BRPI0417223A - métodos de preparar compostos úteis como inibidores de protease - Google Patents

métodos de preparar compostos úteis como inibidores de protease

Info

Publication number
BRPI0417223A
BRPI0417223A BRPI0417223-0A BRPI0417223A BRPI0417223A BR PI0417223 A BRPI0417223 A BR PI0417223A BR PI0417223 A BRPI0417223 A BR PI0417223A BR PI0417223 A BRPI0417223 A BR PI0417223A
Authority
BR
Brazil
Prior art keywords
methods
protease inhibitors
compounds useful
preparing compounds
compounds
Prior art date
Application number
BRPI0417223-0A
Other languages
English (en)
Inventor
David John Kucera
Robert William Scott
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BRPI0417223A publication Critical patent/BRPI0417223A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

"MéTODOS DE PREPARAR COMPOSTOS úTEIS COMO INIBIDORES DE PROTEASE". A invenção relaciona-se aos métodos de preparar os compostos de fórmula (I), úteis como inibidores da enzima HIV protease. A presente invenção também se relaciona aos compostos intermediários, úteis na preparação dos compostos de fórmula (I).
BRPI0417223-0A 2003-12-04 2004-11-22 métodos de preparar compostos úteis como inibidores de protease BRPI0417223A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52747703P 2003-12-04 2003-12-04
PCT/IB2004/003823 WO2005054214A1 (en) 2003-12-04 2004-11-22 Methods of preparing compounds useful as protease inhibitors

Publications (1)

Publication Number Publication Date
BRPI0417223A true BRPI0417223A (pt) 2007-03-06

Family

ID=34652496

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0417223-0A BRPI0417223A (pt) 2003-12-04 2004-11-22 métodos de preparar compostos úteis como inibidores de protease

Country Status (6)

Country Link
US (1) US20050124673A1 (pt)
EP (1) EP1692119A1 (pt)
JP (1) JP2007513142A (pt)
BR (1) BRPI0417223A (pt)
CA (1) CA2549290A1 (pt)
WO (1) WO2005054214A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021138694A (ja) 2020-03-06 2021-09-16 ファイザー・インク ＳＡＲＳ−ＣｏＶ−２複製を阻害し、コロナウイルス疾患２０１９を処置する方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6313094B1 (en) * 1990-12-11 2001-11-06 Japan Energy Corporation β-amino-α-hydroxycarboxylic acid derivatives and HIV protease inhibitors
US5644028A (en) * 1992-05-13 1997-07-01 Japan Energy Corporation Process for producing peptide derivatives and salts therefor
NZ248332A (en) * 1992-08-07 1995-01-27 Sankyo Co Hiv protease inhibitor and its use
US6222043B1 (en) * 1995-06-30 2001-04-24 Japan Energy Corporation Methods of preparing novel dipeptide compounds or pharmaceutically acceptable salts thereof
US5932550A (en) * 1995-06-30 1999-08-03 Japan Energy Corporation Dipeptide compound or pharmaceutically acceptable salt thereof and medical use thereof
US6673772B2 (en) * 1999-01-14 2004-01-06 Sumitomo Pharmaceuticals Company Limited Dipeptide compounds and their use as antiviral agents
HN2002000136A (es) * 2001-06-11 2003-07-31 Basf Ag Inhibidores de la proteasa del virus hiv, compuestos que contienen a los mismos, sus usos farmaceuticos y los materiales para su sintesis
US7094909B2 (en) * 2001-06-11 2006-08-22 Agouron Pharmaceuticals, Inc. HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis

Also Published As

Publication number Publication date
US20050124673A1 (en) 2005-06-09
EP1692119A1 (en) 2006-08-23
JP2007513142A (ja) 2007-05-24
CA2549290A1 (en) 2005-06-16
WO2005054214A1 (en) 2005-06-16

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired