BRPI0510175A - composições farmacêuticas comprimidas - Google Patents

composições farmacêuticas comprimidas

Info

Publication number
BRPI0510175A
BRPI0510175A BRPI0510175-1A BRPI0510175A BRPI0510175A BR PI0510175 A BRPI0510175 A BR PI0510175A BR PI0510175 A BRPI0510175 A BR PI0510175A BR PI0510175 A BRPI0510175 A BR PI0510175A
Authority
BR
Brazil
Prior art keywords
compressed pharmaceutical
polyethylene glycol
pharmaceutical compositions
pharmaceutical composition
agreeable
Prior art date
Application number
BRPI0510175-1A
Other languages
English (en)
Inventor
Norman Barras
Ian Cox
Original Assignee
Norgine Europe Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norgine Europe Bv filed Critical Norgine Europe Bv
Publication of BRPI0510175A publication Critical patent/BRPI0510175A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/77—Polymers containing oxygen of oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

COMPOSIçõES FARMACêUTICAS COMPRIMIDAS.A presente invenção fornece uma composição farmacêutica comprimida contendo polietileno glicol de peso molecular de 2000 a 4500, em que o polietileno glicol constitui de 80 a 99,5% em peso da composição, um ou mais eletrólitos para o tratamento da constipação, impacção fecal, retenção fecal, cólica e gás intestinal ou flatulência ou para lavagem ortostática, evacuação do cólon ou limpeza do cólon.Verificou-se, surpreendentemente, que uma composição farmacêutica comprimida contendo PEG, por exemplo, um comprimido sólido, é significativamente mais palatável do que as composições propostas anteriormente e é eficaz quando administrada. Verificou-se que a composição farmacêutica comprimida da invenção contendo polietileno glicol tem um sabor mais agradável e uma sensação mais agradável na boca do que as omposições líquidas, ou em pó seco ou granulares anteriormente propostas.
BRPI0510175-1A 2004-04-23 2005-04-25 composições farmacêuticas comprimidas BRPI0510175A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0409104.7A GB0409104D0 (en) 2004-04-23 2004-04-23 Compressed pharmaceutical compositions
PCT/GB2005/001555 WO2005102364A1 (en) 2004-04-23 2005-04-25 Compressed pharmaceutical compositions comprising peg and electrolytes

Publications (1)

Publication Number Publication Date
BRPI0510175A true BRPI0510175A (pt) 2007-10-02

Family

ID=32344298

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510175-1A BRPI0510175A (pt) 2004-04-23 2005-04-25 composições farmacêuticas comprimidas

Country Status (22)

Country Link
US (1) US20070298100A1 (pt)
EP (2) EP2263680B1 (pt)
JP (1) JP2007533719A (pt)
KR (1) KR20070001280A (pt)
CN (1) CN1950097A (pt)
AT (1) ATE496626T1 (pt)
AU (1) AU2005235345B8 (pt)
BR (1) BRPI0510175A (pt)
CA (1) CA2561649C (pt)
DE (1) DE602005026117D1 (pt)
DK (2) DK1742645T3 (pt)
ES (2) ES2519540T3 (pt)
GB (1) GB0409104D0 (pt)
IL (1) IL178722A0 (pt)
MX (1) MXPA06011906A (pt)
NO (1) NO20064780L (pt)
PL (2) PL1742645T3 (pt)
PT (2) PT2263680E (pt)
RU (1) RU2006137347A (pt)
SI (2) SI1742645T1 (pt)
WO (1) WO2005102364A1 (pt)
ZA (1) ZA200608496B (pt)

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JP5276435B2 (ja) * 2005-05-06 2013-08-28 セイリックス ファーマシューティカルズ， インコーポレイティッド ポリエチレングリコールの結腸の下剤組成物
ES2278537B1 (es) * 2006-01-30 2008-09-16 Laboratorios Casen-Fleet, S.L. Procedimiento de fabricacion de una solucion a base de polietilenglicol con electrolitos, producto obtenido y uso.
US8784872B2 (en) * 2007-11-19 2014-07-22 Comgenrx, Inc. Formulation for decreasing tobacco, alcohol, drug or food consumption
US20090130048A1 (en) * 2007-11-19 2009-05-21 Oronsky Bryan Todd Topical Composition for Treating Pain
SI2304146T1 (sl) 2008-06-06 2014-04-30 Roto Frank Ag Preklopna naprava za odpiranje okna, vrat ali podobnega
WO2009158667A2 (en) * 2008-06-27 2009-12-30 Comgenrx, Inc. Povidone compositions for wound healing
AU2010239378B2 (en) * 2009-04-21 2013-11-21 Dark Canyon Laboratories, Llc Colon lavage system
EP2438077B1 (en) * 2009-06-03 2013-12-04 Aptalis Pharma U.S. Inc. L-sugar colon cleansing agent and uses thereof
GB0913295D0 (en) 2009-07-30 2009-09-02 Norgine Bv Improvements in and relating to pharmaceutical compositions
AU2010328366A1 (en) * 2009-12-07 2012-06-21 Aptalis Pharma Us, Inc Methods for purifying monosaccharide mixtures containing ionic impurities
CN101766648B (zh) * 2010-03-02 2012-01-11 舒泰神（北京）生物制药股份有限公司 聚乙二醇电解质颗粒制剂及其制造方法
DE202010012256U1 (de) * 2010-09-07 2010-11-11 Krewel Meuselbach Gmbh Abführmittel
DE202010016235U1 (de) 2010-12-06 2011-05-19 Norgine B.V. Formulierungen
NL2007716C2 (en) * 2010-11-04 2012-11-13 Norgine Bv Formulations.
AU2011100528B4 (en) * 2011-05-10 2011-08-25 Norgine Bv Formulations
FR2967069B3 (fr) * 2010-11-04 2012-11-16 Norgine Bv Formulations
BR112013019360A2 (pt) 2011-01-28 2017-03-28 A Shaver William ingredientes, componente seco de formulação oral de baixo teor de cloreto farmaceuticamente aceitável para limpeza de cólon, solução de base de reposição de eletrólito aquosa para uso em lavagem colônica, métodos para limpar os intestinos de paciente, para preparar solução aquosa para limpeza do cólon e para aumentar substancialmente o paladar de limpador de cólon e kits para evacuação do cólon.
BR112013019418B1 (pt) * 2011-01-31 2022-03-29 Norgine Bv Solução aquosa de peg, seus usos no tratamento de constipação e/ou impactação fecal e kit
TWI535461B (zh) 2011-03-11 2016-06-01 諾金私人有限公司 結腸清潔溶液、用於製備該溶液之組成物、包含該組成物或溶液之套組、與製備該溶液之方法
CN102133225B (zh) * 2011-03-18 2012-11-21 海南锦瑞制药股份有限公司 一种复方聚乙二醇电解质散剂及其制备方法
BR112014009946A2 (pt) * 2011-10-27 2017-04-25 Salix Pharmaceuticals Inc "composição, composição farmacêutica ou formulação purgativas e uso das mesmas"
CN102600201B (zh) * 2012-02-07 2014-07-16 舒泰神（北京）生物制药股份有限公司 用于通便和清肠的药物组合物及其制备方法
KR20170098980A (ko) 2012-09-11 2017-08-30 노어긴 비.브이. Peg 및 아스코르베이트를 포함하는 조성물
EP3563838A1 (en) * 2013-03-15 2019-11-06 Braintree Laboratories, Inc. Dual use oral pharmaceutical composition tablets of suflate salts and methods of use thereof
JP2017514521A (ja) * 2014-04-29 2017-06-08 コロナリーコンセプツ エルエルシー 電解質補給物をもたらすための食品、システム、方法、及びキット
US10350165B2 (en) 2014-12-12 2019-07-16 Ojai Energetics Pbc Methods and systems for forming stable droplets
JP2018505912A (ja) * 2014-12-12 2018-03-01 オーハイ エナジェティクス ピービーシー マイクロカプセル化カンナビノイド組成物
FR3056109B1 (fr) 2016-09-21 2019-10-11 Pierre Fabre Medicament Utilisation de formulations solides de polyethylene glycol dans le traitement de la constipation
CN107028876B (zh) * 2016-10-09 2020-09-29 舒泰神（北京）生物制药股份有限公司 聚乙二醇电解质口服液及其制备方法
JP7475270B2 (ja) 2017-07-20 2024-04-26 ソルヴェイ（ソシエテ アノニム） 発泡剤としての官能化微粒子重炭酸塩、それを含有する発泡性ポリマー組成物、及び熱可塑性発泡ポリマーの製造でのその使用
WO2019151829A1 (ko) * 2018-02-01 2019-08-08 주식회사태준제약 장세척 조성물
KR20190093491A (ko) 2018-02-01 2019-08-09 주식회사태준제약 장세척 조성물
CN110433174A (zh) * 2019-07-17 2019-11-12 华南理工大学 一种高依从性的复方聚乙二醇电解质散剂及其制备方法与应用
CN111617102B (zh) * 2020-05-25 2022-05-31 南京金凯木纳米材料有限公司 一种含聚乙二醇的电解质散剂及其制备方法
KR20230124560A (ko) * 2020-10-26 2023-08-25 브레인트리 라보라토리이즈, 인코포레이티드 결장 세정을 위한 술페이트 염 제제

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US3121663A (en) * 1956-02-09 1964-02-18 Plough Lab Inc Carbon dioxide releasing laxative suppository
US5229132A (en) * 1985-02-22 1993-07-20 Grimberg Georges Serge Non-absorbable gastrointestinal medicament provided for treating the two levels of the digestive tract at the same time
JP2509594B2 (ja) * 1985-08-01 1996-06-19 ブレインツリ−・ラボラトリ−ズ・インコ−ポレ−テッド 低ナトリウム緩下剤および洗浄剤処方
US5273758A (en) * 1991-03-18 1993-12-28 Sandoz Ltd. Directly compressible polyethylene oxide vehicle for preparing therapeutic dosage forms
US6121663A (en) * 1997-05-22 2000-09-19 Advanced Micro Devices, Inc. Local interconnects for improved alignment tolerance and size reduction
FR2784897B1 (fr) * 1998-10-27 2002-11-29 Agronomique Inst Nat Rech Utilisation d'un laxatif osmotique non fermente dans le traitement et la prevention des cancers colorectaux
US6444198B1 (en) * 1999-02-22 2002-09-03 Smithkline Beecham Corporation Effervescent laxatives
DE19933148A1 (de) * 1999-07-20 2001-01-25 Boehringer Ingelheim Int Ambroxolhaltige Lutschtablette
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US7687075B2 (en) * 2003-11-19 2010-03-30 Salix Pharmaceuticals, Ltd. Colonic purgative composition with soluble binding agent

Also Published As

Publication number Publication date
US20070298100A1 (en) 2007-12-27
NO20064780L (no) 2007-01-18
AU2005235345B8 (en) 2011-05-12
JP2007533719A (ja) 2007-11-22
KR20070001280A (ko) 2007-01-03
ES2519540T3 (es) 2014-11-07
GB0409104D0 (en) 2004-05-26
PT2263680E (pt) 2014-11-19
AU2005235345A1 (en) 2005-11-03
ZA200608496B (en) 2008-07-30
DK2263680T3 (en) 2014-12-08
ATE496626T1 (de) 2011-02-15
SI2263680T1 (sl) 2015-01-30
CN1950097A (zh) 2007-04-18
IL178722A0 (en) 2007-02-11
PL2263680T3 (pl) 2015-02-27
RU2006137347A (ru) 2008-05-27
EP1742645B1 (en) 2011-01-26
SI1742645T1 (sl) 2011-05-31
MXPA06011906A (es) 2007-01-25
AU2005235345B2 (en) 2011-04-14
EP2263680B1 (en) 2014-08-27
DK1742645T3 (da) 2011-05-09
EP1742645A1 (en) 2007-01-17
PL1742645T3 (pl) 2011-06-30
EP2263680A1 (en) 2010-12-22
CA2561649A1 (en) 2005-11-03
WO2005102364A1 (en) 2005-11-03
DE602005026117D1 (de) 2011-03-10
CA2561649C (en) 2014-10-14
PT1742645E (pt) 2011-04-29
ES2361816T3 (es) 2011-06-22

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: NORGINE BV (NL)

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 11A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2385 DE 20-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.