BRPI0418804A - adesivo médico e métodos de adesão de tecido - Google Patents

adesivo médico e métodos de adesão de tecido

Info

Publication number
BRPI0418804A
BRPI0418804A BRPI0418804-7A BRPI0418804A BRPI0418804A BR PI0418804 A BRPI0418804 A BR PI0418804A BR PI0418804 A BRPI0418804 A BR PI0418804A BR PI0418804 A BRPI0418804 A BR PI0418804A
Authority
BR
Brazil
Prior art keywords
molecules
functional
mixture
biocompatible
crosslinked polymer
Prior art date
Application number
BRPI0418804-7A
Other languages
English (en)
Inventor
Eric J Beckman
Michael Buckley
Sudha Agarwal
Jianying Zhang
Original Assignee
Univ Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pittsburgh filed Critical Univ Pittsburgh
Publication of BRPI0418804A publication Critical patent/BRPI0418804A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0026—Sprayable compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0042—Materials resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/043—Mixtures of macromolecular materials

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Materials For Medical Uses (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Polyethers (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Biological Depolymerization Polymers (AREA)

Abstract

ADESIVO MéDICO E MéTODOS DE ADESãO DE TECIDO. A presente invenção refere-se a um adesivo incluindo uma mistura de moléculas com terminação isocianato formadas pela reação de moléculas funcionais multiisocianato com moléculas precursoras multifuncionais incluindo grupos funcionais terminais selecionados do grupo que consiste de um grupo hidroxila, um grupo amino primário e um grupo amino secundário. Preferencialmente, os grupos funcionais são grupos hidroxila. Os compostos precursores multifuncionais são biocompatíveis. Precursores funcionais multiamina de moléculas funcionais multiisocianato também são biocompatíveis. Conforme discutido acima, a mistura de moléculas tem, preferencialmente, uma funcionalidade isocianato média de, no mínimo, 2,1 e, mais preferencialmente, tem uma funcionalidade isocianato média de, no mínimo, 2,5. Conforme também descrito acima, a mistura de moléculas tem, preferencialmente, uma viscosidade na faixa de aproximadamente 1 a aproximadamente 100 centipoise. A mistura de moléculas forma uma rede polimérica com ligações cruzadas quando em contato com o tecido orgânico na presença de água. A rede polimérica com ligações cruzadas é biocompatível e biodegradável. A rede polimérica com ligações cruzadas degrada em produtos de degradação incluindo as moléculas precursoras e os precursores funcionais multiamina.
BRPI0418804-7A 2004-05-27 2004-05-27 adesivo médico e métodos de adesão de tecido BRPI0418804A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2004/016767 WO2005118011A1 (en) 2004-05-27 2004-05-27 Medical adhesive and methods of tissue adhesion

Publications (1)

Publication Number Publication Date
BRPI0418804A true BRPI0418804A (pt) 2007-10-16

Family

ID=34958183

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0418804-7A BRPI0418804A (pt) 2004-05-27 2004-05-27 adesivo médico e métodos de adesão de tecido

Country Status (12)

Country Link
EP (1) EP1755693A1 (pt)
JP (1) JP2008500095A (pt)
CN (1) CN1968718B (pt)
AU (1) AU2004320265B2 (pt)
BR (1) BRPI0418804A (pt)
CA (1) CA2576223C (pt)
IL (1) IL179643A0 (pt)
MX (1) MXPA06013721A (pt)
NZ (1) NZ550970A (pt)
RU (1) RU2346704C2 (pt)
WO (1) WO2005118011A1 (pt)
ZA (1) ZA200609694B (pt)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7264823B2 (en) 2002-02-08 2007-09-04 University Of Pittsburgh Medical adhesive and methods of tissue adhesion
CA2613540A1 (en) * 2005-07-01 2007-01-11 University Of Pittsburgh Wound healing polymeric networks
AU2007210055A1 (en) * 2006-01-27 2007-08-09 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Medical adhesive and methods of tissue adhesion
US7597882B2 (en) * 2006-04-24 2009-10-06 Incept Llc Protein crosslinkers, crosslinking methods and applications thereof
DE102007038125A1 (de) 2007-08-03 2009-02-05 Aesculap Ag Kombination zum Verkleben von biologischen Geweben
US8287566B2 (en) 2007-10-26 2012-10-16 Cohera Medical, Inc. Spray devices and methods
HUE049431T2 (hu) 2007-11-21 2020-09-28 Smith & Nephew Sebkötözés
US8808259B2 (en) 2007-11-21 2014-08-19 T.J. Smith & Nephew Limited Suction device and dressing
GB0722820D0 (en) 2007-11-21 2008-01-02 Smith & Nephew Vacuum assisted wound dressing
US11253399B2 (en) 2007-12-06 2022-02-22 Smith & Nephew Plc Wound filling apparatuses and methods
GB0723875D0 (en) 2007-12-06 2008-01-16 Smith & Nephew Wound management
US20130096518A1 (en) 2007-12-06 2013-04-18 Smith & Nephew Plc Wound filling apparatuses and methods
US20090192554A1 (en) * 2008-01-29 2009-07-30 Confluent Surgical, Inc. Bioabsorbable block copolymer
GB0803564D0 (en) 2008-02-27 2008-04-02 Smith & Nephew Fluid collection
GB0902816D0 (en) 2009-02-19 2009-04-08 Smith & Nephew Fluid communication path
WO2010111570A1 (en) * 2009-03-27 2010-09-30 E. I. Du Pont De Nemours And Company Polyglycerol aldehydes
ITMI20100440A1 (it) * 2010-03-18 2011-09-19 Dow Global Technologies Inc Processo per la preparazione di poliuretani rinforzati con fibre lunghe che contengono riempitivi particolati
US9061095B2 (en) 2010-04-27 2015-06-23 Smith & Nephew Plc Wound dressing and method of use
GB201011173D0 (en) 2010-07-02 2010-08-18 Smith & Nephew Provision of wound filler
NZ611998A (en) * 2010-11-15 2014-11-28 Cohera Medical Inc Biodegradable compositions having pressure sensitive adhesive properties
MX337627B (es) 2010-11-25 2016-03-10 Smith & Nephew Composiciones i-ii y productos y usos de la misma.
GB201020005D0 (en) 2010-11-25 2011-01-12 Smith & Nephew Composition 1-1
US20150159066A1 (en) 2011-11-25 2015-06-11 Smith & Nephew Plc Composition, apparatus, kit and method and uses thereof
US20160120706A1 (en) 2013-03-15 2016-05-05 Smith & Nephew Plc Wound dressing sealant and use thereof
EP2968647B1 (en) 2013-03-15 2022-06-29 Smith & Nephew plc Wound dressing sealant and use thereof
US9839222B2 (en) 2014-08-28 2017-12-12 Universidad Eafit Process for increasing biomass and spores production of plant growth promoting bacteria of the bacillus genus
RU2597902C1 (ru) * 2015-05-06 2016-09-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Чувашский государственный университет имени И.Н. Ульянова" Клей полимерный
CN106267324A (zh) * 2016-08-09 2017-01-04 西北师范大学 一种温度响应型高分子生物医用胶黏剂及其合成方法
EP3615586B1 (en) * 2017-04-28 2021-02-17 Evonik Operations GmbH Biodegradable bone glue
CN112807480B (zh) * 2018-08-20 2022-08-09 稳得希林(杭州)生物科技有限公司 多糖基组织粘合医用胶及其应用
KR102190917B1 (ko) 2018-08-31 2020-12-15 씨제이제일제당 주식회사 점착 조성물, 및 이의 제조방법
CN113150239A (zh) * 2021-04-09 2021-07-23 华南理工大学 一种固化时长可控的医用聚氨酯粘合剂的制备方法
CN113925996A (zh) * 2021-09-22 2022-01-14 华南理工大学 一种用于骨缺损修复的医用粘合剂及其使用方法
CN113769153A (zh) * 2021-09-22 2021-12-10 华南理工大学 一种用于肠道创伤修复的医用粘合剂及其使用方法
CN114250057B (zh) * 2021-12-27 2022-09-02 四川大学 一种含邻苯二酚基团的聚氨酯粘合剂及其制备方法和应用
CN114832146A (zh) * 2022-04-06 2022-08-02 华南理工大学 一种用于骨组织创伤修复的医用粘合剂及其使用方法
CN114907540A (zh) * 2022-05-17 2022-08-16 浙江欧鹿医疗器械有限公司 聚氨酯类高分子聚合物及其制备方法，聚氨酯类高分子聚合物水凝胶、试剂盒及其应用
CN116392627B (zh) * 2023-03-21 2024-09-27 北京大清生物技术股份有限公司 一种用于软组织修复的医用粘合剂、制品及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62148666A (ja) * 1985-08-30 1987-07-02 三洋化成工業株式会社 外科用接着剤
US4740534A (en) * 1985-08-30 1988-04-26 Sanyo Chemical Industries, Ltd. Surgical adhesive
JPS63278924A (ja) * 1987-05-09 1988-11-16 Bio Material Yunibaasu:Kk 生体内分解吸収性ウレタンプレポリマ−
US4804691A (en) * 1987-08-28 1989-02-14 Richards Medical Company Method for making a biodegradable adhesive for soft living tissue
JPH02249555A (ja) * 1989-03-23 1990-10-05 Sanyo Chem Ind Ltd 気管・肺手術用シーリング剤および方法
IL94910A (en) * 1990-06-29 1994-04-12 Technion Research Dev Foundati Biomedical adhesive compositions
US6136136A (en) * 1992-11-25 2000-10-24 Henkel Corporation Moisture-curable polyurethane hotmelt adhesives with high green strength
US6339130B1 (en) * 1994-07-22 2002-01-15 United States Surgical Corporation Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom
CN1453326A (zh) * 2002-04-28 2003-11-05 王喆 多功能水性高分子聚合物粘合剂
EP1556430B1 (en) * 2002-10-28 2009-06-24 Tyco Healthcare Group Lp Bioabsorbable adhesive compounds

Also Published As

Publication number Publication date
RU2006144819A (ru) 2008-07-10
NZ550970A (en) 2010-01-29
AU2004320265B2 (en) 2011-03-03
CN1968718B (zh) 2010-06-09
AU2004320265A2 (en) 2005-12-15
RU2346704C2 (ru) 2009-02-20
EP1755693A1 (en) 2007-02-28
CN1968718A (zh) 2007-05-23
CA2576223A1 (en) 2005-12-15
WO2005118011A1 (en) 2005-12-15
AU2004320265A1 (en) 2005-12-15
MXPA06013721A (es) 2007-04-17
ZA200609694B (en) 2008-04-30
CA2576223C (en) 2013-10-08
IL179643A0 (en) 2007-05-15
JP2008500095A (ja) 2008-01-10

Similar Documents

Publication Publication Date Title
WO2006060182A3 (en) HIGHLY BRANCHED HK PEPTIDES AS EFFECTIVE CARRIERS OF siRNA
BRPI0416032A (pt) excipientes em veìculos de distribuição de fármacos
SG165315A1 (en) Alpha2c adrenoreceptor agonists
BR0318278A (pt) compostos de éter aminocicloexìlico e usos dos mesmo
BRPI0615307A2 (pt) agonistas de adrenorreceptor alfa2c
BRPI0514444A (pt) análogos de ciclopamina e métodos de uso destes
BR112012011534A2 (pt) materiais de liberação de blenda de fluorossilicone
MX2007002398A (es) Nuevas composiciones farmaceuticas para el tratamiento de cancer.
BRPI0511663A (pt) composição compreendendo água e um componente de sólidos, processo, e, tablete revestido
BR9609534B1 (pt) processo para preparar uma composição de gel de polissacarìdeo biocompatìvel reticulada, e, composição de gel de polissacarìdeo.
WO2010064806A3 (ko) 유착방지용 조성물
WO2008076243A3 (en) Acyl bipiperidinyl compounds, compositions containing such compounds and methods of treatment
WO2003097608A3 (en) Opioid and opioid-like compounds and uses thereof
RU2008124150A (ru) Гелевая композиция и ее применение
WO2004028272A3 (en) Injectable growth promoting and anthelmintic composition
BR0014417A (pt) Processo para preparação de uma mistura polimérica dispersada em água, mistura polimérica dispersada em água, composição para preparação de um revestimento resistente à água, e, artigo revestido resistente à água
BR112012030344A2 (pt) metilestireno contendo grupo hidroxila e polímeros incorporando o mesmo
TW200613338A (en) Moisture-curable, silane crosslinking compositions
BRPI0809981A2 (pt) Compostos, processo de fabricação destes, composição farmacêutica que os contém, método de tratamento e/ou prevenção de doenças que são associadas a modulação de receptores de sst subtipo 5 e uso dos compostos.
EP1630202A3 (en) One-part organopolysiloxane gel compositions, their preparation and use
ATE228828T1 (de) Verfahren zur herstellung von festen cyclodextrinhaltigen dosierungsformen
MX339671B (es) Forma oral solida con perfil de liberacion dual que contiene particulas multiples.
EP1454620A3 (en) Skin aging-preventing or improving agent
WO2010039791A8 (en) Cellular elastomer compositions
WO2009078978A3 (en) Compositions containing polyglycidol-based polymers and uses thereof

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]