BRPI0416590A - excipientes em veìculos de distribuição de fármacos - Google Patents
excipientes em veìculos de distribuição de fármacosInfo
- Publication number
- BRPI0416590A BRPI0416590A BRPI0416590-0A BRPI0416590A BRPI0416590A BR PI0416590 A BRPI0416590 A BR PI0416590A BR PI0416590 A BRPI0416590 A BR PI0416590A BR PI0416590 A BRPI0416590 A BR PI0416590A
- Authority
- BR
- Brazil
- Prior art keywords
- polymers
- excipients
- drug delivery
- delivery vehicles
- gel compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"EXCIPIENTES EM VEìCULOS DE DISTRIBUIçãO DE FáRMACOS". A presente invenção fornece composições de gel injetáveis para depósito e kits que fornecem um excipiente para modular uma taxa de liberação e estabilizar os agente benéficos. São fornecidos também métodos para administrar e preparar tais sistemas. As composições do gel compreendem polímeros biodegradáveis, bioerodíveis, e solventes imiscíveis em água, em quantidades eficazes para plastificar os polímeros e formar géis com os polímeros. Os excipientes apropriados incluem modificadores de pH, agentes redutores e antioxidantes.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51993603P | 2003-11-14 | 2003-11-14 | |
| US10/985,122 US20050106214A1 (en) | 2003-11-14 | 2004-11-10 | Excipients in drug delivery vehicles |
| PCT/US2004/037781 WO2005049069A1 (en) | 2003-11-14 | 2004-11-12 | Excipients in drug delivery vehicles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0416590A true BRPI0416590A (pt) | 2007-01-30 |
Family
ID=34576891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0416590-0A BRPI0416590A (pt) | 2003-11-14 | 2004-11-12 | excipientes em veìculos de distribuição de fármacos |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20050106214A1 (pt) |
| EP (1) | EP1691826A4 (pt) |
| JP (1) | JP4916887B2 (pt) |
| KR (1) | KR20060125749A (pt) |
| AU (2) | AU2004291093A1 (pt) |
| BR (1) | BRPI0416590A (pt) |
| CA (1) | CA2545923A1 (pt) |
| IL (1) | IL175602A0 (pt) |
| MX (1) | MXPA06005463A (pt) |
| NO (1) | NO20062780L (pt) |
| TW (1) | TW200529842A (pt) |
| WO (1) | WO2005049069A1 (pt) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20040058101A (ko) * | 2001-11-14 | 2004-07-03 | 알자 코포레이션 | 카테터 주입가능한 데포 조성물 및 그의 용도 |
| ATE418323T1 (de) * | 2002-11-06 | 2009-01-15 | Alza Corp | Depot-formulierungen mit verzögerter freisetzung |
| US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
| US20050281879A1 (en) * | 2003-11-14 | 2005-12-22 | Guohua Chen | Excipients in drug delivery vehicles |
| WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| US20060252830A1 (en) * | 2005-05-06 | 2006-11-09 | Brandon Stephen F | Method for the treatment of magnesium and potassium deficiencies |
| US20060252831A1 (en) * | 2005-05-06 | 2006-11-09 | Christopher Offen | Method for the treatment of magnesium and potassium deficiencies |
| US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
| EP1912627B1 (en) * | 2005-08-11 | 2016-08-10 | Promedon S.A. | Composition comprising polymeric, water-insoluble, anionic particles, processes and uses |
| US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
| US7261742B2 (en) | 2005-10-13 | 2007-08-28 | S.C. Johnson & Son, Inc. | Method of deodorizing a textile |
| US7407922B2 (en) * | 2005-10-13 | 2008-08-05 | S.C. Johnson & Son, Inc. | Deodorizing compositions |
| MX2008014870A (es) | 2006-05-30 | 2009-02-12 | Intarcia Therapeutics Inc | Modulador de flujo para sistema de suministro osmotico con canal interno de dos piezas. |
| EP1872807A1 (en) * | 2006-06-30 | 2008-01-02 | Scil Technology GmbH | Biomaterial containing degradation stabilized polymer |
| EP2049081B1 (en) | 2006-08-09 | 2012-11-14 | Intarcia Therapeutics, Inc. | Osmotic delivery systems and piston assemblies |
| CA2664341C (en) | 2006-10-05 | 2018-11-06 | Ikaria, Inc. | Liquid chalcogenide compositions and methods of manufacturing and using the same |
| EP2236546B1 (en) * | 2006-10-31 | 2011-12-28 | Surmodics Pharmaceuticals, Inc. | Speronized polymer particles |
| HRP20130259T1 (hr) | 2007-04-23 | 2013-04-30 | Intarcia Therapeutics, Inc. | Suspenzijske formulacije inzulinotropnih peptida i njihove uporabe |
| EP2152315B1 (en) | 2007-05-25 | 2016-01-06 | Indivior UK Limited | Sustained delivery formulations of risperidone compounds |
| DK2240155T3 (da) | 2008-02-13 | 2012-09-17 | Intarcia Therapeutics Inc | Indretninger, formuleringer og fremgangsmåder til levering af flere gavnlige midler |
| SMT201700583T1 (it) | 2009-09-28 | 2018-01-11 | Intarcia Therapeutics Inc | Instaurazione e/o terminazione rapida di erogazione di farmaci in modo sostanzialmente stazionario |
| CN102233129B (zh) * | 2010-04-29 | 2014-07-09 | 上海交通大学 | 一种预防或治疗视网膜损伤的长效缓释制剂及其制备方法 |
| EP2590628A1 (en) * | 2010-06-30 | 2013-05-15 | Evonik Corporation | Implant processing methods for thermally labile and other bioactive agents and implants prepared from same |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| KR101494594B1 (ko) | 2011-08-30 | 2015-02-23 | 주식회사 종근당 | 약리학적 활성물질의 서방성 지질 초기제제 및 이를 포함하는 약제학적 조성물 |
| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| HK1211232A1 (en) | 2012-12-21 | 2016-05-20 | Sanofi | Exendin-4 derivatives as dual glp1/gip or trigonal glp1/gip/glucagon agonists |
| KR101586790B1 (ko) | 2012-12-28 | 2016-01-19 | 주식회사 종근당 | 음이온성 약리학적 활성물질의 서방성 지질 초기제제 및 이를 포함하는 약제학적 조성물 |
| HK1220628A1 (zh) | 2013-03-11 | 2017-05-12 | Durect Corporation | 包含高粘度液体载体的可注射控制释放组合物 |
| US20140308352A1 (en) | 2013-03-11 | 2014-10-16 | Zogenix Inc. | Compositions and methods involving polymer, solvent, and high viscosity liquid carrier material |
| WO2015086728A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Exendin-4 peptide analogues as dual glp-1/gip receptor agonists |
| EP3080152A1 (en) | 2013-12-13 | 2016-10-19 | Sanofi | Non-acylated exendin-4 peptide analogues |
| WO2015086733A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/glucagon receptor agonists |
| TW201609799A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 雙重glp-1/gip受體促效劑 |
| MX386702B (es) | 2014-02-10 | 2025-03-19 | Fred Hutchinson Cancer Center | Tratamiento con halogeno de ataque cardiaco y lesion isquemica. |
| TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物 |
| TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自exendin-4之雙重glp-1/升糖素受體促效劑 |
| TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑 |
| US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
| KR101686986B1 (ko) | 2014-07-28 | 2016-12-16 | 에스케이케미칼주식회사 | 류프로라이드를 포함하는 속효성과 지속성을 동시에 갖는 약제학적 조성물 |
| US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
| NZ731309A (en) | 2014-11-07 | 2022-02-25 | Indivior Uk Ltd | Buprenorphine dosing regimens |
| US10925639B2 (en) | 2015-06-03 | 2021-02-23 | Intarcia Therapeutics, Inc. | Implant placement and removal systems |
| AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
| AR105284A1 (es) | 2015-07-10 | 2017-09-20 | Sanofi Sa | Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón |
| JP7145363B2 (ja) * | 2015-11-23 | 2022-10-03 | グレイス セラピューティクス インコーポレイテッド | 局所皮膜形成スプレー |
| EP3452031A4 (en) * | 2016-05-05 | 2019-12-11 | Liquidia Technologies, Inc. | PRECISION-CONTROLLED LOADING AND RELEASE PARTICLES FOR POST-OPERATIONAL PAIN |
| RU2760007C2 (ru) | 2016-05-16 | 2021-11-22 | Интарсия Терапьютикс, Инк. | Полипептиды, селективные к рецепторам глюкагона, и способы их применения |
| USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| WO2018017696A1 (en) | 2016-07-19 | 2018-01-25 | Ecolab Usa Inc. | Methods and cleaning solutions for removing chewing gum and other sticky food substances |
| CN110225762A (zh) | 2017-01-03 | 2019-09-10 | 因塔西亚制药公司 | 包括glp-1受体激动剂的连续施用和药物的共同施用的方法 |
| US10646484B2 (en) | 2017-06-16 | 2020-05-12 | Indivior Uk Limited | Methods to treat opioid use disorder |
| JP2023515918A (ja) | 2020-01-13 | 2023-04-17 | デュレクト コーポレーション | 不純物が低減された徐放性薬物送達システム及び関連の方法 |
| CN111388744B (zh) * | 2020-01-15 | 2021-05-18 | 华中科技大学 | 一种凝胶贮库及其制法与制备术后止血制剂的应用 |
| CA3203561A1 (en) | 2021-01-12 | 2022-07-21 | Adrian Neil Verity | Sustained release drug delivery systems and related methods |
| CN118201599A (zh) * | 2021-12-24 | 2024-06-14 | 四川科伦药物研究院有限公司 | 一种可平稳释放的持续性递送制剂及其制备方法 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4443340A (en) * | 1981-10-09 | 1984-04-17 | Betz Laboratories, Inc. | Control of iron induced fouling in water systems |
| US4985404A (en) * | 1984-10-04 | 1991-01-15 | Monsanto Company | Prolonged release of biologically active polypeptides |
| US4853218A (en) * | 1987-02-24 | 1989-08-01 | Schering Corporation | Zinc-protamine-alpha interferon complex |
| KR970007322B1 (ko) * | 1991-12-19 | 1997-05-07 | 미쓰이도오아쓰 가가쿠 가부시키가이샤 | 폴리히드록시 카르복실산 및 그 제조방법 |
| US5192743A (en) * | 1992-01-16 | 1993-03-09 | Genentech, Inc. | Reconstitutable lyophilized protein formulation |
| US5656297A (en) * | 1992-03-12 | 1997-08-12 | Alkermes Controlled Therapeutics, Incorporated | Modulated release from biocompatible polymers |
| AU668384B2 (en) * | 1992-03-12 | 1996-05-02 | Alkermes Controlled Therapeutics, Inc. | Controlled release ACTH containing microspheres |
| US5711968A (en) * | 1994-07-25 | 1998-01-27 | Alkermes Controlled Therapeutics, Inc. | Composition and method for the controlled release of metal cation-stabilized interferon |
| US5242910A (en) * | 1992-10-13 | 1993-09-07 | The Procter & Gamble Company | Sustained release compositions for treating periodontal disease |
| WO1994012158A1 (en) * | 1992-12-02 | 1994-06-09 | Alkermes Controlled Therapeutics, Inc. | Controlled release growth hormone containing microspheres |
| US5626862A (en) * | 1994-08-02 | 1997-05-06 | Massachusetts Institute Of Technology | Controlled local delivery of chemotherapeutic agents for treating solid tumors |
| ATE203157T1 (de) * | 1996-12-20 | 2001-08-15 | Alza Corp | Injizierbare depotgelzubereitung und herstellungsverfahren |
| RU2184564C2 (ru) * | 2000-01-28 | 2002-07-10 | Общество С Ограниченной Ответственностью "Ферон" | Лекарственный гель |
| US20030211974A1 (en) * | 2000-03-21 | 2003-11-13 | Brodbeck Kevin J. | Gel composition and methods |
| US6495534B2 (en) * | 2000-05-15 | 2002-12-17 | Pharmacia & Upjohn Spa | Stabilized aqueous suspensions for parenteral use |
| WO2002032398A2 (en) * | 2000-10-16 | 2002-04-25 | Massachusetts Institute Of Technology | Lipid-protein-sugar particles for drug delivery |
| DK1372729T3 (da) * | 2001-02-23 | 2009-06-22 | Genentech Inc | Nedbrydelige polymere til injektion |
| WO2002089849A1 (en) * | 2001-05-07 | 2002-11-14 | Corium International | Compositions and delivery systems for administration of a local anesthetic agent |
| KR20040058101A (ko) * | 2001-11-14 | 2004-07-03 | 알자 코포레이션 | 카테터 주입가능한 데포 조성물 및 그의 용도 |
| EP1446100B1 (en) * | 2001-11-14 | 2011-05-04 | Durect Corporation | Injectable depot compositions and uses thereof |
| US20060083778A1 (en) * | 2002-05-03 | 2006-04-20 | Dean Allison | Controlled release compositions of estradiol metabolites |
| TWI353854B (en) * | 2002-06-25 | 2011-12-11 | Alza Corp | Short duration depot formulations |
| ATE418323T1 (de) * | 2002-11-06 | 2009-01-15 | Alza Corp | Depot-formulierungen mit verzögerter freisetzung |
| US20050281879A1 (en) * | 2003-11-14 | 2005-12-22 | Guohua Chen | Excipients in drug delivery vehicles |
-
2004
- 2004-11-10 US US10/985,122 patent/US20050106214A1/en not_active Abandoned
- 2004-11-12 AU AU2004291093A patent/AU2004291093A1/en not_active Abandoned
- 2004-11-12 TW TW093134557A patent/TW200529842A/zh unknown
- 2004-11-12 CA CA002545923A patent/CA2545923A1/en not_active Abandoned
- 2004-11-12 JP JP2006539893A patent/JP4916887B2/ja not_active Expired - Fee Related
- 2004-11-12 EP EP20040801017 patent/EP1691826A4/en not_active Withdrawn
- 2004-11-12 KR KR1020067009222A patent/KR20060125749A/ko not_active Withdrawn
- 2004-11-12 BR BRPI0416590-0A patent/BRPI0416590A/pt not_active IP Right Cessation
- 2004-11-12 MX MXPA06005463A patent/MXPA06005463A/es active IP Right Grant
- 2004-11-12 WO PCT/US2004/037781 patent/WO2005049069A1/en not_active Ceased
-
2006
- 2006-05-11 IL IL175602A patent/IL175602A0/en unknown
- 2006-06-14 NO NO20062780A patent/NO20062780L/no not_active Application Discontinuation
-
2011
- 2011-04-20 AU AU2011201826A patent/AU2011201826B2/en not_active Ceased
- 2011-12-05 US US13/311,452 patent/US20120177697A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| TW200529842A (en) | 2005-09-16 |
| IL175602A0 (en) | 2006-09-05 |
| EP1691826A1 (en) | 2006-08-23 |
| NO20062780L (no) | 2006-08-14 |
| WO2005049069A1 (en) | 2005-06-02 |
| AU2004291093A1 (en) | 2005-06-02 |
| US20120177697A1 (en) | 2012-07-12 |
| JP4916887B2 (ja) | 2012-04-18 |
| US20050106214A1 (en) | 2005-05-19 |
| AU2011201826A1 (en) | 2011-05-19 |
| EP1691826A4 (en) | 2012-08-22 |
| JP2007511524A (ja) | 2007-05-10 |
| AU2011201826B2 (en) | 2013-06-13 |
| CA2545923A1 (en) | 2005-06-02 |
| MXPA06005463A (es) | 2006-08-11 |
| KR20060125749A (ko) | 2006-12-06 |
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