BRPI0413201A - cápsulas contendo péletes de substáncias ativas com diversos perfis de desprendimento - Google Patents

cápsulas contendo péletes de substáncias ativas com diversos perfis de desprendimento

Info

Publication number
BRPI0413201A
BRPI0413201A BRPI0413201-7A BRPI0413201A BRPI0413201A BR PI0413201 A BRPI0413201 A BR PI0413201A BR PI0413201 A BRPI0413201 A BR PI0413201A BR PI0413201 A BRPI0413201 A BR PI0413201A
Authority
BR
Brazil
Prior art keywords
active substance
active substances
different
substance pellets
release profiles
Prior art date
Application number
BRPI0413201-7A
Other languages
English (en)
Inventor
Sergej Anschuetz
Roland Schneider
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of BRPI0413201A publication Critical patent/BRPI0413201A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A23L33/155—Vitamins A or D
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

"CáPSULAS CONTENDO PéLETES DE SUBSTáNCIAS ATIVAS COM DIVERSOS PERFIS DE DESPRENDIMENTO". A invenção refere-se a uma cápsula contendo diferentes péletes de substâncias ativas com pelo menos duas substâncias ativas diferentes, que diferenciam-se tendo em vista seu perfil de liberação no trato gastrointestinal, sendo que as substâncias ativas são escolhidas do grupo das vitaminas, sais minerais, elementos traço, ácidos graxos insaturados, aminoácidos e/ou extratos e substâncias vegetais. Os perfis de liberação os mais diferentes apresentam uma rápida, média e/ou lenta dissolução dos péletes de substância ativa. Essa liberação controlada leva a uma reabsorção alvo-orientada das substâncias ativas nos diferentes âmbitos de reabsorção do trato gastrointestinal. Através das formas de aplicação preparadas de acordo com a invenção pode-se aperfeiçoar a biodisponibilidade, mesmo no caso de um número maior de substâncias ativas presentes.
BRPI0413201-7A 2003-09-03 2004-08-28 cápsulas contendo péletes de substáncias ativas com diversos perfis de desprendimento BRPI0413201A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03019577 2003-09-03
PCT/EP2004/009617 WO2005023229A1 (de) 2003-09-03 2004-08-28 Kapsel enthaltend wirkstoffpellets mit unterschiedlichen freisetzungsprofilen

Publications (1)

Publication Number Publication Date
BRPI0413201A true BRPI0413201A (pt) 2006-10-03

Family

ID=34259144

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0413201-7A BRPI0413201A (pt) 2003-09-03 2004-08-28 cápsulas contendo péletes de substáncias ativas com diversos perfis de desprendimento

Country Status (17)

Country Link
US (1) US20050058704A1 (pt)
EP (1) EP1667665B1 (pt)
JP (1) JP4897483B2 (pt)
AT (1) ATE419841T1 (pt)
BR (1) BRPI0413201A (pt)
CA (1) CA2537477C (pt)
CY (1) CY1108950T1 (pt)
DE (1) DE502004008834D1 (pt)
DK (1) DK1667665T3 (pt)
ES (1) ES2317024T3 (pt)
MX (1) MXPA06002316A (pt)
PL (1) PL1667665T3 (pt)
PT (1) PT1667665E (pt)
RU (1) RU2356540C2 (pt)
SI (1) SI1667665T1 (pt)
UA (1) UA87471C2 (pt)
WO (1) WO2005023229A1 (pt)

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* Cited by examiner, † Cited by third party
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US20050053648A1 (en) * 2003-09-08 2005-03-10 Chalmers Anne Marie Medication delivery device
JP5171038B2 (ja) * 2003-10-10 2013-03-27 エティファルム イチョウ・エキスを含む放出持続性の微小顆粒およびそのような顆粒の製造方法
US20060252830A1 (en) * 2005-05-06 2006-11-09 Brandon Stephen F Method for the treatment of magnesium and potassium deficiencies
US20060252831A1 (en) * 2005-05-06 2006-11-09 Christopher Offen Method for the treatment of magnesium and potassium deficiencies
DE102006006532B4 (de) 2006-02-10 2007-11-08 Biogenerics Pharma Gmbh Pharmazeutische Zubereitung
EP2010162A4 (en) * 2006-04-03 2013-01-09 Isa Odidi COMPOSITION FOR DISPOSING A MEDICINAL PRODUCT
JP5467870B2 (ja) * 2007-02-09 2014-04-09 アルファファーム ピーティーワイ リミテッド 異なる物理的形態の２種以上の有効医薬成分を含有する投薬形態
CA2718571A1 (en) * 2007-03-12 2008-09-18 Pipex Pharmaceuticals, Inc. Oral zinc medicants useful for safely lowering free copper absorption and free copper levels
WO2008112706A1 (en) 2007-03-13 2008-09-18 Nutrition 21, Inc. Methods and compositions for the sustained release of chromium
WO2009002867A2 (en) 2007-06-26 2008-12-31 Nutrition 21, Inc. Multiple unit dosage form having a therapeutic agents in combination with a nutritional supplement
EP2229155A4 (en) * 2007-12-12 2010-12-29 Northern Innovations And Formulations Corp Particles in a capsule
US8445020B2 (en) * 2008-05-19 2013-05-21 Pharmalyte Solutions, Llc High-loading, controlled-release magnesium oral dosage forms and methods of making and using same
US20110123609A1 (en) * 2008-07-19 2011-05-26 Sunil Shantwan Borude Multiple unit dosage form of niacin
US20130011469A1 (en) * 2009-07-23 2013-01-10 U.S. Nutraceuticals, Llc D/B/A Valensa International Krill oil and carotenoid composition, associated method and delivery system
CN102038691B (zh) * 2009-10-12 2014-06-11 杭州赛利药物研究所有限公司 一种维生素氨基酸的复合制剂及其制备方法
DE102010022174A1 (de) * 2010-05-12 2011-11-17 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Neue Darreichungsformen für Cineol
WO2014071176A1 (en) * 2012-11-02 2014-05-08 Disilvestro Robert Nutritional supplements including meal replacements and related methods
US20150104539A1 (en) * 2013-10-15 2015-04-16 Via Naturally, LLC Citrated folic acid compositions and methods for delivering folic acid to usp dissolution specifications
GB2564295A (en) 2016-02-11 2019-01-09 Nutrition 21 Llc Chromium containing compositions for improving health and fitness
CA3033973A1 (en) * 2016-08-15 2018-02-22 Corr-Jensen Inc. Time release of fat-soluble actives
ES2695503B2 (es) * 2017-06-30 2020-05-08 Pharmalink S L Formulaciones encapsuladas
KR102368654B1 (ko) * 2020-04-17 2022-02-28 주식회사 청안오가닉스 녹차 카테킨을 포함하는 경구용 캡슐
US20230255930A1 (en) * 2020-07-09 2023-08-17 Dsm Ip Assets B.V. Method of increasing the population of coprococcus spp. in the gut microbiome
CN111821266B (zh) * 2020-07-17 2021-09-14 迪沙药业集团有限公司 一种牛磺酸缓释组合物及其制备方法

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JPS50151874U (pt) * 1974-06-01 1975-12-17
JPS5347513A (en) * 1976-10-14 1978-04-28 Meiji Seika Kaisha Ltd Preparation of enzymatic agent
US4507276A (en) * 1982-08-20 1985-03-26 Bristol-Myers Company Analgesic capsule
JPS5982311A (ja) * 1982-11-04 1984-05-12 Shionogi & Co Ltd セフアレキシン持効性製剤
US5260068A (en) * 1992-05-04 1993-11-09 Anda Sr Pharmaceuticals Inc. Multiparticulate pulsatile drug delivery system
ATE183641T1 (de) * 1992-12-23 1999-09-15 Saitec Srl Verfahren zur herstellung von arzneiformen und kontrollierte freigabe und die soerhaltenen arzneiformen
FR2705233B1 (fr) * 1993-05-14 1996-07-12 Atheliapharm Sa Nouvelles formes galéniques permettant la chronolibération différentielle d'associations de micronutriments utilisés en diététique et/ou thérapeutique.
US5837284A (en) * 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
IT1283478B1 (it) * 1996-07-22 1998-04-21 Roberto Valducci Composizioni per integrazione nutrizionale comprendenti vitamine idrosolubili a rilascio prolungato
JP2000507613A (ja) * 1996-11-01 2000-06-20 アイレックス・オンコロジー・インコーポレイテッド Ｄｆｍｏ含有持続放出配合物
SE9704870D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulation I
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Also Published As

Publication number Publication date
DK1667665T3 (da) 2009-05-04
CA2537477C (en) 2013-05-14
EP1667665B1 (de) 2009-01-07
PL1667665T3 (pl) 2009-06-30
CY1108950T1 (el) 2014-07-02
ATE419841T1 (de) 2009-01-15
PT1667665E (pt) 2009-02-13
SI1667665T1 (sl) 2009-06-30
ES2317024T3 (es) 2009-04-16
MXPA06002316A (es) 2006-05-19
RU2006110549A (ru) 2007-10-10
US20050058704A1 (en) 2005-03-17
EP1667665A1 (de) 2006-06-14
WO2005023229A1 (de) 2005-03-17
DE502004008834D1 (de) 2009-02-26
CA2537477A1 (en) 2005-03-17
UA87471C2 (uk) 2009-07-27
RU2356540C2 (ru) 2009-05-27
JP4897483B2 (ja) 2012-03-14
JP2007504189A (ja) 2007-03-01

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: AS CLASSIFICACOES ANTERIORES ERAM: A61K 9/50 , A23L 1/302 , A23L 1/303 , A23L 1/304 , A23L 1/305

Ipc: A61K 9/50 (2006.01), A61K 9/54 (2006.01), A23L 33/

B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]