BRPI0514020A - oxindóis oxazolidinonas como agentes antibacterianos - Google Patents

oxindóis oxazolidinonas como agentes antibacterianos

Info

Publication number
BRPI0514020A
BRPI0514020A BRPI0514020-0A BRPI0514020A BRPI0514020A BR PI0514020 A BRPI0514020 A BR PI0514020A BR PI0514020 A BRPI0514020 A BR PI0514020A BR PI0514020 A BRPI0514020 A BR PI0514020A
Authority
BR
Brazil
Prior art keywords
oxindoles
antibacterial agents
oxazolidinones
alkyl
oxazolidinone
Prior art date
Application number
BRPI0514020-0A
Other languages
English (en)
Inventor
Gary Wayne Luehr
Rama Jain
Adam Robert Renslo
Mikhail Fedorovich Gordeev
Vara Prasad Venkata Na Josyula
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35079333&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0514020(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Publication of BRPI0514020A publication Critical patent/BRPI0514020A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

OXINDóIS OXAZOLIDINONAS COMO AGENTES ANTIBACTERIANOS A presente invenção se refere a novos derivados oxazolidinonas de oxindóis de fórmula 1 ou um sal farmaceuticamente aceitável destes em que: Y¬ 1¬ é CH ou CE, R¬ 1¬ é alquila C~ 1~-~ 4»~, opcionalmente substituída por um átomo de flúor, ou R¬ 1¬ é cicloalquila C~ 3~-~ 5»~, e R¬ 2¬ é alquila C~ 1~-~ 2»~. Estes compostos são úteis como agentes antibacterianos.
BRPI0514020-0A 2004-08-06 2005-07-19 oxindóis oxazolidinonas como agentes antibacterianos BRPI0514020A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59982204P 2004-08-06 2004-08-06
PCT/IB2005/002196 WO2006016220A1 (en) 2004-08-06 2005-07-19 Oxindole oxazolidinones as antibacterial agents

Publications (1)

Publication Number Publication Date
BRPI0514020A true BRPI0514020A (pt) 2008-05-27

Family

ID=35079333

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0513083-2A BRPI0513083A (pt) 2004-08-06 2005-07-19 oxazolidinonas contendo oxindóis como agentes antibacterianos
BRPI0514020-0A BRPI0514020A (pt) 2004-08-06 2005-07-19 oxindóis oxazolidinonas como agentes antibacterianos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BRPI0513083-2A BRPI0513083A (pt) 2004-08-06 2005-07-19 oxazolidinonas contendo oxindóis como agentes antibacterianos

Country Status (24)

Country Link
US (2) US20080262056A1 (pt)
EP (2) EP1781643A1 (pt)
JP (2) JP2008509126A (pt)
CN (1) CN101001853A (pt)
AP (1) AP2007003904A0 (pt)
AR (1) AR050101A1 (pt)
AU (1) AU2005270951A1 (pt)
BR (2) BRPI0513083A (pt)
CA (2) CA2576041A1 (pt)
EA (1) EA200700322A1 (pt)
GT (1) GT200500204A (pt)
IL (1) IL180957A0 (pt)
MA (1) MA28793B1 (pt)
MX (2) MX2007001526A (pt)
NL (1) NL1029686C2 (pt)
NO (1) NO20071230L (pt)
PA (1) PA8640901A1 (pt)
PE (1) PE20060351A1 (pt)
SV (1) SV2006002180A (pt)
TN (1) TNSN07043A1 (pt)
TW (1) TWI289448B (pt)
UY (1) UY29048A1 (pt)
WO (2) WO2006016220A1 (pt)
ZA (1) ZA200700476B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1869029A1 (en) * 2005-04-06 2007-12-26 Pharmacia & Upjohn Company LLC An oxindole oxazolidinone as antibacterial agent
AU2006231919A1 (en) * 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents
CN103420995B (zh) * 2013-09-07 2015-07-01 吉首大学 噁唑烷酮-烷胺基-呋喃酮型化合物及其制法和用途
CN103483329B (zh) * 2013-09-07 2015-08-05 吉首大学 呋喃酮-芳基-噁唑烷酮型化合物及其制法和用途
CN107698567B (zh) * 2017-10-25 2020-09-15 西南大学 靛红唑醇类化合物及其制备方法和医药应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164510A (en) * 1988-09-15 1992-11-17 The Upjohn Company 5'Indolinyl-5β-amidomethyloxazolidin-2-ones
WO1990002744A1 (en) * 1988-09-15 1990-03-22 The Upjohn Company In position 3 substituted-5-beta-amidomethyl-oxazolidin-2-ones
DE4425612A1 (de) * 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
NZ295528A (en) * 1994-11-15 1999-03-29 Upjohn Co Bicyclic oxazine and thiazine oxazolidinone antibacterials
HRP960159A2 (en) * 1995-04-21 1997-08-31 Bayer Ag Benzocyclopentane oxazolidinones containing heteroatoms
CN1072222C (zh) * 1995-09-01 2001-10-03 法玛西雅厄普约翰公司 以c－c键连接于4－8元杂环环的苯基噁唑烷酮
DE19601265A1 (de) * 1996-01-16 1997-07-17 Bayer Ag 2-Oxo- und 2-Thio-1,2-dihydrochinolinyl-oxazolidinone
DE19601627A1 (de) * 1996-01-18 1997-07-24 Bayer Ag Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
AU3973697A (en) * 1996-08-21 1998-03-06 Pharmacia & Upjohn Company Isoxazoline derivatives useful as antimicrobials
GB9717804D0 (en) * 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
US6239152B1 (en) * 1998-01-23 2001-05-29 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
GB9812019D0 (en) * 1998-06-05 1998-07-29 Zeneca Ltd Chemical compounds
ES2241920T3 (es) * 1999-02-01 2005-11-01 PHARMACIA & UPJOHN COMPANY LLC Derivados de 2-fluoro-(oxido-tiopiran-4-il)benceno.
MXPA01012167A (es) * 1999-05-27 2002-06-21 Upjohn Co Nuevas oxazolidinonas biciclicas como agentes antibacterianos.
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
US7012088B2 (en) * 2003-02-24 2006-03-14 Pharmacia & Upjohn Company Indolone oxazolidinones and derivatives thereof
AU2006231919A1 (en) * 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents

Also Published As

Publication number Publication date
PE20060351A1 (es) 2006-05-03
NL1029686C2 (nl) 2006-07-18
JP2008509125A (ja) 2008-03-27
CA2575702A1 (en) 2006-02-16
EP1781642A1 (en) 2007-05-09
CN101001853A (zh) 2007-07-18
GT200500204A (es) 2006-03-02
JP2008509126A (ja) 2008-03-27
MX2007001526A (es) 2007-03-27
NO20071230L (no) 2007-05-04
MA28793B1 (fr) 2007-08-01
UY29048A1 (es) 2006-03-31
ZA200700476B (en) 2008-10-29
BRPI0513083A (pt) 2008-04-22
AU2005270951A1 (en) 2006-02-16
US20080262056A1 (en) 2008-10-23
SV2006002180A (es) 2006-06-26
TNSN07043A1 (fr) 2008-06-02
US20060030609A1 (en) 2006-02-09
EP1781643A1 (en) 2007-05-09
IL180957A0 (en) 2007-07-04
EA200700322A1 (ru) 2007-08-31
AP2007003904A0 (en) 2007-02-28
TW200612924A (en) 2006-05-01
WO2006016220A1 (en) 2006-02-16
CA2576041A1 (en) 2006-02-16
NL1029686A1 (nl) 2006-02-07
MX2007001568A (es) 2007-04-16
AR050101A1 (es) 2006-09-27
PA8640901A1 (es) 2007-01-17
TWI289448B (en) 2007-11-11
WO2006016221A1 (en) 2006-02-16

Similar Documents

Publication Publication Date Title
DK2123271T3 (da) Lægemiddel til behandling af influenza
ECSP088773A (es) Derivados de amida y su aplicación para el tratamiento de enfermedades relacionadas con proteína-g
UY30499A1 (es) Derivados de amina utiles como agentes anticancerigenos
ATE506354T1 (de) Substituierte arylcyclopropylacetamide als glucokinaseaktivatoren
AR065649A1 (es) Dionas ciclicas herbicidamente activas, procesos de obtencion y composiciones.
MY177250A (en) Novel nicotinamide derivative or salt thereof
UY30387A1 (es) Nuevos compuestos
UY30897A1 (es) Derivados de pentafluorotiobenzamidoacetonitrilo, composiciones conteniéndolos y aplicaciones
PE20081530A1 (es) Nuevos compuestos 617
BR112014007898A2 (pt) derivados de etinila como moduladores alostéricos de mglur5
BRPI1013821A8 (pt) piridinas substituídas como antagonistas de ccr3.
BRPI0809656B8 (pt) atropisômero, composto, agente profilático ou terapêutico, e, composição farmacêutica
SMT201300085B (it) Composti di pirrolo
BR112014031616A2 (pt) compostos de fenoxietil piperidina
EA200802380A1 (ru) Совместные кристаллы пирролидинонов
BR112014004235A2 (pt) derivados de isoxazolina como compostos inseticidas
AR070485A1 (es) Compuestos derivados de azetidinas, su preparacion y su aplicacion en terapeutica
BR112012027387A2 (pt) composição para controle de doenças de plantas e uso da mesma
BR112013021848A2 (pt) 5-(fenil/piridinil-etinil)-2-piridina/2-pirimidina-carboxamidas como moduladores de mglur5
DE602007013730D1 (de) Trehaloseverbindung und arzneimittel mit der verbindung
BR112012013861A2 (pt) ibidores da cisteína protease
TNSN07439A1 (en) Derivatives of,4,5 - diarylpyrrole, preparation method thereof and use of same in therapeutics
BRPI0811220A2 (pt) Compostos terapêuticos
BRPI0514020A (pt) oxindóis oxazolidinonas como agentes antibacterianos
WO2009025265A1 (ja) ピペラジン誘導体

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.