BRPI0500520A - uso de agentes flavorizantes aromáticos de alto ponto de fusão como agentes solubilizantes ou inibidores de cristalização em composições farmacêuticas - Google Patents
uso de agentes flavorizantes aromáticos de alto ponto de fusão como agentes solubilizantes ou inibidores de cristalização em composições farmacêuticasInfo
- Publication number
- BRPI0500520A BRPI0500520A BRPI0500520-5A BRPI0500520A BRPI0500520A BR PI0500520 A BRPI0500520 A BR PI0500520A BR PI0500520 A BRPI0500520 A BR PI0500520A BR PI0500520 A BRPI0500520 A BR PI0500520A
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical compositions
- agents
- crystallization inhibitors
- solubilizing agents
- high melting
- Prior art date
Links
- 239000000796 flavoring agent Substances 0.000 title abstract 4
- 239000003112 inhibitor Substances 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 4
- 239000002904 solvent Substances 0.000 title abstract 4
- 125000003118 aryl group Chemical group 0.000 title abstract 3
- 238000002425 crystallisation Methods 0.000 title abstract 3
- 230000008025 crystallization Effects 0.000 title abstract 3
- 238000002844 melting Methods 0.000 title abstract 3
- 230000008018 melting Effects 0.000 title abstract 3
- 235000013355 food flavoring agent Nutrition 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 235000019634 flavors Nutrition 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"USO DE AGENTES FLAVORIZANTES AROMáTICOS DE ALTO PONTO DE FUSãO COMO AGENTES SOLUBILIZANTES OU INIBIDORES DE CRISTALIZAçãO EM COMPOSIçõES FARMACêUTICAS". A presente invenção consiste de processos de manufatura de composições farmacêuticas caracterizadas pelo uso de compostos flavorizantes aromáticos com ponto de fusão superior a 20<198>C como agentes solubilizantes ou inibidores da cristalização. Complementarmente, a presente invenção também compreende composições farmacêuticas caracterizadas por conterem compostos flavorizantes aromáticos com ponto de fusão superior a 20 <198>C como agentes solubilizantes ou inibidores da cristalização.
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI0500520-5A BRPI0500520A (pt) | 2005-02-16 | 2005-02-16 | uso de agentes flavorizantes aromáticos de alto ponto de fusão como agentes solubilizantes ou inibidores de cristalização em composições farmacêuticas |
| ARP060100561A AR053681A1 (es) | 2005-02-16 | 2006-02-16 | Uso de agentes saborizantes aromaticos de alto punto de fusion como agentes solubilicantes o inhibidores de la cristalizacion en composiciones farmaceuticas |
| PCT/BR2006/000024 WO2006086862A1 (en) | 2005-02-16 | 2006-02-16 | Use of aromatic flavouring agents with high melting point as solubilizing agents |
| EP06705070A EP1853319A4 (en) | 2005-02-16 | 2006-02-16 | USE OF HIGH MELT AROMATIC FLAVORS AS SOLUBILIZING AGENTS |
| US11/889,764 US20080064675A1 (en) | 2005-02-16 | 2007-08-16 | Use of Aromatic flavoring agents with high melting point as solubilizing agents |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI0500520-5A BRPI0500520A (pt) | 2005-02-16 | 2005-02-16 | uso de agentes flavorizantes aromáticos de alto ponto de fusão como agentes solubilizantes ou inibidores de cristalização em composições farmacêuticas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0500520A true BRPI0500520A (pt) | 2006-09-26 |
Family
ID=36916127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0500520-5A BRPI0500520A (pt) | 2005-02-16 | 2005-02-16 | uso de agentes flavorizantes aromáticos de alto ponto de fusão como agentes solubilizantes ou inibidores de cristalização em composições farmacêuticas |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20080064675A1 (pt) |
| EP (1) | EP1853319A4 (pt) |
| AR (1) | AR053681A1 (pt) |
| BR (1) | BRPI0500520A (pt) |
| WO (1) | WO2006086862A1 (pt) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1132518A (en) * | 1965-02-18 | 1968-11-06 | Richardson Merrell Inc | Medicinal composition |
| DE3339236A1 (de) * | 1983-10-28 | 1985-05-09 | Bayer Ag | Arzneimittelzubereitung |
| US5665386A (en) * | 1995-06-07 | 1997-09-09 | Avmax, Inc. | Use of essential oils to increase bioavailability of oral pharmaceutical compounds |
| DE60020382T2 (de) * | 1999-09-21 | 2006-01-26 | Skyepharma Canada Inc., Verdun | Oberflächenmodifizierte teilchenförmige zusammensetzungen biologisch aktiver stoffe |
| KR101098749B1 (ko) * | 2000-07-27 | 2011-12-23 | 테바 파마슈티컬 인더스트리즈 리미티드 | 결정질의 순수한 모다피닐 및 이의 제조 방법 |
| US6489363B2 (en) * | 2000-10-11 | 2002-12-03 | Cephalon, Inc. | Pharmaceutical solutions of modafinil compounds |
| AU2003211007A1 (en) * | 2002-02-18 | 2003-09-09 | Michigan State University | Method of treating inflammation and inflammation-related pain |
| US20040116532A1 (en) * | 2002-09-13 | 2004-06-17 | Craig Heacock | Pharmaceutical formulations of modafinil |
| BRPI0501120A (pt) * | 2005-02-18 | 2006-10-03 | Henry Jun Suzuki | composições farmacêuticas orais e parenterais contendo altas concentrações de agentes solubilizantes aromáticos |
-
2005
- 2005-02-16 BR BRPI0500520-5A patent/BRPI0500520A/pt not_active IP Right Cessation
-
2006
- 2006-02-16 EP EP06705070A patent/EP1853319A4/en not_active Withdrawn
- 2006-02-16 WO PCT/BR2006/000024 patent/WO2006086862A1/en not_active Ceased
- 2006-02-16 AR ARP060100561A patent/AR053681A1/es not_active Application Discontinuation
-
2007
- 2007-08-16 US US11/889,764 patent/US20080064675A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1853319A4 (en) | 2012-01-18 |
| AR053681A1 (es) | 2007-05-16 |
| WO2006086862A1 (en) | 2006-08-24 |
| EP1853319A1 (en) | 2007-11-14 |
| US20080064675A1 (en) | 2008-03-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUIDADE(S). |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2204 DE 02/04/2013. |