BRPI0410968A - combinação unitária de fsh e hcg - Google Patents
combinação unitária de fsh e hcgInfo
- Publication number
- BRPI0410968A BRPI0410968A BRPI0410968-6A BRPI0410968A BRPI0410968A BR PI0410968 A BRPI0410968 A BR PI0410968A BR PI0410968 A BRPI0410968 A BR PI0410968A BR PI0410968 A BRPI0410968 A BR PI0410968A
- Authority
- BR
- Brazil
- Prior art keywords
- hcg
- fsh
- unit combination
- administration
- combination
- Prior art date
Links
- 230000000624 ovulatory effect Effects 0.000 abstract 2
- 102000006771 Gonadotropins Human genes 0.000 abstract 1
- 108010086677 Gonadotropins Proteins 0.000 abstract 1
- 239000002622 gonadotropin Substances 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 238000011269 treatment regimen Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Reproductive Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
"COMBINAçãO UNITáRIA DE FSH E hCG". A presente invenção refere-se a um novo paradigma de indução ovulatória que impõe administração de hCG em combinação com FSH durante todos os estágios de tratamento, onde a razão de FSH para hCG é ajustada para otimizar estimulação ovulatória e minimizar complicações. O uso de composições caracterizadas por várias razões de FSH:HCG permite que o profissional prontamente adapte o regime de tratamento e acomode diferentes metas terapêuticas, bem como respostas individuais a pacientes para administração de gonadotrofina.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/452,926 US20040248784A1 (en) | 2003-06-03 | 2003-06-03 | Unitary combinations of FSH and hCG |
| PCT/IB2004/001813 WO2004105788A1 (en) | 2003-06-03 | 2004-06-02 | UNITARY COMBINATION OF FSH AND hCG |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0410968A true BRPI0410968A (pt) | 2006-07-04 |
Family
ID=33489458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0410968-6A BRPI0410968A (pt) | 2003-06-03 | 2004-06-02 | combinação unitária de fsh e hcg |
Country Status (15)
| Country | Link |
|---|---|
| US (6) | US20040248784A1 (pt) |
| EP (2) | EP2292252B1 (pt) |
| JP (1) | JP2006526609A (pt) |
| KR (2) | KR20070118195A (pt) |
| CN (2) | CN101156945A (pt) |
| AU (1) | AU2004243256B2 (pt) |
| BR (1) | BRPI0410968A (pt) |
| CA (1) | CA2524755A1 (pt) |
| ES (2) | ES2753822T3 (pt) |
| MX (1) | MXPA05012967A (pt) |
| NO (1) | NO20060002L (pt) |
| NZ (1) | NZ543403A (pt) |
| RU (1) | RU2332228C2 (pt) |
| WO (1) | WO2004105788A1 (pt) |
| ZA (1) | ZA200509814B (pt) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040248784A1 (en) * | 2003-06-03 | 2004-12-09 | Marco Filicori | Unitary combinations of FSH and hCG |
| US8260985B2 (en) * | 2007-10-05 | 2012-09-04 | Pano Logic, Inc. | Universal serial bus assistance engine |
| TWI488640B (zh) | 2008-04-16 | 2015-06-21 | 菲瑞茵國際中心股份有限公司 | 藥學製劑 |
| CN102309745B (zh) * | 2008-09-17 | 2013-05-08 | 上海天伟生物制药有限公司 | 一种卵泡刺激素冻干针剂 |
| CN102309744B (zh) * | 2008-09-17 | 2013-05-08 | 上海天伟生物制药有限公司 | 一种绒毛膜促性腺激素冻干针剂 |
| TWI532495B (zh) * | 2009-10-05 | 2016-05-11 | 菲瑞茵國際中心股份有限公司 | 藥學製劑 |
| US9320778B2 (en) | 2010-09-29 | 2016-04-26 | Ferring B.V. | Method for controlled ovarian stimulation with combined FSH and hCG |
| WO2012120535A2 (en) * | 2011-02-03 | 2012-09-13 | Sanzyme Limited | A composition comprising highly purified chorionic gonadotropin, it's formulation and uses of the same |
| WO2012127501A2 (en) * | 2011-03-11 | 2012-09-27 | Sanzyme Limited | Composition for improving endometrial thickness during ovarian stimulation |
| WO2012127500A2 (en) * | 2011-03-11 | 2012-09-27 | Sanzyme Limited | Composition for spermatogenesis |
| CA3163525A1 (en) | 2011-03-31 | 2012-10-04 | Ferring Bv. | Pharmaceutical preparation |
| AU2012286048A1 (en) * | 2011-07-18 | 2014-02-20 | Arts Biologics A/S | Long acting luteinizing hormone (LH) compound |
| JO3092B1 (ar) * | 2011-08-08 | 2017-03-15 | Ferring Bv | مركب لتحفيز مسيطر عليه للمبيض |
| US20150272622A1 (en) * | 2011-12-22 | 2015-10-01 | Previvo Genetics, Llc | Recovery and processing of human embryos formed in vivo |
| GB201517523D0 (en) * | 2015-10-05 | 2015-11-18 | Ostara Biomedical Ltd | Methods and compositions for managing reproduction |
| SI3973982T1 (sl) | 2017-09-01 | 2024-10-30 | Ferring B. V. | Sestavek za nadzorovano stimulacijo jajčnikov |
| WO2019211153A1 (en) * | 2018-04-30 | 2019-11-07 | Ferring B.V. | Composition for controlled ovarian stimulation |
| CN108969755A (zh) * | 2018-07-17 | 2018-12-11 | 山东农业大学 | 一种控制驴排卵时间段相对集中的药物组合物及使用方法 |
| CN110787286B (zh) * | 2019-11-21 | 2024-06-25 | 重庆市畜牧科学院 | Fsh和hcg在制备促进睾丸细胞功能恢复的药物中的应用 |
| WO2025149590A1 (en) * | 2024-01-09 | 2025-07-17 | Ferring B.V. | Compositions and methods for controlled ovarian stimulation |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4923805A (en) | 1983-11-02 | 1990-05-08 | Integrated Genetics, Inc. | Fsh |
| US5635475A (en) * | 1987-12-21 | 1997-06-03 | Applied Research Systems Ars Holding N.V. | Site-directed mutagenesis modified glycoprotein hormones and methods of use |
| IE64738B1 (en) | 1990-03-20 | 1995-09-06 | Akzo Nv | Stabilized gonadotropin containing preparations |
| EP0695171B1 (en) * | 1993-04-28 | 1996-12-18 | Akzo Nobel N.V. | Lyospheres comprising gonadotropin |
| TW518235B (en) * | 1997-01-15 | 2003-01-21 | Akzo Nobel Nv | A gonadotropin-containing pharmaceutical composition with improved stability on prolong storage |
| CA2372714A1 (en) | 1999-05-07 | 2000-11-16 | Stephen Franks | The use of luteinizing hormone in the induction of pauci-or unifolliculogenesis |
| DE60238490D1 (de) | 2001-09-12 | 2011-01-13 | Merck Serono Sa | Verwendung von humanem choriongonadotropin (hcg) und luteinisierendem hormon (lh) zur regulierten hyperstimulation der eierstöcke |
| HRP20040087A2 (en) | 2001-09-12 | 2004-12-31 | Applied Research Systems | USE OF hCG IN CONTROLLED OVARIAN HYPERSTIMULATION |
| SI1434600T1 (sl) * | 2001-09-12 | 2009-06-30 | Serono Lab | Uporaba lh za kontrolirano hiperstimulacijo ovarijev |
| US6818613B2 (en) * | 2001-11-07 | 2004-11-16 | Ortho-Mcneil Pharmaceutical, Inc. | Aqueous sustained-release formulations of proteins |
| EP1364658A1 (en) * | 2002-05-24 | 2003-11-26 | Applied Research Systems ARS Holding N.V. | Use of varying ratios of gonadotrophins in controlled ovarian hyperstimulation |
| AU2003269904A1 (en) * | 2002-07-10 | 2004-01-23 | The Ohio State University Research Foundation | Antigen-polymer compositions |
| JP2006522151A (ja) | 2003-04-01 | 2006-09-28 | アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ | 不妊症におけるホスホジエステラーゼ阻害剤 |
| US20040248784A1 (en) * | 2003-06-03 | 2004-12-09 | Marco Filicori | Unitary combinations of FSH and hCG |
-
2003
- 2003-06-03 US US10/452,926 patent/US20040248784A1/en not_active Abandoned
-
2004
- 2004-06-02 US US10/559,610 patent/US7985732B2/en not_active Expired - Fee Related
- 2004-06-02 EP EP10075419.1A patent/EP2292252B1/en not_active Revoked
- 2004-06-02 CA CA002524755A patent/CA2524755A1/en not_active Abandoned
- 2004-06-02 JP JP2006508427A patent/JP2006526609A/ja active Pending
- 2004-06-02 BR BRPI0410968-6A patent/BRPI0410968A/pt not_active IP Right Cessation
- 2004-06-02 AU AU2004243256A patent/AU2004243256B2/en not_active Ceased
- 2004-06-02 WO PCT/IB2004/001813 patent/WO2004105788A1/en not_active Ceased
- 2004-06-02 NZ NZ543403A patent/NZ543403A/en unknown
- 2004-06-02 RU RU2005136527/15A patent/RU2332228C2/ru not_active IP Right Cessation
- 2004-06-02 ES ES10075419T patent/ES2753822T3/es not_active Expired - Lifetime
- 2004-06-02 ES ES04735774.4T patent/ES2451028T3/es not_active Expired - Lifetime
- 2004-06-02 KR KR1020077026953A patent/KR20070118195A/ko not_active Withdrawn
- 2004-06-02 CN CNA2007101527680A patent/CN101156945A/zh active Pending
- 2004-06-02 EP EP04735774.4A patent/EP1633389B1/en not_active Revoked
- 2004-06-02 KR KR1020057023048A patent/KR20060005417A/ko not_active Ceased
- 2004-06-02 MX MXPA05012967A patent/MXPA05012967A/es unknown
- 2004-06-02 CN CNA2004800153410A patent/CN1826135A/zh active Pending
-
2005
- 2005-12-02 ZA ZA200509814A patent/ZA200509814B/en unknown
-
2006
- 2006-01-02 NO NO20060002A patent/NO20060002L/no not_active Application Discontinuation
-
2007
- 2007-09-12 US US11/898,470 patent/US20080119394A1/en not_active Abandoned
- 2007-10-31 US US11/979,265 patent/US7964562B2/en not_active Expired - Fee Related
-
2011
- 2011-05-31 US US13/067,418 patent/US20120015879A1/en not_active Abandoned
-
2017
- 2017-04-18 US US15/490,058 patent/US20170281731A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ES2451028T3 (es) | 2014-03-26 |
| CN1826135A (zh) | 2006-08-30 |
| EP2292252A2 (en) | 2011-03-09 |
| RU2005136527A (ru) | 2006-07-27 |
| ZA200509814B (en) | 2007-01-31 |
| US20040248784A1 (en) | 2004-12-09 |
| NO20060002L (no) | 2006-03-02 |
| US7964562B2 (en) | 2011-06-21 |
| NZ543403A (en) | 2008-05-30 |
| US20120015879A1 (en) | 2012-01-19 |
| MXPA05012967A (es) | 2006-03-17 |
| WO2004105788A1 (en) | 2004-12-09 |
| JP2006526609A (ja) | 2006-11-24 |
| CA2524755A1 (en) | 2004-12-09 |
| US20170281731A1 (en) | 2017-10-05 |
| US7985732B2 (en) | 2011-07-26 |
| US20060135421A1 (en) | 2006-06-22 |
| AU2004243256A1 (en) | 2004-12-09 |
| EP1633389A1 (en) | 2006-03-15 |
| RU2332228C2 (ru) | 2008-08-27 |
| EP2292252A3 (en) | 2012-08-29 |
| EP1633389B1 (en) | 2013-12-11 |
| ES2753822T3 (es) | 2020-04-14 |
| EP2292252B1 (en) | 2019-08-07 |
| US20080119394A1 (en) | 2008-05-22 |
| US20080108571A1 (en) | 2008-05-08 |
| CN101156945A (zh) | 2008-04-09 |
| KR20060005417A (ko) | 2006-01-17 |
| AU2004243256B2 (en) | 2007-11-29 |
| KR20070118195A (ko) | 2007-12-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A, 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012. |