BRPI0418572A - composição farmacêutica revestida e sólida para uso veterinário e administração oral dos princìpios ativos de paladar desagradável e revestimento - Google Patents

composição farmacêutica revestida e sólida para uso veterinário e administração oral dos princìpios ativos de paladar desagradável e revestimento

Info

Publication number
BRPI0418572A
BRPI0418572A BRPI0418572-2A BRPI0418572A BRPI0418572A BR PI0418572 A BRPI0418572 A BR PI0418572A BR PI0418572 A BRPI0418572 A BR PI0418572A BR PI0418572 A BRPI0418572 A BR PI0418572A
Authority
BR
Brazil
Prior art keywords
coating
pharmaceutical composition
oral administration
solid
sweetener
Prior art date
Application number
BRPI0418572-2A
Other languages
English (en)
Inventor
Mario Oda Kokuta
Original Assignee
Laboratiorios K Nig S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratiorios K Nig S A filed Critical Laboratiorios K Nig S A
Publication of BRPI0418572A publication Critical patent/BRPI0418572A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

COMPOSIçãO FARMACêUTICA REVESTIDA E SóLIDA PARA USO VEERINáRIO E ADMINISTRAçãO ORAL DOS PRINCìPIOS ATIVOS DE PALADAR DESAGRADáVEL E REVESTIMENTO. A presente invenção se relaciona a uma composiçãofarmacêutica sólida de uso veterinário para a administração oral dos princípios ativos de sabor desagradável e revestimento, onde tal composição inclui um núcleo comprimido que tem pelo menos um pricípio ativo e excipientes farmaceuticamente aceitáveis, bem como um revestimento que inclui pelomenos um edulcorante e pelo menos uma compressão coadjuvante. O revestimento tem uma espessura de 2 a 4 mm que cobre completamente o núcleo ativo. O revestimento de edulcorante pode ser, por exemplo, lêvedo de cerveja, glutamato monosódico , hidrocloreto de L-lisina, pó de proteina hidrolisada, pó de essência de fígado, essência pó de essência de carne, pó de essência de coração ou suas combinações, onde tal edulcorante está presente em uma quantidade entre 3 e 60% p/p comparado ao peso total do revestimento. A compressão coadjuvante pode ser, por exemplo, polivinil-pirrolidona, estearato de magnésio, amido de milho ou lactose monohidratada, onde tal coadjuvante está presente em uma quantidade entre 3 e 45% p/p comparada ao peso total do revestimento.
BRPI0418572-2A 2004-02-27 2004-02-27 composição farmacêutica revestida e sólida para uso veterinário e administração oral dos princìpios ativos de paladar desagradável e revestimento BRPI0418572A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/BR2004/000023 WO2005081612A2 (en) 2004-02-27 2004-02-27 Solid and coated pharmaceutical composition, for veterinary use and for oral administration of active principles of disagreeable taste, and coat

Publications (1)

Publication Number Publication Date
BRPI0418572A true BRPI0418572A (pt) 2007-07-31

Family

ID=34891807

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0418572-2A BRPI0418572A (pt) 2004-02-27 2004-02-27 composição farmacêutica revestida e sólida para uso veterinário e administração oral dos princìpios ativos de paladar desagradável e revestimento

Country Status (3)

Country Link
AR (1) AR047705A1 (pt)
BR (1) BRPI0418572A (pt)
WO (1) WO2005081612A2 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009023013A1 (en) * 2007-08-13 2009-02-19 Alpharma, Inc. Praziquantel and cmetidine compositions and methods
HU231017B1 (hu) 2012-05-08 2019-11-28 LAVET Gyógyszeripari Kft. Praziquantel tartalmú ízfedett formulációk
CN107468711B (zh) * 2017-08-21 2020-02-11 河南省奥林特药业有限公司 一种从猪肝中提取精制肝精膏的制备方法
EP4208157A1 (en) 2020-09-04 2023-07-12 Elanco Us Inc. Palatable formulations

Also Published As

Publication number Publication date
WO2005081612A2 (en) 2005-09-09
AR047705A1 (es) 2006-02-08

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA:INT.CI.A61K 31/495, A61K 31/4985, A61K 31/517, A61K 47/42, A61K 47/46, A61K 9/28, A61P 25/22,A61P 33/00

Ipc: A61K 31/495 (2011.01), A61K 31/4985 (2011.01), A61

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2260 DE 29/04/2014.