BRPI0414192A - oral itraconazole composition that is unaffected by food intake and process for preparing itraconazole - Google Patents

oral itraconazole composition that is unaffected by food intake and process for preparing itraconazole

Info

Publication number
BRPI0414192A
BRPI0414192A BRPI0414192-0A BRPI0414192A BRPI0414192A BR PI0414192 A BRPI0414192 A BR PI0414192A BR PI0414192 A BRPI0414192 A BR PI0414192A BR PI0414192 A BRPI0414192 A BR PI0414192A
Authority
BR
Brazil
Prior art keywords
itraconazole
composition
oral
food intake
unaffected
Prior art date
Application number
BRPI0414192-0A
Other languages
Portuguese (pt)
Inventor
Jong Soo Woo
Hong Gi Yi
Original Assignee
Hanmi Pharm Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanmi Pharm Ind Co Ltd filed Critical Hanmi Pharm Ind Co Ltd
Priority claimed from PCT/KR2004/002264 external-priority patent/WO2005023262A1/en
Publication of BRPI0414192A publication Critical patent/BRPI0414192A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"COMPOSIçãO DE ITRACONAZOL ORAL QUE NãO é AFETADA POR ALIMENTO INGERIDO E PROCESSO PARA PREPARAR A MESMA". Uma composição viscosa e vítrea para administração oral compreendendo itraconazol, agente acidulante, um aditivo anfifílico, um tensoativo e um óleo fornece uma alta bio-disponibilidade in vivo de itraconazol que é pouco influenciada por alimento ingerido."COMPOSITION OF ORAL ITRACONAZOL THAT IS NOT AFFECTED BY FOOD EATING AND PROCESS TO PREPARE IT". A viscous and vitreous composition for oral administration comprising itraconazole, acidifying agent, an amphiphilic additive, a surfactant and an oil provides a high in vivo bioavailability of itraconazole which is little influenced by food intake.

BRPI0414192-0A 2003-09-09 2004-09-07 oral itraconazole composition that is unaffected by food intake and process for preparing itraconazole BRPI0414192A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2003-0063147A KR100529766B1 (en) 2003-09-09 2003-09-09 Oral itraconazole composition which is not affected by ingested food and preparation thereof
PCT/KR2004/002264 WO2005023262A1 (en) 2003-09-09 2004-09-07 Oral itraconazole composition which is not affected by ingested food and process for preparing same

Publications (1)

Publication Number Publication Date
BRPI0414192A true BRPI0414192A (en) 2006-10-31

Family

ID=36096818

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0414192-0A BRPI0414192A (en) 2003-09-09 2004-09-07 oral itraconazole composition that is unaffected by food intake and process for preparing itraconazole

Country Status (10)

Country Link
EP (1) EP1663231A4 (en)
JP (1) JP2007505103A (en)
KR (1) KR100529766B1 (en)
CN (1) CN100475211C (en)
AU (1) AU2004270069B2 (en)
BR (1) BRPI0414192A (en)
CA (1) CA2538019C (en)
IL (1) IL173743A (en)
MX (1) MXPA06002239A (en)
RU (1) RU2006111477A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013192566A1 (en) 2012-06-21 2013-12-27 Mayne Pharma International Pty. Ltd. Itraconazole compositions and dosage forms, and methods of using the same
CN104688536B (en) * 2015-02-03 2016-06-08 常州制药厂有限公司 A kind of preparation method of itraconazole preparation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100336090B1 (en) * 1998-06-27 2002-05-27 윤승원 Solid dispersed preparation of poorly water-soluble drug containing oil, fatty acid or mixture thereof
US6383471B1 (en) * 1999-04-06 2002-05-07 Lipocine, Inc. Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
KR100435141B1 (en) * 2000-12-28 2004-06-09 한미약품 주식회사 Composition for oral administration of poorly soluble antifungal agent and process for the preparation thereof
KR100455216B1 (en) * 2001-06-27 2004-11-09 한미약품 주식회사 Composition for oral administration of poorly soluble antifungal agent and process for the preparation thereof

Also Published As

Publication number Publication date
KR20050026169A (en) 2005-03-15
IL173743A0 (en) 2006-07-05
CN100475211C (en) 2009-04-08
CA2538019C (en) 2009-09-01
IL173743A (en) 2012-08-30
CA2538019A1 (en) 2005-03-17
AU2004270069B2 (en) 2008-03-13
MXPA06002239A (en) 2006-06-20
CN1849123A (en) 2006-10-18
RU2006111477A (en) 2006-08-27
JP2007505103A (en) 2007-03-08
KR100529766B1 (en) 2005-11-17
AU2004270069A1 (en) 2005-03-17
EP1663231A4 (en) 2009-04-29
EP1663231A1 (en) 2006-06-07

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2166 DE 10/07/2012.