BRPI0418223A - composição que compreende um extrato aquoso de folhas de vinha vermelha e um agente de melhoria da circulação sangüìnea para o tratamento de insuficiências venosas crÈnicas - Google Patents

composição que compreende um extrato aquoso de folhas de vinha vermelha e um agente de melhoria da circulação sangüìnea para o tratamento de insuficiências venosas crÈnicas

Info

Publication number
BRPI0418223A
BRPI0418223A BRPI0418223-5A BRPI0418223A BRPI0418223A BR PI0418223 A BRPI0418223 A BR PI0418223A BR PI0418223 A BRPI0418223 A BR PI0418223A BR PI0418223 A BRPI0418223 A BR PI0418223A
Authority
BR
Brazil
Prior art keywords
blood circulation
treatment
vine leaves
red vine
enhancing agent
Prior art date
Application number
BRPI0418223-5A
Other languages
English (en)
Inventor
Minoru Okada
Toshiaki Horie
Koichi Takahashi
Kenji Masuda
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of BRPI0418223A publication Critical patent/BRPI0418223A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415—Pyridoxine, i.e. Vitamin B6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A61K31/51—Thiamines, e.g. vitamin B1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Botany (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"COMPOSIçãO QUE COMPREENDE UM EXTRATO AQUOSO DE FOLHAS DE VINHA VERMELHA E UM AGENTE DE MELHORIA DA CIRCULAçãO SANGüìNEA PARA O TRATAMENTO DE INSUFICIêNCIAS VENOSAS CRÈNICAS". A presente invenção refere-se a uma nova composição que contém a dosagem eficaz de um extrato aquoso de folhas de vinha vermelha (1) e um agente de melhoria da circulação sangüínea (2) para prevenção ou alívio do desconforto associado à insuficiência venosa crónica branda a moderada das pernas. As composições de acordo com esta invenção poderão também conter aditivos farmacêutica ou dieteticamente aceitáveis.
BRPI0418223-5A 2003-12-29 2004-12-18 composição que compreende um extrato aquoso de folhas de vinha vermelha e um agente de melhoria da circulação sangüìnea para o tratamento de insuficiências venosas crÈnicas BRPI0418223A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03029894A EP1550450A1 (en) 2003-12-29 2003-12-29 Composition comprising an aqueous extract of red vine leaves and a blood circulating-improving agent for the treatment of chronic venous insufficiencies
PCT/EP2004/014456 WO2005063268A1 (en) 2003-12-29 2004-12-18 Composition comprising an aqueous extract of red vine leaves and a blood circulation-improving agent for the treatment of chronic venous insufficiences

Publications (1)

Publication Number Publication Date
BRPI0418223A true BRPI0418223A (pt) 2007-04-27

Family

ID=34560170

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0418223-5A BRPI0418223A (pt) 2003-12-29 2004-12-18 composição que compreende um extrato aquoso de folhas de vinha vermelha e um agente de melhoria da circulação sangüìnea para o tratamento de insuficiências venosas crÈnicas

Country Status (13)

Country Link
US (1) US20050202110A1 (pt)
EP (2) EP1550450A1 (pt)
JP (1) JP2007516991A (pt)
KR (1) KR20060130149A (pt)
CN (1) CN1901929A (pt)
AU (1) AU2004308616A1 (pt)
BR (1) BRPI0418223A (pt)
CA (1) CA2551580A1 (pt)
EC (1) ECSP066685A (pt)
MX (1) MXPA06007498A (pt)
RU (1) RU2006127300A (pt)
WO (1) WO2005063268A1 (pt)
ZA (1) ZA200604097B (pt)

Families Citing this family (12)

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JP2001122791A (ja) * 1999-10-20 2001-05-08 Boehringer Ingelheim Internatl Gmbh 下肢の慢性静脈不全の軽減および予防のための赤色ブドウ樹葉の水性抽出物よりなる食事補強剤
US20040151769A1 (en) * 2002-12-31 2004-08-05 Boehringer Ingelheim International Gmbh Film coated tablet containing an extract of red vine leaves
US20040151794A1 (en) * 2002-12-31 2004-08-05 Boehringer Ingelheim International Gmbh Method of improvement of blood circulation
UA90668C2 (ru) * 2004-02-19 2010-05-25 Бёрингер Ингельхайм Интернациональ Гмбх Состав для лечения хронической венозной недостаточности, который содержит водный экстракт листьев красного винограда и противовоспалительное средство
MX2010001693A (es) * 2007-08-31 2010-03-11 Boehringer Ingelheim Int Composicion pulverizable que contiene extracto de hojas de parra rojas.
DE102008012908A1 (de) * 2008-03-06 2009-09-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Methode zum anti-inflammatorischen und anti-ödematösen Schutz von explantiertem biologischen Material bis zu seiner Transplantation in Patienten
CN102246879B (zh) * 2011-06-24 2013-01-30 上海马陆葡萄公园有限公司 一种葡萄叶茶及其制备工艺
JP2015224205A (ja) * 2014-05-27 2015-12-14 エスエス製薬株式会社 冷え症等の全身症状改善用経口組成物
DE202014006415U1 (de) * 2014-08-12 2015-11-13 Boehringer Ingelheim International Gmbh Wasserlösliches Granulat zur Herstellung einer Trinklösung
CN106389700A (zh) * 2016-12-05 2017-02-15 广东伊茗药业有限公司 一种舒缓腿部肿胀的贴剂
FR3075602B1 (fr) * 2017-12-21 2020-06-12 Urgo Recherche Innovation Et Developpement Produit de combinaison pour la prevention et le traitement des insuffisances veineuses chroniques
KR20200115927A (ko) * 2019-03-29 2020-10-08 주식회사 유니베라 포도잎 추출물 및 병풀 추출물을 포함하는 정맥순환 장애 개선용 조성물

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US20040151769A1 (en) * 2002-12-31 2004-08-05 Boehringer Ingelheim International Gmbh Film coated tablet containing an extract of red vine leaves
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EP1550452A1 (en) * 2003-12-29 2005-07-06 Boehringer Ingelheim International GmbH Composition comprising an aqueous extract of red vine leaves and a antthrombotic agent for the treatment of chronic venous insufficiencies
EP1550451A1 (en) * 2003-12-29 2005-07-06 Boehringer Ingelheim International GmbH Composition comprising an aqueous extract of red vine leaves and a diuretic for the treatment of chronic venous insufficiencies
UA90668C2 (ru) * 2004-02-19 2010-05-25 Бёрингер Ингельхайм Интернациональ Гмбх Состав для лечения хронической венозной недостаточности, который содержит водный экстракт листьев красного винограда и противовоспалительное средство

Also Published As

Publication number Publication date
AU2004308616A1 (en) 2005-07-14
EP1550450A1 (en) 2005-07-06
MXPA06007498A (es) 2006-08-31
ZA200604097B (en) 2007-10-31
ECSP066685A (es) 2006-10-25
US20050202110A1 (en) 2005-09-15
CN1901929A (zh) 2007-01-24
WO2005063268A1 (en) 2005-07-14
KR20060130149A (ko) 2006-12-18
EP1708727A1 (en) 2006-10-11
RU2006127300A (ru) 2008-02-10
CA2551580A1 (en) 2005-07-14
JP2007516991A (ja) 2007-06-28

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