BRPI0510760A - método para administrar a um paciente uma composição, composição tópica, e, emplastro - Google Patents
método para administrar a um paciente uma composição, composição tópica, e, emplastroInfo
- Publication number
- BRPI0510760A BRPI0510760A BRPI0510760-1A BRPI0510760A BRPI0510760A BR PI0510760 A BRPI0510760 A BR PI0510760A BR PI0510760 A BRPI0510760 A BR PI0510760A BR PI0510760 A BRPI0510760 A BR PI0510760A
- Authority
- BR
- Brazil
- Prior art keywords
- composition
- propynoperhydropurine
- tricyclic
- effective amount
- pharmaceutical compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 230000000699 topical effect Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 4
- 230000005540 biological transmission Effects 0.000 abstract 2
- 239000002131 composite material Substances 0.000 abstract 2
- 230000002452 interceptive effect Effects 0.000 abstract 2
- 230000001537 neural effect Effects 0.000 abstract 2
- 238000013271 transdermal drug delivery Methods 0.000 abstract 2
- 239000006071 cream Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000001815 facial effect Effects 0.000 abstract 1
- 238000002676 facial rejuvenation Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Birds (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
Abstract
MéTODO PARA ADMNISTRAR A UM PACIENTE UMA COMPOSIçãO, COMPOSIçãO TóPICA, E, EMPLASTRO Composições farmacêuticas para interferir com a transmissão neuronal compreendendo uma quantidade eficaz de pelo menos uma 3,4-propinoperidropurina tricíclica são divulgadas. Preparações para o rejuvenescimento facial são fornecidas que compreendem uma quantidade eficaz da composição da invenção e um creme facial. Métodos de interferir com a transmissão neuronal que compreende a aplicação tópica de uma quantidade eficaz das composições farmacêuticas da invenção são fornecidos. Em um outro aspecto da invenção, quantidades eficazes das composições farmacêuticas e um sistema terapêutico transdérmico são fornecidos para a administração transdérmica de pelo menos uma 3,4-propinoperidropurina triciclica. A composição farmacêutica contém pelo menos uma 3,4-propinoperidropurina tricicica e pode ser formulada para a liberação de medicamento transdérmica. O sistema de liberação de medicamento transdérmica pode ser um compósito laminado que compreende uma camada de suporte, um reservatório de medicamento e um meio para prender o compósito à pele.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56911204P | 2004-05-07 | 2004-05-07 | |
| PCT/US2005/015819 WO2005110418A2 (en) | 2004-05-07 | 2005-05-06 | Transdermal administration of phycotoxins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0510760A true BRPI0510760A (pt) | 2007-11-20 |
Family
ID=35394660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0510760-1A BRPI0510760A (pt) | 2004-05-07 | 2005-05-06 | método para administrar a um paciente uma composição, composição tópica, e, emplastro |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8377951B2 (pt) |
| EP (1) | EP1796676B1 (pt) |
| JP (1) | JP2007538010A (pt) |
| CN (1) | CN101123967A (pt) |
| AU (1) | AU2005244096B2 (pt) |
| BR (1) | BRPI0510760A (pt) |
| CA (1) | CA2607206C (pt) |
| ES (1) | ES2568953T3 (pt) |
| MX (1) | MXPA06012960A (pt) |
| WO (1) | WO2005110418A2 (pt) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007536269A (ja) * | 2004-05-07 | 2007-12-13 | ファイトトックス リミテッド | ゴニオトキシンを用いた創傷の治療方法 |
| US9107815B2 (en) | 2008-02-22 | 2015-08-18 | Allergan, Inc. | Sustained release poloxamer containing pharmaceutical compositions |
| WO2009143174A2 (en) * | 2008-05-19 | 2009-11-26 | Children's Medical Center Corporation | Chemical permeation enhancers enhance nerve blockade by toxins |
| US8957207B2 (en) | 2009-03-24 | 2015-02-17 | Proteus S.A. | Methods for producing phycotoxins |
| US20120034296A1 (en) * | 2009-04-08 | 2012-02-09 | Massachusetts Institute Of Technology | Prolonged duration local anesthesia with minimal toxicity |
| CA2760946C (en) * | 2009-05-07 | 2019-06-25 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for studying, imaging, and treating pain |
| JP6112867B2 (ja) * | 2010-02-10 | 2017-04-12 | ファイトトックス リミテッドPhytotox Limited | サキシトキシン誘導体での触覚の喪失の処置 |
| WO2013122637A1 (en) * | 2012-02-17 | 2013-08-22 | Capriotti Joseph | Antifungal compositions for the treatment of skin and nails |
| EP2638908A1 (en) * | 2012-03-16 | 2013-09-18 | Phytotox SpA | Paralytic Shellfish Poison |
| US20130251770A1 (en) * | 2012-03-22 | 2013-09-26 | Revance Therapeutics, Inc. | Method of Treatment of Wrinkles Using Topical Chemodenervating Agents |
| RS58750B1 (sr) | 2013-03-15 | 2019-06-28 | Childrens Medical Ct Corp | Kombinovane formulacije neosaksitoksina za produženu lokalnu anesteziju |
| WO2015157559A2 (en) | 2014-04-09 | 2015-10-15 | Siteone Therapeutics, Inc. | 10',11'-modified saxitoxins for the treatment of pain |
| ES2895155T3 (es) | 2015-09-30 | 2022-02-17 | Siteone Therapeutics Inc | Saxitoxinas modificadas en 11,13 para el tratamiento del dolor |
| US20170209553A1 (en) | 2016-01-22 | 2017-07-27 | Transderm, Inc. | Delivery of botulinum with microneedle arrays |
| US11279706B2 (en) | 2017-03-29 | 2022-03-22 | Siteone Therapeutics, Inc. | 11,13-modified saxitoxins for the treatment of pain |
| CN110831945B (zh) | 2017-03-29 | 2023-08-08 | 赛特温治疗公司 | 用于治疗疼痛的11,13-修饰的石房蛤毒素类化合物 |
| US11338308B2 (en) * | 2018-08-09 | 2022-05-24 | Kao Corporation | Method for producing wearable coating |
| EP3860714B1 (en) | 2018-10-03 | 2023-09-06 | Siteone Therapeutics, Inc. | 11,13-modified saxitoxins for the treatment of pain |
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| US6432986B2 (en) | 1997-07-21 | 2002-08-13 | Bruce H. Levin | Compositions, kits, and methods for inhibiting cerebral neurovascular disorders and muscular headaches |
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| WO2000024419A1 (en) | 1998-10-27 | 2000-05-04 | Mayo Foundation For Medical Education And Research | Methods for enhancing wound healing |
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| CN1269482C (zh) | 2001-05-18 | 2006-08-16 | 威克斯医药有限公司 | 钠离子通道阻断剂和阿片类镇痛剂在制备用于对哺乳动物进行协同镇痛的药物中的应用 |
| MXPA04004543A (es) | 2001-11-15 | 2005-03-31 | Micro Algae Corp | Composiciones farmaceuticas que contienen 3,4-propinoperhidropurinas y sus usos para el bloqueo de la transmision neuronal. |
| CN1194693C (zh) | 2002-01-11 | 2005-03-30 | 中国科学院海洋研究所 | 麻痹性贝毒毒素作为制备疗治疼痛病症药物的应用 |
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-
2005
- 2005-05-06 JP JP2007511630A patent/JP2007538010A/ja active Pending
- 2005-05-06 ES ES05746905.8T patent/ES2568953T3/es not_active Expired - Lifetime
- 2005-05-06 AU AU2005244096A patent/AU2005244096B2/en not_active Ceased
- 2005-05-06 CN CNA2005800227688A patent/CN101123967A/zh active Pending
- 2005-05-06 EP EP05746905.8A patent/EP1796676B1/en not_active Expired - Lifetime
- 2005-05-06 BR BRPI0510760-1A patent/BRPI0510760A/pt not_active IP Right Cessation
- 2005-05-06 CA CA2607206A patent/CA2607206C/en not_active Expired - Lifetime
- 2005-05-06 MX MXPA06012960A patent/MXPA06012960A/es unknown
- 2005-05-06 WO PCT/US2005/015819 patent/WO2005110418A2/en not_active Ceased
- 2005-05-06 US US11/568,751 patent/US8377951B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN101123967A (zh) | 2008-02-13 |
| US8377951B2 (en) | 2013-02-19 |
| CA2607206A1 (en) | 2005-11-24 |
| EP1796676B1 (en) | 2016-03-09 |
| ES2568953T3 (es) | 2016-05-05 |
| EP1796676A2 (en) | 2007-06-20 |
| AU2005244096B2 (en) | 2011-03-17 |
| CA2607206C (en) | 2016-06-14 |
| JP2007538010A (ja) | 2007-12-27 |
| HK1109332A1 (zh) | 2008-06-06 |
| WO2005110418A3 (en) | 2007-06-07 |
| AU2005244096A1 (en) | 2005-11-24 |
| US20080045553A1 (en) | 2008-02-21 |
| MXPA06012960A (es) | 2007-06-12 |
| EP1796676A4 (en) | 2008-06-25 |
| WO2005110418A2 (en) | 2005-11-24 |
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