BRPI0411367A - composições oftálmicas contendo uma combinação sinergìstica de três polìmeros - Google Patents

composições oftálmicas contendo uma combinação sinergìstica de três polìmeros

Info

Publication number
BRPI0411367A
BRPI0411367A BRPI0411367-5A BRPI0411367A BRPI0411367A BR PI0411367 A BRPI0411367 A BR PI0411367A BR PI0411367 A BRPI0411367 A BR PI0411367A BR PI0411367 A BRPI0411367 A BR PI0411367A
Authority
BR
Brazil
Prior art keywords
polymers
combination
compositions containing
synergistically
ophthalmic compositions
Prior art date
Application number
BRPI0411367-5A
Other languages
English (en)
Inventor
Masood A Chowhan
Huagang Chen
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of BRPI0411367A publication Critical patent/BRPI0411367A/pt
Publication of BRPI0411367B1 publication Critical patent/BRPI0411367B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

"COMPOSIçõES OFTáLMICAS CONTENDO UMA COMBINAçãO SINERGìSTICA DE TRêS POLìMEROS". A presente invenção refere-se a composições oftálmicas adequadas para uso como lágrimas artificiais ou como veículos para fármacos oftálmicos. As composições contêm uma combinação de três polímeros que possuem um efeito sinergístico sobre a viscosidade.
BRPI0411367A 2003-06-13 2004-06-08 composições oftálmicas contendo uma combinação sinergística de três polímeros BRPI0411367B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47871303P 2003-06-13 2003-06-13
PCT/US2004/018067 WO2004112750A2 (en) 2003-06-13 2004-06-08 Ophthalmic compositions containing a synergistic combination of three polymers

Publications (2)

Publication Number Publication Date
BRPI0411367A true BRPI0411367A (pt) 2006-07-25
BRPI0411367B1 BRPI0411367B1 (pt) 2017-05-02

Family

ID=33539115

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0411367A BRPI0411367B1 (pt) 2003-06-13 2004-06-08 composições oftálmicas contendo uma combinação sinergística de três polímeros

Country Status (20)

Country Link
US (4) US7244440B2 (pt)
EP (1) EP1633324B1 (pt)
JP (2) JP4657213B2 (pt)
KR (1) KR101082345B1 (pt)
CN (1) CN100340233C (pt)
AR (1) AR047205A1 (pt)
AT (1) ATE348600T1 (pt)
AU (1) AU2004249136B2 (pt)
BR (1) BRPI0411367B1 (pt)
CA (1) CA2527417C (pt)
CY (1) CY1105877T1 (pt)
DE (1) DE602004003812T2 (pt)
DK (1) DK1633324T3 (pt)
ES (1) ES2274476T3 (pt)
MX (1) MXPA05013293A (pt)
PL (1) PL1633324T3 (pt)
PT (1) PT1633324E (pt)
TW (1) TWI336257B (pt)
WO (1) WO2004112750A2 (pt)
ZA (1) ZA200509441B (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2839847C (en) * 2003-06-13 2016-03-15 Masood A. Chowhan Ophthalmic compositions containing a synergistic combination of two polymers
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
US7947295B2 (en) * 2003-06-13 2011-05-24 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
ES2593113T3 (es) 2003-08-07 2016-12-05 Allergan, Inc. Composiciones para el suministro de agentes terapéuticos en los ojos y métodos para obtener y usar los mismos
KR20070024558A (ko) * 2004-05-27 2007-03-02 산텐 세이야꾸 가부시키가이샤 안과용 점조화제
WO2007076358A1 (en) * 2005-12-23 2007-07-05 Alcon, Inc. PHARMACEUTICAL FORMULATION FOR DELIVERY OF RECEPTOR TYROSINE KINASE INHIBITING (RTKi) COMPOUNDS TO THE EYE
FR2896152B1 (fr) * 2006-01-17 2016-01-08 Cetem Lab Nouvelles compositions cosmetiques et leur utilisation pour l'application sur les muqueuses
KR20090053892A (ko) 2006-07-25 2009-05-28 오스모티카 코프. 점안액
US20080057022A1 (en) * 2006-08-30 2008-03-06 Erning Xia Ophthalmic Pharmaceutical Compositions and Uses Thereof
MX2009007774A (es) 2007-02-09 2009-07-31 Alcon Inc Composiciones oftalmicas que contienen una combinacion sinergistica de tres polimeros.
AU2008285388B2 (en) 2007-08-08 2013-09-19 Lexicon Pharmaceuticals, Inc. (7h-pyrrolo [2, 3-d] pyrimidin-4-yl) -piperazines as kinase inhibitors for the treatment of cancer and inflammation
US9192571B2 (en) 2008-03-03 2015-11-24 Allergan, Inc. Ketorolac tromethamine compositions for treating or preventing ocular pain
MX2010009857A (es) * 2008-03-07 2010-12-07 Sun Pharma Advanced Res Co Ltd Composicion oftalmica.
US8193202B2 (en) 2008-04-21 2012-06-05 Lexicon Pharmaceuticals, Inc. LIMK2 inhibitors, compositions comprising them, and methods of their use
NZ589323A (en) * 2008-04-26 2012-04-27 Alcon Res Ltd Polymeric artificial tear system
US20110293549A1 (en) 2009-02-03 2011-12-01 Athena Cosmetics, Inc. Composition, method and kit for enhancing hair
TWI547522B (zh) * 2009-07-07 2016-09-01 愛爾康研究有限公司 環氧乙烷環氧丁烷嵌段共聚物組成物
PL2506831T3 (pl) 2009-12-03 2014-05-30 Alcon Res Ltd Zawiesiny zawierające nanocząsteczkowe polimery karbowinylowe
AU2011207280A1 (en) 2010-01-22 2012-07-19 Lexicon Pharmaceuticals, Inc. 5-(1h-pyrazol-5-yl)thiazole-based compounds for the treatment of diseases and disorders of the eye
DE102010009475B4 (de) 2010-02-26 2011-11-24 F. Holzer Gmbh Verfahren zur Herstellung eines dosierbaren applikationsfertigen Präparates
KR20130060228A (ko) * 2010-05-05 2013-06-07 알콘 리서치, 리미티드 안정화된 안과용 갈락토만난 제제
PT2787969T (pt) * 2011-12-07 2021-11-09 Allergan Inc Entrega eficiente de lípidos para o filme lacrimal humano utilizando um sistema de emulsão sensível ao sal
FR2988297B1 (fr) * 2012-03-22 2014-03-28 Thea Lab Solution ophtalmique aqueuse a base de ciclosporine a sans conservateur
TWI658828B (zh) * 2014-10-31 2019-05-11 中國醫藥大學 用於舒緩及減輕近視之醫藥組合物及其製備方法與用途
CN113518646B (zh) * 2019-02-27 2023-12-12 参天制药株式会社 含有地夸磷索或其盐，乙烯基系高分子及纤维素系高分子的眼科用组合物

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3355336A (en) * 1966-08-18 1967-11-28 Du Pont Thickened water-bearing inorganic oxidizer salt explosive containing crosslinked galactomannan and polyacrylamide
NL188266C (nl) * 1975-07-29 1992-05-18 Merck & Co Inc Werkwijze ter bereiding van een oogheelkundig inplantaat.
US4039662A (en) * 1975-12-04 1977-08-02 Alcon Laboratories, Inc. Ophthalmic solution
US4136173A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
US4767463A (en) * 1987-04-15 1988-08-30 Union Carbide Corporation Glycosaminoglycan and cationic polymer combinations
US5188826A (en) * 1988-02-08 1993-02-23 Insite Vision Incorporated Topical ophthalmic suspensions
US5368843A (en) * 1988-06-08 1994-11-29 Lever Brothers Company, Division Of Conopco, Inc. Thickening system
US5075104A (en) * 1989-03-31 1991-12-24 Alcon Laboratories, Inc. Ophthalmic carboxy vinyl polymer gel for dry eye syndrome
US5252318A (en) 1990-06-15 1993-10-12 Allergan, Inc. Reversible gelation compositions and methods of use
US5460834A (en) * 1991-12-13 1995-10-24 Alcon Laboratories, Inc. Combinations of polymers for use in physiological tear compositions
WO1993017664A1 (en) * 1992-03-02 1993-09-16 Alcon Laboratories, Inc. Combinations of cellulosic polymers and carboxy vinyl polymers and their use in pharmaceutical compositions
CA2134376C (en) * 1993-12-20 2001-10-23 Haresh G. Bhagat Combinations of polymers for use in physiological tear compositions
DE69502539T2 (de) * 1994-03-18 1998-10-01 Senju Pharma Co Sarpogrelat enthaltende opthalmologische Zubereitungen zur Senkung des intraokularen Druckes
US5939485A (en) * 1995-06-19 1999-08-17 Medlogic Global Corporation Responsive polymer networks and methods of their use
ATE391492T1 (de) * 1997-07-29 2008-04-15 Alcon Lab Inc Ophthalmische zusammensetzungen enthaltend galaktomannanpolymere und borat
AU725552B2 (en) * 1997-07-29 2000-10-12 Alcon Laboratories, Inc. Conditioning solutions for hard contact lens care
JP2000159659A (ja) * 1998-11-30 2000-06-13 Kazuo Tsubota 眼科用人工涙液
AR035509A1 (es) * 2000-12-21 2004-06-02 Alcon Inc Solucion de lagrimas artificiales mejorada que contiene una combinacion de tres emolientes y el uso de dicha solucion para la fabricacion de un medicamento
US7001615B1 (en) * 2001-12-07 2006-02-21 Alcon, Inc. Sustained release ophthalmic, otic and nasal suspension
AU2002360752A1 (en) 2001-12-21 2003-07-30 Alcon, Inc. Viscoelastics for ocular surgery
WO2003072081A1 (en) * 2002-02-22 2003-09-04 Pharmacia Corporation Ophthalmic formulation with gum system
US20050013854A1 (en) * 2003-04-09 2005-01-20 Mannino Raphael J. Novel encochleation methods, cochleates and methods of use
CA2839847C (en) 2003-06-13 2016-03-15 Masood A. Chowhan Ophthalmic compositions containing a synergistic combination of two polymers
US7947295B2 (en) 2003-06-13 2011-05-24 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
US7914803B2 (en) 2003-06-13 2011-03-29 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of three polymers

Also Published As

Publication number Publication date
AU2004249136A1 (en) 2004-12-29
CA2527417A1 (en) 2004-12-29
MXPA05013293A (es) 2006-03-09
US7618620B2 (en) 2009-11-17
US20070224159A1 (en) 2007-09-27
AU2004249136B2 (en) 2009-09-03
AR047205A1 (es) 2006-01-11
KR20060012023A (ko) 2006-02-06
PL1633324T3 (pl) 2007-03-30
JP4657213B2 (ja) 2011-03-23
US20070231294A1 (en) 2007-10-04
PT1633324E (pt) 2007-01-31
BRPI0411367B1 (pt) 2017-05-02
CA2527417C (en) 2013-12-03
ATE348600T1 (de) 2007-01-15
TWI336257B (en) 2011-01-21
EP1633324B1 (en) 2006-12-20
DE602004003812D1 (de) 2007-02-01
JP2006528990A (ja) 2006-12-28
CN1802148A (zh) 2006-07-12
US7244440B2 (en) 2007-07-17
US20080075687A1 (en) 2008-03-27
EP1633324A2 (en) 2006-03-15
WO2004112750A3 (en) 2005-08-18
US20040253202A1 (en) 2004-12-16
US7306802B2 (en) 2007-12-11
JP2011026355A (ja) 2011-02-10
JP5161950B2 (ja) 2013-03-13
WO2004112750A2 (en) 2004-12-29
DE602004003812T2 (de) 2007-04-26
US7329411B2 (en) 2008-02-12
DK1633324T3 (da) 2007-04-02
ES2274476T3 (es) 2007-05-16
ZA200509441B (en) 2007-03-28
TW200501969A (en) 2005-01-16
KR101082345B1 (ko) 2011-11-10
CY1105877T1 (el) 2011-02-02
CN100340233C (zh) 2007-10-03

Similar Documents

Publication Publication Date Title
BRPI0411367A (pt) composições oftálmicas contendo uma combinação sinergìstica de três polìmeros
BRPI0411361A (pt) composições oftálmicas contendo uma combinação sinérgica de dois polìmeros
MX2009007774A (es) Composiciones oftalmicas que contienen una combinacion sinergistica de tres polimeros.
BRPI0411528A (pt) uso de isomalte como prebiótico
CR8858A (es) Derivados de sulfamato y sulfamida para el tratamiento de epilepsia y trastornos relacionados
ECSP077275A (es) Novedosos derivados de heteroarilsulfamida benzofusionados utiles como agentes anticonvulsivos
ECSP066391A (es) [1,8] naftiridin-2-onas y compuestos relacionados para el tratamiento de la esquizofrenia
UY28215A1 (es) Quinazolinas utiles como moduladores de canales iónicos
ES2150050T3 (es) Polisacaridos injertados con antioxidantes y su utilizacion.
NI201000055A (es) 2' - fluoro - 2' - desoxitetrahidrouridinas como inhibidores de citidina desaminasa.
ECSP045004A (es) Inhibidores de la 17beta-hidroxiesteroide deshidrogenasa tipo 3 para el tratamiento de enfermedades andrógeno dependientes
ECSP088763A (es) Nuevas combinaciones terapéuticas para el tratamiento de la depresión
BRPI0806863B8 (pt) uso de um éster de forbol na preparação de um medicamento para prevenção ou tratamento de uma infecção por hiv
ECSP099776A (es) Moduladores de la gamma secretasa
CR9114A (es) 2-alcoxi-3,4,5-trihydroxi-alquimidas, su preparacion composicones que las contienen y su utilizacion
BRPI0413742A (pt) derivados de mitoquinona usados como antioxidantes mitocondrialmente alvejados
BR0314352A (pt) Indóis 2,7-substituìdos e seu uso como moduladores de 5-ht6
GT200600161A (es) Nuevas combinaciones terapeuticas para el tratamiento o la prevencion de los trastornos psicoticos
CR7956A (es) Oxazolidinonas de indolona antibacterial intermedios para su preparacion y composiciones farmaceuticas que contienen los mismos
ATE554753T1 (de) 2,2'-dithio-bis(ethansulfonat) für den einsatz zur hemmung paclitaxel-induzierter abnormer thermoesthesia
AR043253A1 (es) 4-[(2,4-dicloro-5-metoxifenil)amino] -6- alcoxi-3-quinolina carbonitrilos para el tratamiento de lesiones isquemicas
CL2008001559A1 (es) Compuestos heterociclos que contienen al menos un atomo de nitrogeno, moduladores de gamma secretasa; composiciones farmaceuticas que los comprenden; uso de los compuestos en la preparacion de medicamentos para tratar trastornos del sistema nervioso central, tal como alzheimer; y kit que incluye a la composicion farmaceutica.
BR112014012885A2 (pt) composição de gel celulósica com estabilidade de viscosidade aperfeiçoada
GT200500340A (es) Derivados de octahidropirrolo [3,4-c] pirrol
BR0101449A (pt) Composição antioxidante e composição cosmética ou farmacêutica

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 14A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)