BRPI0507664A - compostos com atividade antitumor - Google Patents

compostos com atividade antitumor

Info

Publication number
BRPI0507664A
BRPI0507664A BRPI0507664-1A BRPI0507664A BRPI0507664A BR PI0507664 A BRPI0507664 A BR PI0507664A BR PI0507664 A BRPI0507664 A BR PI0507664A BR PI0507664 A BRPI0507664 A BR PI0507664A
Authority
BR
Brazil
Prior art keywords
compounds
antitumor activity
antitumor
optionally
formula
Prior art date
Application number
BRPI0507664-1A
Other languages
English (en)
Inventor
Gianfranco Peluso
Menotti Calvani
Original Assignee
Defiante Farmaceutica Lda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Defiante Farmaceutica Lda filed Critical Defiante Farmaceutica Lda
Publication of BRPI0507664A publication Critical patent/BRPI0507664A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

COMPOSTOS COM ATIVIDADE ANTITUMOR. A presente invenção refere-se ao uso de compostos de fórmula (I), onde X, Y e Z são definidos como na descrição da invenção, para a preparação de um medicamento antitumor, opcionalmente em combinação com diferentes substâncias biologicamente ativas.
BRPI0507664-1A 2004-02-12 2005-02-08 compostos com atividade antitumor BRPI0507664A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000230A ITMI20040230A1 (it) 2004-02-12 2004-02-12 Composti ad attivita' antitumorale
PCT/EP2005/001257 WO2005077354A1 (en) 2004-02-12 2005-02-08 Compounds having antitumor activity

Publications (1)

Publication Number Publication Date
BRPI0507664A true BRPI0507664A (pt) 2007-07-17

Family

ID=34856910

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0507664-1A BRPI0507664A (pt) 2004-02-12 2005-02-08 compostos com atividade antitumor

Country Status (19)

Country Link
US (1) US7652066B2 (pt)
EP (1) EP1713461B1 (pt)
JP (1) JP2007522165A (pt)
KR (1) KR101220331B1 (pt)
CN (1) CN1917867B (pt)
AR (1) AR047742A1 (pt)
AT (1) ATE476973T1 (pt)
AU (1) AU2005211906B2 (pt)
BR (1) BRPI0507664A (pt)
CA (1) CA2556069C (pt)
CY (1) CY1111048T1 (pt)
DE (1) DE602005022828D1 (pt)
DK (1) DK1713461T3 (pt)
ES (1) ES2350695T3 (pt)
IT (1) ITMI20040230A1 (pt)
PL (1) PL1713461T3 (pt)
SI (1) SI1713461T1 (pt)
TW (1) TWI361802B (pt)
WO (1) WO2005077354A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8314144B2 (en) * 2004-02-12 2012-11-20 Defiante Farmaceutica, S.A. Compounds having antitumor activity
WO2008109991A1 (en) 2007-03-09 2008-09-18 University Health Network Inhibitors of carnitine palmitoyltransferase and treating cancer
CA2694724C (en) 2007-08-01 2017-09-12 University Health Network Cyclic inhibitors of carnitine palmitoyltransferase and treating cancer
JP5474047B2 (ja) * 2008-04-29 2014-04-16 エフ．ホフマン−ラ ロシュ アーゲー ４−ジメチルアミノ酪酸誘導体
JP2011525530A (ja) * 2008-06-24 2011-09-22 ダラ・バイオサイエンシズ，インコーポレイテッド 酵素阻害剤およびその使用
JP5746988B2 (ja) * 2012-02-15 2015-07-08 ライオン株式会社 カプセル皮膜及びカプセル

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1299266B1 (it) 1998-05-15 2000-02-29 Sigma Tau Ind Farmaceuti Inibitori reversibili della carnitina palmitoil trasferasi
KR20090031957A (ko) * 1999-11-12 2009-03-30 더 존스 홉킨스 유니버시티 세포내 말로닐 ＣｏＡ의 수준을 증가시킴에 의한 암의 치료방법

Also Published As

Publication number Publication date
SI1713461T1 (sl) 2010-12-31
US7652066B2 (en) 2010-01-26
KR101220331B1 (ko) 2013-01-09
JP2007522165A (ja) 2007-08-09
TWI361802B (en) 2012-04-11
CY1111048T1 (el) 2015-06-11
AU2005211906B2 (en) 2009-07-30
EP1713461A1 (en) 2006-10-25
PL1713461T3 (pl) 2011-01-31
ES2350695T3 (es) 2011-01-26
AU2005211906A1 (en) 2005-08-25
TW200530154A (en) 2005-09-16
CN1917867B (zh) 2011-03-16
CA2556069C (en) 2013-04-23
DE602005022828D1 (de) 2010-09-23
HK1099687A1 (en) 2007-08-24
AR047742A1 (es) 2006-02-15
US20080227683A1 (en) 2008-09-18
EP1713461B1 (en) 2010-08-11
ATE476973T1 (de) 2010-08-15
KR20060134059A (ko) 2006-12-27
CA2556069A1 (en) 2005-08-25
ITMI20040230A1 (it) 2004-05-12
WO2005077354A1 (en) 2005-08-25
CN1917867A (zh) 2007-02-21
DK1713461T3 (da) 2010-11-22

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: DEFIANTE FARMACEUTICA, S.A. (PT)

Free format text: ALTERADO DE: DEFIANTE FARMACEUTICA LDA

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 10A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2308 DE 31/03/2015.