são como definidos.
BRPI0410222-3A 2003-05-16 2004-05-12 tratamento de distúrbios bipolares e sintomas associados BRPI0410222A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47145003P 2003-05-16 2003-05-16
PCT/IB2004/001601 WO2004100957A1 (en) 2003-05-16 2004-05-12 Treatment of bipolar disorders and associated symptoms

Publications (1)

Publication Number Publication Date
BRPI0410222A true BRPI0410222A (pt) 2006-05-09

Family

ID=33452446

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0410222-3A BRPI0410222A (pt) 2003-05-16 2004-05-12 tratamento de distúrbios bipolares e sintomas associados

Country Status (13)

Country Link
US (1) US20050038036A1 (pt)
EP (1) EP1626723A1 (pt)
JP (1) JP2007516955A (pt)
KR (1) KR20060009938A (pt)
CN (1) CN1780626A (pt)
AR (1) AR046586A1 (pt)
AU (1) AU2004237961A1 (pt)
BR (1) BRPI0410222A (pt)
CA (1) CA2525326A1 (pt)
MX (1) MXPA05012320A (pt)
TW (1) TW200509929A (pt)
WO (1) WO2004100957A1 (pt)
ZA (1) ZA200508523B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2323451T7 (es) 2001-07-20 2011-08-01 Psychogenics Inc. Tratamiento para el trastorno de hiperactividad con deficit de atencion.
AR053710A1 (es) * 2005-04-11 2007-05-16 Xenon Pharmaceuticals Inc Compuestos espiroheterociclicos y sus usos como agentes terapeuticos
AR056968A1 (es) * 2005-04-11 2007-11-07 Xenon Pharmaceuticals Inc Compuestos espiro-oxindol y composiciones farmacéuticas
AR056317A1 (es) * 2005-04-20 2007-10-03 Xenon Pharmaceuticals Inc Compuestos de oxindol y composicion farmaceutica
JP2009524637A (ja) * 2006-01-27 2009-07-02 ファイザー・プロダクツ・インク アミノフタラジン誘導体化合物
CN100491375C (zh) * 2006-07-01 2009-05-27 浙江美诺华药物化学有限公司 一种齐拉西酮的制备方法
WO2008060789A2 (en) * 2006-10-12 2008-05-22 Xenon Pharmaceuticals Inc. Use of spiro-oxindole compounds as therapeutic agents
AU2007307635A1 (en) * 2006-10-12 2008-04-17 Xenon Pharmaceuticals Inc. Tricyclic spiro-oxindole derivatives and their uses as therapeutic agents
US20110294842A9 (en) * 2006-10-12 2011-12-01 Xenon Pharmaceuticals Inc. Spiro (furo [3, 2-c] pyridine-3-3' -indol) -2' (1'h)-one derivatives and related compounds for the treatment of sodium-channel mediated diseases, such as pain
CA2741024A1 (en) * 2008-10-17 2010-04-22 Xenon Pharmaceuticals Inc. Spiro-oxindole compounds and their use as therapeutic agents
JO3032B1 (ar) * 2008-10-17 2016-09-05 Xenon Pharmaceuticals Inc مركبات سبيرو – اوكسندول وإستعمالاتها كعوامل علاجية.
AR077252A1 (es) 2009-06-29 2011-08-10 Xenon Pharmaceuticals Inc Enantiomeros de compuestos de espirooxindol y sus usos como agentes terapeuticos
KR20120099429A (ko) 2009-10-14 2012-09-10 제논 파마슈티칼스 인크. 스피로-옥스인돌 화합물의 합성 방법
US20110086899A1 (en) * 2009-10-14 2011-04-14 Xenon Pharmaceuticals Inc. Pharmaceutical compositions for oral administration
WO2011106729A2 (en) 2010-02-26 2011-09-01 Xenon Pharmaceuticals Inc. Pharmaceutical compositions of spiro-oxindole compound for topical administration and their use as therapeutic agents
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
WO2016127068A1 (en) 2015-02-05 2016-08-11 Teva Pharmaceuticals International Gmbh Methods of treating postherpetic neuralgia with a topical formulation of a spiro-oxindole compound
AU2023235233A1 (en) 2022-03-14 2024-09-12 Slap Pharmaceuticals Llc Multicyclic compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4831031A (en) * 1988-01-22 1989-05-16 Pfizer Inc. Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity
US4883795A (en) * 1988-01-22 1989-11-28 Pfizer Inc. Piperazinyl-heterocyclic compounds
IL125951A (en) * 1997-09-05 2003-09-17 Pfizer Prod Inc A pharmaceutical composition comprising a piperazinyl-heterocyclic compound for treating tourette's syndrome, obsessive compulsive disorder, chronic motor or vocal tic disorder in a mammal
IL127497A (en) * 1997-12-18 2002-07-25 Pfizer Prod Inc Medicinal products containing piperazinyl-heterocyclic compounds for the treatment of psychiatric disorders
US6387904B2 (en) * 1998-05-18 2002-05-14 Pfizer Inc Method of treating glaucoma and ischemic retinopathy
BR9911068A (pt) * 1998-05-29 2001-02-06 Lilly Co Eli Terapia combinada para tratamento de distúrbios bipolares

Also Published As

Publication number Publication date
WO2004100957A1 (en) 2004-11-25
CA2525326A1 (en) 2004-11-25
CN1780626A (zh) 2006-05-31
AU2004237961A1 (en) 2004-11-25
JP2007516955A (ja) 2007-06-28
ZA200508523B (en) 2007-04-25
TW200509929A (en) 2005-03-16
KR20060009938A (ko) 2006-02-01
US20050038036A1 (en) 2005-02-17
MXPA05012320A (es) 2006-01-30
AR046586A1 (es) 2005-12-14
EP1626723A1 (en) 2006-02-22

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2142 DE 24/01/2012.