BRPI0410861A - methods and compositions for the production of amino acids - Google Patents

methods and compositions for the production of amino acids

Info

Publication number
BRPI0410861A
BRPI0410861A BRPI0410861-2A BRPI0410861A BRPI0410861A BR PI0410861 A BRPI0410861 A BR PI0410861A BR PI0410861 A BRPI0410861 A BR PI0410861A BR PI0410861 A BRPI0410861 A BR PI0410861A
Authority
BR
Brazil
Prior art keywords
compositions
methods
production
amino acids
amino acid
Prior art date
Application number
BRPI0410861-2A
Other languages
Portuguese (pt)
Inventor
Richard B Bailey
Paul Blomquist
Reed Doten
Edward M Driggers
Kevin T Madden
Jessica O'leary
George A O'toole
Joshua Trueheart
Michael J Walbridge
Peter Yorgey
Original Assignee
Microbia Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbia Inc filed Critical Microbia Inc
Publication of BRPI0410861A publication Critical patent/BRPI0410861A/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1007—Methyltransferases (general) (2.1.1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

"MéTODOS E COMPOSIçõES PARA A PRODUçãO DE AMINOáCIDOS". Métodos e composições para a produção de aminoácido usando bactérias geneticamente modificadas são divulgados."METHODS AND COMPOSITIONS FOR AMINO ACID PRODUCTION". Methods and compositions for amino acid production using genetically modified bacteria are disclosed.

BRPI0410861-2A 2003-05-30 2004-06-01 methods and compositions for the production of amino acids BRPI0410861A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47500003P 2003-05-30 2003-05-30
US55186004P 2004-03-10 2004-03-10
PCT/US2004/017513 WO2004108894A2 (en) 2003-05-30 2004-06-01 Methods and compositions for amino acid production

Publications (1)

Publication Number Publication Date
BRPI0410861A true BRPI0410861A (en) 2006-05-23

Family

ID=33514039

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0410861-2A BRPI0410861A (en) 2003-05-30 2004-06-01 methods and compositions for the production of amino acids

Country Status (7)

Country Link
EP (1) EP1633851A4 (en)
JP (1) JP2007525951A (en)
KR (1) KR20060018868A (en)
AU (1) AU2004245988A1 (en)
BR (1) BRPI0410861A (en)
CA (1) CA2526365A1 (en)
WO (1) WO2004108894A2 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2275424C2 (en) 2003-12-05 2006-04-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) Method for preparing l-threonine by using bacterium belonging to genus escherichia
CA2549298C (en) * 2003-12-05 2014-02-25 Ajinomoto Co., Inc. L-threonine producing bacterium belonging to the genus escherichia and method for producing l-threonine
US7723097B2 (en) * 2005-03-11 2010-05-25 Archer-Daniels-Midland Company Escherichia coli strains that over-produce L-threonine and processes for their production
RU2413001C2 (en) * 2005-07-18 2011-02-27 Эвоник Дегусса Гмбх Application of dimethyl disulfide for production of methionine by microorganisms
EP1922405A4 (en) * 2005-08-05 2009-04-01 Univ Michigan State GENES FROM ACTINOBACILLUS SUCCINOGENES 130Z (ATCC 55618) FOR THE PRODUCTION OF CHEMICAL AGENTS FROM ROUTES C4 OF A. succinogenes
JP2007068437A (en) * 2005-09-05 2007-03-22 Chisso Corp Mutant aspartokinase and methods of use
DK2314710T3 (en) 2006-01-04 2016-06-13 Metabolic Explorer Sa A process for the production of methionine by culturing a microorganism modified to enhance the production of cysteine
WO2008033001A1 (en) * 2006-09-15 2008-03-20 Cj Cheiljedang Corporation A corynebacteria having enhanced l-lysine productivity and a method of producing l-lysine using the same
KR20080061801A (en) * 2006-12-28 2008-07-03 씨제이제일제당 (주) Polypeptide to improve L-methionine production capacity, microorganisms overexpressing the polypeptide and L-methionine production method using the microorganism
WO2008092956A1 (en) * 2007-02-02 2008-08-07 Evonik Degussa Gmbh Production of l-lysine and l-lysine-containing feed additives
PL2520645T3 (en) 2007-04-11 2015-05-29 Cj Cheiljedang Corp Compositions and methods of producing methionine
US8283152B2 (en) * 2009-08-28 2012-10-09 Cj Cheiljedang Corporation Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism
KR101250651B1 (en) 2010-12-21 2013-04-03 씨제이제일제당 (주) New O-acetylhomoserine sulfhydrylase or mutants, and L-methionine conversion method uging the enzyme
PL2657250T3 (en) * 2010-12-21 2018-02-28 Cj Cheiljedang Corporation Variant polypeptide having homoserine acetyltransferase activity and microorganism expressing same
KR101485222B1 (en) * 2012-10-05 2015-01-22 상지대학교산학협력단 Corynebacterium sp. microorganism having enhanced L-threonine productivity by regulation of dapA activity and a method of producing L-threonine using the same
KR101947959B1 (en) * 2018-05-28 2019-02-13 씨제이제일제당 (주) A modified homoserine dehydrogenase and a method for producing homoserine or L- amino acid derived from homoserine using the same
KR101996769B1 (en) * 2018-12-21 2019-10-01 씨제이제일제당 (주) A homoserine dehydrogenase variant and a method for producing homoserine or L-amino acid derived from homoserine using the same
PE20220018A1 (en) * 2019-06-14 2022-01-11 Cj Cheiljedang Corp COMPOSITION TO PREVENT, TREAT OR IMPROVE GASTROINTESTINAL DISEASES THAT COMPRISES A STRAIN OF THE GENUS CORYNEBACTERIUM AND CULTIVATION OF THE SAME
KR102472559B1 (en) * 2019-06-28 2022-12-01 씨제이제일제당 주식회사 A method of producing sulfur-containing amino acids and derivatives thereof
KR102617168B1 (en) * 2020-12-09 2023-12-21 씨제이제일제당 (주) Shewanella oneidensis-Drived Protein Expressing Microorganism and Method of L-Amino Acid Production Using the Same
AU2023362566A1 (en) 2022-10-20 2025-04-24 Cysbio Aps Genetically modified host cells producing l-serine
WO2025104134A2 (en) 2023-11-14 2025-05-22 Cysbio Aps Expression of biomolecules with improved promoter and tir

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4601983A (en) * 1983-06-15 1986-07-22 Ajinomoto Co., Inc. Coryneform bacteria carrying recombinant plasmids and their use in the fermentative production of L-threonine and L-isoleucine
EP0754756B1 (en) * 1994-03-04 2005-11-09 Ajinomoto Co., Inc. Process for producing l-lysine
WO1999053035A1 (en) * 1998-04-13 1999-10-21 The University Of Georgia Research Foundation, Inc. Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells
US6451564B1 (en) * 1999-07-02 2002-09-17 Massachusetts Institute Of Technology Methods for producing L-isoleucine
DE10239082A1 (en) * 2002-08-26 2004-03-04 Basf Ag Fermentative production of sulfur-containing fine chemicals, useful e.g. as feed additive, by culturing bacteria containing heterologous sequence for O-acetylhomoserine sulfhydrolase

Also Published As

Publication number Publication date
EP1633851A2 (en) 2006-03-15
WO2004108894A3 (en) 2007-11-22
WO2004108894A2 (en) 2004-12-16
EP1633851A4 (en) 2009-04-08
JP2007525951A (en) 2007-09-13
KR20060018868A (en) 2006-03-02
AU2004245988A1 (en) 2004-12-16
CA2526365A1 (en) 2004-12-16

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.

B15K Others concerning applications: alteration of classification

Ipc: C12N 9/02 (2006.01), C12N 9/04 (2006.01), C12N 9/1