BRPI0412931A - tratamento da supressão de dependência - Google Patents
tratamento da supressão de dependênciaInfo
- Publication number
- BRPI0412931A BRPI0412931A BRPI0412931-8A BRPI0412931A BRPI0412931A BR PI0412931 A BRPI0412931 A BR PI0412931A BR PI0412931 A BRPI0412931 A BR PI0412931A BR PI0412931 A BRPI0412931 A BR PI0412931A
- Authority
- BR
- Brazil
- Prior art keywords
- buprenorphine
- dosage form
- dosage
- days
- dosing period
- Prior art date
Links
- 206010012335 Dependence Diseases 0.000 title 1
- 230000001629 suppression Effects 0.000 title 1
- RMRJXGBAOAMLHD-IHFGGWKQSA-N buprenorphine Chemical compound C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@]3([C@H](C1)[C@](C)(O)C(C)(C)C)OC)CN2CC1CC1 RMRJXGBAOAMLHD-IHFGGWKQSA-N 0.000 abstract 7
- 229960001736 buprenorphine Drugs 0.000 abstract 7
- 239000002552 dosage form Substances 0.000 abstract 4
- 239000006211 transdermal dosage form Substances 0.000 abstract 3
- 208000011580 syndromic disease Diseases 0.000 abstract 2
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B09—DISPOSAL OF SOLID WASTE; RECLAMATION OF CONTAMINATED SOIL
- B09B—DISPOSAL OF SOLID WASTE NOT OTHERWISE PROVIDED FOR
- B09B2101/00—Type of solid waste
- B09B2101/65—Medical waste
- B09B2101/68—Transdermal patches
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Addiction (AREA)
- Dermatology (AREA)
- Materials Engineering (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Reverberation, Karaoke And Other Acoustics (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
- Drying Of Semiconductors (AREA)
- Cephalosporin Compounds (AREA)
- Superconductors And Manufacturing Methods Therefor (AREA)
Abstract
"TRATAMENTO DA SUPRESSãO DE DEPENDêNCIA". A presente invenção refere-se a esquemas de buprenorfina para tratar supressão de droga ou síndrome de abstinência em uma paciente dependente de drogas ou tolerante a opiáceos, que está grávida. O método inclui tratar a supressão ou sindrome de abstinência da paciente pela administração transdérmica de uma quantidade de buprenorfina eficaz para reduzir os sintomas de supressão. Por exemplo, uma primeira forma de dosagem transdérmica que contém buprenorfina pode ser administrada por um primeiro período de dosagem que não é mais longo do que cerca de 5 dias; uma segunda forma de dosagem transdérmica que contém buprenorfina pode ser administrada por um segundo período de dosagem que não é mais longo do que cerca de 5 dias, onde a dita segunda forma de dosagem compreende a mesma dosagem de buprenorfina, ou uma dosagem de buprenorfina maior do que a dita primeira dosagem; e uma terceira forma de dosagem transdérmica que contém buprenorfina pode ser administrada por um terceiro período de dosagem de pelo menos 2 dias, onde a terceira forma de dosagem compreende a mesma dosagem ou uma dosagem maior de buprenorfina do que a segunda forma de dosagem.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49040703P | 2003-07-25 | 2003-07-25 | |
| PCT/US2004/024010 WO2005011579A2 (en) | 2003-07-25 | 2004-07-26 | Treatment of dependence withdrawal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0412931A true BRPI0412931A (pt) | 2006-09-26 |
Family
ID=34115390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0412931-8A BRPI0412931A (pt) | 2003-07-25 | 2004-07-26 | tratamento da supressão de dependência |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US8637073B2 (pt) |
| EP (1) | EP1646328B1 (pt) |
| JP (2) | JP2007500134A (pt) |
| KR (1) | KR100829492B1 (pt) |
| CN (1) | CN1829482B (pt) |
| AT (1) | ATE375149T1 (pt) |
| AU (1) | AU2004261182B2 (pt) |
| BR (1) | BRPI0412931A (pt) |
| CA (1) | CA2530005C (pt) |
| CY (1) | CY1107262T1 (pt) |
| DE (1) | DE602004009449T2 (pt) |
| DK (1) | DK1646328T3 (pt) |
| EA (1) | EA009921B1 (pt) |
| ES (1) | ES2295929T3 (pt) |
| GE (1) | GEP20125454B (pt) |
| HR (1) | HRP20070476T3 (pt) |
| IL (1) | IL173346A (pt) |
| IS (1) | IS2630B (pt) |
| MA (1) | MA28004A1 (pt) |
| MX (1) | MXPA06000991A (pt) |
| NO (1) | NO333189B1 (pt) |
| NZ (1) | NZ545505A (pt) |
| PL (1) | PL1646328T3 (pt) |
| PT (1) | PT1646328E (pt) |
| SI (1) | SI1646328T1 (pt) |
| UA (1) | UA81056C2 (pt) |
| WO (1) | WO2005011579A2 (pt) |
| ZA (1) | ZA200510069B (pt) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5968547A (en) | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| DE60322102D1 (de) | 2002-12-13 | 2008-08-21 | Euro Celtique Sa | Transdermales buprenorphin-dosierschema zwecks schmerzstillung |
| EP1913938A1 (en) * | 2002-12-13 | 2008-04-23 | Euro-Celtique S.A. | Transdermal buprenorphine dosage regimen for analgesia |
| EA009921B1 (ru) | 2003-07-25 | 2008-04-28 | Еуро-Селтик С.А. | Способ лечения синдрома отвыкания от зависимости у беременных женщин |
| KR20080058433A (ko) * | 2005-09-30 | 2008-06-25 | 티티아이 엘뷰 가부시키가이샤 | 오피오이드 작용제 및/또는 오피오이드 길항제를 이용한경피 약물 전달 시스템, 장치 및 방법 |
| WO2009106831A2 (en) * | 2008-02-28 | 2009-09-03 | Syntropharma Limited | Pharmaceutical composition |
| US8163731B2 (en) * | 2008-08-20 | 2012-04-24 | Rhodes Technologies | Method and dosage regimens for eliminating a chemical substance in blood |
| US9879204B2 (en) | 2010-03-17 | 2018-01-30 | Method Products, Pbc | Liquid cleaning compositions with lower freezing point |
| US11236351B2 (en) | 2010-05-17 | 2022-02-01 | Dow Agrosciences Llc | Production of DHA and other LC PUFAs in plants |
| TW201307553A (zh) | 2011-07-26 | 2013-02-16 | Dow Agrosciences Llc | 在植物中生產二十二碳六烯酸（ｄｈａ）及其他長鏈多元不飽和脂肪酸（ｌｃ－ｐｕｆａ）之技術 |
| MX2014011855A (es) * | 2012-04-17 | 2016-09-09 | Purdue Pharma Lp | Sistemas y metodos para tratar una respuesta farmacodinamica adversa inducida por opioides. |
| US9849124B2 (en) | 2014-10-17 | 2017-12-26 | Purdue Pharma L.P. | Systems and methods for treating an opioid-induced adverse pharmacodynamic response |
| US10925870B2 (en) | 2016-01-08 | 2021-02-23 | Ohio State Innovation Foundation | Treatments and prevention of opioid neonatal abstinence syndrome |
| JP2020526500A (ja) | 2017-06-30 | 2020-08-31 | パーデュー、ファーマ、リミテッド、パートナーシップ | 治療方法及びその剤形 |
| CN107648234A (zh) * | 2017-08-04 | 2018-02-02 | 中国人民解放军第二军医大学 | 一种治疗吗啡成瘾戒断症状的阿片类药物组合物 |
| EP3773497B1 (en) * | 2018-04-09 | 2023-10-18 | Elgan Pharma Ltd. | Oxytocin compositions and methods of use |
| WO2021043771A1 (en) * | 2019-09-02 | 2021-03-11 | Camurus Ab | Formulations and treatment methods |
| JP2024506861A (ja) | 2021-02-01 | 2024-02-15 | クリア サイエンティフィック，インク． | 物質使用障害の治療のための隔離化合物及びその使用 |
| EP4568672A2 (en) * | 2022-08-12 | 2025-06-18 | Bioventures, Llc | Deuterated buprenorphine as a protective agent for fetal subjects against full-agonist opioid exposure |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4058599A (en) | 1973-02-24 | 1977-11-15 | Bayer Aktiengesellschaft | Ethyleneimine inactivated organisms |
| DE3939376C1 (pt) | 1989-11-29 | 1991-05-08 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg, 5450 Neuwied, De | |
| US5075341A (en) | 1989-12-01 | 1991-12-24 | The Mclean Hospital Corporation | Treatment for cocaine abuse |
| EP0432945A1 (en) * | 1989-12-12 | 1991-06-19 | Warner-Lambert Company | A transdermal delivery system for treatment of cocaine and heroin addiction |
| US5272149A (en) | 1992-05-05 | 1993-12-21 | Stalling Reginald W | Symptom controlled receptor substitution for addiction withdrawl |
| JPH06183956A (ja) * | 1992-12-24 | 1994-07-05 | Teisan Seiyaku Kk | 安定な貼付用の製剤 |
| JP2819236B2 (ja) * | 1994-05-06 | 1998-10-30 | 日東電工株式会社 | 経皮吸収製剤 |
| EP0821957A3 (en) | 1996-08-01 | 1998-04-22 | Eli Lilly And Company | Use of 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine (xanomeline) for treating substance abuse |
| US5968547A (en) | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| KR100383252B1 (ko) * | 1998-12-17 | 2003-07-16 | 주식회사 삼양사 | 부프레놀핀을함유하는경피투여조성물및이를포함하는패취 |
| WO2003037313A2 (en) | 2001-10-31 | 2003-05-08 | Recovery Pharmaceuticals, Inc. | Methods for the treatment of addiction |
| DE60320770D1 (de) | 2002-03-20 | 2008-06-19 | Euro Celtique Sa | Verfahren zur verabreichung von buprenorphin zur behandlung von depression |
| DE60322102D1 (de) | 2002-12-13 | 2008-08-21 | Euro Celtique Sa | Transdermales buprenorphin-dosierschema zwecks schmerzstillung |
| WO2004103317A2 (en) | 2003-05-15 | 2004-12-02 | Euro-Celtique S.A. | Transdermal buprenorphine dosage regimen for treatment of diarrhea |
| EA009921B1 (ru) | 2003-07-25 | 2008-04-28 | Еуро-Селтик С.А. | Способ лечения синдрома отвыкания от зависимости у беременных женщин |
-
2004
- 2004-07-26 EA EA200600200A patent/EA009921B1/ru not_active IP Right Cessation
- 2004-07-26 WO PCT/US2004/024010 patent/WO2005011579A2/en not_active Ceased
- 2004-07-26 PL PL04779186T patent/PL1646328T3/pl unknown
- 2004-07-26 EP EP04779186A patent/EP1646328B1/en not_active Expired - Lifetime
- 2004-07-26 ES ES04779186T patent/ES2295929T3/es not_active Expired - Lifetime
- 2004-07-26 MX MXPA06000991A patent/MXPA06000991A/es active IP Right Grant
- 2004-07-26 JP JP2006521307A patent/JP2007500134A/ja active Pending
- 2004-07-26 HR HR20070476T patent/HRP20070476T3/xx unknown
- 2004-07-26 NZ NZ545505A patent/NZ545505A/en not_active IP Right Cessation
- 2004-07-26 DE DE602004009449T patent/DE602004009449T2/de not_active Expired - Lifetime
- 2004-07-26 BR BRPI0412931-8A patent/BRPI0412931A/pt not_active Application Discontinuation
- 2004-07-26 AU AU2004261182A patent/AU2004261182B2/en not_active Ceased
- 2004-07-26 CN CN2004800215633A patent/CN1829482B/zh not_active Expired - Fee Related
- 2004-07-26 DK DK04779186T patent/DK1646328T3/da active
- 2004-07-26 SI SI200430545T patent/SI1646328T1/sl unknown
- 2004-07-26 AT AT04779186T patent/ATE375149T1/de active
- 2004-07-26 US US10/566,121 patent/US8637073B2/en active Active
- 2004-07-26 UA UAA200602136A patent/UA81056C2/uk unknown
- 2004-07-26 GE GEAP20049184A patent/GEP20125454B/en unknown
- 2004-07-26 CA CA2530005A patent/CA2530005C/en not_active Expired - Fee Related
- 2004-07-26 KR KR1020067001688A patent/KR100829492B1/ko not_active Expired - Fee Related
- 2004-07-26 PT PT04779186T patent/PT1646328E/pt unknown
-
2005
- 2005-12-12 ZA ZA200510069A patent/ZA200510069B/en unknown
- 2005-12-19 IS IS8187A patent/IS2630B/is unknown
-
2006
- 2006-01-24 IL IL173346A patent/IL173346A/en not_active IP Right Cessation
- 2006-02-23 MA MA28830A patent/MA28004A1/fr unknown
- 2006-02-24 NO NO20060913A patent/NO333189B1/no not_active IP Right Cessation
-
2008
- 2008-01-08 CY CY20081100020T patent/CY1107262T1/el unknown
-
2011
- 2011-08-18 JP JP2011179129A patent/JP2011252020A/ja active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25G | Requested change of headquarter approved |
Owner name: EURO-CELTIQUE S.A. (LU) |
|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Ipc: A61K 9/70 (2006.01), A61K 31/485 (2006.01), A61L 1 |
|
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |