BRPI0514020A - oxindóis oxazolidinonas como agentes antibacterianos - Google Patents

oxindóis oxazolidinonas como agentes antibacterianos

Info

Publication number
BRPI0514020A
BRPI0514020A BRPI0514020-0A BRPI0514020A BRPI0514020A BR PI0514020 A BRPI0514020 A BR PI0514020A BR PI0514020 A BRPI0514020 A BR PI0514020A BR PI0514020 A BRPI0514020 A BR PI0514020A
Authority
BR
Brazil
Prior art keywords
oxindoles
antibacterial agents
oxazolidinones
alkyl
oxazolidinone
Prior art date
Application number
BRPI0514020-0A
Other languages
English (en)
Inventor
Gary Wayne Luehr
Rama Jain
Adam Robert Renslo
Mikhail Fedorovich Gordeev
Vara Prasad Venkata Na Josyula
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35079333&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0514020(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Publication of BRPI0514020A publication Critical patent/BRPI0514020A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

OXINDóIS OXAZOLIDINONAS COMO AGENTES ANTIBACTERIANOS A presente invenção se refere a novos derivados oxazolidinonas de oxindóis de fórmula 1 ou um sal farmaceuticamente aceitável destes em que: Y¬ 1¬ é CH ou CE, R¬ 1¬ é alquila C~ 1~-~ 4»~, opcionalmente substituída por um átomo de flúor, ou R¬ 1¬ é cicloalquila C~ 3~-~ 5»~, e R¬ 2¬ é alquila C~ 1~-~ 2»~. Estes compostos são úteis como agentes antibacterianos.
BRPI0514020-0A 2004-08-06 2005-07-19 oxindóis oxazolidinonas como agentes antibacterianos BRPI0514020A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59982204P 2004-08-06 2004-08-06
PCT/IB2005/002196 WO2006016220A1 (en) 2004-08-06 2005-07-19 Oxindole oxazolidinones as antibacterial agents

Publications (1)

Publication Number Publication Date
BRPI0514020A true BRPI0514020A (pt) 2008-05-27

Family

ID=35079333

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0514020-0A BRPI0514020A (pt) 2004-08-06 2005-07-19 oxindóis oxazolidinonas como agentes antibacterianos
BRPI0513083-2A BRPI0513083A (pt) 2004-08-06 2005-07-19 oxazolidinonas contendo oxindóis como agentes antibacterianos

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI0513083-2A BRPI0513083A (pt) 2004-08-06 2005-07-19 oxazolidinonas contendo oxindóis como agentes antibacterianos

Country Status (24)

Country Link
US (2) US20080262056A1 (pt)
EP (2) EP1781642A1 (pt)
JP (2) JP2008509125A (pt)
CN (1) CN101001853A (pt)
AP (1) AP2007003904A0 (pt)
AR (1) AR050101A1 (pt)
AU (1) AU2005270951A1 (pt)
BR (2) BRPI0514020A (pt)
CA (2) CA2576041A1 (pt)
EA (1) EA200700322A1 (pt)
GT (1) GT200500204A (pt)
IL (1) IL180957A0 (pt)
MA (1) MA28793B1 (pt)
MX (2) MX2007001568A (pt)
NL (1) NL1029686C2 (pt)
NO (1) NO20071230L (pt)
PA (1) PA8640901A1 (pt)
PE (1) PE20060351A1 (pt)
SV (1) SV2006002180A (pt)
TN (1) TNSN07043A1 (pt)
TW (1) TWI289448B (pt)
UY (1) UY29048A1 (pt)
WO (2) WO2006016220A1 (pt)
ZA (1) ZA200700476B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1869029A1 (en) * 2005-04-06 2007-12-26 Pharmacia & Upjohn Company LLC An oxindole oxazolidinone as antibacterial agent
AU2006231919A1 (en) 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents
CN103483329B (zh) * 2013-09-07 2015-08-05 吉首大学 呋喃酮-芳基-噁唑烷酮型化合物及其制法和用途
CN103420995B (zh) * 2013-09-07 2015-07-01 吉首大学 噁唑烷酮-烷胺基-呋喃酮型化合物及其制法和用途
CN110963996B (zh) * 2017-10-25 2022-09-09 西南大学 含苯乙酮取代基的靛红唑醇类化合物及其制备方法和医药应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2865211B2 (ja) * 1988-09-15 1999-03-08 ファルマシア・アンド・アップジョン・カンパニー ５’―インドリニル―５β―アミドメチルオキサゾリジン―２―オン類、３―（縮合環置換）フェニル―５β―アミドメチルオキサゾリジン―２―オン類および３―（窒素原子置換）フェニル―５β―アミドメチルオキサゾリジン―２―オン類
US5164510A (en) * 1988-09-15 1992-11-17 The Upjohn Company 5'Indolinyl-5β-amidomethyloxazolidin-2-ones
DE4425612A1 (de) * 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
PT792273E (pt) * 1994-11-15 2003-06-30 Upjohn Co Produtos antibacterianos de oxazolidinona substituida com oxazina e tiazina biciclicas
HRP960159A2 (en) * 1995-04-21 1997-08-31 Bayer Ag Benzocyclopentane oxazolidinones containing heteroatoms
HUP9901979A3 (en) * 1995-09-01 2000-03-28 Upjohn Co Phenyloxazolidinones having a c-c bond to 4-8 membered heterocyclic rings and pharmaceutical compositions containing the same
DE19601265A1 (de) * 1996-01-16 1997-07-17 Bayer Ag 2-Oxo- und 2-Thio-1,2-dihydrochinolinyl-oxazolidinone
DE19601627A1 (de) * 1996-01-18 1997-07-24 Bayer Ag Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
DE69716925T2 (de) * 1996-08-21 2003-09-11 Pharmacia & Upjohn Co., Kalamazoo Isoxazoline derivate und ihre verwendung als antimikroben
GB9717804D0 (en) * 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
BR9907183A (pt) * 1998-01-23 2003-06-10 Versicor Inc Colet neas combinatórias de oxazolidinona, composições e processos de preparação
GB9812019D0 (en) * 1998-06-05 1998-07-29 Zeneca Ltd Chemical compounds
CN1142158C (zh) * 1999-02-01 2004-03-17 法玛西雅厄普约翰美国公司 制备环状含硫氟的噁唑烷酮的方法
JP2003501351A (ja) * 1999-05-27 2003-01-14 ファルマシア・アンド・アップジョン・カンパニー 抗菌剤としての二環系オキサゾリジノン
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
US7012088B2 (en) * 2003-02-24 2006-03-14 Pharmacia & Upjohn Company Indolone oxazolidinones and derivatives thereof
AU2006231919A1 (en) * 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents

Also Published As

Publication number Publication date
NL1029686A1 (nl) 2006-02-07
TWI289448B (en) 2007-11-11
NL1029686C2 (nl) 2006-07-18
TW200612924A (en) 2006-05-01
SV2006002180A (es) 2006-06-26
WO2006016220A1 (en) 2006-02-16
WO2006016221A1 (en) 2006-02-16
TNSN07043A1 (fr) 2008-06-02
MX2007001568A (es) 2007-04-16
AU2005270951A1 (en) 2006-02-16
AR050101A1 (es) 2006-09-27
CA2576041A1 (en) 2006-02-16
BRPI0513083A (pt) 2008-04-22
US20060030609A1 (en) 2006-02-09
JP2008509126A (ja) 2008-03-27
EP1781642A1 (en) 2007-05-09
MX2007001526A (es) 2007-03-27
US20080262056A1 (en) 2008-10-23
AP2007003904A0 (en) 2007-02-28
PA8640901A1 (es) 2007-01-17
EA200700322A1 (ru) 2007-08-31
GT200500204A (es) 2006-03-02
NO20071230L (no) 2007-05-04
ZA200700476B (en) 2008-10-29
EP1781643A1 (en) 2007-05-09
IL180957A0 (en) 2007-07-04
MA28793B1 (fr) 2007-08-01
CN101001853A (zh) 2007-07-18
JP2008509125A (ja) 2008-03-27
PE20060351A1 (es) 2006-05-03
UY29048A1 (es) 2006-03-31
CA2575702A1 (en) 2006-02-16

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.