BRPI0516134A - neurotoxinas de clostridium para uso na cicatrização de tecidos - Google Patents

neurotoxinas de clostridium para uso na cicatrização de tecidos

Info

Publication number
BRPI0516134A
BRPI0516134A BRPI0516134-7A BRPI0516134A BRPI0516134A BR PI0516134 A BRPI0516134 A BR PI0516134A BR PI0516134 A BRPI0516134 A BR PI0516134A BR PI0516134 A BRPI0516134 A BR PI0516134A
Authority
BR
Brazil
Prior art keywords
neurotoxins
clostridium
tissue
damaged
healing
Prior art date
Application number
BRPI0516134-7A
Other languages
English (en)
Inventor
Harold Victor Taylor
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz Pharma Gmbh & Co Kgaa filed Critical Merz Pharma Gmbh & Co Kgaa
Publication of BRPI0516134A publication Critical patent/BRPI0516134A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/08—Clostridium, e.g. Clostridium tetani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Materials For Medical Uses (AREA)

Abstract

NEUROTOXINAS DE CLOSTRIDIUM PARA USO NA CICATRIZAçãO DE TECIDOS. Neurotoxinas de Clostridium de ocorrência natural e/ou modificadas, que incluem aquelas neurotoxinas livres de proteínas de formação de complexo que formam complexos com neurotoxinas de Clostridium, são usadas para melhorar a cicatrização de superfície danificada ou tecido superficial de um paciente por administração local ou na proximidade do tecido danificado. Tais neurotoxinas podem ser vantajosamente empregadas na cicatrização de ferimentos e para evitar a formação de cicatrizes, e têm aplicabilidade na área de oftalmologia, por exemplo, no tratamento de tecido corneano danificado, por exemplo, por fechamento de olhos inflamados. Uma modalidade adicional inclui o uso diagnóstico para a avaliação de administração eficaz de toxina e medicamentos para uso nela.
BRPI0516134-7A 2004-09-27 2005-09-27 neurotoxinas de clostridium para uso na cicatrização de tecidos BRPI0516134A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61339204P 2004-09-27 2004-09-27
PCT/GB2005/003728 WO2006035225A1 (en) 2004-09-27 2005-09-27 Clostridial neurotoxins for use in tissue healing

Publications (1)

Publication Number Publication Date
BRPI0516134A true BRPI0516134A (pt) 2008-08-26

Family

ID=35355850

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0516134-7A BRPI0516134A (pt) 2004-09-27 2005-09-27 neurotoxinas de clostridium para uso na cicatrização de tecidos

Country Status (13)

Country Link
US (1) US20060067950A1 (pt)
EP (1) EP1799254A1 (pt)
KR (1) KR20070057862A (pt)
CN (1) CN101027083A (pt)
AU (1) AU2005288758A1 (pt)
BR (1) BRPI0516134A (pt)
CA (1) CA2580122A1 (pt)
EA (1) EA200700739A1 (pt)
IL (1) IL182153A0 (pt)
MX (1) MX2007003407A (pt)
NO (1) NO20072155L (pt)
WO (1) WO2006035225A1 (pt)
ZA (1) ZA200702484B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7220422B2 (en) * 2003-05-20 2007-05-22 Allergan, Inc. Methods and compositions for treating eye disorders
US20050220821A1 (en) * 2004-03-31 2005-10-06 Allergan, Inc. Pressure sore treatment
US10792344B2 (en) 2006-06-29 2020-10-06 Merz Pharma Gmbh & Co. Kgaa High frequency application of botulinum toxin therapy
AR061669A1 (es) 2006-06-29 2008-09-10 Merz Pharma Gmbh & Co Kgaa Aplicacion de alta frecuencia de terapia con toxina botulinica
EP2236520A1 (en) * 2009-03-31 2010-10-06 Leukocare Ag Stabilizing composition for immobilized biomolecules
US10076558B2 (en) 2014-02-18 2018-09-18 Rnw Skn, Llc Prophylactic normalization of cutaneous wound repair
CA3057302A1 (en) * 2017-03-22 2018-09-27 Bonti, Inc. Botulinum neurotoxin serotype e for use in cosmetic treatment
CA3057304A1 (en) * 2017-03-22 2018-09-27 Bonti, Inc. Botulinum neurotoxins for treating traumatic injuries
CN107469065B (zh) * 2017-07-19 2021-05-18 广州医科大学 类蛇毒三胜肽在制备用于治疗皮肤溃疡的药物中的应用
US20190183987A1 (en) * 2017-12-18 2019-06-20 Bonti, Inc. Neurotoxins for use in minimizing scarring

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE216589T1 (de) * 1996-11-27 2002-05-15 William J Binder Neurotoxine zur behandlung von hauterkrankungen bei säugetieren
CA2347828A1 (en) * 1998-10-27 2000-05-04 Mayo Foundation For Medical Education And Research Methods for enhancing wound healing
DE19925739A1 (de) * 1999-06-07 2000-12-21 Biotecon Ges Fuer Biotechnologische Entwicklung & Consulting Mbh Therapeutikum mit einem Botulinum-Neurotoxin
US8048423B2 (en) * 2003-12-09 2011-11-01 Allergan, Inc. Botulinum toxin therapy for skin disorders

Also Published As

Publication number Publication date
CA2580122A1 (en) 2006-04-06
WO2006035225A1 (en) 2006-04-06
KR20070057862A (ko) 2007-06-07
AU2005288758A1 (en) 2006-04-06
US20060067950A1 (en) 2006-03-30
ZA200702484B (en) 2008-11-26
IL182153A0 (en) 2007-07-24
CN101027083A (zh) 2007-08-29
EP1799254A1 (en) 2007-06-27
EA200700739A1 (ru) 2007-10-26
MX2007003407A (es) 2007-05-23
NO20072155L (no) 2007-04-26

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 3A, 4A, 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012.