BRPI0418804A - adesivo médico e métodos de adesão de tecido - Google Patents

adesivo médico e métodos de adesão de tecido

Info

Publication number
BRPI0418804A
BRPI0418804A BRPI0418804-7A BRPI0418804A BRPI0418804A BR PI0418804 A BRPI0418804 A BR PI0418804A BR PI0418804 A BRPI0418804 A BR PI0418804A BR PI0418804 A BRPI0418804 A BR PI0418804A
Authority
BR
Brazil
Prior art keywords
molecules
functional
mixture
biocompatible
crosslinked polymer
Prior art date
Application number
BRPI0418804-7A
Other languages
English (en)
Inventor
Eric J Beckman
Michael Buckley
Sudha Agarwal
Jianying Zhang
Original Assignee
Univ Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pittsburgh filed Critical Univ Pittsburgh
Publication of BRPI0418804A publication Critical patent/BRPI0418804A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0026—Sprayable compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0042—Materials resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/043—Mixtures of macromolecular materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Polyethers (AREA)

Abstract

ADESIVO MéDICO E MéTODOS DE ADESãO DE TECIDO. A presente invenção refere-se a um adesivo incluindo uma mistura de moléculas com terminação isocianato formadas pela reação de moléculas funcionais multiisocianato com moléculas precursoras multifuncionais incluindo grupos funcionais terminais selecionados do grupo que consiste de um grupo hidroxila, um grupo amino primário e um grupo amino secundário. Preferencialmente, os grupos funcionais são grupos hidroxila. Os compostos precursores multifuncionais são biocompatíveis. Precursores funcionais multiamina de moléculas funcionais multiisocianato também são biocompatíveis. Conforme discutido acima, a mistura de moléculas tem, preferencialmente, uma funcionalidade isocianato média de, no mínimo, 2,1 e, mais preferencialmente, tem uma funcionalidade isocianato média de, no mínimo, 2,5. Conforme também descrito acima, a mistura de moléculas tem, preferencialmente, uma viscosidade na faixa de aproximadamente 1 a aproximadamente 100 centipoise. A mistura de moléculas forma uma rede polimérica com ligações cruzadas quando em contato com o tecido orgânico na presença de água. A rede polimérica com ligações cruzadas é biocompatível e biodegradável. A rede polimérica com ligações cruzadas degrada em produtos de degradação incluindo as moléculas precursoras e os precursores funcionais multiamina.
BRPI0418804-7A 2004-05-27 2004-05-27 adesivo médico e métodos de adesão de tecido BRPI0418804A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2004/016767 WO2005118011A1 (en) 2004-05-27 2004-05-27 Medical adhesive and methods of tissue adhesion

Publications (1)

Publication Number Publication Date
BRPI0418804A true BRPI0418804A (pt) 2007-10-16

Family

ID=34958183

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0418804-7A BRPI0418804A (pt) 2004-05-27 2004-05-27 adesivo médico e métodos de adesão de tecido

Country Status (12)

Country Link
EP (1) EP1755693A1 (pt)
JP (1) JP2008500095A (pt)
CN (1) CN1968718B (pt)
AU (1) AU2004320265B2 (pt)
BR (1) BRPI0418804A (pt)
CA (1) CA2576223C (pt)
IL (1) IL179643A0 (pt)
MX (1) MXPA06013721A (pt)
NZ (1) NZ550970A (pt)
RU (1) RU2346704C2 (pt)
WO (1) WO2005118011A1 (pt)
ZA (1) ZA200609694B (pt)

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US8287566B2 (en) 2007-10-26 2012-10-16 Cohera Medical, Inc. Spray devices and methods
GB0722820D0 (en) 2007-11-21 2008-01-02 Smith & Nephew Vacuum assisted wound dressing
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WO2012068052A2 (en) * 2010-11-15 2012-05-24 Cohera Medical, Inc. Biodegradable compositions having pressure sensitive adhesive properties
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US20160120706A1 (en) 2013-03-15 2016-05-05 Smith & Nephew Plc Wound dressing sealant and use thereof
EP2968647B1 (en) 2013-03-15 2022-06-29 Smith & Nephew plc Wound dressing sealant and use thereof
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CN106267324A (zh) * 2016-08-09 2017-01-04 西北师范大学 一种温度响应型高分子生物医用胶黏剂及其合成方法
EP3615586B1 (en) * 2017-04-28 2021-02-17 Evonik Operations GmbH Biodegradable bone glue
CN112807480B (zh) * 2018-08-20 2022-08-09 稳得希林(杭州)生物科技有限公司 多糖基组织粘合医用胶及其应用
KR102190917B1 (ko) * 2018-08-31 2020-12-15 씨제이제일제당 주식회사 점착 조성물, 및 이의 제조방법
CN113150239A (zh) * 2021-04-09 2021-07-23 华南理工大学 一种固化时长可控的医用聚氨酯粘合剂的制备方法
CN113925996A (zh) * 2021-09-22 2022-01-14 华南理工大学 一种用于骨缺损修复的医用粘合剂及其使用方法
CN113769153A (zh) * 2021-09-22 2021-12-10 华南理工大学 一种用于肠道创伤修复的医用粘合剂及其使用方法
CN114250057B (zh) * 2021-12-27 2022-09-02 四川大学 一种含邻苯二酚基团的聚氨酯粘合剂及其制备方法和应用
CN114832146A (zh) * 2022-04-06 2022-08-02 华南理工大学 一种用于骨组织创伤修复的医用粘合剂及其使用方法
CN114907540A (zh) * 2022-05-17 2022-08-16 浙江欧鹿医疗器械有限公司 聚氨酯类高分子聚合物及其制备方法，聚氨酯类高分子聚合物水凝胶、试剂盒及其应用
CN116392627B (zh) * 2023-03-21 2024-09-27 北京大清生物技术股份有限公司 一种用于软组织修复的医用粘合剂、制品及其制备方法

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Also Published As

Publication number Publication date
MXPA06013721A (es) 2007-04-17
CN1968718A (zh) 2007-05-23
CA2576223C (en) 2013-10-08
CN1968718B (zh) 2010-06-09
WO2005118011A1 (en) 2005-12-15
AU2004320265A2 (en) 2005-12-15
AU2004320265A1 (en) 2005-12-15
NZ550970A (en) 2010-01-29
ZA200609694B (en) 2008-04-30
RU2006144819A (ru) 2008-07-10
RU2346704C2 (ru) 2009-02-20
IL179643A0 (en) 2007-05-15
JP2008500095A (ja) 2008-01-10
EP1755693A1 (en) 2007-02-28
CA2576223A1 (en) 2005-12-15
AU2004320265B2 (en) 2011-03-03

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]