BRPI0512991A - uso de uma progestina, kit farmaceuticamente útil adaptado para a administração oral diária, e, método de contracepção em uma fêmea em idade de parto - Google Patents
uso de uma progestina, kit farmaceuticamente útil adaptado para a administração oral diária, e, método de contracepção em uma fêmea em idade de partoInfo
- Publication number
- BRPI0512991A BRPI0512991A BRPI0512991-5A BRPI0512991A BRPI0512991A BR PI0512991 A BRPI0512991 A BR PI0512991A BR PI0512991 A BRPI0512991 A BR PI0512991A BR PI0512991 A BRPI0512991 A BR PI0512991A
- Authority
- BR
- Brazil
- Prior art keywords
- contraception
- female
- pharmaceutically useful
- progestin
- oral administration
- Prior art date
Links
- 239000000583 progesterone congener Substances 0.000 title abstract 3
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical class C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 title abstract 2
- 230000035606 childbirth Effects 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000000262 estrogen Substances 0.000 abstract 1
- 229940011871 estrogen Drugs 0.000 abstract 1
- -1 steroid compound Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5355—Non-condensed oxazines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
USO DE UMA PROGESTINA, KIT FARMACEUTICAMENTE úTIL ADAPTADO PARA A ADMINISTRAçãO ORAL DIARIA, E, MéTODO DE CONTRACEPçãO EM UMA FêMEA EM IDADE DE PARTO Um método de contracepção é fornecido que envolve a ministração em 21 a 27 dias consecutivos de uma progestina na ausência de um estrogênio ou outro composto esteróide, seguido por 1 a 7 dias sem uma quantidade eficaz de um agente ativo. Também é descrito um kit farmaceuticamente útil para facilitar a ministração deste regime.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58604504P | 2004-07-07 | 2004-07-07 | |
| PCT/US2005/023955 WO2006014476A1 (en) | 2004-07-07 | 2005-07-06 | Cyclic progestin regimens and kits |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0512991A true BRPI0512991A (pt) | 2008-04-22 |
Family
ID=35064935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0512991-5A BRPI0512991A (pt) | 2004-07-07 | 2005-07-06 | uso de uma progestina, kit farmaceuticamente útil adaptado para a administração oral diária, e, método de contracepção em uma fêmea em idade de parto |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20060009428A1 (pt) |
| EP (1) | EP1773344A1 (pt) |
| JP (2) | JP5288796B2 (pt) |
| CN (2) | CN104208067A (pt) |
| AR (1) | AR049707A1 (pt) |
| AU (1) | AU2005269938A1 (pt) |
| BR (1) | BRPI0512991A (pt) |
| CA (1) | CA2571377C (pt) |
| MX (1) | MXPA06014579A (pt) |
| PA (1) | PA8638601A1 (pt) |
| PE (1) | PE20060378A1 (pt) |
| SV (1) | SV2006002165A (pt) |
| TW (1) | TW200603813A (pt) |
| WO (1) | WO2006014476A1 (pt) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6509334B1 (en) * | 1999-05-04 | 2003-01-21 | American Home Products Corporation | Cyclocarbamate derivatives as progesterone receptor modulators |
| US6391907B1 (en) * | 1999-05-04 | 2002-05-21 | American Home Products Corporation | Indoline derivatives |
| UA73119C2 (en) * | 2000-04-19 | 2005-06-15 | American Home Products Corpoir | Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors |
| CN104208067A (zh) | 2004-07-07 | 2014-12-17 | 惠氏公司 | 周期性黄体酮方案及试剂盒 |
| GT200500185A (es) * | 2004-08-09 | 2006-04-10 | Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos | |
| US20060246128A1 (en) * | 2005-04-28 | 2006-11-02 | Wyeth | Micronized tanaproget and compositions containing same |
| AR056328A1 (es) * | 2005-04-28 | 2007-10-03 | Wyeth Corp | TANAPROGET MICRONIZADO, COMPOSICIONES Y MÉTODOS PARA SU PREPARACIoN |
| DE602006007453D1 (de) * | 2005-04-28 | 2009-08-06 | Wyeth Corp | Zusammensetzungen mit mikronisiertem tanaproget |
| CN103989687A (zh) * | 2005-06-09 | 2014-08-20 | 惠氏公司 | 含有炔雌醇的tanaproget组合物 |
| US10137135B2 (en) | 2005-08-15 | 2018-11-27 | Allergan Sales, Llc | Formulations and methods for providing progestin-only contraception while minimizing adverse side effects associated therewith |
| US20070093548A1 (en) * | 2005-10-25 | 2007-04-26 | Wyeth | Use of progesterone receptor modulators |
| DE102006050558B4 (de) | 2006-10-26 | 2009-03-26 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System enthaltend Norelgestromin zur Kontrazeption und Hormonsubstitution |
| EA201070715A1 (ru) | 2007-12-20 | 2011-02-28 | Тева Вимен'С Хелс, Инк. | Режимы дозирования, фармацевтические композиции и упаковки для экстренной контрацепции |
| DE102008022221A1 (de) * | 2008-05-06 | 2009-11-12 | Universität des Saarlandes | Inhibitoren der humanen Aldosteronsynthase CYP11B2 |
| CA2740002C (en) | 2008-10-08 | 2016-11-01 | Agile Therapeutics, Inc. | Transdermal delivery |
| EP2343964A4 (en) | 2008-10-08 | 2012-11-07 | Agile Therapeutics Inc | TRANSDERMAL ADMINISTRATION |
| CA2740005C (en) | 2008-10-08 | 2016-11-01 | Agile Therapeutics, Inc. | Transdermal delivery |
| WO2010111488A1 (en) | 2009-03-27 | 2010-09-30 | Agile Therapeutics, Inc. | Transdermal delivery |
| CN102811730B (zh) * | 2010-02-08 | 2014-07-09 | 杜涛 | 孕激素作为糖皮质激素增敏剂的使用 |
| AR081670A1 (es) | 2010-06-29 | 2012-10-10 | Leon Farma Sa Lab | Composicion farmaceutica que comprende drospirenona y kit anticonceptivo |
| US10849857B2 (en) | 2010-07-28 | 2020-12-01 | Laboratorios Leon Farma Sa | Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same |
| US11351122B1 (en) | 2010-07-28 | 2022-06-07 | Laboratorios Leon Farma Sa | Synthetic progestogens and pharmaceutical compositions comprising the same |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| ES2885523T3 (es) | 2011-11-23 | 2021-12-14 | Therapeuticsmd Inc | Formulaciones y terapias de reposición hormonal de combinación naturales |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| EP2730284A1 (en) * | 2012-11-12 | 2014-05-14 | Naari AG | Levonorgestrel-only-composition for optimized oral contraception with defined levonorgestrel content, dosage regimen and pharmaceutical preparation |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| MX2016014281A (es) | 2014-05-22 | 2017-02-22 | Therapeuticsmd Inc | Formulaciones y terapias de reemplazo de combinación de hormonas naturales. |
| HUE065350T2 (hu) * | 2015-06-23 | 2024-05-28 | Laboratorios Leon Farma Sa | Drospirenonalapú fogamzásgátló túlsúllyal érintett nõi beteg számára |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| AU2017239645A1 (en) | 2016-04-01 | 2018-10-18 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| CN107982520A (zh) * | 2017-12-25 | 2018-05-04 | 上海交通大学医学院附属第九人民医院 | 外源性MPA与hMG在制备动物模型药物中的应用 |
| US11679114B2 (en) | 2021-07-26 | 2023-06-20 | Navad Life Sciences Pte | Progestogen-only oral contraception |
| WO2024218800A1 (en) * | 2023-04-21 | 2024-10-24 | Akums Drugs And Pharmaceuticals Limited | Vaginal drug delivery system of dydrogesterone |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU581486B2 (en) * | 1985-12-30 | 1989-02-23 | Warner-Lambert Company | Graduated estrogen contraceptive |
| EP0559240B1 (en) * | 1987-09-24 | 2001-12-05 | Jencap Research Limited | Contraceptive packages containing oestrogen and progestin |
| WO1998004269A1 (en) | 1996-07-26 | 1998-02-05 | American Home Products Corporation | Monophasic contraceptive method and kit comprising a combination of a progestin and estrogen |
| WO2001030355A1 (fr) * | 1999-10-25 | 2001-05-03 | Laboratoire Theramex | Medicament contraceptif a base d'un progestatif et d'un estrogene et son mode de preparation |
| WO1999051214A2 (en) * | 1998-04-07 | 1999-10-14 | Akzo Nobel N.V. | Progestogen-only contraceptive kit |
| MXPA01011287A (es) * | 1999-05-04 | 2003-07-14 | American Home Prod | Derivados de ciclotiocarbamato como moduladores de receptor de progesterona. |
| US6444668B1 (en) * | 1999-05-04 | 2002-09-03 | Wyeth | Combination regimens using progesterone receptor modulators |
| US6509334B1 (en) * | 1999-05-04 | 2003-01-21 | American Home Products Corporation | Cyclocarbamate derivatives as progesterone receptor modulators |
| US6407101B1 (en) * | 1999-05-04 | 2002-06-18 | American Home Products Corporation | Cyanopyrroles |
| EP1605949A2 (en) * | 1999-08-31 | 2005-12-21 | Schering Aktiengesellschaft | Mesoprogestins (progesterone receptor modulators) as a component of female contraceptives |
| UA73119C2 (en) * | 2000-04-19 | 2005-06-15 | American Home Products Corpoir | Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors |
| AR040644A1 (es) * | 2002-06-25 | 2005-04-13 | Wyeth Corp | Un moduladores del receptor de progesterona benzoxazina-2-tiona, una composicion farmaceutica, uso del compuesto para preparar un dedicamento para tratar una enfermedad neoplasica-hormona-dependiente y el uso de un compuesto benzoxazina-2-tiona, benzoxazina-2-ilideno cianamida o benzoxazina-2-iliden |
| CN104208067A (zh) | 2004-07-07 | 2014-12-17 | 惠氏公司 | 周期性黄体酮方案及试剂盒 |
| GT200500186A (es) | 2004-07-07 | 2006-03-02 | Regimenes anticonceptivos con antagonistas del receptor de progesterona y kits | |
| GT200500185A (es) | 2004-08-09 | 2006-04-10 | Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos | |
| GT200500183A (es) | 2004-08-09 | 2006-04-10 | Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos |
-
2005
- 2005-07-06 CN CN201410381416.2A patent/CN104208067A/zh active Pending
- 2005-07-06 SV SV2005002165A patent/SV2006002165A/es not_active Application Discontinuation
- 2005-07-06 CN CNA2005800227796A patent/CN1980676A/zh active Pending
- 2005-07-06 PA PA20058638601A patent/PA8638601A1/es unknown
- 2005-07-06 AU AU2005269938A patent/AU2005269938A1/en not_active Abandoned
- 2005-07-06 AR ARP050102805A patent/AR049707A1/es unknown
- 2005-07-06 JP JP2007520464A patent/JP5288796B2/ja not_active Expired - Fee Related
- 2005-07-06 BR BRPI0512991-5A patent/BRPI0512991A/pt not_active IP Right Cessation
- 2005-07-06 MX MXPA06014579A patent/MXPA06014579A/es active IP Right Grant
- 2005-07-06 US US11/174,592 patent/US20060009428A1/en not_active Abandoned
- 2005-07-06 PE PE2005000783A patent/PE20060378A1/es not_active Application Discontinuation
- 2005-07-06 EP EP05768415A patent/EP1773344A1/en not_active Ceased
- 2005-07-06 TW TW094122827A patent/TW200603813A/zh unknown
- 2005-07-06 WO PCT/US2005/023955 patent/WO2006014476A1/en not_active Ceased
- 2005-07-06 CA CA2571377A patent/CA2571377C/en not_active Expired - Fee Related
-
2010
- 2010-05-03 US US12/772,280 patent/US8604027B2/en not_active Expired - Fee Related
-
2012
- 2012-09-27 JP JP2012214378A patent/JP2013040181A/ja active Pending
-
2013
- 2013-11-08 US US14/074,946 patent/US20140094458A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20140094458A1 (en) | 2014-04-03 |
| WO2006014476A1 (en) | 2006-02-09 |
| JP2008505909A (ja) | 2008-02-28 |
| US8604027B2 (en) | 2013-12-10 |
| CA2571377A1 (en) | 2006-02-09 |
| CN104208067A (zh) | 2014-12-17 |
| PE20060378A1 (es) | 2006-06-02 |
| EP1773344A1 (en) | 2007-04-18 |
| JP5288796B2 (ja) | 2013-09-11 |
| AU2005269938A1 (en) | 2006-02-09 |
| US20100292198A1 (en) | 2010-11-18 |
| JP2013040181A (ja) | 2013-02-28 |
| PA8638601A1 (es) | 2006-07-03 |
| MXPA06014579A (es) | 2007-03-01 |
| AR049707A1 (es) | 2006-08-30 |
| SV2006002165A (es) | 2006-05-09 |
| CA2571377C (en) | 2014-03-25 |
| CN1980676A (zh) | 2007-06-13 |
| US20060009428A1 (en) | 2006-01-12 |
| TW200603813A (en) | 2006-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25D | Requested change of name of applicant approved |
Owner name: WYETH LLC. (US) |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 11A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2385 DE 20-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |