BRPI0510648A - sistemas e métodos para biorreator descartável - Google Patents

sistemas e métodos para biorreator descartável

Info

Publication number
BRPI0510648A
BRPI0510648A BRPI0510648-6A BRPI0510648A BRPI0510648A BR PI0510648 A BRPI0510648 A BR PI0510648A BR PI0510648 A BRPI0510648 A BR PI0510648A BR PI0510648 A BRPI0510648 A BR PI0510648A
Authority
BR
Brazil
Prior art keywords
container
disposable
biomaterials
systems
methods
Prior art date
Application number
BRPI0510648-6A
Other languages
English (en)
Inventor
Geoffrey Hodge
Parrish Galliher
Michael Fisher
Original Assignee
Xcellerex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35197799&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0510648(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Xcellerex Inc filed Critical Xcellerex Inc
Publication of BRPI0510648A publication Critical patent/BRPI0510648A/pt
Publication of BRPI0510648B1 publication Critical patent/BRPI0510648B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/453—Magnetic mixers; Mixers with magnetically driven stirrers using supported or suspended stirring elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/50—Mixing receptacles
    • B01F35/513—Flexible receptacles, e.g. bags supported by rigid containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/50—Mixing receptacles
    • B01F35/53—Mixing receptacles characterised by the configuration of the interior, e.g. baffles for facilitating the mixing of components
    • B01F35/531—Mixing receptacles characterised by the configuration of the interior, e.g. baffles for facilitating the mixing of components with baffles, plates or bars on the wall or the bottom
    • B01F35/5312—Mixing receptacles characterised by the configuration of the interior, e.g. baffles for facilitating the mixing of components with baffles, plates or bars on the wall or the bottom with vertical baffles mounted on the walls
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/14—Bags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02—Stirrer or mobile mixing elements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/18—Flow directing inserts
    • C12M27/20—Baffles; Ribs; Ribbons; Auger vanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/44—Mixing of ingredients for microbiology, enzymology, in vitro culture or genetic manipulation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Computer Hardware Design (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
  • Packages (AREA)

Abstract

SISTEMAS E MéTODOS PARA BIORREATOR DESCARTáVEL. A presente invenção refere-se, conseqüentemente, a um sistema biorreator que inclui um recipiente descartável para abrigar biomateriais para processamento, o recipiente biodescartável incluindo pelo menos uma abertura de admissão, pelo menos uma abertura de descarga, pelo menos uma abertura de coleta, e a integridade do ambiente estéril é protegida com filtros estéreis presos a todas as aberturas externas abertas, uma estrutura para suportar o recipiente descartável, ou um ou mais sensores para sensoriar um ou mais parâmetros dos biomateriais no recipiente, um aquecedor para aquecer o conteúdo do recipiente, o aquecedor tendo um termostato e sistema de mistura arranjados com o sistema, de tal modo que os biomateriais contidos no recipiente descartável sejam misturados.
BRPI0510648A 2004-06-04 2005-06-06 biorreator descartável. BRPI0510648B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57714304P 2004-06-04 2004-06-04
US66925205P 2005-04-07 2005-04-07
PCT/US2005/020083 WO2005118771A2 (en) 2004-06-04 2005-06-06 Disposable bioreactor systems and methods

Publications (2)

Publication Number Publication Date
BRPI0510648A true BRPI0510648A (pt) 2007-11-20
BRPI0510648B1 BRPI0510648B1 (pt) 2016-04-26

Family

ID=35197799

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510648A BRPI0510648B1 (pt) 2004-06-04 2005-06-06 biorreator descartável.

Country Status (14)

Country Link
US (1) US7629167B2 (pt)
EP (1) EP1773976B2 (pt)
JP (1) JP4680990B2 (pt)
KR (1) KR101021203B1 (pt)
CN (2) CN101001945B (pt)
AU (1) AU2005250500B2 (pt)
BR (1) BRPI0510648B1 (pt)
CA (1) CA2569405C (pt)
CR (1) CR8769A (pt)
DK (1) DK1773976T4 (pt)
ES (1) ES2612212T5 (pt)
MX (1) MXPA06014099A (pt)
NO (1) NO20070069L (pt)
WO (1) WO2005118771A2 (pt)

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CA2569405A1 (en) 2005-12-15
CN101001945A (zh) 2007-07-18
AU2005250500A1 (en) 2005-12-15
KR20070053200A (ko) 2007-05-23
NO20070069L (no) 2007-03-05
HK1112479A1 (en) 2008-09-05
AU2005250500B2 (en) 2011-06-23
KR101021203B1 (ko) 2011-03-11
US20050272146A1 (en) 2005-12-08
CN102492607B (zh) 2014-12-10
WO2005118771A2 (en) 2005-12-15
WO2005118771A3 (en) 2006-02-02
ES2612212T3 (es) 2017-05-12
CA2569405C (en) 2011-05-03
CN102492607A (zh) 2012-06-13
ES2612212T5 (es) 2020-06-25
DK1773976T3 (en) 2017-01-30
CN101001945B (zh) 2012-02-08
MXPA06014099A (es) 2007-05-09
US7629167B2 (en) 2009-12-08
JP4680990B2 (ja) 2011-05-11
EP1773976B1 (en) 2016-12-07
CR8769A (es) 2007-08-28
BRPI0510648B1 (pt) 2016-04-26
EP1773976A2 (en) 2007-04-18
EP1773976B2 (en) 2020-01-01
DK1773976T4 (da) 2020-02-10

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