BRPI0513938A - composição farmacêutica contendo drospirenona e etinilestradiol - Google Patents
composição farmacêutica contendo drospirenona e etinilestradiolInfo
- Publication number
- BRPI0513938A BRPI0513938A BRPI0513938-4A BRPI0513938A BRPI0513938A BR PI0513938 A BRPI0513938 A BR PI0513938A BR PI0513938 A BRPI0513938 A BR PI0513938A BR PI0513938 A BRPI0513938 A BR PI0513938A
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical composition
- composition containing
- ethinyl estradiol
- containing drospirenone
- ethinylestradiol
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 5
- 229940007690 drospirenone and ethinylestradiol Drugs 0.000 title abstract 3
- 238000004090 dissolution Methods 0.000 abstract 2
- BFPYWIDHMRZLRN-UHFFFAOYSA-N 17alpha-ethynyl estradiol Natural products OC1=CC=C2C3CCC(C)(C(CC4)(O)C#C)C4C3CCC2=C1 BFPYWIDHMRZLRN-UHFFFAOYSA-N 0.000 abstract 1
- BFPYWIDHMRZLRN-SLHNCBLASA-N Ethinyl estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 BFPYWIDHMRZLRN-SLHNCBLASA-N 0.000 abstract 1
- 230000002513 anti-ovulatory effect Effects 0.000 abstract 1
- 229960002568 ethinylestradiol Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reproductive Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
COMPOSIçãO FARMACêUTICA CONTENDO DROSPIRENONA E ETINILESTRADIOL Trata-se a presente invenção de uma composição farmacêutica contendo Drospirenona e Etinilestradiol, com uma taxa de dissolução melhorada, bem como de um método de preparação de uma formulação farmacêutica contendo Drospirenona e Etinilestradiol, para que seu perfil de dissolução seja melhorado. A dita formulação farmacêutica pode ser utilizada para produzir um efeito anovulatório, quando administrada corretamente, em seres humanos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04103837A EP1625849A1 (en) | 2004-08-09 | 2004-08-09 | Pharmaceutical composition comprising drospirenone and ethynylestradiol |
| PCT/EP2005/053759 WO2006015956A1 (en) | 2004-08-09 | 2005-08-02 | Pharmaceutical composition comprising drospirenone and ethynylestradiol |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0513938A true BRPI0513938A (pt) | 2008-05-20 |
| BRPI0513938B1 BRPI0513938B1 (pt) | 2018-09-25 |
| BRPI0513938B8 BRPI0513938B8 (pt) | 2021-05-25 |
Family
ID=34929434
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0513938A BRPI0513938B8 (pt) | 2004-08-09 | 2005-08-02 | composição farmacêutica contendo drospirenona e etinilestradiol |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20090227546A1 (pt) |
| EP (2) | EP1625849A1 (pt) |
| JP (1) | JP2008509195A (pt) |
| KR (1) | KR20070045247A (pt) |
| CN (1) | CN101022811B (pt) |
| AR (1) | AR045576A1 (pt) |
| AT (1) | ATE464053T1 (pt) |
| AU (1) | AU2005271206B2 (pt) |
| BR (1) | BRPI0513938B8 (pt) |
| CA (1) | CA2574997A1 (pt) |
| DE (1) | DE602005020694D1 (pt) |
| ES (1) | ES2344356T3 (pt) |
| IL (1) | IL180899A0 (pt) |
| MA (1) | MA28844B1 (pt) |
| NO (1) | NO20071297L (pt) |
| RU (1) | RU2007108666A (pt) |
| UA (1) | UA87513C2 (pt) |
| WO (1) | WO2006015956A1 (pt) |
| ZA (1) | ZA200702038B (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5649305B2 (ja) * | 2006-12-20 | 2015-01-07 | テバ ウィメンズ ヘルス インコーポレイテッド | プロゲスチンを含む口腔内崩壊性固体剤形ならびにその製造方法および使用方法 |
| HUP0700826A3 (en) * | 2007-12-20 | 2010-03-29 | Richter Gedeon Nyrt | Coated tablet containing drospirenone and process for producing the same |
| DE102008037025C5 (de) | 2008-08-08 | 2016-07-07 | Jesalis Pharma Gmbh | Verfahren zur Herstellung kristalliner Wirkstoff-Mikropartikel bzw. einer Wirkstoffpartikel-Festkörperform |
| US20100256194A1 (en) * | 2009-04-01 | 2010-10-07 | Bial - Portela & Ca, S.A. | Pharmaceutical formulations comprising nitrocatechol derivatives and methods of making the same |
| ES2730678T3 (es) | 2009-04-01 | 2019-11-12 | Bial Portela & Ca Sa | Formulaciones farmacéuticas que comprenden derivados de nitrocatecol y métodos para fabricarlas |
| US10849857B2 (en) * | 2010-07-28 | 2020-12-01 | Laboratorios Leon Farma Sa | Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same |
| US11351122B1 (en) | 2010-07-28 | 2022-06-07 | Laboratorios Leon Farma Sa | Synthetic progestogens and pharmaceutical compositions comprising the same |
| AR081670A1 (es) | 2010-06-29 | 2012-10-10 | Leon Farma Sa Lab | Composicion farmaceutica que comprende drospirenona y kit anticonceptivo |
| US9603860B2 (en) * | 2010-07-28 | 2017-03-28 | Laboratorios Leon Farma Sa | Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same |
| US20140045900A1 (en) | 2011-02-11 | 2014-02-13 | Bial-Portela & Ca, S.A. | Administration regime for nitrocatechols |
| CN102274235B (zh) * | 2011-06-27 | 2013-03-13 | 潍坊中狮制药有限公司 | 一种新的避孕药物组合及制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4727064A (en) * | 1984-04-25 | 1988-02-23 | The United States Of America As Represented By The Department Of Health And Human Services | Pharmaceutical preparations containing cyclodextrin derivatives |
| FR2722984B1 (fr) * | 1994-07-26 | 1996-10-18 | Effik Lab | Procede de preparation de formes pharmaceutiques seches et les compositions pharmaceutiques ainsi realisees |
| US6027747A (en) * | 1997-11-11 | 2000-02-22 | Terracol; Didier | Process for the production of dry pharmaceutical forms and the thus obtained pharmaceutical compositions |
| SK287634B6 (sk) * | 1999-08-31 | 2011-04-05 | Bayer Schering Pharma Aktiengesellschaft | Farmaceutická kompozícia obsahujúca drospirenón a etinylestradiol a farmaceutický prípravok |
| BR0014159A (pt) * | 1999-08-31 | 2002-05-07 | Schering Ag | Combinação farmacêutica de etinilestradiol e drospirenona para uso como um anticoncepcional |
| CA2431521E (en) * | 2000-12-14 | 2013-04-16 | Ortho-Mcneil Pharmaceutical, Inc. | Steroid hormone products and methods for preparing them |
| EP1216712A1 (en) * | 2000-12-20 | 2002-06-26 | Schering Aktiengesellschaft | Cyclodextrin-drospirenone inclusion complexes |
-
2004
- 2004-08-09 EP EP04103837A patent/EP1625849A1/en not_active Withdrawn
- 2004-09-03 AR ARP040103168A patent/AR045576A1/es not_active Application Discontinuation
-
2005
- 2005-08-02 US US11/573,499 patent/US20090227546A1/en not_active Abandoned
- 2005-08-02 EP EP05777862A patent/EP1848441B1/en not_active Revoked
- 2005-08-02 AT AT05777862T patent/ATE464053T1/de not_active IP Right Cessation
- 2005-08-02 ES ES05777862T patent/ES2344356T3/es not_active Expired - Lifetime
- 2005-08-02 RU RU2007108666/15A patent/RU2007108666A/ru not_active Application Discontinuation
- 2005-08-02 UA UAA200702482A patent/UA87513C2/ru unknown
- 2005-08-02 KR KR1020077003265A patent/KR20070045247A/ko not_active Withdrawn
- 2005-08-02 BR BRPI0513938A patent/BRPI0513938B8/pt active IP Right Grant
- 2005-08-02 DE DE602005020694T patent/DE602005020694D1/de not_active Expired - Lifetime
- 2005-08-02 ZA ZA200702038A patent/ZA200702038B/xx unknown
- 2005-08-02 CN CN2005800271055A patent/CN101022811B/zh not_active Expired - Fee Related
- 2005-08-02 AU AU2005271206A patent/AU2005271206B2/en not_active Ceased
- 2005-08-02 WO PCT/EP2005/053759 patent/WO2006015956A1/en not_active Ceased
- 2005-08-02 JP JP2007525283A patent/JP2008509195A/ja not_active Withdrawn
- 2005-08-02 CA CA002574997A patent/CA2574997A1/en not_active Abandoned
-
2007
- 2007-01-23 IL IL180899A patent/IL180899A0/en unknown
- 2007-03-02 MA MA29728A patent/MA28844B1/fr unknown
- 2007-03-09 NO NO20071297A patent/NO20071297L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HK1109579A1 (en) | 2008-06-13 |
| BRPI0513938B1 (pt) | 2018-09-25 |
| CA2574997A1 (en) | 2006-02-16 |
| ES2344356T3 (es) | 2010-08-25 |
| IL180899A0 (en) | 2007-07-04 |
| WO2006015956A1 (en) | 2006-02-16 |
| EP1848441A1 (en) | 2007-10-31 |
| JP2008509195A (ja) | 2008-03-27 |
| ATE464053T1 (de) | 2010-04-15 |
| KR20070045247A (ko) | 2007-05-02 |
| MA28844B1 (fr) | 2007-09-03 |
| ZA200702038B (en) | 2008-08-27 |
| NO20071297L (no) | 2007-05-02 |
| BRPI0513938B8 (pt) | 2021-05-25 |
| EP1848441B1 (en) | 2010-04-14 |
| AR045576A1 (es) | 2005-11-02 |
| RU2007108666A (ru) | 2008-09-20 |
| AU2005271206A1 (en) | 2006-02-16 |
| CN101022811A (zh) | 2007-08-22 |
| CN101022811B (zh) | 2010-09-15 |
| AU2005271206B2 (en) | 2009-11-26 |
| DE602005020694D1 (de) | 2010-05-27 |
| UA87513C2 (ru) | 2009-07-27 |
| EP1625849A1 (en) | 2006-02-15 |
| US20090227546A1 (en) | 2009-09-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
|
| B08G | Application fees: restoration [chapter 8.7 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: PAGAR RESTAURACAO. |
|
| B08G | Application fees: restoration [chapter 8.7 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 25/09/2018, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 02/08/2005 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |