BRPI0417829A - composições e processos para tratamento da diabetes - Google Patents
composições e processos para tratamento da diabetesInfo
- Publication number
- BRPI0417829A BRPI0417829A BRPI0417829-7A BRPI0417829A BRPI0417829A BR PI0417829 A BRPI0417829 A BR PI0417829A BR PI0417829 A BRPI0417829 A BR PI0417829A BR PI0417829 A BRPI0417829 A BR PI0417829A
- Authority
- BR
- Brazil
- Prior art keywords
- diabetes
- processes
- prevent
- preferred
- treatment compositions
- Prior art date
Links
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 8
- 239000000203 mixture Substances 0.000 title abstract 4
- OGMADIBCHLQMIP-UHFFFAOYSA-N 2-aminoethanethiol;hydron;chloride Chemical compound Cl.NCCS OGMADIBCHLQMIP-UHFFFAOYSA-N 0.000 abstract 1
- 206010022489 Insulin Resistance Diseases 0.000 abstract 1
- -1 cysteamine compound Chemical class 0.000 abstract 1
- 229940097265 cysteamine hydrochloride Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000004153 glucose metabolism Effects 0.000 abstract 1
- 229960003151 mercaptamine Drugs 0.000 abstract 1
- XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 abstract 1
- 229960003105 metformin Drugs 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
Abstract
"COMPOSIçõES E PROCESSOS PARA TRATAMENTO DA DIABETES". A presente invenção fornece composições e métodos para o tratamento de diabetes em pacientes. Em uma modalidade preferida, a invenção fornece processos de composição para o tratamento de diabetes e/ou de prevenção ou alívio das complicações associadas com o diabetes. é especificamente exemplificada aqui a administração concorrente de um composto de cisteamina com pelo menos um agente terapêutico adicional para prevenir e/ou tratar o diabetes assim como prevenir elou tratar as complicações associadas com o diabetes. Em uma modalidade preferida, a administração oral de cloridrato de cisteamina com Metformin a um paciente diagnosticado com diabetes pode regular de forma substancial o metabolismo da glicose e a sensibilidade à insulina do paciente.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53111903P | 2003-12-19 | 2003-12-19 | |
| US59170904P | 2004-07-27 | 2004-07-27 | |
| PCT/US2004/042884 WO2005063226A1 (en) | 2003-12-19 | 2004-12-20 | Compositions and methods for treating diabetes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0417829A true BRPI0417829A (pt) | 2007-04-10 |
Family
ID=34742984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0417829-7A BRPI0417829A (pt) | 2003-12-19 | 2004-12-20 | composições e processos para tratamento da diabetes |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US7442720B2 (pt) |
| EP (1) | EP1696897B1 (pt) |
| JP (1) | JP4845740B2 (pt) |
| KR (1) | KR101329369B1 (pt) |
| CN (1) | CN101897970A (pt) |
| AR (1) | AR047779A1 (pt) |
| AT (1) | ATE515261T1 (pt) |
| AU (1) | AU2004308934B2 (pt) |
| BR (1) | BRPI0417829A (pt) |
| CA (1) | CA2549717C (pt) |
| IL (1) | IL176259A (pt) |
| MX (1) | MXPA06007100A (pt) |
| MY (1) | MY143799A (pt) |
| RU (1) | RU2367423C2 (pt) |
| SG (1) | SG149814A1 (pt) |
| TW (1) | TWI350751B (pt) |
| WO (1) | WO2005063226A1 (pt) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7785627B2 (en) | 2002-09-20 | 2010-08-31 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| US7959946B2 (en) | 2002-09-20 | 2011-06-14 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| US9060941B2 (en) | 2002-09-20 | 2015-06-23 | Actavis, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| US8084058B2 (en) | 2002-09-20 | 2011-12-27 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| WO2005049002A1 (en) | 2003-11-19 | 2005-06-02 | Omega Bio-Pharma International Ltd. | Materials and methods for improving alcohol metabolism and alleviating the effects of hangovers |
| US20050143473A1 (en) * | 2003-12-19 | 2005-06-30 | Wong Gary K.P. | Methods for treating allergy |
| SG149814A1 (en) * | 2003-12-19 | 2009-02-27 | Omega Bio Pharma Ip3 Ltd | Compositions and methods for treating diabetes |
| EP1706104A2 (en) * | 2004-01-13 | 2006-10-04 | Omega Bio-Pharma (I.P.2) Limited | Methods for treating stress and affecting biological immune systems using a cysteamine compound |
| MXPA06012752A (es) * | 2004-05-03 | 2007-02-14 | Omega Bio Pharma Ip3 Ltd | Cisteaminas para tratar complicaciones de hipercolesterolemia y diabetes. |
| DE602005010079D1 (de) * | 2004-06-30 | 2008-11-13 | Walcom Animal Science I P 3 Lt | Undheit, der immunität und des wachstums bei schalentieren |
| US20070172514A1 (en) * | 2006-01-20 | 2007-07-26 | Francis Chi | Materials and methods for improving livestock productivity |
| PT1919458E (pt) | 2006-01-27 | 2012-08-23 | Univ California | Cisteamina revestida entericamente, cisteamina e seus derivados |
| AU2013267044B2 (en) * | 2006-01-27 | 2016-07-07 | The Regents Of The University Of California | Enterically coated cysteamine, cystamine and derivatives thereof |
| US8138227B2 (en) * | 2006-07-06 | 2012-03-20 | Trustees Of Dartmouth College | Method for inhibiting or reversing non-enzymatic glycation |
| US7993687B2 (en) | 2006-07-12 | 2011-08-09 | Julianne Marie Kawa | Compositions and methods for management of diabetes |
| EA020870B1 (ru) | 2007-07-19 | 2015-02-27 | Такеда Фармасьютикал Компани Лимитед | Твердый препарат, включающий алоглиптин и гидрохлорид метформина |
| HRP20130590T1 (en) | 2007-11-30 | 2013-08-31 | The Regents Of The University Of California | Methods of treating non-alcoholic steatohepatitis (nash) using cysteamine products |
| TR201902542T4 (tr) * | 2010-04-13 | 2019-03-21 | M Lab Gmbh | Glokom i̇çi̇n tani yöntemleri̇ |
| WO2011130719A2 (en) | 2010-04-15 | 2011-10-20 | The Regents Of The University Of Michigan | A biosynthetic pathway for heterologous expression of a nonribosomal peptide synthetase drug and analogs |
| GB201021186D0 (en) | 2010-12-14 | 2011-01-26 | Novabiotics Ltd | Composition |
| US11759441B2 (en) | 2011-01-07 | 2023-09-19 | Anji Pharmaceuticals Inc. | Biguanide compositions and methods of treating metabolic disorders |
| US9480663B2 (en) * | 2011-01-07 | 2016-11-01 | Elcelyx Therapeutics, Inc. | Biguanide compositions and methods of treating metabolic disorders |
| US9572784B2 (en) | 2011-01-07 | 2017-02-21 | Elcelyx Therapeutics, Inc. | Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk |
| EP2661266B1 (en) | 2011-01-07 | 2020-09-16 | Anji Pharma (US) LLC | Chemosensory receptor ligand-based therapies |
| US9211263B2 (en) | 2012-01-06 | 2015-12-15 | Elcelyx Therapeutics, Inc. | Compositions and methods of treating metabolic disorders |
| US11974971B2 (en) | 2011-01-07 | 2024-05-07 | Anji Pharmaceuticals Inc. | Compositions and methods for treating metabolic disorders |
| US8796338B2 (en) | 2011-01-07 | 2014-08-05 | Elcelyx Therapeutics, Inc | Biguanide compositions and methods of treating metabolic disorders |
| AU2012213435B2 (en) * | 2011-02-02 | 2017-03-30 | Sanofi-Aventis Deutschland Gmbh | Prevention of hypoglycaemia in diabetes mellitus type 2 patients |
| RU2638807C2 (ru) * | 2011-11-22 | 2017-12-15 | Те Риджентс Оф Те Юниверсити Оф Калифорния | Способы и композиции для лечения воспаления и ишемического поражения |
| KR20190120430A (ko) | 2012-01-06 | 2019-10-23 | 엘셀릭스 테라퓨틱스 인코포레이티드 | 바이구아나이드 조성물 및 대사 장애를 치료하는 방법 |
| EP2800562A2 (en) | 2012-01-06 | 2014-11-12 | Elcelyx Therapeutics, Inc. | Compositions and methods for treating metabolic disorders |
| US20140314841A1 (en) | 2013-04-19 | 2014-10-23 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv | Use of Cysteamine and Derivatives Thereof to Suppress Tumor Metastases |
| TWI649100B (zh) | 2013-06-17 | 2019-02-01 | 地平線罕見醫學製藥有限責任公司 | 延遲釋放型半胱胺珠粒調配物,以及其製備及使用方法 |
| WO2015015403A2 (en) * | 2013-08-01 | 2015-02-05 | Mahesh Kandula | Compositions and methods for the treatment of diabetes and pre-diabetes |
| AU2015312134A1 (en) * | 2014-09-02 | 2017-03-23 | Bhupinder Singh | Deuterated or a non-deuterated molecule and pharmaceutical formulations |
| GB201416716D0 (en) * | 2014-09-22 | 2014-11-05 | Novabiotics Ltd | Use |
| EP3316877B1 (en) | 2015-07-02 | 2019-10-30 | Horizon Orphan LLC | Ado-resistant cysteamine analogs and uses thereof |
| CN108289899A (zh) * | 2015-09-22 | 2018-07-17 | 维京治疗公司 | 采用葡萄糖生成的抑制剂的联合疗法 |
| WO2017062363A1 (en) * | 2015-10-05 | 2017-04-13 | Joslin Diabetes Center | Methods of use of betatrophin |
| CN106620715B (zh) * | 2015-11-04 | 2021-04-06 | 江苏恒瑞医药股份有限公司 | 一种治疗糖尿病的药物组合物及其制备方法 |
| WO2017087532A1 (en) | 2015-11-16 | 2017-05-26 | The Regents Of The University Of California | Methods of treating non-alcoholic steatohepatitis (nash) using cysteamine compounds |
| US10143665B2 (en) | 2015-11-17 | 2018-12-04 | Horizon Orphan Llc | Methods for storing cysteamine formulations and related methods of treatment |
| US10155948B2 (en) | 2016-05-12 | 2018-12-18 | Kangwon National University University-Industry Cooperation Foundation and | Pharmaceutical composition for preventing or treating diabetic complications and screening method for preventive or therapeutic agent for diabetic complications |
| KR101881662B1 (ko) * | 2016-05-12 | 2018-07-26 | 강원대학교산학협력단 | 당뇨성 합병증 예방 및 치료용 약제학적 조성물 및 당뇨성 합병증 예방 또는 치료제 스크리닝 방법 |
| CA3050119A1 (en) * | 2017-01-25 | 2018-08-02 | Adare Pharmaceuticals, Inc. | Cysteamine prodrugs |
| CN109439553B (zh) * | 2018-12-26 | 2020-08-21 | 华熙生物科技股份有限公司 | 产麦角硫因的菌株及其筛选方法 |
| WO2025179209A1 (en) * | 2024-02-22 | 2025-08-28 | Whitehead Institute For Biomedical Research | Methods and agents to study and restore suppressed protein mobility in disease |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4062950A (en) * | 1973-09-22 | 1977-12-13 | Bayer Aktiengesellschaft | Amino sugar derivatives |
| DE3343141A1 (de) * | 1983-11-29 | 1985-06-05 | Hermann P.T. 7400 Tübingen Ammon | Verwendung von cystein-derivaten oder deren salzen, zur steigerung der insulinsekretion der langerhans'schen inseln der bauchspeicheldruese |
| WO1988009660A2 (en) | 1987-06-04 | 1988-12-15 | Massachusetts Institute Of Technology | Chemical prevention or reversal of cataract by phase separation inhibitors |
| US5401880A (en) | 1987-06-04 | 1995-03-28 | Oculon Corporation | Chemical prevention or reversal of cataract by phase separation inhibitors |
| US6746678B1 (en) | 1991-02-22 | 2004-06-08 | Howard K. Shapiro | Method of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with medicaments |
| US5668117A (en) | 1991-02-22 | 1997-09-16 | Shapiro; Howard K. | Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments |
| ZA949715B (en) | 1993-12-14 | 1996-06-06 | Lilly Co Eli | Aqueous solution inclusion complexes of benzothiophene compounds with water soluble cyclodextrins and pharmaceutical formulations and methods thereof |
| FR2716625B1 (fr) * | 1994-02-25 | 1996-04-26 | Gouchet Franck Arno | Préparation et utilisation de formes pharmaceutiques et cosmétiques contenant des composés d'inclusion avec les cyclodextrines de cystéamine, sels de cystéamine, ou dérivés de la cystéamine, sous forme de sel ou non. |
| US5714519A (en) | 1995-06-07 | 1998-02-03 | Ergo Science Incorporated | Method for regulating glucose metabolism |
| KR100245077B1 (ko) * | 1997-04-25 | 2000-02-15 | 김영환 | 반도체 메모리 소자의 딜레이 루프 럭크 회로 |
| US6100736A (en) * | 1997-06-05 | 2000-08-08 | Cirrus Logic, Inc | Frequency doubler using digital delay lock loop |
| FR2774591B1 (fr) * | 1998-02-12 | 2000-05-05 | Lipha | Composition pharmaceutique comprenant l'association metformine et fibrate et son utilisation pour la preparation de medicaments destines a reduire l'hyperglycemie |
| US6621496B1 (en) * | 1999-02-26 | 2003-09-16 | Micron Technology, Inc. | Dual mode DDR SDRAM/SGRAM |
| US6521266B1 (en) | 1999-09-23 | 2003-02-18 | Morris A. Mann | Composition for growth hormone production and release, appetite suppression, and methods related thereto |
| BR0015294A (pt) * | 1999-11-03 | 2003-07-15 | Bristol Myers Squibb Co | Método para tratamento da diabetes |
| US6630176B2 (en) | 2000-03-07 | 2003-10-07 | Mount Sinai School Of Medicine Of New York University | Herbal remedies for treating allergies and asthma |
| AU6118001A (en) * | 2000-05-03 | 2001-11-12 | Tularik Inc | Combination therapeutic compositions and methods of use |
| AU2001266861A1 (en) | 2000-06-12 | 2001-12-24 | Randell L. Mills | Photocleavable prodrugs for selective drug delivery |
| CN1144585C (zh) | 2000-12-13 | 2004-04-07 | 华扩达动物科学[I.P.2]有限公司 | 含有半胱胺或其盐类的促进动物快速生长的组合物及用途 |
| JP3715529B2 (ja) | 2000-12-19 | 2005-11-09 | 雅嗣 田中 | アルコール代謝促進剤 |
| US6746578B2 (en) * | 2001-05-31 | 2004-06-08 | International Business Machines Corporation | Selective shield/material flow mechanism |
| EP1558244A2 (en) * | 2002-11-07 | 2005-08-03 | DSM IP Assets B.V. | Novel nutraceutical compositions comprising epigallocatechin gallate |
| US8017651B2 (en) | 2002-11-22 | 2011-09-13 | Bionexus, Ltd. | Compositions and methods for the treatment of HIV-associated fat maldistribution and hyperlipidemia |
| WO2005049002A1 (en) | 2003-11-19 | 2005-06-02 | Omega Bio-Pharma International Ltd. | Materials and methods for improving alcohol metabolism and alleviating the effects of hangovers |
| SG149814A1 (en) * | 2003-12-19 | 2009-02-27 | Omega Bio Pharma Ip3 Ltd | Compositions and methods for treating diabetes |
| US20050143473A1 (en) | 2003-12-19 | 2005-06-30 | Wong Gary K.P. | Methods for treating allergy |
| MXPA06012752A (es) * | 2004-05-03 | 2007-02-14 | Omega Bio Pharma Ip3 Ltd | Cisteaminas para tratar complicaciones de hipercolesterolemia y diabetes. |
-
2004
- 2004-12-20 SG SG200809465-8A patent/SG149814A1/en unknown
- 2004-12-20 BR BRPI0417829-7A patent/BRPI0417829A/pt not_active IP Right Cessation
- 2004-12-20 JP JP2006545568A patent/JP4845740B2/ja not_active Expired - Fee Related
- 2004-12-20 US US11/017,164 patent/US7442720B2/en not_active Expired - Fee Related
- 2004-12-20 TW TW093139597A patent/TWI350751B/zh not_active IP Right Cessation
- 2004-12-20 AT AT04815013T patent/ATE515261T1/de not_active IP Right Cessation
- 2004-12-20 EP EP04815013A patent/EP1696897B1/en not_active Expired - Lifetime
- 2004-12-20 RU RU2006126062/14A patent/RU2367423C2/ru not_active IP Right Cessation
- 2004-12-20 KR KR1020067013737A patent/KR101329369B1/ko not_active Expired - Fee Related
- 2004-12-20 CN CN2010102231017A patent/CN101897970A/zh active Pending
- 2004-12-20 AU AU2004308934A patent/AU2004308934B2/en not_active Ceased
- 2004-12-20 WO PCT/US2004/042884 patent/WO2005063226A1/en not_active Ceased
- 2004-12-20 AR ARP040104812A patent/AR047779A1/es unknown
- 2004-12-20 MY MYPI20045235A patent/MY143799A/en unknown
- 2004-12-20 CA CA2549717A patent/CA2549717C/en not_active Expired - Fee Related
- 2004-12-20 MX MXPA06007100A patent/MXPA06007100A/es active IP Right Grant
-
2006
- 2006-06-12 IL IL176259A patent/IL176259A/en not_active IP Right Cessation
-
2008
- 2008-10-28 US US12/259,721 patent/US8188151B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20050137125A1 (en) | 2005-06-23 |
| US7442720B2 (en) | 2008-10-28 |
| HK1099507A1 (en) | 2007-08-17 |
| AR047779A1 (es) | 2006-02-22 |
| IL176259A (en) | 2016-02-29 |
| MY143799A (en) | 2011-07-15 |
| EP1696897A1 (en) | 2006-09-06 |
| AU2004308934B2 (en) | 2010-04-01 |
| MXPA06007100A (es) | 2007-01-19 |
| WO2005063226A1 (en) | 2005-07-14 |
| IL176259A0 (en) | 2006-10-05 |
| JP2007514771A (ja) | 2007-06-07 |
| TWI350751B (en) | 2011-10-21 |
| CA2549717C (en) | 2012-11-13 |
| RU2367423C2 (ru) | 2009-09-20 |
| CN101897970A (zh) | 2010-12-01 |
| ATE515261T1 (de) | 2011-07-15 |
| CA2549717A1 (en) | 2005-07-14 |
| KR101329369B1 (ko) | 2013-11-14 |
| KR20070004569A (ko) | 2007-01-09 |
| TW200524583A (en) | 2005-08-01 |
| RU2006126062A (ru) | 2008-01-27 |
| AU2004308934A1 (en) | 2005-07-14 |
| US8188151B2 (en) | 2012-05-29 |
| US20090048154A1 (en) | 2009-02-19 |
| SG149814A1 (en) | 2009-02-27 |
| JP4845740B2 (ja) | 2011-12-28 |
| EP1696897B1 (en) | 2011-07-06 |
| EP1696897A4 (en) | 2008-12-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI0417829A (pt) | composições e processos para tratamento da diabetes | |
| Bigat et al. | Does dexamethasone improve the quality of intravenous regional anesthesia and analgesia? A randomized, controlled clinical study | |
| BR0015295A (pt) | Formulação e método antidiabético | |
| Quickfall et al. | Pathological gambling associated with dopamine agonist use in restless legs syndrome | |
| Orrell | Motor neuron disease: systematic reviews of treatment for ALS and SMA | |
| ATE432289T1 (de) | Glp-1 und behandlungsmethode für diabetes | |
| BR0015974A (pt) | Uso de levetiracetam, composição farmacêutica, uso de uma composição farmacêutica e métodos para tratar um paciente admintstrado com uma quantidade de pelo menos um composto e uma doença e para potenciar seletivamente o efeito terapêutico de um composto | |
| WO2009021521A3 (en) | Use of gaboxadol for the manufacture of a medicament for treating stress-mediated depression | |
| BRPI0804623B8 (pt) | uso de albumina humana terapêutica para a preparação de um fármaco para o tratamento de pacientes sofrendo de distúrbios cognitivos | |
| BR0315573A (pt) | Método para tratar, prevenir, controlar e/ou modificar dor em um paciente e composição farmacêutica | |
| WO2005039554A3 (en) | Therapeutic use of methionine for the treatment or prevention of mucositis | |
| Alessandrini et al. | Intralesional steroid treatment for the intermediate stage of retronychia: a pilot study | |
| BR112012020185A2 (pt) | uso de preparações de heparina oral para tratar doenças e afecções do trato urinário. | |
| BR0314617A (pt) | Método para cardioproteção e neuroproteção por administração intravenosa de anestésico voláteis halogenados | |
| MX2008001520A (es) | Composiciones de tizanidina y metodos de tratamiento usando las composiciones. | |
| BRPI0414518A (pt) | composições farmacêuticas e métodos compreendendo combinações de derivados de 2-alquilideno-19-nor-vitamina d e hormÈnio paratireoidiano | |
| LUDWIG et al. | Ochronosis from quinacrine (atabrine) | |
| Joshi et al. | Designer insulins regimens in clinical practice-pilot multicenter indian study | |
| CA2516458A1 (en) | Use of kahalalide compounds for the manufacture of a medicament for the treatment of psoriasis | |
| BR0111464A (pt) | Composição farmacêutica na forma de dosagem unitária, e, método de tratamento de um paciente com nefropatia diabética | |
| RU2222319C2 (ru) | Способ регионарной лимфостимуляции и обезболивания при лимфедеме нижних конечностей | |
| Ali et al. | The Effect of Ketamine-Propofol Administration versus Propofol on Hemodynamic Stability during Induction and Intubation and Maintenance of Anesthesia | |
| US12005068B2 (en) | Formulation including doxycycline hyclate and method for administering the same | |
| BRPI0519036A2 (pt) | mÉtodo para o tratamento de um paciente acometido por uma doenÇa neuro-degenerativa; composiÇço farmacÊutica para tratar uma doenÇa neuro-degenerativa; e uso de um agonista 5-ht6 ou de um agonista 5-ht6 | |
| BR112022017942A2 (pt) | Composição farmacêutica para prevenção ou tratamento de diabetes e doenças metabólicas associadas à mesma |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Free format text: PARA INT.CL: A61K 31/16, A61K 31/155, A61K 31/13, A61P 3/00 Ipc: A61K 31/16 (2011.01), A61K 31/155 (2011.01), A61K |
|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |