BRPI0414442A - composições de vacina de dna e métodos de utilização - Google Patents

composições de vacina de dna e métodos de utilização

Info

Publication number
BRPI0414442A
BRPI0414442A BRPI0414442-2A BRPI0414442A BRPI0414442A BR PI0414442 A BRPI0414442 A BR PI0414442A BR PI0414442 A BRPI0414442 A BR PI0414442A BR PI0414442 A BRPI0414442 A BR PI0414442A
Authority
BR
Brazil
Prior art keywords
methods
dna vaccine
dna molecule
vaccine compositions
dna
Prior art date
Application number
BRPI0414442-2A
Other languages
English (en)
Inventor
Opendra Narayan
Zhenqian Liu
Original Assignee
Univ Kansas Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kansas Medical Center filed Critical Univ Kansas Medical Center
Publication of BRPI0414442A publication Critical patent/BRPI0414442A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"COMPOSIçõES DE VACINA DE DNA E MéTODOS DE UTILIZAçãO". A presente invenção refere-se a uma vacina de DNA para imunização contra o HIV. A presente invenção compreende uma molécula de DNA que possui uma seqüência codificando diversas proteínas virais capazes de estimular uma resposta imunológica contra o HIV. A molécula de DNA é apresentada como sendo segura para utilização na forma de uma vacina devido à ruptura dos genes que codificam a transcritase reversa, a integrase e a Vif. A molécula de DNA é adicionalmente apresentada como segura devido, pelo menos, a uma eliminação parcial da LTR 3<39>.
BRPI0414442-2A 2003-09-16 2004-09-16 composições de vacina de dna e métodos de utilização BRPI0414442A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50319703P 2003-09-16 2003-09-16
US10/941,164 US7488485B2 (en) 2003-09-16 2004-09-15 DNA vaccine compositions and methods of use
PCT/US2004/030512 WO2005027844A2 (en) 2003-09-16 2004-09-16 Dna vaccine compositions and methods of use

Publications (1)

Publication Number Publication Date
BRPI0414442A true BRPI0414442A (pt) 2006-11-14

Family

ID=34381064

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0414442-2A BRPI0414442A (pt) 2003-09-16 2004-09-16 composições de vacina de dna e métodos de utilização

Country Status (13)

Country Link
US (3) US7488485B2 (pt)
EP (1) EP1667523B1 (pt)
JP (1) JP4989224B2 (pt)
AU (1) AU2004273965B2 (pt)
BR (1) BRPI0414442A (pt)
CA (1) CA2538840C (pt)
DK (1) DK1667523T3 (pt)
ES (1) ES2399875T3 (pt)
IL (1) IL174325A (pt)
NZ (1) NZ545954A (pt)
PL (1) PL1667523T3 (pt)
PT (1) PT1667523E (pt)
WO (1) WO2005027844A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7488485B2 (en) * 2003-09-16 2009-02-10 University Of Kansas Medical Center DNA vaccine compositions and methods of use
US8765140B2 (en) * 2003-09-16 2014-07-01 University Of Kansas Medical Center DNA vaccine compositions with HIV/SIV gene modifications
ES2541771T3 (es) * 2005-05-03 2015-07-24 INSERM (Institut National de la Santé et de la Recherche Médicale) Expresión de una proteína mitocondrial mediante un enfoque alotópico mejorado
US7585675B2 (en) * 2005-11-15 2009-09-08 University Of Kansas Medical Center Inhibition of HIV and SHIV replication with antisense interleukin-4
FR2979919B1 (fr) * 2011-09-12 2015-12-11 Centre Nat Rech Scient Genomes lentiviraux chimeriques non-integratifs comme vaccins innovants contre vih-1
US20130337009A1 (en) * 2012-02-21 2013-12-19 Immunogenetix Therapeutics, Inc. Chimeric dna vaccine compositions and methods of use
AU2020315598B2 (en) 2019-07-16 2024-12-12 Gilead Sciences, Inc. HIV vaccines and methods of making and using
CA3202466A1 (en) 2021-01-14 2022-07-21 Jiani LI Hiv vaccines and methods of using
AU2022208435A1 (en) 2021-01-18 2023-08-10 Conserv Bioscience Limited Coronavirus immunogenic compositions, methods and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5741492A (en) * 1996-01-23 1998-04-21 St. Jude Children's Research Hospital Preparation and use of viral vectors for mixed envelope protein vaccines against human immunodeficiency viruses
US6531123B1 (en) * 1997-05-01 2003-03-11 Lung-Ji Chang Lentiviral vectors
US7488485B2 (en) * 2003-09-16 2009-02-10 University Of Kansas Medical Center DNA vaccine compositions and methods of use
US7122180B2 (en) * 2000-10-23 2006-10-17 Children's Medical Center Corporation DNA vectors containing mutated HIV proviruses

Also Published As

Publication number Publication date
WO2005027844A3 (en) 2005-10-06
JP4989224B2 (ja) 2012-08-01
DK1667523T3 (da) 2013-01-21
US7488485B2 (en) 2009-02-10
PT1667523E (pt) 2013-02-04
US20120207782A1 (en) 2012-08-16
IL174325A (en) 2015-07-30
US8003113B2 (en) 2011-08-23
US20050112102A1 (en) 2005-05-26
US20090233857A1 (en) 2009-09-17
AU2004273965A1 (en) 2005-03-31
CA2538840C (en) 2014-02-18
CA2538840A1 (en) 2005-03-31
US8916174B2 (en) 2014-12-23
PL1667523T3 (pl) 2013-05-31
NZ545954A (en) 2009-04-30
ES2399875T3 (es) 2013-04-04
EP1667523B1 (en) 2012-11-21
WO2005027844A2 (en) 2005-03-31
EP1667523A2 (en) 2006-06-14
IL174325A0 (en) 2008-04-13
AU2004273965B2 (en) 2010-12-09
EP1667523A4 (en) 2007-12-19
JP2007505923A (ja) 2007-03-15

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Legal Events

Date Code Title Description
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DA INT. CL. A01N 43/04, A01N 63/00, A61K 39/21, C07H 21/04, C12N 15/00, C12N 15/63, C12N 15/86.

Ipc: A61K 39/21 (2006.01), A61K 48/00 (2006.01), C07H 2

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2479 DE 10-07-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI