BRPI0510370A - derivados de ácido fenoxi-alquil-carboxìlico no tratamento de doenças inflamatórias - Google Patents

derivados de ácido fenoxi-alquil-carboxìlico no tratamento de doenças inflamatórias

Info

Publication number
BRPI0510370A
BRPI0510370A BRPI0510370-3A BRPI0510370A BRPI0510370A BR PI0510370 A BRPI0510370 A BR PI0510370A BR PI0510370 A BRPI0510370 A BR PI0510370A BR PI0510370 A BRPI0510370 A BR PI0510370A
Authority
BR
Brazil
Prior art keywords
treatment
carboxylic acid
acid derivatives
inflammatory diseases
phenoxyalkyl carboxylic
Prior art date
Application number
BRPI0510370-3A
Other languages
English (en)
Inventor
Charles Smith
Kenneth Walter Locke
Taka Kiyoizumi
Original Assignee
Medicinova Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicinova Inc filed Critical Medicinova Inc
Publication of BRPI0510370A publication Critical patent/BRPI0510370A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

DERIVADOS DE áCIDO FENOXI-ALQUIL-CARBOXìLICO NO TRATAMENTO DE DOENçAS INFLAMATóRIAS. A presente invenção refere-se a um método para tratar cistite intersticial, síndrome de intestino irritável, colite ulcerativa, e outras condições inflamatórias, que compreende: administrar em um paciente necessitado do mesmo uma quantidade eficaz de um composto selecionado a partir de composto 1, seu metabolito 2 e sais ou pró-fármacos farmaceuticamente aceitáveis do mesmo.
BRPI0510370-3A 2004-04-27 2005-04-27 derivados de ácido fenoxi-alquil-carboxìlico no tratamento de doenças inflamatórias BRPI0510370A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56552704P 2004-04-27 2004-04-27
PCT/US2005/014545 WO2005105073A1 (en) 2004-04-27 2005-04-27 Phenoxyalkycarboxylic acid derivatives in the treatment of inflammatory diseases

Publications (1)

Publication Number Publication Date
BRPI0510370A true BRPI0510370A (pt) 2007-11-06

Family

ID=35241416

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510370-3A BRPI0510370A (pt) 2004-04-27 2005-04-27 derivados de ácido fenoxi-alquil-carboxìlico no tratamento de doenças inflamatórias

Country Status (13)

Country Link
US (3) US7429617B2 (pt)
EP (1) EP1744740A4 (pt)
JP (1) JP2007534771A (pt)
KR (1) KR20070058381A (pt)
CN (1) CN101014331A (pt)
AU (1) AU2005237607B2 (pt)
BR (1) BRPI0510370A (pt)
CA (1) CA2564731A1 (pt)
MX (1) MXPA06012564A (pt)
NO (1) NO20065453L (pt)
NZ (1) NZ550809A (pt)
RU (1) RU2388466C2 (pt)
WO (1) WO2005105073A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10232113A1 (de) 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
DE102005009240A1 (de) 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften
CA2623657A1 (en) * 2005-09-29 2007-04-12 Bayer Healthcare Ag Pde inhibitors and combinations thereof for the treatment of urological disorders
JP2013119550A (ja) * 2011-12-08 2013-06-17 Medicinova Inc 非アルコール性脂肪性肝疾患及び非アルコール性脂肪性肝炎の処置方法
MX358211B (es) * 2012-07-23 2018-08-10 Landsteiner Scient S A De C V Una composición farmacéutica de liberación comprendiendo hidroclorotiazida, losartán y basilato de amlodipino.
WO2014142938A1 (en) * 2013-03-15 2014-09-18 Aihol Corporation Pharmaceutical formulation containing glycosaminoglycan
WO2015013395A1 (en) * 2013-07-25 2015-01-29 Medicinova, Inc. Methods for reducing triglyceride, total cholesterol and low density lipoprotein blood levels
US9346754B2 (en) * 2014-05-08 2016-05-24 Medicinova, Inc. Method of treating advanced non-alcoholic steatohepatitis
US20150321989A1 (en) * 2014-05-08 2015-11-12 Medicinova, Inc. Method of treating idiopathic pulmonary fibrosis
CA2950909C (en) * 2014-06-02 2023-03-28 Medicinova, Inc. Method of inhibiting or treating fibrosis
WO2016085954A1 (en) * 2014-11-26 2016-06-02 Medicinova, Inc. Geranygeranylacetone and analogs thereof and phenoxyalkylcarboxlic acids for treating fibrosis
KR20180011840A (ko) * 2015-06-12 2018-02-02 비샬 자조디아 스와티 방광 출구 폐쇄 및/또는 하부 요로 증상의 치료에서 사용하기 위한 펜토산폴리설페이트나트륨을 포함하는 조성물
US12514897B2 (en) * 2017-06-02 2026-01-06 Goodgut S.L. Grape skin for use in the treatment of dysbiosis

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4428935A (en) 1982-05-24 1984-01-31 Pfizer Inc. Penicillanic acid dioxide prodrug
FR2585246A1 (fr) 1985-07-26 1987-01-30 Cortial Procede d'obtention de formes pharmaceutiques solides a liberation prolongee
US4788055A (en) 1985-12-09 1988-11-29 Ciba-Geigy Corporation Resinate sustained release dextromethorphan composition
GB8613689D0 (en) 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
GB8613688D0 (en) 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
US4816264A (en) 1986-06-06 1989-03-28 Warner-Lambert Company Sustained release formulations
US4985585A (en) * 1988-03-07 1991-01-15 Kyorin Pharmaceutical Co., Ltd. Phenoxyalkylcarboxylic acid derivatives and process for their preparations
JPH07116125B2 (ja) * 1988-03-07 1995-12-13 杏林製薬株式会社 フェノキシアルキルカルボン酸誘導体及びその製造法
US4996047A (en) 1988-11-02 1991-02-26 Richardson-Vicks, Inc. Sustained release drug-resin complexes
CA2002492A1 (en) 1988-11-11 1990-05-11 Sandra T. A. Malkowska Pharmaceutical ion exchange resin composition
US5133974A (en) 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
JPH0551359A (ja) * 1991-01-18 1993-03-02 Kyorin Pharmaceut Co Ltd フエノキシアルキルカルボン酸誘導体及びその製造法
US5290812A (en) 1991-01-18 1994-03-01 Kyorin Pharmaceutical Co., Ltd. Phenoxyalkylcarboxylic acid derivatives and process of preparing the same
FI97934C (fi) * 1994-05-04 1997-03-10 Nokia Telecommunications Oy Kutsunsiirtomenetelmä ja -järjestely matkaviestimelle päättyvän puhelun yhteydessä
US6417186B1 (en) * 2000-11-14 2002-07-09 Syntex (U.S.A.) Llc Substituted-phenyl ketone derivatives as IP antagonists
US7060854B2 (en) 2003-06-24 2006-06-13 Medicinova, Inc. Process for making polymorphic form A of 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid
US7064146B2 (en) 2003-06-24 2006-06-20 Medicinova, Inc. Pharmaceutical compositions of isolated orthorhombic crystalline 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid and methods of use

Also Published As

Publication number Publication date
US20090093545A1 (en) 2009-04-09
NO20065453L (no) 2007-01-17
EP1744740A1 (en) 2007-01-24
US8026282B2 (en) 2011-09-27
EP1744740A4 (en) 2009-06-17
CA2564731A1 (en) 2005-11-10
US7786169B2 (en) 2010-08-31
WO2005105073A1 (en) 2005-11-10
CN101014331A (zh) 2007-08-08
KR20070058381A (ko) 2007-06-08
US20100285074A1 (en) 2010-11-11
RU2388466C2 (ru) 2010-05-10
AU2005237607A1 (en) 2005-11-10
MXPA06012564A (es) 2007-01-31
NZ550809A (en) 2010-07-30
AU2005237607B2 (en) 2010-12-16
US20050239902A1 (en) 2005-10-27
JP2007534771A (ja) 2007-11-29
US7429617B2 (en) 2008-09-30
RU2006141647A (ru) 2008-06-10

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.