BRPI0515946A - sal de tosilato, sua preparação e uso, bem como composição farmacêutica compreendendo o mesmo - Google Patents

sal de tosilato, sua preparação e uso, bem como composição farmacêutica compreendendo o mesmo

Info

Publication number
BRPI0515946A
BRPI0515946A BRPI0515946-6A BRPI0515946A BRPI0515946A BR PI0515946 A BRPI0515946 A BR PI0515946A BR PI0515946 A BRPI0515946 A BR PI0515946A BR PI0515946 A BRPI0515946 A BR PI0515946A
Authority
BR
Brazil
Prior art keywords
preparation
pharmaceutical composition
same
tosylate salt
well
Prior art date
Application number
BRPI0515946-6A
Other languages
English (en)
Inventor
Alfons Grunenberg
Jana Lenz
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35482258&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0515946(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Publication of BRPI0515946A publication Critical patent/BRPI0515946A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Medicinal Preparation (AREA)
  • Paper (AREA)
  • Catalysts (AREA)
  • Glass Compositions (AREA)

Abstract

'SAL DE TOSILATO, SUA PREPARAçãO E USO, BEM COMO COMPOSIçãO FARMACêUTICA, COMPREENDENDO O MESMO". A presente invenção refere-se a uma nova forma termodinamicamente estável, à temperatura ambiente, do sal de tosilato de 4-{4-¢({¢4-cloro-3-(trifluorometil)fenil!amino}carbonil)amino!fenóxi}-N- metilpiridina-2-carbixamida, para processar sua preparação, para medicamentos que compreendem ele e seu uso no controle de distúrbios.
BRPI0515946-6A 2004-09-29 2005-09-20 sal de tosilato, sua preparação e uso, bem como composição farmacêutica compreendendo o mesmo BRPI0515946A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04023130 2004-09-29
PCT/EP2005/010119 WO2006034797A1 (en) 2004-09-29 2005-09-20 Thermodynamically stable form of bay 43-9006 tosylate

Publications (1)

Publication Number Publication Date
BRPI0515946A true BRPI0515946A (pt) 2008-08-12

Family

ID=35482258

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0515946-6A BRPI0515946A (pt) 2004-09-29 2005-09-20 sal de tosilato, sua preparação e uso, bem como composição farmacêutica compreendendo o mesmo

Country Status (32)

Country Link
US (1) US8877933B2 (pt)
EP (1) EP1797038B1 (pt)
JP (2) JP5215666B2 (pt)
KR (4) KR101239489B1 (pt)
CN (1) CN101065360B (pt)
AR (1) AR051301A1 (pt)
AU (1) AU2005289100B2 (pt)
BR (1) BRPI0515946A (pt)
CA (1) CA2581843C (pt)
CU (1) CU20070068A7 (pt)
CY (1) CY1113598T1 (pt)
DK (1) DK1797038T3 (pt)
EC (1) ECSP077356A (pt)
ES (1) ES2387812T3 (pt)
GT (1) GT200500270A (pt)
HN (1) HN2005000722A (pt)
HR (1) HRP20120662T1 (pt)
IL (1) IL181734A (pt)
MA (1) MA28880B1 (pt)
MY (1) MY176929A (pt)
NO (1) NO344272B1 (pt)
NZ (1) NZ553804A (pt)
PE (3) PE20142042A1 (pt)
PL (1) PL1797038T3 (pt)
PT (1) PT1797038E (pt)
SG (1) SG155996A1 (pt)
SI (1) SI1797038T1 (pt)
TW (1) TWI382016B (pt)
UA (1) UA91520C2 (pt)
UY (1) UY29144A1 (pt)
WO (1) WO2006034797A1 (pt)
ZA (1) ZA200702510B (pt)

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