BRPI0417350A2 - composiÇço para a distribuiÇço nasal, uso de granisetron ou de um sal farmaceuticamente aceitÁvel do mesmo, e quitosana, um sal, um derivado ou sal de um derivado do mesmo, mÉtodos de administraÇço de granisetron ou de um sal farmaceuticamente aceitÁvel do mesmo, e de tratamento ou prevenÇço de nÁusea e/ou vâmito, e, dispositivo para a distribuiÇço da droga nasal ou um cartucho de dose - Google Patents
composiÇço para a distribuiÇço nasal, uso de granisetron ou de um sal farmaceuticamente aceitÁvel do mesmo, e quitosana, um sal, um derivado ou sal de um derivado do mesmo, mÉtodos de administraÇço de granisetron ou de um sal farmaceuticamente aceitÁvel do mesmo, e de tratamento ou prevenÇço de nÁusea e/ou vâmito, e, dispositivo para a distribuiÇço da droga nasal ou um cartucho de doseInfo
- Publication number
- BRPI0417350A2 BRPI0417350A2 BRPI0417350-3A BRPI0417350A BRPI0417350A2 BR PI0417350 A2 BRPI0417350 A2 BR PI0417350A2 BR PI0417350 A BRPI0417350 A BR PI0417350A BR PI0417350 A2 BRPI0417350 A2 BR PI0417350A2
- Authority
- BR
- Brazil
- Prior art keywords
- salt
- derivative
- granisetron
- pharmaceutically acceptable
- acceptable salt
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 7
- 239000000203 mixture Substances 0.000 title abstract 5
- 229920001661 Chitosan Polymers 0.000 title abstract 3
- MFWNKCLOYSRHCJ-BTTYYORXSA-N granisetron Chemical compound C1=CC=C2C(C(=O)N[C@H]3C[C@H]4CCC[C@@H](C3)N4C)=NN(C)C2=C1 MFWNKCLOYSRHCJ-BTTYYORXSA-N 0.000 title abstract 3
- 229960003727 granisetron Drugs 0.000 title abstract 3
- 206010028813 Nausea Diseases 0.000 title abstract 2
- 206010047700 Vomiting Diseases 0.000 title abstract 2
- 230000008693 nausea Effects 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 230000008673 vomiting Effects 0.000 title abstract 2
- 238000012377 drug delivery Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Otolaryngology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
COMPOSIÇçO PARA A DISTRIBUIÇçO NASAL, USO DE GRAMSETRON OU DE UM SAL FARMACEUTICAMENTE ACEITÁVEL DO MESMO, E QUITOSANA, UM SAL, UM DERIVADO OU UM SAL DE UM DERIVADO DO MESMO, MÉTODOS DE ADMINISTRAÇçO DE GRANISETRON OU DE UM SAL FARMACEUTICAMENTE ACEITÁVEL DO MESMO, E DE TRATAMENTO OU PREVENÇçO DE NÁUSEA E/OU VâMITO, E, DISPOSITIVO PARA A DISTRIBUIÇçO DA DROGA NASAL OU UM CARTUCHO DE DOSE. A presente invenção provê composições para a administração intra-nasal de granisetron ou de um sal farmaceuticamente aceitável do mesmo. Composições preferidas da invenção estão sob a forma de uma solução aquosa. De modo opcional, as composições da invenção compreende quitosano, um sal ou derivado do mesmo ou um sal de um derivado de quitosano. As composições podem ser usadas para o tratamento ou prevenção de náuseas e/ou vômitos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0328186.2A GB0328186D0 (en) | 2003-12-05 | 2003-12-05 | Intranasal compositions |
| PCT/GB2004/005043 WO2005056008A1 (en) | 2003-12-05 | 2004-11-30 | Intranasal compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0417350A2 true BRPI0417350A2 (pt) | 2009-03-10 |
Family
ID=29764615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0417350-3A BRPI0417350A2 (pt) | 2003-12-05 | 2004-11-30 | composiÇço para a distribuiÇço nasal, uso de granisetron ou de um sal farmaceuticamente aceitÁvel do mesmo, e quitosana, um sal, um derivado ou sal de um derivado do mesmo, mÉtodos de administraÇço de granisetron ou de um sal farmaceuticamente aceitÁvel do mesmo, e de tratamento ou prevenÇço de nÁusea e/ou vâmito, e, dispositivo para a distribuiÇço da droga nasal ou um cartucho de dose |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US7947257B2 (pt) |
| EP (1) | EP1696911B1 (pt) |
| JP (1) | JP5103018B2 (pt) |
| KR (1) | KR101194593B1 (pt) |
| CN (2) | CN102389422A (pt) |
| AT (1) | ATE460932T1 (pt) |
| AU (1) | AU2004296586B2 (pt) |
| BR (1) | BRPI0417350A2 (pt) |
| CA (1) | CA2548559C (pt) |
| CY (1) | CY1110664T1 (pt) |
| DE (1) | DE602004026107D1 (pt) |
| DK (1) | DK1696911T3 (pt) |
| ES (1) | ES2357607T3 (pt) |
| GB (1) | GB0328186D0 (pt) |
| HR (1) | HRP20100343T1 (pt) |
| IL (1) | IL176132A (pt) |
| ME (1) | ME01070B (pt) |
| MX (1) | MXPA06006239A (pt) |
| NO (1) | NO335348B1 (pt) |
| NZ (1) | NZ547848A (pt) |
| PL (1) | PL1696911T3 (pt) |
| PT (1) | PT1696911E (pt) |
| RS (1) | RS51251B (pt) |
| SI (1) | SI1696911T1 (pt) |
| WO (1) | WO2005056008A1 (pt) |
| ZA (1) | ZA200604553B (pt) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7638138B2 (en) | 2003-02-21 | 2009-12-29 | Translational Research, Ltd. | Compositions for nasal administration of pharmaceuticals |
| AU2003220808B2 (en) | 2003-03-27 | 2008-08-21 | Bioactis Limited | Powder medicine applicator for nasal cavity |
| WO2006016530A1 (ja) | 2004-08-10 | 2006-02-16 | Translational Research, Ltd. | 速効性でかつ高い吸収性を可能とする経鼻投与用組成物 |
| US7868016B2 (en) * | 2005-07-13 | 2011-01-11 | Baxter International Inc. | Pharmaceutical formulations of endo-N-(9-methyl-9-azabicyclo[3,3.1]non-3-yl)-1-methyl-1H-indazole-3-carboxamide hydrochloride |
| CN101248585B (zh) * | 2005-09-23 | 2011-01-26 | 安费诺凤凰株式会社 | 在便携式电话中使用的滑动式开启和关闭装置 |
| WO2007043057A2 (en) * | 2005-10-11 | 2007-04-19 | Yissum, Research Development Company Of The Hebrew University Of Jerusalem | Compositions for nasal delivery |
| US8337817B2 (en) | 2006-12-26 | 2012-12-25 | Shin Nippon Biomedical Laboratories, Ltd. | Preparation for transnasal application |
| WO2010131486A1 (en) | 2009-05-15 | 2010-11-18 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal pharmaceutical compositions with improved pharmacokinetics |
| WO2011013003A2 (en) * | 2009-07-31 | 2011-02-03 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal granisetron and nasal applicator |
| KR101368587B1 (ko) * | 2010-12-27 | 2014-03-05 | 주식회사 삼양바이오팜 | 오심 또는 구토 방지용 조성물 |
| JP6081102B2 (ja) * | 2012-08-10 | 2017-02-15 | テルモ株式会社 | 安定なグラニセトロン含有水性製剤 |
| US10335398B2 (en) | 2015-04-08 | 2019-07-02 | Maxinase Life Sciences Limited | Bioadhesive compositions for intranasal administration of granisetron |
| JP6905994B2 (ja) * | 2016-01-12 | 2021-07-21 | ノーティック ホールディングス インコーポレイテッド | ベタメタゾン経口スプレー製剤及び運動失調の治療への使用方法 |
| US11744967B2 (en) | 2017-09-26 | 2023-09-05 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal delivery devices |
| GB202301322D0 (en) * | 2023-01-30 | 2023-03-15 | Therakind Ltd | Antiemetic pharmaceutical compositions for nasal delivery |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2004270A1 (en) | 1988-12-29 | 1990-06-29 | William R. Michael | Perfume microcapsules for use in granular detergent compositions |
| CA2042529C (en) | 1990-08-10 | 2002-07-30 | Chokyun Rha | Polysaccharide article and uses therefor |
| US5929059A (en) * | 1991-01-19 | 1999-07-27 | Smithkline Beecham P.L.C. | Pharmaceutical compositions containing granisetron and dexamethasone |
| GB9305593D0 (en) * | 1993-03-18 | 1993-05-05 | Smithkline Beecham Plc | Pharmaceuticals |
| US5897858A (en) * | 1994-02-03 | 1999-04-27 | Schering-Plough Healthcare Products, Inc. | Nasal spray compositions exhibiting increased retention in the nasal cavity |
| GB9406171D0 (en) * | 1994-03-29 | 1994-05-18 | Electrosols Ltd | Dispensing device |
| HRP950149A2 (en) * | 1994-04-13 | 1997-06-30 | Janssen Pharmaceutica Nv | Intranasal antimigrene composition |
| GB9414966D0 (en) | 1994-07-26 | 1994-09-14 | Danbiosyst Uk | Pharmaceutical compositions for the nasal administration of antiviral agents |
| GB9700624D0 (en) | 1997-01-14 | 1997-03-05 | Danbiosyst Uk | Drug delivery composition |
| GB9713980D0 (en) | 1997-07-03 | 1997-09-10 | Danbiosyst Uk | New conjugates |
| US20020132803A1 (en) * | 2001-01-05 | 2002-09-19 | Mahendra Dedhiya | Fluticasone suspension formulation, spray pattern method, and nasal spray apparatus |
| JP2002255795A (ja) * | 2001-02-26 | 2002-09-11 | Teijin Ltd | 経鼻投与用組成物 |
| US20030044356A1 (en) * | 2001-04-20 | 2003-03-06 | Jin Auh | Composition for nasal solution sprays having effective component of 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one) |
| US7666876B2 (en) * | 2002-03-19 | 2010-02-23 | Vernalis (R&D) Limited | Buprenorphine formulations for intranasal delivery |
| CN1332664C (zh) * | 2002-04-26 | 2007-08-22 | 中国人民解放军军事医学科学院毒物药物研究所 | 鼻粉剂 |
| CN1289085C (zh) * | 2002-04-26 | 2006-12-13 | 中国人民解放军军事医学科学院毒物药物研究所 | 鼻腔喷雾剂 |
| GB0329918D0 (en) | 2003-12-24 | 2004-01-28 | West Pharm Serv Drug Res Ltd | Intranasal compositions |
-
2003
- 2003-12-05 GB GBGB0328186.2A patent/GB0328186D0/en not_active Ceased
-
2004
- 2004-11-30 DK DK04798713.6T patent/DK1696911T3/da active
- 2004-11-30 KR KR1020067013467A patent/KR101194593B1/ko not_active Expired - Fee Related
- 2004-11-30 ME MEP-2010-80A patent/ME01070B/me unknown
- 2004-11-30 PT PT04798713T patent/PT1696911E/pt unknown
- 2004-11-30 MX MXPA06006239A patent/MXPA06006239A/es active IP Right Grant
- 2004-11-30 DE DE602004026107T patent/DE602004026107D1/de not_active Expired - Lifetime
- 2004-11-30 HR HR20100343T patent/HRP20100343T1/hr unknown
- 2004-11-30 EP EP04798713A patent/EP1696911B1/en not_active Expired - Lifetime
- 2004-11-30 AU AU2004296586A patent/AU2004296586B2/en not_active Ceased
- 2004-11-30 PL PL04798713T patent/PL1696911T3/pl unknown
- 2004-11-30 AT AT04798713T patent/ATE460932T1/de active
- 2004-11-30 JP JP2006542003A patent/JP5103018B2/ja not_active Expired - Fee Related
- 2004-11-30 CN CN2011102427243A patent/CN102389422A/zh active Pending
- 2004-11-30 ES ES04798713T patent/ES2357607T3/es not_active Expired - Lifetime
- 2004-11-30 NZ NZ547848A patent/NZ547848A/en not_active IP Right Cessation
- 2004-11-30 SI SI200431395T patent/SI1696911T1/sl unknown
- 2004-11-30 CA CA2548559A patent/CA2548559C/en not_active Expired - Fee Related
- 2004-11-30 WO PCT/GB2004/005043 patent/WO2005056008A1/en not_active Ceased
- 2004-11-30 BR BRPI0417350-3A patent/BRPI0417350A2/pt not_active Application Discontinuation
- 2004-11-30 RS RSP-2010/0211A patent/RS51251B/sr unknown
- 2004-11-30 CN CNA2004800398583A patent/CN1901905A/zh active Pending
- 2004-12-03 US US11/004,556 patent/US7947257B2/en not_active Expired - Fee Related
-
2006
- 2006-06-02 ZA ZA200604553A patent/ZA200604553B/xx unknown
- 2006-06-02 NO NO20062548A patent/NO335348B1/no not_active IP Right Cessation
- 2006-06-05 IL IL176132A patent/IL176132A/en not_active IP Right Cessation
-
2010
- 2010-06-11 CY CY20101100528T patent/CY1110664T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8, 10, 13 E 25 DA LPI |
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| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |