BRPI0507987A - métodos e compostos moduladores receptor de glicocorticóide - Google Patents

métodos e compostos moduladores receptor de glicocorticóide

Info

Publication number
BRPI0507987A
BRPI0507987A BRPI0507987-0A BRPI0507987A BRPI0507987A BR PI0507987 A BRPI0507987 A BR PI0507987A BR PI0507987 A BRPI0507987 A BR PI0507987A BR PI0507987 A BRPI0507987 A BR PI0507987A
Authority
BR
Brazil
Prior art keywords
compounds
glucocorticoid receptor
receptor modulating
methods
modulating methods
Prior art date
Application number
BRPI0507987-0A
Other languages
English (en)
Inventor
Lin Zhi
Robert J Ardecky
Dean Phillips
John S Tyhonas
Donald S Karanewsky
Robert I Higuchi
Andrew Richard Hudson
Steven L Roach
Angie C Vassar
Yongkai Li
Mark E Adams
Lino Juan Valdez
Catalina Cuervo
Original Assignee
Ligand Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ligand Pharm Inc filed Critical Ligand Pharm Inc
Publication of BRPI0507987A publication Critical patent/BRPI0507987A/pt

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    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
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    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Gastroenterology & Hepatology (AREA)

Abstract

MéTODOS E COMPOSTOS MODULADORES DE RECEPTOR DE GLICOCORTICóIDE São fornecidos compostos da Fórmula I: e derivados farmaceuticametne aceitáveis dos mesmos. Certos desses compostos são moduladores de receptor de glicocorticóide seletivos e/ou agentes de ligação de glicocorticóide seletivos. São também fornecidos métodos de fabricar e utilizar tais compostos, incluindo, porém não limitado ao uso desses compostos para tratar várias condições.
BRPI0507987-0A 2004-02-25 2005-02-24 métodos e compostos moduladores receptor de glicocorticóide BRPI0507987A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54815404P 2004-02-25 2004-02-25
PCT/US2005/006627 WO2005082909A1 (en) 2004-02-25 2005-02-24 Glucocorticoid receptor modulator compounds and methods- utility

Publications (1)

Publication Number Publication Date
BRPI0507987A true BRPI0507987A (pt) 2007-07-31

Family

ID=34910991

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0507987-0A BRPI0507987A (pt) 2004-02-25 2005-02-24 métodos e compostos moduladores receptor de glicocorticóide

Country Status (8)

Country Link
US (1) US20090105292A9 (pt)
EP (1) EP1718653A1 (pt)
JP (1) JP2007523950A (pt)
CN (1) CN1950375A (pt)
AR (1) AR048072A1 (pt)
BR (1) BRPI0507987A (pt)
CA (1) CA2557278A1 (pt)
WO (1) WO2005082909A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7026484B2 (en) * 2001-02-23 2006-04-11 Ligand Pharmaceuticals Incorporated Tricyclic androgen receptor modulator compounds and methods
US8268820B2 (en) * 2009-03-26 2012-09-18 Hoffmann-La Roche Inc. 2,3-diaryl- or heteroaryl-substituted 1,1,1-trifluoro-2-hydroxypropyl compounds
WO2011087946A1 (en) * 2010-01-15 2011-07-21 Rigel Pharmaceuticals, Inc. Screening assay employing dex and gdf8
US9314473B2 (en) 2011-02-03 2016-04-19 Pop Test Oncology Limited Liability Company System and method for diagnosis and treatment
CN102584841B (zh) * 2011-12-16 2014-11-12 浙江工业大学 一种喹啉香豆素衍生物及其制备方法及用途
WO2017180086A1 (en) * 2016-04-11 2017-10-19 Pop Test Oncology Limited Liability Company System and method for diagnosis and treatment
CN106967077B (zh) * 2017-05-18 2019-02-19 江苏理工学院 一种色烯并[2,3-b]喹啉衍生物及其制备方法和应用
JP7516394B2 (ja) * 2019-01-22 2024-07-16 アクリベス ビオメディカル ゲーエムベーハー 皮膚創傷治癒不全を治療するための選択的グルココルチコイド受容体モジュレーター

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6506766B1 (en) * 1998-02-13 2003-01-14 Abbott Laboratories Glucocortiocoid-selective antinflammatory agents

Also Published As

Publication number Publication date
JP2007523950A (ja) 2007-08-23
CN1950375A (zh) 2007-04-18
WO2005082909A1 (en) 2005-09-09
EP1718653A1 (en) 2006-11-08
AR048072A1 (es) 2006-03-29
CA2557278A1 (en) 2005-09-09
US20070281959A1 (en) 2007-12-06
US20090105292A9 (en) 2009-04-23

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07B Technical examination (opinion): publication cancelled [chapter 7.2 patent gazette]