BRPI0512948A - biomarcadores de mal de alzheimer - Google Patents
biomarcadores de mal de alzheimerInfo
- Publication number
- BRPI0512948A BRPI0512948A BRPI0512948-6A BRPI0512948A BRPI0512948A BR PI0512948 A BRPI0512948 A BR PI0512948A BR PI0512948 A BRPI0512948 A BR PI0512948A BR PI0512948 A BRPI0512948 A BR PI0512948A
- Authority
- BR
- Brazil
- Prior art keywords
- alzheimer
- disease
- biomarkers
- test
- diagnosing
- Prior art date
Links
- 208000024827 Alzheimer disease Diseases 0.000 title abstract 4
- 239000000090 biomarker Substances 0.000 title abstract 2
- 102000002254 Glycogen Synthase Kinase 3 Human genes 0.000 abstract 1
- 108010014905 Glycogen Synthase Kinase 3 Proteins 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 208000010877 cognitive disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000027061 mild cognitive impairment Diseases 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
BIOMARCADORES DE MAL DE ALZHEIMER Um teste para diagnóstico de mal de Alzheimer compreende medição dos níveis de GSK-3 em células ou fluido corporal em uma amostra tomada de um ser humano. O teste proporciona um método relativamente não invasivo de diagnóstico de mal de Alzheimer e pode ser útil na previsão de quais indivíduos com dano cognitivo brando desenvolverão mal de Alzheimer.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0414894.6A GB0414894D0 (en) | 2004-07-02 | 2004-07-02 | Biomarkers of alzheimer's disease |
| PCT/GB2005/002592 WO2006003414A2 (en) | 2004-07-02 | 2005-07-01 | Biomarkers of alzheimer's disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0512948A true BRPI0512948A (pt) | 2008-04-15 |
Family
ID=32843494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0512948-6A BRPI0512948A (pt) | 2004-07-02 | 2005-07-01 | biomarcadores de mal de alzheimer |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20080076140A1 (pt) |
| EP (1) | EP1763674A2 (pt) |
| JP (1) | JP2008504551A (pt) |
| CN (1) | CN101010589A (pt) |
| AU (1) | AU2005258926A1 (pt) |
| BR (1) | BRPI0512948A (pt) |
| CA (1) | CA2571692A1 (pt) |
| GB (1) | GB0414894D0 (pt) |
| WO (1) | WO2006003414A2 (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8226927B2 (en) | 2006-05-25 | 2012-07-24 | Farhad Karimi | 11C/18F-labeled inhibitors of glycogen synthase kinase-3 |
| WO2009074331A2 (en) * | 2007-12-11 | 2009-06-18 | Julius-Maximilians-Universität Würzburg | Early and differential diagnosis test for alzheimer's disease |
| WO2009114945A1 (en) | 2008-03-21 | 2009-09-24 | Neuman Manuela G | Methods and kits for the differential diagnosis of alzheimer's disease versus frontotemporal dementia, and for the diagnosis of frontotemporal dementia, comprising fas-l and ckl 18 as biomarkers |
| US20100151457A1 (en) * | 2008-12-17 | 2010-06-17 | National Tsing Hua University | Detection of Unhealthy Cell and Uses Thereof |
| US20120040361A1 (en) * | 2010-07-22 | 2012-02-16 | National Tsing Hua University | Methods and compositions for detection of lethal system and uses thereof |
| CN104237526B (zh) * | 2013-06-18 | 2016-08-17 | 磁量生技股份有限公司 | 一种检测阿兹海默症罹患风险的系统 |
| CA2941650A1 (en) * | 2014-03-05 | 2015-09-11 | Humanetics Corporation | Predicting and reducing cognitive decline based on gsk-3 levels |
| CN104698188A (zh) * | 2015-03-04 | 2015-06-10 | 华中科技大学 | 检测人血小板GSK-3β蛋白活性的斑点印迹方法 |
| CN111323597A (zh) * | 2018-12-14 | 2020-06-23 | 陈志成 | 用于检测受试者中mci和/或ad的方法、试剂盒及筛选化合物的方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2569083A1 (en) * | 2004-05-07 | 2005-11-17 | Garvan Institute Of Medical Research | Detecting disease association with aberrant glycogen synthase kinase 3.beta. expression |
-
2004
- 2004-07-02 GB GBGB0414894.6A patent/GB0414894D0/en not_active Ceased
-
2005
- 2005-07-01 EP EP05756942A patent/EP1763674A2/en not_active Withdrawn
- 2005-07-01 US US11/630,769 patent/US20080076140A1/en not_active Abandoned
- 2005-07-01 WO PCT/GB2005/002592 patent/WO2006003414A2/en not_active Ceased
- 2005-07-01 AU AU2005258926A patent/AU2005258926A1/en not_active Abandoned
- 2005-07-01 BR BRPI0512948-6A patent/BRPI0512948A/pt not_active Application Discontinuation
- 2005-07-01 JP JP2007518700A patent/JP2008504551A/ja not_active Withdrawn
- 2005-07-01 CN CNA2005800225150A patent/CN101010589A/zh active Pending
- 2005-07-01 CA CA002571692A patent/CA2571692A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005258926A1 (en) | 2006-01-12 |
| CA2571692A1 (en) | 2006-01-12 |
| WO2006003414A3 (en) | 2006-03-16 |
| US20080076140A1 (en) | 2008-03-27 |
| WO2006003414A2 (en) | 2006-01-12 |
| JP2008504551A (ja) | 2008-02-14 |
| EP1763674A2 (en) | 2007-03-21 |
| GB0414894D0 (en) | 2004-08-04 |
| CN101010589A (zh) | 2007-08-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired |