BRPI0416362A - processo para o cultivo de microorganismos do gênero thraustochytirales - Google Patents

processo para o cultivo de microorganismos do gênero thraustochytirales

Info

Publication number
BRPI0416362A
BRPI0416362A BRPI0416362-1A BRPI0416362A BRPI0416362A BR PI0416362 A BRPI0416362 A BR PI0416362A BR PI0416362 A BRPI0416362 A BR PI0416362A BR PI0416362 A BRPI0416362 A BR PI0416362A
Authority
BR
Brazil
Prior art keywords
microorganisms
caco
thraustochytirales
pufas
fermentation
Prior art date
Application number
BRPI0416362-1A
Other languages
English (en)
Inventor
Markus Luy
Matthias Ruesing
Original Assignee
Nutrinova Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nutrinova Gmbh filed Critical Nutrinova Gmbh
Publication of BRPI0416362A publication Critical patent/BRPI0416362A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434Docosahexenoic acids [DHA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6472Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Edible Oils And Fats (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

"PROCESSO PARA O CULTIVO DE MICROORGANISMOS DO GêNERO THRAUSTOCHYTIRALES". A invenção descreve um processo otimizado para produção de PUFAs, por cultivo de microorganismos da ordem Thraustochytriales em um meio de fermentação de pH estabilizada por carbonato de cálcio, que compreende 3 a 15 g/ilde CaCO~ 3~, e subseqüente isolamento dos PUFAs dos microorganismos e/ou do meio. São descritos, particularmente, novos meios otimizados, com diferentes teores de CaCO~ 3~. O uso de quantidades correspondentes de CaCO~ 3~ permite uma simplificação significativa do processo durante a fermentação. Além disso, podem ser obtidas quantidades maiores de DHA, a um teor de óleo aumentado na biomassa, possibilitando uma fermentação de microorganismos Thraustochytriales sem controle do pH, aperfeiçoando substancialmente e simplificando significativamente a produção de PUFA.
BRPI0416362-1A 2003-11-10 2004-11-10 processo para o cultivo de microorganismos do gênero thraustochytirales BRPI0416362A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10352837A DE10352837A1 (de) 2003-11-10 2003-11-10 Prozess zur Kultivierung von Mikroorganismen der Gattung Thraustochytriales
PCT/EP2004/012715 WO2005045050A1 (de) 2003-11-10 2004-11-10 Prozess zur kultivierung von mikroorganismen der gattung thraustochytrieales

Publications (1)

Publication Number Publication Date
BRPI0416362A true BRPI0416362A (pt) 2007-03-13

Family

ID=34559599

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0416362-1A BRPI0416362A (pt) 2003-11-10 2004-11-10 processo para o cultivo de microorganismos do gênero thraustochytirales

Country Status (17)

Country Link
US (1) US8889382B2 (pt)
EP (1) EP1685255B1 (pt)
JP (1) JP4791366B2 (pt)
KR (1) KR101159869B1 (pt)
CN (2) CN1914327A (pt)
AT (1) ATE556143T1 (pt)
AU (1) AU2004287953B2 (pt)
BR (1) BRPI0416362A (pt)
CA (1) CA2545416C (pt)
DE (1) DE10352837A1 (pt)
EA (1) EA011877B1 (pt)
ES (1) ES2387305T3 (pt)
IL (1) IL175521A (pt)
PL (1) PL1685255T3 (pt)
SG (1) SG148156A1 (pt)
WO (1) WO2005045050A1 (pt)
ZA (1) ZA200603855B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20090092758A (ko) * 2006-09-18 2009-09-01 더 아리조나 보드 오브 리전트스, 어 바디 코포레이트 액팅 포 앤드 온 비핼프 오브 아리조나 스테이트 유니버시티 조류 중쇄 길이 지방산 및 탄화수소
ITMI20061843A1 (it) * 2006-09-27 2008-03-28 Immobiliare G M S R L Formulazioni di medium colturali idonei alla applicazione industriale
US20100086979A1 (en) * 2006-10-27 2010-04-08 Thomas Kiy Production of omega-3 fatty acids in microflora of thraustochytriales using modified media
JP5219390B2 (ja) * 2007-03-19 2013-06-26 学校法人立命館 微生物培養用培地及び微生物製剤
EP2071019A1 (en) * 2007-12-15 2009-06-17 Lonza AG Method for the cultivation of microoranisms of the order thraustochytriales
JP5709196B2 (ja) * 2009-01-09 2015-04-30 国立大学法人山梨大学 油脂生産菌の培養方法
US20110306102A1 (en) * 2009-02-25 2011-12-15 V. B. Medicare Pvt. Ltd. Improved methods for fermentative production of docosahexaenoic acid
AU2012226528B2 (en) * 2011-03-07 2015-08-20 Dsm Nutritional Products Ag Engineering thraustochytrid microorganisms
AP4026A (en) * 2011-07-13 2017-02-04 Alltech Inc Algal lipid compositions and methods of preparing and utilizing the same
CN102911868B (zh) 2012-09-28 2015-12-09 新奥科技发展有限公司 一种微生物培养基及培养方法
KR102236782B1 (ko) * 2014-05-22 2021-04-05 마라 리뉴어블즈 코퍼레이션 미생물에서 오일 생산 방법
CZ307271B6 (cs) 2014-08-26 2018-05-09 Vysoká škola chemicko - technologická v Praze Způsob kultivace mořských protistů, zejména mikroorganismů rodu Thraustochytriales, na médiu obsahujícím odpadní solný roztok z demineralizace sladké mléčné syrovátky

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0113183A1 (en) 1982-12-01 1984-07-11 Thomas Anthony Carson Fermentation method and composition for use therein
JPH01247079A (ja) 1988-03-28 1989-10-02 Nec Corp 培地のpH調整方法
US5407957A (en) 1990-02-13 1995-04-18 Martek Corporation Production of docosahexaenoic acid by dinoflagellates
JPH08196288A (ja) 1995-01-30 1996-08-06 Kaiyo Bio Technol Kenkyusho:Kk 長鎖脂肪酸の製造法
US6582941B1 (en) * 1995-04-17 2003-06-24 Japan As Represented By Director-General Of Agency Of Industrial Science And Technology Microorganisms capable of producing highly unsaturated fatty acids and process for producing highly unsaturated fatty acids by using the microorganisms
JP2764572B2 (ja) * 1995-04-17 1998-06-11 工業技術院長 ドコサヘキサエン酸生産能を有する新規微生物及びそれを用いたドコサヘキサエン酸の製造方法
CA2261231C (en) 1996-07-23 2012-11-27 Nagase Biochemicals, Ltd. Process using ulkenia sp. to prepare docosahexaenoic acid and docosapentaenoic acid

Also Published As

Publication number Publication date
US8889382B2 (en) 2014-11-18
AU2004287953B2 (en) 2010-04-29
IL175521A0 (en) 2006-09-05
CA2545416A1 (en) 2005-05-19
IL175521A (en) 2011-12-29
EP1685255A1 (de) 2006-08-02
CN1914327A (zh) 2007-02-14
JP4791366B2 (ja) 2011-10-12
KR101159869B1 (ko) 2012-06-25
DE10352837A1 (de) 2005-07-07
WO2005045050A1 (de) 2005-05-19
KR20070042114A (ko) 2007-04-20
JP2007512809A (ja) 2007-05-24
AU2004287953A1 (en) 2005-05-19
CA2545416C (en) 2014-02-25
US20070141686A1 (en) 2007-06-21
CN104195186A (zh) 2014-12-10
EA011877B1 (ru) 2009-06-30
ZA200603855B (en) 2007-10-31
ATE556143T1 (de) 2012-05-15
ES2387305T3 (es) 2012-09-20
SG148156A1 (en) 2008-12-31
EP1685255B1 (de) 2012-05-02
EA200600952A1 (ru) 2007-02-27
PL1685255T3 (pl) 2012-12-31

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B11D Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time