BRPI0412557A - forma de dosagem farmacêutica de eventos cardiovasculares - Google Patents
forma de dosagem farmacêutica de eventos cardiovascularesInfo
- Publication number
- BRPI0412557A BRPI0412557A BRPI0412557-6A BRPI0412557A BRPI0412557A BR PI0412557 A BRPI0412557 A BR PI0412557A BR PI0412557 A BRPI0412557 A BR PI0412557A BR PI0412557 A BRPI0412557 A BR PI0412557A
- Authority
- BR
- Brazil
- Prior art keywords
- dosage form
- pharmaceutical dosage
- cardiovascular events
- renin
- diuretic
- Prior art date
Links
- 239000002552 dosage form Substances 0.000 title abstract 3
- 230000007211 cardiovascular event Effects 0.000 title abstract 2
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 abstract 1
- 229960001138 acetylsalicylic acid Drugs 0.000 abstract 1
- 239000000674 adrenergic antagonist Substances 0.000 abstract 1
- 239000003529 anticholesteremic agent Substances 0.000 abstract 1
- 229940127226 anticholesterol agent Drugs 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"FORMA DE DOSAGEM FARMACêUTICA DE EVENTOS CARDIOVASCULARES". A forma de dosagem farmacêutica para o tratamento ou prevenção de eventos cardiovasculares compreende quantidade terapêutica de: um receptor antagonista <225>-adrenérgico, um diurético, ou ambos; um agente de redução de colesterol; um inibidor do sistema renina-angiotensina e aspirina.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN604CH2003 IN206994B (pt) | 2000-10-25 | 2001-10-25 | |
| PCT/US2004/024324 WO2005011586A2 (en) | 2003-07-28 | 2004-07-28 | Treatment and preventi0n of cardiovascular events |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0412557A true BRPI0412557A (pt) | 2006-09-19 |
Family
ID=34090476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0412557-6A BRPI0412557A (pt) | 2003-07-28 | 2004-07-28 | forma de dosagem farmacêutica de eventos cardiovasculares |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20050026992A1 (pt) |
| EP (1) | EP1648422A4 (pt) |
| CN (1) | CN1822820A (pt) |
| AU (1) | AU2004261212B2 (pt) |
| BR (1) | BRPI0412557A (pt) |
| CA (1) | CA2531279A1 (pt) |
| NZ (1) | NZ544784A (pt) |
| RU (1) | RU2380093C2 (pt) |
| WO (1) | WO2005011586A2 (pt) |
| ZA (1) | ZA200600733B (pt) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1648422A4 (en) * | 2003-07-28 | 2007-09-19 | Reddys Lab Inc Dr | TREATMENT AND PREVENTION OF CARDIOVASCULAR ACCIDENTS |
| US20090117197A1 (en) * | 2005-03-21 | 2009-05-07 | Vicus Therapeutics Llc | Compositions and methods for ameliorating cachexia |
| EP1990049A3 (en) * | 2005-03-21 | 2008-11-26 | Vicus Therapeutics SPE 1, LLC | Combination therapy of beta-blockers and non-steroidal anti-inflammatory drugs (NSAID) |
| US20070009591A1 (en) * | 2005-07-07 | 2007-01-11 | Trivedi Jay S | ACE inhibitor formulation |
| WO2007020079A2 (en) * | 2005-08-17 | 2007-02-22 | Synthon B.V. | Orally disintegratable simvastatin tablets |
| WO2007049291A1 (en) * | 2005-10-27 | 2007-05-03 | Lupin Limited | Novel solid dosage forms of valsartan and rochlorothiazide |
| WO2007058660A1 (en) * | 2005-11-18 | 2007-05-24 | Accu-Break Technologies, Inc. | Segmented pharmaceutical dosage forms |
| US20070116756A1 (en) * | 2005-11-23 | 2007-05-24 | Dr. Reddy's Laboratories Limited | Stable pharmaceutical compositions |
| US20070185065A1 (en) * | 2006-02-03 | 2007-08-09 | Vikramjit Chhokar | Combination therapy for coronary artery disease |
| ES2300188B1 (es) * | 2006-05-24 | 2009-05-01 | Ferrer Internacional, S.A. | Comprimido bicapa para la prevencion de los accidentes cardiovasculares. |
| WO2008001184A2 (en) * | 2006-06-26 | 2008-01-03 | Emcure Pharmaceuticals Limited | Solid composition |
| US20080107726A1 (en) * | 2006-11-01 | 2008-05-08 | Pramod Kharwade | Compositions comprising beta-adrenergic receptor antagonists and diuretics |
| MX2010010479A (es) * | 2008-03-28 | 2011-02-22 | Ferrer Int | Capsula para la prevencion de enfermedades cardiovasculares. |
| CN101590239B (zh) * | 2008-05-30 | 2013-03-27 | 北京奥萨医药研究中心有限公司 | 含有利尿剂、他汀和叶酸的药物组合物及其用途 |
| US9789187B2 (en) | 2009-02-11 | 2017-10-17 | Cadila Pharmaceuticals Limited | Stable pharmaceutical composition for atherosclerosis |
| MX357919B (es) * | 2009-03-13 | 2018-07-25 | Nucitec Sa De Cv | Composición farmacéutica para el tratamiento de la hipercolesterolemia. |
| AU2010242938A1 (en) * | 2009-04-30 | 2011-11-17 | Dr. Reddy's Laboratories Ltd. | Fixed dose drug combination formulations |
| CN101897710A (zh) * | 2009-05-27 | 2010-12-01 | 北京奥萨医药研究中心有限公司 | 含有HMG-CoA还原酶抑制剂、阿司匹林、叶酸的药物组合物及其用途 |
| MX2013000824A (es) * | 2010-07-21 | 2013-10-28 | Nucitec Sa De Cv | Forma de dosificacion diaria unica para la prevencion y tratamiento del sindrome metabolico. |
| GB201116993D0 (en) * | 2011-10-03 | 2011-11-16 | Ems Sa | Pharmaceutical compositions of antihypertensives |
| CN102357084B (zh) * | 2011-10-11 | 2014-02-26 | 广东彼迪药业有限公司 | 一种马来酸依那普利的片剂组合物及其制备与应用 |
| RU2491070C2 (ru) * | 2011-10-11 | 2013-08-27 | Общество с ограниченной ответственностью "Фармамед" | Фармацевтическая композиция для профилактики и лечения сердечно-сосудистых заболеваний |
| CN102671198A (zh) * | 2011-12-17 | 2012-09-19 | 东莞达信生物技术有限公司 | 一种降压降脂复方药及其制备方法 |
| EP2810644A1 (en) * | 2013-06-06 | 2014-12-10 | Ferrer Internacional, S.A. | Oral formulation for the treatment of cardiovascular diseases |
| KR20150079373A (ko) | 2013-12-30 | 2015-07-08 | 한미약품 주식회사 | 에제티미브 및 로수바스타틴을 포함하는 경구용 복합제제 |
| PH12018502155B1 (en) * | 2016-04-20 | 2024-03-27 | Servier Lab | Pharmaceutical composition comprising a beta blocker, a converting enzyme inhibitor and an antihypertensive or an nsaid |
| CN107184952A (zh) * | 2017-06-13 | 2017-09-22 | 江苏黄河药业股份有限公司 | 一种赖诺普利复方制剂及其制备方法 |
| CN110237258A (zh) * | 2018-03-09 | 2019-09-17 | 深圳奥萨制药有限公司 | 用于治疗高血压的药物组合物 |
| AU2019441241B2 (en) | 2019-04-17 | 2023-11-23 | CardioPharma, Inc. | Anti-hypertensive and cholesterol-lowering fixed-dose combination and method of manufacture |
| WO2021202457A1 (en) * | 2020-03-30 | 2021-10-07 | Exagen Inc. | Cardiovascular biomarkers for systemic lupus erythematosus |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5622985A (en) | 1990-06-11 | 1997-04-22 | Bristol-Myers Squibb Company | Method for preventing a second heart attack employing an HMG CoA reductase inhibitor |
| US6251852B1 (en) * | 1996-09-18 | 2001-06-26 | Merck & Co., Inc. | Combination therapy for reducing the risks associated with cardiovascular disease |
| US6235311B1 (en) * | 1998-03-18 | 2001-05-22 | Bristol-Myers Squibb Company | Pharmaceutical composition containing a combination of a statin and aspirin and method |
| US6121249A (en) * | 1998-07-01 | 2000-09-19 | Donald L. Weissman | Treatment and prevention of cardiovascular diseases with help of aspirin, antioxidants, niacin, and certain B vitamins |
| US6323188B1 (en) * | 1998-07-01 | 2001-11-27 | Donald L. Weissman | Treatment and prevention of cardiovascular diseases, heart attack, and stroke, primary and subsequent, with help of aspirin and certain vitamins |
| SK2692002A3 (en) * | 1999-08-30 | 2002-07-02 | Aventis Pharma Gmbh | Use of inhibitors of the renin-angiotensin system in the prevention of cardiovascular events |
| GB2361185A (en) * | 2000-04-10 | 2001-10-17 | Nicholas J Wald | Pharmaceutical formulation for the prevention of cardiovascular disease |
| DE60119715T3 (de) | 2000-04-10 | 2016-12-08 | Nicholas John Wald | Zusammensetzung zur prävention kardiovaskulärer erkrankungen |
| US6669955B2 (en) * | 2001-08-28 | 2003-12-30 | Longwood Pharmaceutical Research, Inc. | Combination dosage form containing individual dosage units of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin |
| US6576256B2 (en) * | 2001-08-28 | 2003-06-10 | The Brigham And Women's Hospital, Inc. | Treatment of patients at elevated cardiovascular risk with a combination of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin |
| US20040116510A1 (en) * | 2002-03-05 | 2004-06-17 | Nichtberger Steven A. | Antihypertensive agent and cholesterol absorption inhibitor combination therapy |
| WO2003090723A1 (en) * | 2002-04-23 | 2003-11-06 | Bristol-Myers Squibb Company | Modified-release vasopeptidase inhibitor formulation, combinations and method |
| BR0310100A (pt) * | 2002-05-17 | 2007-04-27 | Esperion Therapeutics Inc | métodos para tratar, prevenir ou reduzir a lesão de reperfusão isquêmica em um tecido ou órgão, e para prevenir ou tratar de uma condição associada com a privação de oxigênio, seguida por suprimento de oxigênio aumentado a um tecido ou órgão em necessidade disto |
| JP2006509774A (ja) * | 2002-10-03 | 2006-03-23 | ノバルティス アクチエンゲゼルシャフト | 2型糖尿病の処置において有用なグルコキナーゼアクチベーターとしての置換(チアゾール−2−イル)−アミドまたはスルホンアミド |
| BR0316386A (pt) * | 2002-12-06 | 2005-09-27 | Warner Lambert Co | Benzoxazin-3-onas e seus derivados como inibidores de p13k |
| JP2006512357A (ja) * | 2002-12-20 | 2006-04-13 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | Pi3kの阻害剤としてのベンゾキサジンおよびその誘導体 |
| TW200503994A (en) * | 2003-01-24 | 2005-02-01 | Novartis Ag | Organic compounds |
| KR100909918B1 (ko) * | 2003-05-20 | 2009-07-29 | 노파르티스 아게 | 과산화소체 증식체-활성화 수용체의 리간드로서의 n-아실질소 헤테로환 |
| CA2531418A1 (en) * | 2003-07-08 | 2005-01-20 | Novartis Ag | Benzenesulfonylamino compounds and pharmaceutical compositions containing these compounds |
| EP1648422A4 (en) * | 2003-07-28 | 2007-09-19 | Reddys Lab Inc Dr | TREATMENT AND PREVENTION OF CARDIOVASCULAR ACCIDENTS |
| US20050054731A1 (en) * | 2003-09-08 | 2005-03-10 | Franco Folli | Multi-system therapy for diabetes, the metabolic syndrome and obesity |
| US20050053648A1 (en) * | 2003-09-08 | 2005-03-10 | Chalmers Anne Marie | Medication delivery device |
| US20070116756A1 (en) * | 2005-11-23 | 2007-05-24 | Dr. Reddy's Laboratories Limited | Stable pharmaceutical compositions |
-
2004
- 2004-07-28 EP EP20040779390 patent/EP1648422A4/en not_active Withdrawn
- 2004-07-28 CA CA002531279A patent/CA2531279A1/en not_active Abandoned
- 2004-07-28 US US10/898,549 patent/US20050026992A1/en not_active Abandoned
- 2004-07-28 RU RU2006102356/15A patent/RU2380093C2/ru not_active IP Right Cessation
- 2004-07-28 CN CNA2004800204130A patent/CN1822820A/zh active Pending
- 2004-07-28 NZ NZ544784A patent/NZ544784A/en not_active IP Right Cessation
- 2004-07-28 AU AU2004261212A patent/AU2004261212B2/en not_active Ceased
- 2004-07-28 BR BRPI0412557-6A patent/BRPI0412557A/pt not_active Application Discontinuation
- 2004-07-28 WO PCT/US2004/024324 patent/WO2005011586A2/en not_active Ceased
-
2006
- 2006-01-25 ZA ZA200600733A patent/ZA200600733B/xx unknown
-
2009
- 2009-11-19 US US12/621,628 patent/US20100068269A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1648422A2 (en) | 2006-04-26 |
| EP1648422A4 (en) | 2007-09-19 |
| CA2531279A1 (en) | 2005-02-10 |
| RU2380093C2 (ru) | 2010-01-27 |
| AU2004261212A1 (en) | 2005-02-10 |
| WO2005011586A2 (en) | 2005-02-10 |
| AU2004261212B2 (en) | 2011-01-27 |
| US20100068269A1 (en) | 2010-03-18 |
| WO2005011586A3 (en) | 2005-07-07 |
| US20050026992A1 (en) | 2005-02-03 |
| CN1822820A (zh) | 2006-08-23 |
| RU2006102356A (ru) | 2007-09-10 |
| NZ544784A (en) | 2009-11-27 |
| ZA200600733B (en) | 2007-07-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
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