BRPI0516955A - ensaio genÈmico - Google Patents

ensaio genÈmico

Info

Publication number
BRPI0516955A
BRPI0516955A BRPI0516955-0A BRPI0516955A BRPI0516955A BR PI0516955 A BRPI0516955 A BR PI0516955A BR PI0516955 A BRPI0516955 A BR PI0516955A BR PI0516955 A BRPI0516955 A BR PI0516955A
Authority
BR
Brazil
Prior art keywords
nucleic acid
acid sequence
probe
providing
markers
Prior art date
Application number
BRPI0516955-0A
Other languages
English (en)
Inventor
Glen H Erikson
Jasmine I Daksis
Original Assignee
Ingeneus Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ingeneus Inc filed Critical Ingeneus Inc
Publication of BRPI0516955A publication Critical patent/BRPI0516955A/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Nanotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

ENSAIO GENÈMICO. Trata-se de um método para detectar uma seqüência de ácido nuclélco em uma amostra genómica que inclui: proporcionar a amostra genómica que contém uma seqúência de ácido nucléico alvo de um ácido nucléico dúplex; proporcionar uma sonda que contém uma seqúência de ácido nucléico de sonda; proporcionar uma mistura de hibridização; irradiar a mistura incubada com radiação eficaz para estimular pelo menos alguns dos marcadores a emitir energia; e detectar a partir de um sinal fluorescente se a sonda se emparelha perfeitamente na seqúência de ácido nucléico alvo, onde a detecção é realizada dentro de sessenta minutos da mistura de hibridização proporcionada, e o método é realizado sem desnaturação e sem amplificação por PCR do ácido nucléico dúplex. Um kit para praticar o método inclui a sonda, o agente promotor de hibridização, e marcadores.
BRPI0516955-0A 2004-09-24 2005-09-23 ensaio genÈmico BRPI0516955A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61267004P 2004-09-24 2004-09-24
PCT/IB2005/053162 WO2006033088A2 (en) 2004-09-24 2005-09-23 Genomic assay

Publications (1)

Publication Number Publication Date
BRPI0516955A true BRPI0516955A (pt) 2008-09-30

Family

ID=36000782

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0516955-0A BRPI0516955A (pt) 2004-09-24 2005-09-23 ensaio genÈmico

Country Status (14)

Country Link
US (1) US8486622B2 (pt)
EP (1) EP1815010A2 (pt)
JP (1) JP2008514197A (pt)
KR (1) KR20070062575A (pt)
CN (1) CN101031659A (pt)
AU (1) AU2005286084C1 (pt)
BR (1) BRPI0516955A (pt)
CA (1) CA2581087C (pt)
IL (1) IL182107A0 (pt)
NZ (1) NZ554538A (pt)
RU (1) RU2464320C2 (pt)
SG (1) SG155995A1 (pt)
WO (1) WO2006033088A2 (pt)
ZA (1) ZA200703326B (pt)

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US8877438B2 (en) 2010-07-20 2014-11-04 California Institute Of Technology Self-assembled polynucleotide structure
US9834439B2 (en) 2010-07-20 2017-12-05 California Institute Of Technology Biomolecular self-assembly
US8962241B2 (en) * 2010-07-20 2015-02-24 California Institute Of Technology Triggered molecular geometry based bioimaging probes
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RU2577107C2 (ru) * 2013-10-04 2016-03-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ поиска белков-мишеней, запускающих процесс канцерогенеза, в образцах тканей индивидуального пациента, для последующей противоопухолевой фармакотерапии
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WO2017131463A1 (en) * 2016-01-26 2017-08-03 Seegene, Inc. . Methods for providing signal for target nucleic acid sequence
RU2637310C1 (ru) * 2016-06-08 2017-12-04 Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) Флуоресцентно-меченые дезоксиуридинтрифосфаты
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AU2017321492A1 (en) 2016-08-30 2019-03-14 California Institute Of Technology Immunohistochemistry via hybridization chain reaction
CN110546273A (zh) * 2017-03-30 2019-12-06 生命技术公司 通过衔接子序列定量ngs dna
CN112162027B (zh) * 2020-09-21 2023-08-18 上海市计量测试技术研究院 一种基于三嵌段探针的电化学传感器及其在检测转基因双链rna中的应用
US11873485B2 (en) 2021-01-26 2024-01-16 California Institute Of Technology Allosteric conditional guide RNAs for cell-selective regulation of CRISPR/Cas

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SG155995A1 (en) 2009-10-29
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CA2581087A1 (en) 2006-03-30
WO2006033088A2 (en) 2006-03-30
JP2008514197A (ja) 2008-05-08
EP1815010A2 (en) 2007-08-08
KR20070062575A (ko) 2007-06-15
AU2005286084B2 (en) 2011-04-28
CN101031659A (zh) 2007-09-05
AU2005286084C1 (en) 2011-11-24
NZ554538A (en) 2009-12-24
IL182107A0 (en) 2007-07-24
WO2006033088A3 (en) 2006-07-06
AU2005286084A1 (en) 2006-03-30
ZA200703326B (en) 2008-11-26
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US20090123914A1 (en) 2009-05-14
US8486622B2 (en) 2013-07-16

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