BRPI0512986A - novos derivados de hidantoìna - Google Patents

novos derivados de hidantoìna

Info

Publication number
BRPI0512986A
BRPI0512986A BRPI0512986-9A BRPI0512986A BRPI0512986A BR PI0512986 A BRPI0512986 A BR PI0512986A BR PI0512986 A BRPI0512986 A BR PI0512986A BR PI0512986 A BRPI0512986 A BR PI0512986A
Authority
BR
Brazil
Prior art keywords
hydantoin derivatives
new hydantoin
new
preparation
pharmaceutical compositions
Prior art date
Application number
BRPI0512986-9A
Other languages
English (en)
Inventor
Balint Gabos
Lena Ripa
Kristina Stenvall
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BRPI0512986A publication Critical patent/BRPI0512986A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

NOVOS DERIVADOS DE HIDANTOìNA A invenção provê compostos de fórmula (I), onde R~ 1~ e R~ 2~ são como definidos no relatório descritivo; a processos para sua preparação; a composições farmacêuticas os contendo; a um processo para a preparação de composições farmacêuticas; e a seu uso em terapia.
BRPI0512986-9A 2004-07-05 2005-07-04 novos derivados de hidantoìna BRPI0512986A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0401763A SE0401763D0 (sv) 2004-07-05 2004-07-05 Compounds
PCT/SE2005/001093 WO2006004533A1 (en) 2004-07-05 2005-07-04 Compounds

Publications (1)

Publication Number Publication Date
BRPI0512986A true BRPI0512986A (pt) 2008-04-22

Family

ID=32768774

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0512986-9A BRPI0512986A (pt) 2004-07-05 2005-07-04 novos derivados de hidantoìna

Country Status (18)

Country Link
US (1) US20080004317A1 (pt)
EP (1) EP1794147A1 (pt)
JP (1) JP2008505172A (pt)
KR (1) KR20070038498A (pt)
CN (1) CN1980915A (pt)
AR (1) AR049577A1 (pt)
AU (1) AU2005260143B2 (pt)
BR (1) BRPI0512986A (pt)
CA (1) CA2569727A1 (pt)
IL (1) IL179907A0 (pt)
MX (1) MXPA06014663A (pt)
NO (1) NO20070570L (pt)
SA (1) SA05260190B1 (pt)
SE (1) SE0401763D0 (pt)
TW (1) TW200605888A (pt)
UY (1) UY29003A1 (pt)
WO (1) WO2006004533A1 (pt)
ZA (1) ZA200610701B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0100903D0 (sv) * 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
SE0100902D0 (sv) 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
SE0202539D0 (sv) 2002-08-27 2002-08-27 Astrazeneca Ab Compounds
US7648992B2 (en) * 2004-07-05 2010-01-19 Astrazeneca Ab Hydantoin derivatives for the treatment of obstructive airway diseases
SE0401762D0 (sv) * 2004-07-05 2004-07-05 Astrazeneca Ab Novel compounds
SE0403086D0 (sv) 2004-12-17 2004-12-17 Astrazeneca Ab Compounds
SE0403085D0 (sv) * 2004-12-17 2004-12-17 Astrazeneca Ab Novel componds
US7945626B2 (en) * 2005-03-16 2011-05-17 M&Fc Holding, Llc Method, system, apparatus, and computer program product for determining a physical location of a sensor
TW200740769A (en) 2006-03-16 2007-11-01 Astrazeneca Ab Novel process
TW200831488A (en) * 2006-11-29 2008-08-01 Astrazeneca Ab Novel compounds
WO2009007747A2 (en) * 2007-07-11 2009-01-15 Astrazeneca Ab Hydantoin derivatives used as mmp12 inhibitors
WO2010090680A1 (en) 2008-12-15 2010-08-12 Wyeth Llc Substituted oxindole cb2 agonists
MX376130B (es) * 2015-07-09 2025-03-07 Mitsubishi Tanabe Pharma Corp Derivados novedosos de imida y su uso como medicamento.
IT201700026858A1 (it) * 2017-03-10 2018-09-10 Univ Degli Studi Padova Uso di inibitori delle serin proteasi, in particolare di serpinb3

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0102935A3 (en) * 1998-06-03 2002-01-28 Gpi Nil Holdings Inc Wilmingto N-linked sulfonamides of n-heterocyclic carboxylic acids or carboxylic acid isosteres and pharmaceutical compositions containing them
WO1999065867A1 (en) * 1998-06-17 1999-12-23 Du Pont Pharmaceuticals Company Cyclic hydroxamic acids as metalloproteinase inhibitors
US6340691B1 (en) * 1999-01-27 2002-01-22 American Cyanamid Company Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase and tace inhibitors
EP1078923B1 (en) * 1999-08-02 2006-03-08 F. Hoffmann-La Roche Ag Process for the preparation of benzothiophene derivatives
US20020091107A1 (en) * 2000-09-08 2002-07-11 Madar David J. Oxazolidinone antibacterial agents
MXPA03008180A (es) * 2001-03-15 2003-12-12 Astrazeneca Ab Inhibidores de metaloproteinasa.
SE0100903D0 (sv) * 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
SE0100902D0 (sv) * 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
ATE445400T1 (de) * 2001-05-25 2009-10-15 Bristol Myers Squibb Co Hydantion-derivate als hemmer von matrix- metalloproteinasen
GB0114004D0 (en) * 2001-06-08 2001-08-01 Glaxo Group Ltd Chemical compounds
SE0103710D0 (sv) * 2001-11-07 2001-11-07 Astrazeneca Ab Compounds
SE0202539D0 (sv) * 2002-08-27 2002-08-27 Astrazeneca Ab Compounds
SE0202693D0 (sv) * 2002-09-11 2002-09-11 Astrazeneca Ab Compounds
GB0221246D0 (en) * 2002-09-13 2002-10-23 Astrazeneca Ab Compounds
GB0221250D0 (en) * 2002-09-13 2002-10-23 Astrazeneca Ab Compounds
TWI220073B (en) * 2003-07-24 2004-08-01 Au Optronics Corp Method for manufacturing polysilicon film
SE0401762D0 (sv) * 2004-07-05 2004-07-05 Astrazeneca Ab Novel compounds

Also Published As

Publication number Publication date
KR20070038498A (ko) 2007-04-10
AR049577A1 (es) 2006-08-16
IL179907A0 (en) 2007-05-15
ZA200610701B (en) 2008-08-27
WO2006004533A1 (en) 2006-01-12
US20080004317A1 (en) 2008-01-03
SA05260190B1 (ar) 2008-03-26
CA2569727A1 (en) 2006-01-12
UY29003A1 (es) 2006-02-24
MXPA06014663A (es) 2007-02-12
SE0401763D0 (sv) 2004-07-05
AU2005260143A1 (en) 2006-01-12
TW200605888A (en) 2006-02-16
JP2008505172A (ja) 2008-02-21
NO20070570L (no) 2007-04-10
EP1794147A1 (en) 2007-06-13
AU2005260143B2 (en) 2009-01-29
CN1980915A (zh) 2007-06-13

Similar Documents

Publication Publication Date Title
BR0108678A (pt) Novos compostos
BRPI0512974A (pt) novos derivados de hidantoìna para o tratamento de doenças obstrutivas das vias aéreas
BRPI0413094A (pt) derivados de quinolina e seu uso em terapia
BR112012032234A2 (pt) "derivados de heteroaril imidazolona como inibidores de jak".
BRPI0408347B8 (pt) derivados de pirimidina, seu uso, e composição e combinação farmacêuticas
NO20090628L (no) Pyridizinon derivativater
BR0111667A (pt) Novos compostos
BRPI0410563B8 (pt) compostos de pirazol-quinazolina, seus processos de preparação e composições farmacêuticas
BR0208338A (pt) Derivados de piridina
BR0307351A (pt) Composto, composição farmacêutica, método para tratar uma condição ou estado de doença mediados pela atividade de p38 quinase ou mediados por citocinas produzidas pela atividade de p38 quinase, uso de um composto, e, processo para preparar um composto
BR0206433A (pt) Composto, composição farmacêutica, processo para a prepapação de um composto, e, uso de um composto
SE0200920D0 (sv) Novel compounds
SE0301700D0 (sv) Novel compounds
BRPI0407734A (pt) derivados de adamantano, processo para sua preparação e composições farmacêuticas os contendo
BR0313041A (pt) Compostos; composições farmacêuticas; método para o tratamento e/ou profilaxia de doenças que estão associadas à modulação dos receptores de cb1; e uso de compostos
BRPI0607455A2 (pt) composto, processo para a preparação do mesmo, uso de um composto, e composição farmacêutica
EA201000436A1 (ru) Стероидные [3,2-с]пиразольные соединения, обладающие глюкокортикоидной активностью
BRPI0514750A (pt) derivados amida de 7-amino-3-fenil-diidropirimido[4, 5-d]pirimidinonas, sua fabricação e uso como inibidores de proteìna cinase
EA200700096A1 (ru) Производные 2-карбамид-4-фенилтиазола, способ их получения и их применение в терапии
BR0314379A (pt) Quinazolinonas espirocondensadas e a sua utilização como inibidores de fosfodiesterase
NO20070570L (no) Forbindelser.
BR0307461A (pt) Derivados de quinazolinona e seu uso como agonistas de cb
BRPI0606964A2 (pt) pirrolidinas e piperidinas derivadas do acetileno para uso como antagonistas de mglur5
BRPI0517035A (pt) novos compostos
UY29370A1 (es) Derivados de tiazol, composiciones que lo contienen, procedimientos de preparación y aplicaciones

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.