BRPI0415634A - formulação para cápsulas de gelatina macia contendo retinóides - Google Patents

formulação para cápsulas de gelatina macia contendo retinóides

Info

Publication number
BRPI0415634A
BRPI0415634A BRPI0415634-0A BRPI0415634A BRPI0415634A BR PI0415634 A BRPI0415634 A BR PI0415634A BR PI0415634 A BRPI0415634 A BR PI0415634A BR PI0415634 A BRPI0415634 A BR PI0415634A
Authority
BR
Brazil
Prior art keywords
soft gelatin
formulation
retinoid
gelatin capsules
vegetable oil
Prior art date
Application number
BRPI0415634-0A
Other languages
English (en)
Inventor
Guenter Ditzinger
Bernhard Gabriel
Anne-Hortense Schmitt-Hoffmann
Lutz Wevelsiep
Original Assignee
Basilea Pharmaceutica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34178692&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0415634(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Basilea Pharmaceutica Ag filed Critical Basilea Pharmaceutica Ag
Publication of BRPI0415634A publication Critical patent/BRPI0415634A/pt
Publication of BRPI0415634B1 publication Critical patent/BRPI0415634B1/pt
Publication of BRPI0415634B8 publication Critical patent/BRPI0415634B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

"FORMULAçãO PARA CáPSULAS DE GELATINA MACIA CONTENDO RETINóIDES". A presente invenção refere-se a uma nova formulação farmacêutica para cápsulas de gelatina macia contendo retinóide. A nova formulação contém uma cápsula de gelatina macia recheada com uma massa de recheio contendo um retinóide como um ingrediente ativo, um óleo vegetal natural, um óleo vegetal natural parcialmente hidrogenado e triglicerídeos de cadeia média. Opcionalmente, a nova formulação contém também uma cera natural. Em uma modalidade particularmente preferida, a cápsula de gelatina macia inclui gelatina suína na casca da cápsula em combinação com a massa de recheio acima.
BRPI0415634A 2003-11-03 2004-10-28 formulação para cápsulas de gelatina macia contendo retinóides BRPI0415634B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03405788A EP1527774A1 (en) 2003-11-03 2003-11-03 New formulation for retinoid-containing soft gelatin capsules
EP03405788.5 2003-11-03
PCT/EP2004/012208 WO2005048994A1 (en) 2003-11-03 2004-10-28 New formulation for retinoid-containing soft gelatin capsules

Publications (3)

Publication Number Publication Date
BRPI0415634A true BRPI0415634A (pt) 2006-12-12
BRPI0415634B1 BRPI0415634B1 (pt) 2018-12-26
BRPI0415634B8 BRPI0415634B8 (pt) 2021-05-25

Family

ID=34178692

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0415634A BRPI0415634B8 (pt) 2003-11-03 2004-10-28 formulação para cápsulas de gelatina macia contendo retinóides

Country Status (21)

Country Link
US (6) US20050042278A1 (pt)
EP (2) EP1527774A1 (pt)
JP (1) JP4555827B2 (pt)
KR (1) KR100856362B1 (pt)
CN (1) CN100594894C (pt)
AT (1) ATE392204T1 (pt)
AU (1) AU2004290494B2 (pt)
BR (1) BRPI0415634B8 (pt)
CA (1) CA2541292C (pt)
CY (1) CY1108184T1 (pt)
DE (1) DE602004013178T2 (pt)
DK (1) DK1680096T3 (pt)
ES (1) ES2303956T3 (pt)
MX (1) MXPA06003821A (pt)
NO (1) NO339743B1 (pt)
NZ (1) NZ546258A (pt)
PL (1) PL1680096T3 (pt)
PT (1) PT1680096E (pt)
RU (1) RU2344810C2 (pt)
SI (1) SI1680096T1 (pt)
WO (1) WO2005048994A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8541469B2 (en) * 1997-08-23 2013-09-24 Glaxo Group Limited Treatment of cell-mediated immune diseases
CA2471831C (en) 2001-12-26 2011-07-19 Research In Motion Limited User interface and method of viewing unified communications events on a mobile device
US20080112987A1 (en) * 2006-11-10 2008-05-15 National Starch And Chemical Investment Holding Corporation Coating for oxygen sensitive materials
LV13888B (lv) * 2008-12-04 2009-06-20 Rigas Stradina Uni Skuju biezo ekstraktu saturošs sastāvs iekapsulēšanai
CN102612375B (zh) * 2009-09-15 2016-01-27 Qlt股份有限公司 含有在脂质媒介物中的9-顺式-视黄酯的药物制剂
CN107308143A (zh) 2010-04-19 2017-11-03 诺维利昂治疗股份有限公司 用于治疗或改善与内源性类视黄醇缺乏有关的视觉障碍的治疗方案和方法
JP6576636B2 (ja) 2012-03-01 2019-09-18 ノベリオン セラピューティクス インコーポレイテッド 内因性レチノイド欠乏に関連する視覚障害における視覚機能を改善するための治療的計画および方法
CN102716103B (zh) * 2012-07-02 2013-12-18 西安力邦制药有限公司 2,2′,6,6′-四异丙基-4,4′-二联苯酚软胶囊制剂及其制备方法
WO2018060866A1 (en) * 2016-09-28 2018-04-05 Dr. Reddy’S Laboratories Limited Oral retinoid compositions
CN107157966B (zh) * 2017-06-14 2021-04-13 程刚 一种纳米包裹视黄醛祛痘凝胶及其制备方法
KR102108153B1 (ko) * 2017-07-05 2020-05-07 (주)동구바이오제약 생체 이용률 및 안정성이 개선된 레티노이드를 함유하는 약제학적 조성물
CN109512795A (zh) * 2018-12-24 2019-03-26 浙江安宝药业有限公司 维生素a软胶囊
CN112618509A (zh) * 2019-09-24 2021-04-09 重庆华邦制药有限公司 一种维a酸软胶囊及其制备方法
RU2744142C1 (ru) * 2019-12-06 2021-03-03 Общество с ограниченной ответственностью "Артлайф" Композиция для профилактики грибковых заболеваний
CN113332258A (zh) * 2021-06-30 2021-09-03 山东良福制药有限公司 维a酸硬胶囊及其制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1282326C (en) * 1984-12-14 1991-04-02 Paul J. Jarosz Pharmaceutical composition containing 13-cis vitamin a acid as the active ingredient
US5082661A (en) * 1990-09-26 1992-01-21 Elizabeth Arden Co., Division Of Conopco, Inc. Odorless cosmetic compositions in gelatin capsules
JP2712056B2 (ja) * 1992-01-14 1998-02-10 久光製薬株式会社 コレステロール低下剤
CZ282548B6 (cs) * 1992-01-22 1997-08-13 F. Hoffmann-La Roche Ag Farmaceutický přípravek
KR100274101B1 (ko) * 1992-01-22 2000-12-15 프리돌린 클라우스너, 롤란드 비. 보레르 9-시스 레틴산을 함유하는 약제학적 조성물
CA2093577C (en) 1992-05-07 2006-01-03 Michael Klaus Alkyl or alkoxy substituted s-heterocyclic retinoids
DE19603402A1 (de) * 1995-02-24 1996-08-29 Basf Ag Weichgelatinekapseln
KR0173445B1 (ko) * 1996-09-17 1999-02-01 이능희 화장료용 이중캡슐 및 이를 함유하는 화장료 조성물
EP0908179A1 (en) 1997-08-23 1999-04-14 Werner Bollag Treatment of cell-mediated immune diseases
EP1030662B1 (en) * 1997-11-12 2006-08-02 F. Hoffmann-La Roche Ag Treatment of t-helper cell type 2 mediated immune diseases with retinoid antagonists
PE20001227A1 (es) * 1998-10-30 2000-11-06 Hoffmann La Roche Procesos para producir una composicion de isotretinoina
US6248354B1 (en) * 1999-03-04 2001-06-19 Allergan Sales, Inc. Capsule system
US6468559B1 (en) * 2000-04-28 2002-10-22 Lipocine, Inc. Enteric coated formulation of bishosphonic acid compounds and associated therapeutic methods
WO2001095856A2 (en) 2000-06-15 2001-12-20 Chaconne Nsi Co., Ltd. Urea derivative useful as an anti-cancer agent and process for preparing same
IN192188B (pt) 2000-06-16 2004-03-13 Ranbaxy Lab Ltd
EP1201686B1 (en) * 2000-10-23 2006-07-19 Mitsubishi Gas Chemical Company, Inc. Methyl methacrylate syrup and production thereof

Also Published As

Publication number Publication date
NO339743B1 (no) 2017-01-30
RU2344810C2 (ru) 2009-01-27
US20110212170A1 (en) 2011-09-01
MXPA06003821A (es) 2006-06-14
WO2005048994A1 (en) 2005-06-02
US20100136108A1 (en) 2010-06-03
DE602004013178D1 (de) 2008-05-29
EP1680096B1 (en) 2008-04-16
EP1680096A1 (en) 2006-07-19
CN1874762A (zh) 2006-12-06
SI1680096T1 (sl) 2008-08-31
ATE392204T1 (de) 2008-05-15
US9084824B2 (en) 2015-07-21
ES2303956T3 (es) 2008-09-01
NO20061890L (no) 2006-05-26
RU2006119326A (ru) 2007-12-27
CA2541292C (en) 2010-09-14
US9084823B2 (en) 2015-07-21
NZ546258A (en) 2009-12-24
US20050042278A1 (en) 2005-02-24
PT1680096E (pt) 2008-06-16
JP4555827B2 (ja) 2010-10-06
KR100856362B1 (ko) 2008-09-04
AU2004290494A1 (en) 2005-06-02
BRPI0415634B8 (pt) 2021-05-25
JP2007509890A (ja) 2007-04-19
PL1680096T3 (pl) 2008-09-30
US9399023B2 (en) 2016-07-26
CN100594894C (zh) 2010-03-24
DK1680096T3 (da) 2008-08-04
EP1527774A1 (en) 2005-05-04
US8697122B2 (en) 2014-04-15
US20160367488A1 (en) 2016-12-22
US20150265539A1 (en) 2015-09-24
CA2541292A1 (en) 2005-06-02
BRPI0415634B1 (pt) 2018-12-26
DE602004013178T2 (de) 2009-05-07
CY1108184T1 (el) 2014-02-12
KR20060093721A (ko) 2006-08-25
AU2004290494B2 (en) 2008-06-19
US20140205661A1 (en) 2014-07-24

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25A Requested transfer of rights approved

Owner name: GLAXO GROUP LIMITED (GB)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 26/12/2018, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 28/10/2004 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 21A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2855 DE 23-09-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.