BRPI0413364A - proteases especìficas de ubiquitina - Google Patents
proteases especìficas de ubiquitinaInfo
- Publication number
- BRPI0413364A BRPI0413364A BRPI0413364-1A BRPI0413364A BRPI0413364A BR PI0413364 A BRPI0413364 A BR PI0413364A BR PI0413364 A BRPI0413364 A BR PI0413364A BR PI0413364 A BRPI0413364 A BR PI0413364A
- Authority
- BR
- Brazil
- Prior art keywords
- useful
- specific proteases
- ubiquitin
- well
- present
- Prior art date
Links
- 102000018390 Ubiquitin-Specific Proteases Human genes 0.000 title 1
- 108010066496 Ubiquitin-Specific Proteases Proteins 0.000 title 1
- 208000014644 Brain disease Diseases 0.000 abstract 1
- 206010006187 Breast cancer Diseases 0.000 abstract 1
- 208000026310 Breast neoplasm Diseases 0.000 abstract 1
- 102000001477 Deubiquitinating Enzymes Human genes 0.000 abstract 1
- 108010093668 Deubiquitinating Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000035195 Peptidases Human genes 0.000 abstract 1
- 108091005804 Peptidases Proteins 0.000 abstract 1
- 239000004365 Protease Substances 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 208000032839 leukemia Diseases 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"PROTEASES ESPECìFICAS DE UBIQUITINA". A presente invenção refere-se a novos membros da família de enzimas desubiquitinação (DUBs), bem como fragmentos, derivados, e homólogos destes, biologicamente, diagnosticamente ou terapeuticamente úteis, que são úteis em propósitos de pesquisas, biológicos, clínicos, terapêuticos, bem como prognósticos e diagnósticos. Além disso, os polinucleotídeos e polipeptídeos fornecidos pela presente invenção são úteis para o tratamento e diagnose de câncer de mama, leucemia ou distúrbios cerebrais.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49308003P | 2003-08-06 | 2003-08-06 | |
| PCT/EP2004/008798 WO2005014804A2 (en) | 2003-08-06 | 2004-08-05 | Ubiquitin-specific protease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0413364A true BRPI0413364A (pt) | 2006-10-17 |
Family
ID=34135200
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0413364-1A BRPI0413364A (pt) | 2003-08-06 | 2004-08-05 | proteases especìficas de ubiquitina |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1651764A2 (pt) |
| JP (1) | JP2007501008A (pt) |
| CN (1) | CN1845994A (pt) |
| AU (1) | AU2004262684A1 (pt) |
| BR (1) | BRPI0413364A (pt) |
| CA (1) | CA2534481A1 (pt) |
| MX (1) | MXPA06001393A (pt) |
| WO (1) | WO2005014804A2 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2182073B1 (en) * | 2008-10-30 | 2014-04-16 | Les Laboratoires Servier | Ubiquitin specific proteases responsible for MCL-1 stability and uses thereof |
| RU2603093C2 (ru) | 2010-04-15 | 2016-11-20 | Дженентек, Инк. | Антитела против полиубиквитина и способы их применения |
| CN103205400B (zh) * | 2013-04-19 | 2014-09-17 | 青岛大学医学院附属医院 | 含有人泛素特异性蛋白酶基因USP39-shRNA的重组慢病毒及其应用 |
| KR20210125476A (ko) * | 2018-12-07 | 2021-10-18 | 옥탄트, 인크. | 단백질-단백질 상호작용 스크리닝을 위한 시스템 |
| CN116855497B (zh) * | 2023-07-10 | 2025-09-12 | 暨南大学 | 一种抑制人USP46基因表达的siRNA和脂质体及其应用 |
| CN117106911A (zh) * | 2023-08-14 | 2023-11-24 | 首都医科大学附属北京天坛医院 | 检测神经鞘瘤的基因集及其多重pcr-高通量测序检测试剂盒 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001271427A1 (en) * | 2000-06-26 | 2002-01-08 | Sugen, Inc. | Novel proteases |
| JP2002300880A (ja) * | 2001-04-04 | 2002-10-15 | Dai Ichi Seiyaku Co Ltd | 新規ユビキチン特異プロテアーゼ |
-
2004
- 2004-08-05 CN CNA2004800256544A patent/CN1845994A/zh active Pending
- 2004-08-05 WO PCT/EP2004/008798 patent/WO2005014804A2/en not_active Ceased
- 2004-08-05 EP EP04741374A patent/EP1651764A2/en not_active Withdrawn
- 2004-08-05 AU AU2004262684A patent/AU2004262684A1/en not_active Abandoned
- 2004-08-05 JP JP2006522322A patent/JP2007501008A/ja not_active Withdrawn
- 2004-08-05 MX MXPA06001393A patent/MXPA06001393A/es not_active Application Discontinuation
- 2004-08-05 BR BRPI0413364-1A patent/BRPI0413364A/pt not_active Application Discontinuation
- 2004-08-05 CA CA002534481A patent/CA2534481A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA06001393A (es) | 2006-08-25 |
| EP1651764A2 (en) | 2006-05-03 |
| CN1845994A (zh) | 2006-10-11 |
| JP2007501008A (ja) | 2007-01-25 |
| CA2534481A1 (en) | 2005-02-17 |
| WO2005014804A2 (en) | 2005-02-17 |
| WO2005014804A3 (en) | 2005-06-30 |
| AU2004262684A1 (en) | 2005-02-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired |