BRPI0509023A - nitrila hidratase de rhodococcus - Google Patents

nitrila hidratase de rhodococcus

Info

Publication number
BRPI0509023A
BRPI0509023A BRPI0509023-7A BRPI0509023A BRPI0509023A BR PI0509023 A BRPI0509023 A BR PI0509023A BR PI0509023 A BRPI0509023 A BR PI0509023A BR PI0509023 A BRPI0509023 A BR PI0509023A
Authority
BR
Brazil
Prior art keywords
rhodococcus
transformed microorganisms
hydratase
nitrile hydrate
hydrate
Prior art date
Application number
BRPI0509023-7A
Other languages
English (en)
Inventor
Steffen Osswald
Stefan Verseck
Uta Deiting
Christoph Weckbecker
Klaus Huthmacher
Michael Binder
Maria-Regina Kula
Konrad Odendahl
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Publication of BRPI0509023A publication Critical patent/BRPI0509023A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

NITRILA HIDRATASE DE RHODOCOCCUS. A invenção refere-se a um cluster de polinucleotídeo de Rhodococcus, que codifica o polipeptídeo com a atividade de uma nitrila hidratase, uma proteína auxiliar P15K ativadora de uma dessas enzimas e uma seqüência de nucleotídeos codificadora de transportador de cobalto, contém microorganismos transformados, nos quais seqüências de nucleotídeos codificadoras dessas proteínas se apresentam reforçadas, e o emprego dos microorganismos transformados para preparação de amidas a partir de nitrilas.
BRPI0509023-7A 2004-03-20 2005-03-01 nitrila hidratase de rhodococcus BRPI0509023A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200410013824 DE102004013824A1 (de) 2004-03-20 2004-03-20 Nitrilhydratasen aus Rhodococcus opacus
PCT/EP2005/002134 WO2005093080A2 (de) 2004-03-20 2005-03-01 Nitrilhydratase aus rhodococcus

Publications (1)

Publication Number Publication Date
BRPI0509023A true BRPI0509023A (pt) 2007-08-07

Family

ID=34961837

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0509023-7A BRPI0509023A (pt) 2004-03-20 2005-03-01 nitrila hidratase de rhodococcus

Country Status (9)

Country Link
US (2) US7288402B2 (pt)
EP (1) EP1730291B1 (pt)
JP (1) JP5080240B2 (pt)
CN (1) CN1930299B (pt)
BR (1) BRPI0509023A (pt)
DE (1) DE102004013824A1 (pt)
ES (1) ES2400360T3 (pt)
RU (1) RU2385932C2 (pt)
WO (1) WO2005093080A2 (pt)

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DE10301007A1 (de) 2003-01-13 2004-07-22 Röhm GmbH & Co. KG Verbessertes Verfahren zur kontinuierlichen Herstellung von Alkyl(meth)acrylaten mit mehrfacher Katalysatorrezyklierung.
DE102005023976A1 (de) * 2005-05-20 2006-11-23 Röhm Gmbh Verfahren zur Umesterung
DE102005023975A1 (de) * 2005-05-20 2006-11-23 Röhm Gmbh Verfahren zur Herstellung von Alkyl(meth)acrylaten
DE102005043719A1 (de) * 2005-09-13 2007-03-15 Röhm Gmbh Vorrichtung und Verfahren für kontinuierlich durchgeführte Gleichgewichtsreaktionen
DE102006010254B4 (de) * 2006-03-02 2008-09-04 Evonik Degussa Gmbh Enzymkatalysierte Hydrolyse von optisch aktivem 2-Hydroxy-4-(methylthio)buttersäurenitril
EP1842907A1 (en) 2006-04-07 2007-10-10 B.R.A.I.N. Ag A group of novel enantioselective microbial nitrile hydratases with broad substrate specificity
JP5517610B2 (ja) * 2006-05-15 2014-06-11 エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング α−ヒドロキシカルボン酸エステルの製造法
DE102006025821A1 (de) * 2006-06-02 2007-12-06 Degussa Gmbh Ein Enzym zur Herstellung von Mehylmalonatsemialdehyd oder Malonatsemialdehyd
DE102006029320B3 (de) * 2006-06-23 2007-10-11 Röhm Gmbh Verfahren zur kontinuierlichen Herstellung von ungesättigten Carbonsäureanhydriden
DE102006029319A1 (de) * 2006-06-23 2007-12-27 Röhm Gmbh Verfahren zur Aufreinigung von polymerisierbaren Verbindungen
DE102006034273A1 (de) * 2006-07-21 2008-01-24 Röhm Gmbh Verfahren zur Herstellung von Alpha-Hydroxycarbonsäuren
DE102006055430A1 (de) 2006-11-22 2008-05-29 Evonik Röhm Gmbh Verfahren zur Herstellung von Carbonsäureamiden durch Hydrolyse von Carbonsäurenitrilen in Gegenwart eines Mangandioxid umfassenden Katalysators
DE102006055428A1 (de) 2006-11-22 2008-05-29 Evonik Röhm Gmbh Verfahren zur Herstellung von (Meth)acrylsäure
DE102006055427A1 (de) 2006-11-22 2008-05-29 Evonik Röhm Gmbh Verfahren zur Herstellung von Tetramethylglycolid
DE102006055426A1 (de) * 2006-11-22 2008-05-29 Evonik Röhm Gmbh Verfahren zur Herstellung von Alkyl(meth)acrylaten unter Verwendung einer enzymatischen Cyanhydrinhydrolyse
EP2130925A4 (en) * 2007-02-28 2011-06-01 Mitsubishi Gas Chemical Co PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINO ACID
US7943549B2 (en) * 2007-04-02 2011-05-17 Georgia State University Research Foundation, Inc. Biological-based catalyst to delay plant development processes
WO2010147642A1 (en) 2009-06-15 2010-12-23 Massachusetts Institute Of Technology Production of triacylglycerides, fatty acids, and their derivatives
CN103649312B (zh) 2011-05-31 2017-03-22 三菱丽阳株式会社 改良型腈水合酶
CN102517271B (zh) * 2011-12-13 2013-04-03 清华大学 一种突变腈水合酶
RU2520870C1 (ru) 2012-12-27 2014-06-27 Кемира Оюй Штамм бактерий rhodococcus aetherivorans bkm ac-2610d - продуцент нитрилгидратазы, способ его культивирования и способ получения акриламида
RU2562822C2 (ru) * 2014-01-09 2015-09-10 Общество с ограниченной ответственностью "Спектралазер" Газотурбинный авиационный двигатель и способ его форсирования
CN107177581B (zh) * 2017-06-16 2020-04-28 清华大学 一种改造腈水合酶及其应用
EP4105335A1 (en) 2021-06-16 2022-12-21 Evonik Operations GmbH Enzymatic method for the production of l-glufosinate p-alkyl esters
EP4493709A1 (en) 2022-03-14 2025-01-22 Evonik Operations GmbH Enzymatic method for the production of l-glufosinate p-esters

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ280901B6 (cs) 1988-10-06 1996-05-15 Hideaki Yamada Způsob kultivace bakterií
JP2907479B2 (ja) * 1990-02-28 1999-06-21 輝彦 別府 ニトリルヒドラターゼ活性を有するポリペプチドをコードする遺伝子ｄｎａ、これを含有する形質転換体及びアミド類の製造法
US5789211A (en) * 1991-05-02 1998-08-04 Nitto Chemical Industry Co., Ltd. Gene encoding a polypeptide having nitrile hydratase activity, a transformant containing the gene and a process for the production of amides using the transformant
JPH05284982A (ja) 1992-04-08 1993-11-02 Japan Energy Corp 微生物によるラセミ化２−アミノニトリルの製造法
DE69739026D1 (de) * 1996-02-14 2008-11-20 Mitsui Chemicals Inc Nitril-Hydratase, ihre Derivate und Verfahren zur Herstellung von Verbindungen
US5866379A (en) 1997-01-28 1999-02-02 Novus International Enzymatic conversion of α-hydroxynitriles to the corresponding .alpha.
JP4185607B2 (ja) * 1998-12-15 2008-11-26 ダイセル化学工業株式会社 新規な微生物及びアミド化合物の製造方法
WO2001060789A1 (en) 2000-02-15 2001-08-23 Rhone-Poulenc Animal Nutrition Process for the production of methionine
MX268424B (es) 2001-01-09 2009-07-17 Lonza Ag Procedimiento microbiologico para la produccion de amidas.
JP2002325587A (ja) * 2001-03-02 2002-11-12 Daicel Chem Ind Ltd ニトリルヒドラターゼ、およびアミドの製造方法
DE10155928A1 (de) 2001-11-15 2003-06-12 Degussa recA-negativer und rhaB-negativer Mikroorganismus

Also Published As

Publication number Publication date
EP1730291A2 (de) 2006-12-13
WO2005093080A3 (de) 2006-04-27
CN1930299B (zh) 2011-04-06
US7288402B2 (en) 2007-10-30
CN1930299A (zh) 2007-03-14
RU2385932C2 (ru) 2010-04-10
US7491521B2 (en) 2009-02-17
RU2006137033A (ru) 2008-04-27
US20080057549A1 (en) 2008-03-06
EP1730291B1 (de) 2012-12-05
US20060068467A1 (en) 2006-03-30
DE102004013824A1 (de) 2005-10-13
JP5080240B2 (ja) 2012-11-21
ES2400360T3 (es) 2013-04-09
JP2007529231A (ja) 2007-10-25
WO2005093080A2 (de) 2005-10-06

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Legal Events

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B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired