BRPI0411784A - anticorpos contra interleucina -22 e usos para os mesmos - Google Patents

anticorpos contra interleucina -22 e usos para os mesmos

Info

Publication number
BRPI0411784A
BRPI0411784A BRPI0411784-0A BRPI0411784A BRPI0411784A BR PI0411784 A BRPI0411784 A BR PI0411784A BR PI0411784 A BRPI0411784 A BR PI0411784A BR PI0411784 A BRPI0411784 A BR PI0411784A
Authority
BR
Brazil
Prior art keywords
antibodies
interleukin
disclosed
associated immune
disorders
Prior art date
Application number
BRPI0411784-0A
Other languages
English (en)
Inventor
Jing Li
Xiang-Yang Tan
Kathleen N Tomkinson
Debra D Pittman
Geertruida M Veldman
Lynette Fouser
Original Assignee
Genetics Inst Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst Llc filed Critical Genetics Inst Llc
Publication of BRPI0411784A publication Critical patent/BRPI0411784A/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
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    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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Abstract

"ANTICORPOS CONTRA INTERLEUCINA -22 E USOS PARA OS MESMOS". Anticorpos e seus fragmentos de ligação a antígeno que ligam-se a interleucina-22 (IL-22), em particular, IL-22 humana, e seus usos em regulação de respostas imunes associadas com IL-22 são mostrados. Os anticorpos aqui mostrados são úteis em diagnóstico, prevenção, ao tratamento de doenças imunes associadas com IL-22, por exemplo, doenças autoimune (por exemplo, artrite).
BRPI0411784-0A 2003-06-23 2004-06-22 anticorpos contra interleucina -22 e usos para os mesmos BRPI0411784A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48065203P 2003-06-23 2003-06-23
PCT/US2004/020833 WO2005000897A2 (en) 2003-06-23 2004-06-22 Antibodies against interleukin-22 and uses therefor

Publications (1)

Publication Number Publication Date
BRPI0411784A true BRPI0411784A (pt) 2006-08-08

Family

ID=33551931

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0411784-0A BRPI0411784A (pt) 2003-06-23 2004-06-22 anticorpos contra interleucina -22 e usos para os mesmos

Country Status (19)

Country Link
EP (1) EP1644415B1 (pt)
JP (2) JP2007537132A (pt)
KR (1) KR20060022289A (pt)
CN (1) CN1839157A (pt)
AT (1) ATE490275T1 (pt)
AU (1) AU2004252169A1 (pt)
BR (1) BRPI0411784A (pt)
CA (1) CA2530386A1 (pt)
CR (1) CR8211A (pt)
DE (1) DE602004030341D1 (pt)
EC (1) ECSP066297A (pt)
ES (1) ES2354693T3 (pt)
IL (1) IL172646A0 (pt)
MX (1) MXPA05013881A (pt)
NI (1) NI200500230A (pt)
NO (1) NO20060189L (pt)
RU (1) RU2006101702A (pt)
WO (1) WO2005000897A2 (pt)
ZA (1) ZA200600608B (pt)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7771719B1 (en) 2000-01-11 2010-08-10 Genentech, Inc. Pharmaceutical compositions, kits, and therapeutic uses of antagonist antibodies to IL-17E
NZ508878A (en) 1998-05-15 2003-08-29 Genentech Inc IL-17B and IL-17Cactive variants of IL-17 which stimulates epithelial, endothelial and fibroblastic cells
US7718397B2 (en) 2000-03-21 2010-05-18 Genentech, Inc. Nucleic acids encoding receptor for IL-17 homologous polypeptides and uses thereof
US20030096969A1 (en) 2000-06-02 2003-05-22 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
DE10303974A1 (de) 2003-01-31 2004-08-05 Abbott Gmbh & Co. Kg Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
PL2784084T5 (pl) 2003-07-08 2024-12-02 Novartis Pharma Ag Przeciwciała antagonistyczne heterologicznych polipeptydów il-17a/f
US20070269428A1 (en) 2003-11-21 2007-11-22 Celltech R&D Limited Method for the Treatment of Multiple Sclerosis by Inhibiting Il-17 Activity
ES2534760T3 (es) 2005-08-19 2015-04-28 Wyeth Llc Anticuerpos antagonistas contra GDF-8 y sus usos en el tratamiento de ELA y otros trastornos asociados con GDF-8
PL2289909T3 (pl) 2005-11-30 2015-04-30 Abbvie Inc Sposób przeszukiwania, proces oczyszczania niedyfundujących oligomerów Abeta, selektywne przeciwciała przeciw niedyfundującym oligomerom Abeta i sposób wytwarzania tych przeciwciał
RU2432362C2 (ru) 2005-11-30 2011-10-27 Эбботт Лэборетриз Моноклональные антитела и их применения
EP1954719A2 (en) * 2005-12-02 2008-08-13 Genentech Inc. Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling involving antibodies that bind to il-22 and il-22r
AU2013200914B2 (en) * 2005-12-02 2016-01-14 Genentech, Inc. Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling involving antibodies that bind to IL-22 and IL-22R
WO2007095643A2 (en) * 2006-02-16 2007-08-23 Nascent Biologics, Inc. Methods for improving immune function and methods for prevention or treatment of disease in a mammalian subject
TWI417301B (zh) 2006-02-21 2013-12-01 Wyeth Corp 對抗人類介白素-２２（ｉｌ-２２）之抗體及其用途
TW200744634A (en) * 2006-02-21 2007-12-16 Wyeth Corp Methods of using antibodies against human IL-22
CA2652924A1 (en) * 2006-06-19 2007-12-27 Wyeth Methods of modulating il-22 and il-17
US8455626B2 (en) 2006-11-30 2013-06-04 Abbott Laboratories Aβ conformer selective anti-aβ globulomer monoclonal antibodies
EP2124952A2 (en) 2007-02-27 2009-12-02 Abbott GmbH & Co. KG Method for the treatment of amyloidoses
US20100247547A1 (en) * 2007-05-29 2010-09-30 Chen Dong Modulation of the th-17 cell mediated immune responses
CN101225110B (zh) * 2007-10-23 2010-10-20 中国人民解放军军事医学科学院基础医学研究所 人白细胞介素-22突变体及其构建方法和应用
WO2009062102A2 (en) * 2007-11-07 2009-05-14 Genentech, Inc. Compositions and methods for treatment of microbial disorders
CA2718634A1 (en) * 2008-03-21 2009-09-24 Wyeth Llc Antibodies against interleukin-10-like cytokines and uses therefor
SG10201608871XA (en) 2008-05-05 2016-12-29 Novimmune Sa Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof
CA2759848C (en) 2009-05-05 2018-12-04 Novimmune S.A. Anti-il-17f antibodies and methods of use thereof
ES2684475T3 (es) 2010-04-15 2018-10-03 Abbvie Inc. Proteínas que se unen a beta amiloide
CN103298833B (zh) 2010-08-14 2015-12-16 Abbvie公司 β淀粉样蛋白结合蛋白
JP2014517279A (ja) 2011-05-10 2014-07-17 ネステク ソシエテ アノニム 個別治療管理のための疾患活動性プロファイリングの方法
EP3385277A1 (en) 2013-03-15 2018-10-10 F. Hoffmann-La Roche AG Il-22 polypeptides and il-22 fc fusion proteins and methods of use
US20190317098A1 (en) * 2016-11-24 2019-10-17 Huvet Bio, Inc. Composition for diagnosis of diseases
US20180251522A1 (en) * 2017-02-21 2018-09-06 The Regents Of The University Of Michigan Il-22bp compositions and method for the treatment of disease therewith
AU2018277256A1 (en) 2017-05-31 2020-01-30 Prometheus Biosciences, Inc. Methods for assessing mucosal healing in Crohn's disease patients
KR102536314B1 (ko) * 2018-05-23 2023-05-25 주식회사 휴벳바이오 질환의 진단용 조성물
US11834472B2 (en) 2018-06-05 2023-12-05 Bioatla, Inc. Anti-IL-22 antibodies, antibody fragments, their immunoconjugates and uses thereof
KR20210110294A (ko) * 2018-11-07 2021-09-07 어플라이드 몰레큘라 트랜스포트 인크. 통과세포외배출용 전달 구조체 및 관련 방법
US20230416357A1 (en) 2020-12-07 2023-12-28 UCB Biopharma SRL Antibodies against interleukin-22

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002016611A2 (en) * 2000-08-24 2002-02-28 Genentech, Inc. Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
US6939545B2 (en) * 1999-04-28 2005-09-06 Genetics Institute, Llc Composition and method for treating inflammatory disorders
US20030170823A1 (en) * 1999-12-23 2003-09-11 Presnell Scott R. Novel cytokine ZCYTO18
DE60129137D1 (de) * 2000-07-27 2007-08-09 Wyeth Corp Modulierung durch il-tif/interleukin-21
MXPA03007413A (es) * 2001-02-23 2003-11-18 Inst Genetics Llc Composicion y metodo para tratar enfermedades inflamatorias.

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EP1644415A2 (en) 2006-04-12
WO2005000897A3 (en) 2005-03-31
CN1839157A (zh) 2006-09-27
CA2530386A1 (en) 2005-01-06
NO20060189L (no) 2006-03-20
ZA200600608B (en) 2007-05-30
RU2006101702A (ru) 2006-09-10
ES2354693T3 (es) 2011-03-17
DE602004030341D1 (de) 2011-01-13
EP1644415B1 (en) 2010-12-01
CR8211A (es) 2006-04-27
NI200500230A (es) 2008-01-30
KR20060022289A (ko) 2006-03-09
IL172646A0 (en) 2006-04-10
AU2004252169A1 (en) 2005-01-06
MXPA05013881A (es) 2008-02-13
WO2005000897A2 (en) 2005-01-06
ATE490275T1 (de) 2010-12-15

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