BRPI0513903A - derivados de cetolìdeos úteis como agentes antimicrobianos, seus processos de preparação e composições farmacêuticas compreendendo os mesmos - Google Patents

derivados de cetolìdeos úteis como agentes antimicrobianos, seus processos de preparação e composições farmacêuticas compreendendo os mesmos

Info

Publication number
BRPI0513903A
BRPI0513903A BRPI0513903-1A BRPI0513903A BRPI0513903A BR PI0513903 A BRPI0513903 A BR PI0513903A BR PI0513903 A BRPI0513903 A BR PI0513903A BR PI0513903 A BRPI0513903 A BR PI0513903A
Authority
BR
Brazil
Prior art keywords
pharmaceutical compositions
ketolide derivatives
same
preparation processes
antimicrobial agents
Prior art date
Application number
BRPI0513903-1A
Other languages
English (en)
Inventor
Biswajit Das
Mohammad Salman
Atul Kashinath Hajare
Ramadass Venkataramanan
Rita Katoch
Rajesh Kumar
Gobind Singh Kapkoti
Anjan Chakrabarti
Anish Bandyopadhyay
Santosh Haribhau Kurhade
Yogesh Baban Surase
Ashok Rattan
Original Assignee
Ranbaxy Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd
Publication of BRPI0513903A publication Critical patent/BRPI0513903A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

DERIVADOS DE CETOLìDEOS úTEIS COMO AGENTES ANTIMICROBIANOS, SEUS PROCESSOS DE PREPARAçãO E COMPOSIçõES FARMACêUTICAS COMPREENDENDO OS MESMOS. A presente invenção refere-se a derivados de cetolídeos, os quais podem ser usados como agentes bacterianos. Particularmente, os compostos aqui descritos podem ser usados no tratamento ou na prevenção de condições causadas ou influenciadas por bactérias Gram-positivas, Gram-negativas ou anaeróbicas, mais particularmente contra, por exemplo, Staphylococci, Streptococci, Enterococci, Haemophilus, Moraxalla spp., Chlamydia spp., Mycoplasm, Legionella spp., Mycobacterium, Helicobacter, Clostridium, Bacteroides, Corynebacterium, Bacillus ou Enterobactericeae. A presente invenção refere-se ainda a processos preparação dos referidos derivados de cetolídeos, composições farmacêuticas dos mesmos e a métodos tratamento de infecções bacterianas.
BRPI0513903-1A 2004-07-28 2005-07-28 derivados de cetolìdeos úteis como agentes antimicrobianos, seus processos de preparação e composições farmacêuticas compreendendo os mesmos BRPI0513903A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN1400DE2004 2004-07-28
IN1388DE2005 2005-05-30
PCT/US2005/027875 WO2006080954A1 (en) 2004-07-28 2005-07-28 Ketolide derivatives as antibacterial agents

Publications (1)

Publication Number Publication Date
BRPI0513903A true BRPI0513903A (pt) 2008-05-20

Family

ID=36480874

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0513903-1A BRPI0513903A (pt) 2004-07-28 2005-07-28 derivados de cetolìdeos úteis como agentes antimicrobianos, seus processos de preparação e composições farmacêuticas compreendendo os mesmos

Country Status (6)

Country Link
US (1) US20080287376A1 (pt)
EP (1) EP1794171A2 (pt)
JP (1) JP2008508322A (pt)
BR (1) BRPI0513903A (pt)
RU (1) RU2397987C2 (pt)
WO (1) WO2006080954A1 (pt)

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UA85937C2 (uk) 2004-12-21 2009-03-10 Пфайзер Продактс Інк. Макроліди
US20090075916A1 (en) 2005-11-23 2009-03-19 Upadhyay Dilip J Use of Macrolide Derivatives for Treating Acne
WO2007060618A2 (en) * 2005-11-23 2007-05-31 Ranbaxy Laboratories Limited Macrolides derivatives as antibacterial agents
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EP2214484A4 (en) 2007-10-25 2013-01-02 Cempra Pharmaceuticals Inc PROCESS FOR PREPARING ANTIBACTERIAL MAKROLIDE AGENTS
JP5711135B2 (ja) 2008-10-24 2015-04-30 センプラ ファーマシューティカルズ，インコーポレイテッド 胃腸疾患を治療するための方法
WO2010096051A1 (en) * 2009-02-18 2010-08-26 Enanta Pharmaceuticals, Inc. 6,11-bicyclolides: bridged biaryl amide macrolide derivatives
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
ES2608285T3 (es) 2009-09-10 2017-04-07 Cempra Pharmaceuticals, Inc. Procedimientos para el tratamiento de paludismo, tuberculosis y enfermedades por MAC
MX361413B (es) 2010-03-22 2018-12-05 Cempra Pharmaceuticals Inc Star Formas cristalinas de un macrólido y usos para las mismas.
CN102917708B (zh) 2010-05-20 2015-11-25 森普拉制药公司 制备大环内酯和酮内酯及其中间体的方法
EP2613630A4 (en) * 2010-09-10 2014-01-15 Cempra Pharmaceuticals Inc HYDROGEN BOND FOR THE PREPARATION OF FLUOROCHETOLIDES FOR THE TREATMENT OF DISEASES
PT2673285T (pt) * 2010-12-09 2017-10-19 Wockhardt Ltd Resumo
NZ700182A (en) 2012-03-27 2017-02-24 Cempra Pharmaceuticals Inc Parenteral formulations for administering macrolide antibiotics
AU2014239959A1 (en) 2013-03-14 2015-10-01 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
CN105188712A (zh) 2013-03-15 2015-12-23 森普拉制药公司 用于制备大环内酯抗菌剂的收敛方法
JP6437523B2 (ja) 2013-04-04 2018-12-12 プレジデント アンド フェローズ オブ ハーバード カレッジ マクロライドならびにそれらの調製および使用の方法
CN105524132B (zh) * 2014-09-30 2019-07-02 中国医学科学院药物研究所 含有喹啉取代基的红霉素a酮内酯类抗生素衍生物、其制备方法及应用
CN106998685A (zh) * 2014-10-08 2017-08-01 哈佛大学的校长及成员们 14‑元酮内酯及其制备和使用方法
EP3273969A4 (en) 2015-03-25 2018-11-21 President and Fellows of Harvard College Macrolides with modified desosamine sugars and uses thereof
CN106518939B (zh) * 2015-09-14 2019-12-31 江苏奥赛康药业有限公司 一种制备Solithromycin化合物的方法
CN107129514B (zh) * 2016-03-02 2019-12-13 中国医学科学院药物研究所 红霉素a酮内酯类抗生素衍生物、其制备方法及应用

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FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
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CA2523134A1 (en) * 2003-04-25 2004-11-11 Chiron Corporation Pyridyl substituted ketolide antibiotics
US7271155B2 (en) * 2005-01-07 2007-09-18 Enanta Pharmaceuticals, Inc. 9A, 11-2C-bicyclic 9a-azalide derivatives

Also Published As

Publication number Publication date
RU2007107340A (ru) 2008-09-10
RU2397987C2 (ru) 2010-08-27
US20080287376A1 (en) 2008-11-20
JP2008508322A (ja) 2008-03-21
EP1794171A2 (en) 2007-06-13
WO2006080954A1 (en) 2006-08-03

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2260 DE 29/04/2014.