BRPI0509740A - compostos para tratamento das arritmias cardìacas e métodos de uso - Google Patents

compostos para tratamento das arritmias cardìacas e métodos de uso

Info

Publication number
BRPI0509740A
BRPI0509740A BRPI0509740-1A BRPI0509740A BRPI0509740A BR PI0509740 A BRPI0509740 A BR PI0509740A BR PI0509740 A BRPI0509740 A BR PI0509740A BR PI0509740 A BRPI0509740 A BR PI0509740A
Authority
BR
Brazil
Prior art keywords
methods
treatment
compounds
cardiac arrhythmias
cardiac
Prior art date
Application number
BRPI0509740-1A
Other languages
English (en)
Inventor
Pascal Druzgala
Original Assignee
Aryx Therapeutics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aryx Therapeutics filed Critical Aryx Therapeutics
Publication of BRPI0509740A publication Critical patent/BRPI0509740A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

COMPOSTOS PARA TRATAMENTO DAS ARRITMIAS CARDìACAS E MéTODOS DE USO. A presente invenção refere-se a novos compostos para tratamento de arritmia cardíaca e métodos de uso.
BRPI0509740-1A 2004-04-09 2005-04-08 compostos para tratamento das arritmias cardìacas e métodos de uso BRPI0509740A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56091704P 2004-04-09 2004-04-09
PCT/US2005/012138 WO2005099684A1 (en) 2004-04-09 2005-04-08 Benzofuranyl derivatives useful for the treatment of cardiac arrhythmia

Publications (1)

Publication Number Publication Date
BRPI0509740A true BRPI0509740A (pt) 2007-09-25

Family

ID=34965215

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0509740-1A BRPI0509740A (pt) 2004-04-09 2005-04-08 compostos para tratamento das arritmias cardìacas e métodos de uso

Country Status (14)

Country Link
US (3) US7105568B2 (pt)
EP (1) EP1732537A1 (pt)
JP (1) JP2007532576A (pt)
KR (1) KR20070001259A (pt)
CN (1) CN1950080A (pt)
AU (1) AU2005232701A1 (pt)
BR (1) BRPI0509740A (pt)
CA (1) CA2560336A1 (pt)
IL (1) IL178127A0 (pt)
MX (1) MXPA06011647A (pt)
NO (1) NO20065156L (pt)
RU (1) RU2373199C2 (pt)
WO (1) WO2005099684A1 (pt)
ZA (1) ZA200607666B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005232701A1 (en) * 2004-04-09 2005-10-27 Aryx Therapeutics Benzofuranyl derivatives useful for the treatment of cardiac arrhytmia
RU2446143C2 (ru) * 2010-05-19 2012-03-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" (ЯГТУ) Способ получения эфиров замещенных 5,6-дицианобензофуран-2-карбоновых кислот
CN108396016B (zh) * 2018-02-05 2021-05-25 中国科学院南海海洋研究所 一种酯酶phe21及其编码基因和在手性乙酸仲丁酯制备中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2550091B1 (fr) 1983-08-02 1986-05-23 Sanofi Sa Composition pharmaceutique ou veterinaire destinee a combattre des troubles ischemiques cardiaques contenant un derive du benzofuranne
US5175187A (en) * 1989-03-06 1992-12-29 Soorianarain Baligadoo Synergistic compositions for the treatment of coronary insufficiency and methods of use thereof
US5364880A (en) * 1993-06-16 1994-11-15 Advanced Therapies, Inc. Compound for treatment of cardiac arrhythmia, synthesis, and methods of use
US6309823B1 (en) * 1993-10-26 2001-10-30 Affymetrix, Inc. Arrays of nucleic acid probes for analyzing biotransformation genes and methods of using the same
US6121278A (en) * 1997-09-03 2000-09-19 Guilford Pharmaceuticals, Inc. Di-n-heterocyclic compounds, methods, and compositions for inhibiting parp activity
RU2138492C1 (ru) * 1997-12-23 1999-09-27 Пятигорская государственная фармацевтическая академия Способ синтеза производных 3-(5-метилфур-2-ил)-бензофурана, обладающих гипотензивной, антиангинальной и антиаритмической активностями
PT1222180E (pt) 1999-10-15 2007-09-20 Aryx Therapeutics Compostos enantioméricos para o tratamento de arritmias cardíacas e métodos de utilização
WO2003050102A1 (en) 2001-12-10 2003-06-19 Aryx Therapeutics Novel compounds for the treatment of cardiac arrhythmia, synthesis, and methods of use
US7015568B2 (en) * 2003-08-21 2006-03-21 Texas Instruments Incorporated System for ultraviolet atmospheric seed layer remediation
AU2005232701A1 (en) * 2004-04-09 2005-10-27 Aryx Therapeutics Benzofuranyl derivatives useful for the treatment of cardiac arrhytmia

Also Published As

Publication number Publication date
NO20065156L (no) 2006-11-09
EP1732537A1 (en) 2006-12-20
WO2005099684A1 (en) 2005-10-27
AU2005232701A1 (en) 2005-10-27
RU2373199C2 (ru) 2009-11-20
JP2007532576A (ja) 2007-11-15
US7351842B2 (en) 2008-04-01
MXPA06011647A (es) 2007-04-13
RU2006139649A (ru) 2008-05-20
US20080114059A1 (en) 2008-05-15
US20050228045A1 (en) 2005-10-13
ZA200607666B (en) 2008-03-26
US20060276535A1 (en) 2006-12-07
KR20070001259A (ko) 2007-01-03
IL178127A0 (en) 2006-12-31
US7105568B2 (en) 2006-09-12
CN1950080A (zh) 2007-04-18
CA2560336A1 (en) 2005-10-27

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.