BRPI0412438A - novas amidas aza-heterocìclicas úteis para o tratamento da dor - Google Patents

novas amidas aza-heterocìclicas úteis para o tratamento da dor

Info

Publication number
BRPI0412438A
BRPI0412438A BRPI0412438-3A BRPI0412438A BRPI0412438A BR PI0412438 A BRPI0412438 A BR PI0412438A BR PI0412438 A BRPI0412438 A BR PI0412438A BR PI0412438 A BRPI0412438 A BR PI0412438A
Authority
BR
Brazil
Prior art keywords
new
azaheterocyclic
pain treatment
amides useful
compounds
Prior art date
Application number
BRPI0412438-3A
Other languages
English (en)
Inventor
Guo Zhu Zheng
Brian S Brown
Sean C Turner
Tammie K White
Robert G Schmidt
John R Koenig
Chih-Hung Lee
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of BRPI0412438A publication Critical patent/BRPI0412438A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

"NOVAS AMIDAS AZA-HETEROCìCLICAS úTEIS PARA O TRATAMENTO DA DOR". A presente invenção está relacionada a compostos de fórmula (I-VII), ou um seu sal ou prodroga farmaceuticamente aceitável, nos quais A, L, R~ 6~, R~ 7~ e R~ 8~ são aqui definidos. A presente invenção também está relacionada a metodos para tratar dor utilizando esses compostos e composições farmacêuticas que incluem esses compostos.
BRPI0412438-3A 2003-07-11 2004-07-09 novas amidas aza-heterocìclicas úteis para o tratamento da dor BRPI0412438A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/618,016 US20050009841A1 (en) 2003-07-11 2003-07-11 Novel amides useful for treating pain
PCT/US2004/021836 WO2005007642A2 (en) 2003-07-11 2004-07-09 Novel azaheterocyclic amides useful for treating pain

Publications (1)

Publication Number Publication Date
BRPI0412438A true BRPI0412438A (pt) 2006-09-05

Family

ID=33565052

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0412438-3A BRPI0412438A (pt) 2003-07-11 2004-07-09 novas amidas aza-heterocìclicas úteis para o tratamento da dor

Country Status (13)

Country Link
US (1) US20050009841A1 (pt)
EP (1) EP1646621A2 (pt)
JP (1) JP2007523865A (pt)
KR (1) KR20060034282A (pt)
CN (2) CN101434596A (pt)
AU (1) AU2004257220A1 (pt)
BR (1) BRPI0412438A (pt)
CA (1) CA2532057A1 (pt)
IL (1) IL172985A0 (pt)
MX (1) MXPA06000416A (pt)
TW (1) TW200510372A (pt)
WO (1) WO2005007642A2 (pt)
ZA (1) ZA200600228B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1627869B1 (en) * 2003-05-20 2012-05-02 Ajinomoto Co., Inc. Vanilloid receptor modulators
TWI287010B (en) * 2003-06-12 2007-09-21 Euro Celtique Sa Therapeutic agents useful for treating pain
DE602004017316D1 (de) 2003-07-24 2008-12-04 Euro Celtique Sa Heteroaryl-tetrahydropyridylverbindungen, die sich für die behandlung bzw. die prävention von schmerzen eignen
GEP20094676B (en) 2003-07-24 2009-05-10 Euro Celtique Sa Piperidine compounds and pharmaceutical compositions containing them
WO2005012287A1 (en) 2003-08-01 2005-02-10 Euro-Celtique S.A. Therapeutic agents useful for treating pain
CA2685266C (en) * 2007-04-27 2014-01-28 Purdue Pharma L.P. Trpv1 antagonists and uses thereof for the treatment of prevention of pain, ui and ulcer, ibd, or ibs in an animal
MX2009011601A (es) * 2007-04-27 2009-11-10 Purdue Pharma Lp Agentes terapeuticos utiles para tratar el dolor.
PE20141531A1 (es) 2011-06-22 2014-10-23 Purdue Pharma Lp Antagonistas de trpv1 que incluyen sustituyentes dihidroxi y sus usos
WO2013146970A1 (ja) * 2012-03-29 2013-10-03 第一三共株式会社 新規キノリン誘導体
TWI652264B (zh) * 2013-09-26 2019-03-01 東麗股份有限公司 Cyclic amine derivatives and their medical uses
DE102022104759A1 (de) 2022-02-28 2023-08-31 SCi Kontor GmbH Co-Kristall-Screening Verfahren, insbesondere zur Herstellung von Co-Kristallen

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2579596B1 (fr) * 1985-03-26 1987-11-20 Inst Nat Sante Rech Med (imidazolyl-4) piperidines, leur preparation et leur application en therapeutique
EP1086078B1 (en) * 1998-06-08 2003-02-05 Schering Corporation Neuropeptide y5 receptor antagonists
EP1301484A2 (en) * 2000-07-20 2003-04-16 Neurogen Corporation Capsaicin receptor ligands
US20040259912A1 (en) * 2001-09-28 2004-12-23 Takahiro Matsumoto Benzine derivatives, process for preparing the same and use thereof
JP2003192673A (ja) * 2001-12-27 2003-07-09 Bayer Ag ピペラジンカルボキシアミド誘導体
US7071335B2 (en) * 2002-02-01 2006-07-04 Euro-Celtique S.A. 2-pyridinyl-1-piperazine therapeutic agents useful for treating pain
US6974818B2 (en) * 2002-03-01 2005-12-13 Euro-Celtique S.A. 1,2,5-thiadiazol-3-YL-piperazine therapeutic agents useful for treating pain
US7262194B2 (en) * 2002-07-26 2007-08-28 Euro-Celtique S.A. Therapeutic agents useful for treating pain
EP1627869B1 (en) * 2003-05-20 2012-05-02 Ajinomoto Co., Inc. Vanilloid receptor modulators
TWI287010B (en) * 2003-06-12 2007-09-21 Euro Celtique Sa Therapeutic agents useful for treating pain

Also Published As

Publication number Publication date
AU2004257220A1 (en) 2005-01-27
MXPA06000416A (es) 2006-04-05
CN101434596A (zh) 2009-05-20
KR20060034282A (ko) 2006-04-21
TW200510372A (en) 2005-03-16
CN1849315A (zh) 2006-10-18
WO2005007642A3 (en) 2005-05-26
EP1646621A2 (en) 2006-04-19
US20050009841A1 (en) 2005-01-13
JP2007523865A (ja) 2007-08-23
CA2532057A1 (en) 2005-01-27
WO2005007642A2 (en) 2005-01-27
ZA200600228B (en) 2007-04-25
IL172985A0 (en) 2006-06-11

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B11E Dismissal acc. art. 34 of ipl - requirements for examination incomplete
B11T Dismissal of application maintained [chapter 11.20 patent gazette]