BRPI0416201A - métodos para purificação de toxina coqueluche e peptìdios neles utilizáveis - Google Patents

métodos para purificação de toxina coqueluche e peptìdios neles utilizáveis

Info

Publication number
BRPI0416201A
BRPI0416201A BRPI0416201-3A BRPI0416201A BRPI0416201A BR PI0416201 A BRPI0416201 A BR PI0416201A BR PI0416201 A BRPI0416201 A BR PI0416201A BR PI0416201 A BRPI0416201 A BR PI0416201A
Authority
BR
Brazil
Prior art keywords
purification
methods
pertussis toxin
peptides
usable
Prior art date
Application number
BRPI0416201-3A
Other languages
English (en)
Inventor
Andreas Jungbluth
Eberhard Schneider
Peter Wagner
Original Assignee
Sanofi Pasteur Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur Inc filed Critical Sanofi Pasteur Inc
Publication of BRPI0416201A publication Critical patent/BRPI0416201A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C07K14/003—Peptide-nucleic acids (PNAs)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"MéTODOS PARA PURIFICAçãO DE TOXINA COQUELUCHE E PEPTìDIOS NELES UTILIZáVEIS". A presente invenção se refere a reagentes e métodos para a purificação de toxina Pertussis (PT).
BRPI0416201-3A 2003-11-20 2004-11-18 métodos para purificação de toxina coqueluche e peptìdios neles utilizáveis BRPI0416201A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52388103P 2003-11-20 2003-11-20
PCT/US2004/038700 WO2005051985A2 (en) 2003-11-20 2004-11-18 Methods for purifying pertussis toxin and peptides useful therefor

Publications (1)

Publication Number Publication Date
BRPI0416201A true BRPI0416201A (pt) 2006-12-26

Family

ID=34632841

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0416201-3A BRPI0416201A (pt) 2003-11-20 2004-11-18 métodos para purificação de toxina coqueluche e peptìdios neles utilizáveis

Country Status (11)

Country Link
US (3) US8299210B2 (pt)
EP (1) EP1692313A2 (pt)
JP (2) JP4885729B2 (pt)
KR (2) KR101337320B1 (pt)
CN (1) CN1906307B (pt)
AU (1) AU2004292547B9 (pt)
BR (1) BRPI0416201A (pt)
CA (1) CA2546343A1 (pt)
IL (3) IL175630A (pt)
WO (1) WO2005051985A2 (pt)
ZA (1) ZA200604081B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4885729B2 (ja) 2003-11-20 2012-02-29 サノフィ パストゥール インコーポレイテッド 百日咳毒素を精製する方法およびそれに有用なペプチド
US7749957B2 (en) 2006-04-06 2010-07-06 E.I. Du Pont De Nemours And Company Clay-binding peptides and methods of use
LT2379096T (lt) 2008-12-19 2019-12-27 Baxalta GmbH Tfpi inhibitoriai ir vartojimo būdai
US8962563B2 (en) 2009-12-21 2015-02-24 Baxter International, Inc. TFPI inhibitors and methods of use
EP2430040A1 (en) * 2009-05-11 2012-03-21 Novartis AG Antigen purification process for pertactin antigen
EP2547355B1 (en) 2010-03-19 2017-01-11 Baxalta GmbH Tfpi inhibitors and methods of use
CN105974122B (zh) * 2016-05-04 2018-09-28 华东医药（杭州）基因科技有限公司 一种检测外泌体gpc1蛋白的方法
CN113933438B (zh) * 2021-11-11 2023-11-10 威海华洋药业有限公司 一种紫芪克咳口服液的含量测定方法及制备方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4970162A (en) * 1985-11-13 1990-11-13 The United States Of America As Represented By The Department Of Health And Human Services Human-mouse hybrid cell line expressing monocyte-macrophage properties
US5332583A (en) 1987-11-24 1994-07-26 Connaught Laboratories Limited Vaccine containing genetically-detoxified pertussis holotoxin
GB8727489D0 (en) 1987-11-24 1987-12-23 Connaught Lab Detoxification of pertussis toxin
US5244657A (en) 1987-11-24 1993-09-14 Connaught Laboratories Limited Genetic detoxification of pertussis toxin
US5221618A (en) 1987-11-24 1993-06-22 Connaught Laboratories Limited Genetic detoxification of pertussis toxin
US5358868A (en) 1987-11-24 1994-10-25 Connaught Laboratories Limited Genetic detoxification of pertussis toxin
GB8807860D0 (en) 1988-04-05 1988-05-05 Connaught Lab Pertussis vaccine
US5856122A (en) 1993-08-24 1999-01-05 University Of Alberta Modification of pertussis toxin
US6696065B1 (en) 1995-05-04 2004-02-24 Aventis Pastuer Limited Acellular pertussis vaccines and methods of preparation thereof
CA2433502A1 (en) * 1995-05-04 1996-11-07 Aventis Pasteur Limited Acellular pertussis vaccines and methods of preparation thereof
US5877298A (en) * 1995-05-04 1999-03-02 Connaught Lab Acellular pertussis vaccines and methods of preparing thereof
PT1105360E (pt) 1998-08-17 2009-09-30 Bristol Myers Squibb Co Identificação de interacções entre compostos-proteínas, utilizando bibliotecas de moléculas de fusão entre proteínas-ácidos nucleicos
ATE354675T1 (de) 1998-12-02 2007-03-15 Adnexus Therapeutics Inc Dna-protein fusionen sowie anwendungen derselben
AU779491B2 (en) 1999-06-01 2005-01-27 Bristol-Myers Squibb Company Methods for producing 5'-nucleic acid-protein conjugates
EP1196637B1 (en) 1999-07-27 2007-04-25 Adnexus Therapeutics, Inc. Peptide acceptor ligation methods
JP4803933B2 (ja) 1999-08-27 2011-10-26 ブリストル−マイヤーズ スクウィブ カンパニー インビトロ翻訳タンパク質の符号化方法および選別方法
US7115284B2 (en) * 2003-08-11 2006-10-03 Ayurvedic-Life International, Llc Compositions for diabetes treatment and prophylaxis
JP4885729B2 (ja) 2003-11-20 2012-02-29 サノフィ パストゥール インコーポレイテッド 百日咳毒素を精製する方法およびそれに有用なペプチド
JP2009509535A (ja) * 2005-09-27 2009-03-12 アムニクス， インコーポレイテッド タンパク様薬剤およびその使用
US20080241281A1 (en) * 2007-03-29 2008-10-02 Texas Tech University System Compositions & methods for activation and inhibition of Staphylococcus aureus biofilm development

Also Published As

Publication number Publication date
IL205274A (en) 2013-07-31
IL205274A0 (en) 2011-07-31
JP2011173919A (ja) 2011-09-08
US9145445B2 (en) 2015-09-29
IL205275A0 (en) 2011-07-31
JP4885729B2 (ja) 2012-02-29
AU2004292547B2 (en) 2011-12-22
AU2004292547A1 (en) 2005-06-09
US8299210B2 (en) 2012-10-30
JP5379187B2 (ja) 2013-12-25
ZA200604081B (en) 2007-09-26
WO2005051985A3 (en) 2005-09-29
EP1692313A2 (en) 2006-08-23
US20140187742A1 (en) 2014-07-03
US20090215113A1 (en) 2009-08-27
KR20060129195A (ko) 2006-12-15
IL175630A0 (en) 2006-09-05
KR20120117942A (ko) 2012-10-24
KR101320905B1 (ko) 2013-11-06
HK1099655A1 (en) 2007-08-17
CN1906307A (zh) 2007-01-31
IL205275A (en) 2013-07-31
CA2546343A1 (en) 2005-06-09
JP2008504802A (ja) 2008-02-21
US20160032258A1 (en) 2016-02-04
IL175630A (en) 2015-10-29
CN1906307B (zh) 2011-08-24
AU2004292547B9 (en) 2012-04-26
WO2005051985A2 (en) 2005-06-09
KR101337320B1 (ko) 2013-12-06

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06T Formal requirements before examination [chapter 6.20 patent gazette]
B11E Dismissal acc. art. 34 of ipl - requirements for examination incomplete
B11T Dismissal of application maintained [chapter 11.20 patent gazette]