BRPI0417932A - lipólise medicamentosa de acúmulo de gordura - Google Patents
lipólise medicamentosa de acúmulo de gorduraInfo
- Publication number
- BRPI0417932A BRPI0417932A BRPI0417932-3A BRPI0417932A BRPI0417932A BR PI0417932 A BRPI0417932 A BR PI0417932A BR PI0417932 A BRPI0417932 A BR PI0417932A BR PI0417932 A BRPI0417932 A BR PI0417932A
- Authority
- BR
- Brazil
- Prior art keywords
- fat accumulation
- lipolysis
- accumulation drug
- drug
- fat
- Prior art date
Links
- 238000009825 accumulation Methods 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 230000004130 lipolysis Effects 0.000 title abstract 2
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 abstract 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 abstract 1
- 239000003613 bile acid Substances 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 230000037213 diet Effects 0.000 abstract 1
- 235000005911 diet Nutrition 0.000 abstract 1
- 150000003904 phospholipids Chemical group 0.000 abstract 1
- 229960002477 riboflavin Drugs 0.000 abstract 1
- 235000019192 riboflavin Nutrition 0.000 abstract 1
- 239000002151 riboflavin Substances 0.000 abstract 1
- 210000004003 subcutaneous fat Anatomy 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/413—Gall bladder; Bile
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/06—Preparations for care of the skin for countering cellulitis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nutrition Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Child & Adolescent Psychology (AREA)
- Physiology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
"LIPóLISE MEDICAMENTOSA DE ACúMULO DE GORDURA". A presente invenção refere-se a preparações aquosas contendo pelo menos um fosfolipídio e/ou pelo menos um ácido biliar e um componente que auxilia a decomposição de gordura, como riboflavina e água, são apropriadas para preparação de medicamentos para eliminação de acúmulo subcutâneo de gordura e levam à regressão de panículo adiposo resistentes a dietas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10361067A DE10361067A1 (de) | 2003-12-22 | 2003-12-22 | Medikamentöse Lipolyse von Fettansammlungen |
| PCT/EP2004/014134 WO2005063169A2 (de) | 2003-12-22 | 2004-12-11 | Medikamentöse lipolyse von fettansammlungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0417932A true BRPI0417932A (pt) | 2007-04-17 |
Family
ID=34673059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0417932-3A BRPI0417932A (pt) | 2003-12-22 | 2004-12-11 | lipólise medicamentosa de acúmulo de gordura |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1699490A2 (pt) |
| JP (1) | JP2007515439A (pt) |
| KR (1) | KR20060121238A (pt) |
| CN (1) | CN1897974A (pt) |
| AU (1) | AU2004308072A1 (pt) |
| BR (1) | BRPI0417932A (pt) |
| CA (1) | CA2551474A1 (pt) |
| DE (1) | DE10361067A1 (pt) |
| IL (1) | IL176026A0 (pt) |
| MX (1) | MXPA06006645A (pt) |
| WO (1) | WO2005063169A2 (pt) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA06013437A (es) * | 2004-05-19 | 2007-03-23 | Los Angeles Biomed Res Inst | Uso de un detergente para la eliminacion no quirurgica de grasa. |
| US20060127468A1 (en) | 2004-05-19 | 2006-06-15 | Kolodney Michael S | Methods and related compositions for reduction of fat and skin tightening |
| US7754230B2 (en) * | 2004-05-19 | 2010-07-13 | The Regents Of The University Of California | Methods and related compositions for reduction of fat |
| PT1845938T (pt) * | 2005-02-08 | 2019-07-11 | Univ California | Métodos e composições relacionadas para redução da gordura e para refirmar a pele |
| DE102007015701A1 (de) | 2007-03-19 | 2008-09-25 | Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh | Neue pharmazeutische Zusammensetzungen für die Lipolyse und Verfahren zu deren Herstellung |
| FR2937554B1 (fr) * | 2008-10-27 | 2010-11-12 | Yves Crassas | Solutions salines aqueuses pour la destruction de tissus graisseux |
| KR20120104487A (ko) * | 2009-03-02 | 2012-09-21 | 도리스 헥스셀 | 의료용 미용 지방수축 |
| US8101593B2 (en) | 2009-03-03 | 2012-01-24 | Kythera Biopharmaceuticals, Inc. | Formulations of deoxycholic acid and salts thereof |
| CN102481305B (zh) | 2009-08-25 | 2015-08-19 | 美德阿利克斯株式会社 | 磷脂酰胆碱的经皮组合物及其制备方法 |
| DE102010028365A1 (de) | 2010-04-29 | 2011-11-03 | Lichtblick Gmbh | Verwendung einer Phospholipid enthaltenden Zusammensetzung zur Entfernung von subkutanen Fettansammlungen |
| MX363465B (es) | 2011-02-18 | 2019-03-25 | Kythera Biopharmaceuticals Inc | Tratamiento de la grasa submental. |
| US8653058B2 (en) | 2011-04-05 | 2014-02-18 | Kythera Biopharmaceuticals, Inc. | Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits |
| AU2011375432B2 (en) * | 2011-08-23 | 2016-02-04 | Kythera Biopharmaceuticals, Inc. | Formulations of deoxycholic acid and salts thereof |
| CN114469959A (zh) * | 2014-03-21 | 2022-05-13 | 雀巢产品有限公司 | 对母亲施用维生素b2预防后代发胖、超重或肥胖的增加 |
| US11298314B2 (en) * | 2017-04-21 | 2022-04-12 | Ami Pharm Co., Ltd. | Injectable composition for localized fat reduction without pain, edema, and side effects, and method for preparing same |
| KR102093872B1 (ko) * | 2017-07-03 | 2020-03-27 | 진호성 | 지방제거용 주사제 조성물 및 이의 제조방법 |
| JP6356329B2 (ja) * | 2017-09-27 | 2018-07-11 | キテラ バイオファーマシューティカルズ,インコーポレイテッド | デオキシコール酸およびその塩類の製剤 |
| KR101865562B1 (ko) * | 2017-11-03 | 2018-06-08 | 주식회사 펜믹스 | 포스포콜린 유도체를 포함하는 지방분해 조성물 |
| KR20190095833A (ko) * | 2018-02-07 | 2019-08-16 | 이기택 | 고통 및 부작용이 없는 국소지방 감소용 포스파티딜콜린 비포함 주사제 조성물 |
| CN110302082A (zh) * | 2018-03-27 | 2019-10-08 | 上海同柏生物科技有限公司 | 用于减少身体脂肪沉积的技术及组合物制剂与应用 |
| CN109674696A (zh) * | 2018-03-27 | 2019-04-26 | 上海同柏生物科技有限公司 | 一种用于腹部脂肪降解技术及其制剂与应用 |
| KR102939043B1 (ko) | 2020-06-01 | 2026-03-16 | 코스메드 파마소티컬 씨오 쩜 엘티디 | 미용용 마이크로니들 어레이 |
| WO2022019187A1 (ja) * | 2020-07-20 | 2022-01-27 | コスメディ製薬株式会社 | 美容用外用剤及び化粧料 |
| KR102513115B1 (ko) * | 2020-12-18 | 2023-03-22 | 주식회사 레시텍 | 리토콜릭산을 포함하는 국소지방 감소용 조성물 |
| KR102691705B1 (ko) * | 2021-10-25 | 2024-08-06 | 주식회사 지엘케이인터내셔날 | 지방 분해용 조성물 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10349979B4 (de) * | 2003-10-24 | 2006-05-18 | Sanofi-Aventis Deutschland Gmbh | Medikamentöse gezielte lokale Lipolyse |
-
2003
- 2003-12-22 DE DE10361067A patent/DE10361067A1/de not_active Withdrawn
-
2004
- 2004-12-11 EP EP04803773A patent/EP1699490A2/de not_active Ceased
- 2004-12-11 AU AU2004308072A patent/AU2004308072A1/en not_active Abandoned
- 2004-12-11 BR BRPI0417932-3A patent/BRPI0417932A/pt not_active IP Right Cessation
- 2004-12-11 CA CA002551474A patent/CA2551474A1/en not_active Abandoned
- 2004-12-11 KR KR1020067012553A patent/KR20060121238A/ko not_active Withdrawn
- 2004-12-11 WO PCT/EP2004/014134 patent/WO2005063169A2/de not_active Ceased
- 2004-12-11 JP JP2006545984A patent/JP2007515439A/ja not_active Abandoned
- 2004-12-11 CN CNA2004800386251A patent/CN1897974A/zh active Pending
- 2004-12-11 MX MXPA06006645A patent/MXPA06006645A/es unknown
-
2006
- 2006-05-30 IL IL176026A patent/IL176026A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1699490A2 (de) | 2006-09-13 |
| DE10361067A1 (de) | 2005-07-14 |
| MXPA06006645A (es) | 2006-08-31 |
| WO2005063169A3 (de) | 2006-05-04 |
| WO2005063169A2 (de) | 2005-07-14 |
| CN1897974A (zh) | 2007-01-17 |
| CA2551474A1 (en) | 2005-07-14 |
| KR20060121238A (ko) | 2006-11-28 |
| AU2004308072A1 (en) | 2005-07-14 |
| IL176026A0 (en) | 2006-10-05 |
| JP2007515439A (ja) | 2007-06-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 9A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2260 DE 29/04/2014. |