BRPI0517255A - sistema e método para amostragem e análise de analito com hidrogel - Google Patents
sistema e método para amostragem e análise de analito com hidrogelInfo
- Publication number
- BRPI0517255A BRPI0517255A BRPI0517255-1A BRPI0517255A BRPI0517255A BR PI0517255 A BRPI0517255 A BR PI0517255A BR PI0517255 A BRPI0517255 A BR PI0517255A BR PI0517255 A BRPI0517255 A BR PI0517255A
- Authority
- BR
- Brazil
- Prior art keywords
- analyte
- biological membrane
- hydrogel
- electrode assembly
- medium
- Prior art date
Links
- 239000012491 analyte Substances 0.000 title abstract 8
- 239000000017 hydrogel Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 238000005070 sampling Methods 0.000 title abstract 2
- 239000012528 membrane Substances 0.000 abstract 4
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 abstract 2
- 229920000936 Agarose Polymers 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 125000004386 diacrylate group Chemical group 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 229910052697 platinum Inorganic materials 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 229920000671 polyethylene glycol diacrylate Polymers 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- C08L33/24—Homopolymers or copolymers of amides or imides
- C08L33/26—Homopolymers or copolymers of acrylamide or methacrylamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
- A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
- A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6802—Sensor mounted on worn items
- A61B5/681—Wristwatch-type devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/048—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/145—Hydrogels or hydrocolloids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- C08L33/24—Homopolymers or copolymers of amides or imides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3273—Devices therefor, e.g. test element readers, circuitry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/4166—Systems measuring a particular property of an electrolyte
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2203/00—Applications
- C08L2203/02—Applications for biomedical use
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
- Y10T436/144444—Glucose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Optics & Photonics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Electrochemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Dispersion Chemistry (AREA)
- Hematology (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
SISTEMA E MéTODO PARA AMOSTRAGEM E ANáLISE DE ANALITO COM HIDROGEL. A invenção refere-se a um sistema de monitoramento de analito transdérmico compreendendo um meio adaptado para interface com uma membrana biológica para receber um analito da membrana biológica e um conjunto de eletrodo compreendendo uma pluralidade de eletrodos, em que o meio é adaptado para reagir continuamente com o analito, um sinal elétrico é detectado pelo conjunto de eletrodo e o sinal elétrico se correlaciona com um valor do analito. O valor do analito pode ser o fluxo do analito através da membrana biológica ou a concentração do analito em um fluido corporal de um indivíduo. O meio pode compreender um hidrogel baseado em acetato de vinila, um hidrogel baseado em agarose ou um hidrogel baseado em diacrilato de polietileno glicol (PEG-DA), por exemplo. A região de superfície do eletrodo pode compreender platina pura. O sistema pode incluir um filtro de interferência localizado entre a membrana biológica e o conjunto de eletrodo para redução de interferência no sistema. O sistema pode compreender um processador programado para implementar um método de correção de erro que corrige um desvio no sensor.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97496304A | 2004-10-28 | 2004-10-28 | |
| US20133405A | 2005-08-11 | 2005-08-11 | |
| US11/223,971 US8224414B2 (en) | 2004-10-28 | 2005-09-13 | System and method for analyte sampling and analysis with hydrogel |
| PCT/US2005/038785 WO2006050032A2 (en) | 2004-10-28 | 2005-10-27 | System and method for analyte sampling and analysis with hydrogel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0517255A true BRPI0517255A (pt) | 2008-10-07 |
Family
ID=36262984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0517255-1A BRPI0517255A (pt) | 2004-10-28 | 2005-10-27 | sistema e método para amostragem e análise de analito com hidrogel |
Country Status (4)
| Country | Link |
|---|---|
| US (9) | US20060094944A1 (pt) |
| JP (1) | JP5815652B2 (pt) |
| BR (1) | BRPI0517255A (pt) |
| NZ (1) | NZ554624A (pt) |
Families Citing this family (205)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6036924A (en) | 1997-12-04 | 2000-03-14 | Hewlett-Packard Company | Cassette of lancet cartridges for sampling blood |
| US6391005B1 (en) | 1998-03-30 | 2002-05-21 | Agilent Technologies, Inc. | Apparatus and method for penetration with shaft having a sensor for sensing penetration depth |
| DE10057832C1 (de) | 2000-11-21 | 2002-02-21 | Hartmann Paul Ag | Blutanalysegerät |
| US8641644B2 (en) | 2000-11-21 | 2014-02-04 | Sanofi-Aventis Deutschland Gmbh | Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means |
| US9427532B2 (en) | 2001-06-12 | 2016-08-30 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
| ATE494837T1 (de) | 2001-06-12 | 2011-01-15 | Pelikan Technologies Inc | Integriertes system zur blutprobenanalyse mit mehrfach verwendbarem probennahmemodul |
| US8337419B2 (en) | 2002-04-19 | 2012-12-25 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
| JP4209767B2 (ja) | 2001-06-12 | 2009-01-14 | ペリカン テクノロジーズ インコーポレイテッド | 皮膚の性状の一時的変化に対する適応手段を備えた自動最適化形切開器具 |
| US7981056B2 (en) | 2002-04-19 | 2011-07-19 | Pelikan Technologies, Inc. | Methods and apparatus for lancet actuation |
| ATE485766T1 (de) | 2001-06-12 | 2010-11-15 | Pelikan Technologies Inc | Elektrisches betätigungselement für eine lanzette |
| AU2002348683A1 (en) | 2001-06-12 | 2002-12-23 | Pelikan Technologies, Inc. | Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge |
| US9795747B2 (en) | 2010-06-02 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Methods and apparatus for lancet actuation |
| US9226699B2 (en) | 2002-04-19 | 2016-01-05 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling module with a continuous compression tissue interface surface |
| EP1404232B1 (en) | 2001-06-12 | 2009-12-02 | Pelikan Technologies Inc. | Blood sampling apparatus and method |
| US7025774B2 (en) | 2001-06-12 | 2006-04-11 | Pelikan Technologies, Inc. | Tissue penetration device |
| DE60239132D1 (de) | 2001-06-12 | 2011-03-24 | Pelikan Technologies Inc | Gerät zur erhöhung der erfolgsrate im hinblick auf die durch einen fingerstich erhaltene blutausbeute |
| NZ512367A (en) * | 2001-06-14 | 2005-05-27 | Horticulture & Food Res Inst | Non-invasive transudate extraction |
| US7344894B2 (en) | 2001-10-16 | 2008-03-18 | Agilent Technologies, Inc. | Thermal regulation of fluidic samples within a diagnostic cartridge |
| US7613491B2 (en) | 2002-05-22 | 2009-11-03 | Dexcom, Inc. | Silicone based membranes for use in implantable glucose sensors |
| US10022078B2 (en) | 2004-07-13 | 2018-07-17 | Dexcom, Inc. | Analyte sensor |
| US8364229B2 (en) | 2003-07-25 | 2013-01-29 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
| US7563232B2 (en) | 2002-04-19 | 2009-07-21 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7410468B2 (en) | 2002-04-19 | 2008-08-12 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7909778B2 (en) | 2002-04-19 | 2011-03-22 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7141058B2 (en) | 2002-04-19 | 2006-11-28 | Pelikan Technologies, Inc. | Method and apparatus for a body fluid sampling device using illumination |
| US8784335B2 (en) | 2002-04-19 | 2014-07-22 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling device with a capacitive sensor |
| US7371247B2 (en) | 2002-04-19 | 2008-05-13 | Pelikan Technologies, Inc | Method and apparatus for penetrating tissue |
| US7524293B2 (en) | 2002-04-19 | 2009-04-28 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US8702624B2 (en) | 2006-09-29 | 2014-04-22 | Sanofi-Aventis Deutschland Gmbh | Analyte measurement device with a single shot actuator |
| US7331931B2 (en) | 2002-04-19 | 2008-02-19 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7232451B2 (en) | 2002-04-19 | 2007-06-19 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7229458B2 (en) | 2002-04-19 | 2007-06-12 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7481776B2 (en) | 2002-04-19 | 2009-01-27 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7892183B2 (en) | 2002-04-19 | 2011-02-22 | Pelikan Technologies, Inc. | Method and apparatus for body fluid sampling and analyte sensing |
| US8267870B2 (en) | 2002-04-19 | 2012-09-18 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for body fluid sampling with hybrid actuation |
| US7674232B2 (en) | 2002-04-19 | 2010-03-09 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US8579831B2 (en) | 2002-04-19 | 2013-11-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
| US7175642B2 (en) | 2002-04-19 | 2007-02-13 | Pelikan Technologies, Inc. | Methods and apparatus for lancet actuation |
| US7713214B2 (en) | 2002-04-19 | 2010-05-11 | Pelikan Technologies, Inc. | Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing |
| US9314194B2 (en) | 2002-04-19 | 2016-04-19 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
| US9248267B2 (en) | 2002-04-19 | 2016-02-02 | Sanofi-Aventis Deustchland Gmbh | Tissue penetration device |
| US7582099B2 (en) | 2002-04-19 | 2009-09-01 | Pelikan Technologies, Inc | Method and apparatus for penetrating tissue |
| US7291117B2 (en) | 2002-04-19 | 2007-11-06 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7976476B2 (en) | 2002-04-19 | 2011-07-12 | Pelikan Technologies, Inc. | Device and method for variable speed lancet |
| US7717863B2 (en) | 2002-04-19 | 2010-05-18 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7648468B2 (en) | 2002-04-19 | 2010-01-19 | Pelikon Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7297122B2 (en) | 2002-04-19 | 2007-11-20 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7491178B2 (en) | 2002-04-19 | 2009-02-17 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7547287B2 (en) | 2002-04-19 | 2009-06-16 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7901362B2 (en) | 2002-04-19 | 2011-03-08 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US8221334B2 (en) | 2002-04-19 | 2012-07-17 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
| US9795334B2 (en) | 2002-04-19 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
| US7374544B2 (en) | 2002-04-19 | 2008-05-20 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US8574895B2 (en) | 2002-12-30 | 2013-11-05 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus using optical techniques to measure analyte levels |
| ES2490740T3 (es) | 2003-06-06 | 2014-09-04 | Sanofi-Aventis Deutschland Gmbh | Aparato para toma de muestras de fluido sanguíneo y detección de analitos |
| WO2006001797A1 (en) | 2004-06-14 | 2006-01-05 | Pelikan Technologies, Inc. | Low pain penetrating |
| US7604592B2 (en) | 2003-06-13 | 2009-10-20 | Pelikan Technologies, Inc. | Method and apparatus for a point of care device |
| US9763609B2 (en) | 2003-07-25 | 2017-09-19 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
| US8886273B2 (en) | 2003-08-01 | 2014-11-11 | Dexcom, Inc. | Analyte sensor |
| US9135402B2 (en) | 2007-12-17 | 2015-09-15 | Dexcom, Inc. | Systems and methods for processing sensor data |
| US20080119703A1 (en) | 2006-10-04 | 2008-05-22 | Mark Brister | Analyte sensor |
| US7591801B2 (en) | 2004-02-26 | 2009-09-22 | Dexcom, Inc. | Integrated delivery device for continuous glucose sensor |
| US8626257B2 (en) | 2003-08-01 | 2014-01-07 | Dexcom, Inc. | Analyte sensor |
| US20190357827A1 (en) | 2003-08-01 | 2019-11-28 | Dexcom, Inc. | Analyte sensor |
| US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
| EP1671096A4 (en) | 2003-09-29 | 2009-09-16 | Pelikan Technologies Inc | METHOD AND APPARATUS FOR PROVIDING IMPROVED SAMPLE CAPTURING DEVICE |
| WO2005037095A1 (en) | 2003-10-14 | 2005-04-28 | Pelikan Technologies, Inc. | Method and apparatus for a variable user interface |
| US8615282B2 (en) | 2004-07-13 | 2013-12-24 | Dexcom, Inc. | Analyte sensor |
| US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
| US8423114B2 (en) | 2006-10-04 | 2013-04-16 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
| US8287453B2 (en) | 2003-12-05 | 2012-10-16 | Dexcom, Inc. | Analyte sensor |
| US8425417B2 (en) | 2003-12-05 | 2013-04-23 | Dexcom, Inc. | Integrated device for continuous in vivo analyte detection and simultaneous control of an infusion device |
| US8425416B2 (en) | 2006-10-04 | 2013-04-23 | Dexcom, Inc. | Analyte sensor |
| US8364230B2 (en) | 2006-10-04 | 2013-01-29 | Dexcom, Inc. | Analyte sensor |
| US11633133B2 (en) | 2003-12-05 | 2023-04-25 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
| US8364231B2 (en) | 2006-10-04 | 2013-01-29 | Dexcom, Inc. | Analyte sensor |
| US7822454B1 (en) | 2005-01-03 | 2010-10-26 | Pelikan Technologies, Inc. | Fluid sampling device with improved analyte detecting member configuration |
| US8668656B2 (en) | 2003-12-31 | 2014-03-11 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for improving fluidic flow and sample capture |
| US8808228B2 (en) | 2004-02-26 | 2014-08-19 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor |
| US8828203B2 (en) | 2004-05-20 | 2014-09-09 | Sanofi-Aventis Deutschland Gmbh | Printable hydrogels for biosensors |
| US9820684B2 (en) | 2004-06-03 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for a fluid sampling device |
| US7946984B2 (en) | 2004-07-13 | 2011-05-24 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US7783333B2 (en) | 2004-07-13 | 2010-08-24 | Dexcom, Inc. | Transcutaneous medical device with variable stiffness |
| US20060253097A1 (en) * | 2004-10-21 | 2006-11-09 | Braig James R | Methods of treating diabetes |
| US20060094944A1 (en) * | 2004-10-28 | 2006-05-04 | Sontra Medical Corporation | System and method for analyte sampling and analysis with error correction |
| US9788771B2 (en) | 2006-10-23 | 2017-10-17 | Abbott Diabetes Care Inc. | Variable speed sensor insertion devices and methods of use |
| US8652831B2 (en) | 2004-12-30 | 2014-02-18 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for analyte measurement test time |
| US7545272B2 (en) | 2005-02-08 | 2009-06-09 | Therasense, Inc. | RF tag on test strips, test strip vials and boxes |
| US8133178B2 (en) | 2006-02-22 | 2012-03-13 | Dexcom, Inc. | Analyte sensor |
| JP2007037868A (ja) * | 2005-08-05 | 2007-02-15 | Transcutaneous Technologies Inc | 経皮投与装置及びその制御方法 |
| CN101365374B (zh) | 2005-08-31 | 2011-11-16 | 弗吉尼亚大学专利基金委员会 | 改善连续式葡萄糖传感器的准确度 |
| US20070083094A1 (en) * | 2005-10-11 | 2007-04-12 | Colburn Joel C | Medical sensor and technique for using the same |
| US7432069B2 (en) * | 2005-12-05 | 2008-10-07 | Sontra Medical Corporation | Biocompatible chemically crosslinked hydrogels for glucose sensing |
| CN101454667B (zh) | 2005-12-27 | 2013-04-24 | 拜尔保健有限公司 | 使用带有至少一个孔的基板的电化学传感器系统及其制造方法 |
| WO2007123707A1 (en) * | 2006-03-30 | 2007-11-01 | Tti Ellebeau, Inc. | Controlled release membrane and methods of use |
| US8219173B2 (en) | 2008-09-30 | 2012-07-10 | Abbott Diabetes Care Inc. | Optimizing analyte sensor calibration |
| US8224415B2 (en) | 2009-01-29 | 2012-07-17 | Abbott Diabetes Care Inc. | Method and device for providing offset model based calibration for analyte sensor |
| US9675290B2 (en) | 2012-10-30 | 2017-06-13 | Abbott Diabetes Care Inc. | Sensitivity calibration of in vivo sensors used to measure analyte concentration |
| US7653425B2 (en) | 2006-08-09 | 2010-01-26 | Abbott Diabetes Care Inc. | Method and system for providing calibration of an analyte sensor in an analyte monitoring system |
| US9101264B2 (en) | 2006-06-15 | 2015-08-11 | Peerbridge Health, Inc. | Wireless electrode arrangement and method for patient monitoring via electrocardiography |
| US20070299617A1 (en) * | 2006-06-27 | 2007-12-27 | Willis John P | Biofouling self-compensating biosensor |
| US9119582B2 (en) | 2006-06-30 | 2015-09-01 | Abbott Diabetes Care, Inc. | Integrated analyte sensor and infusion device and methods therefor |
| US20080058701A1 (en) * | 2006-07-05 | 2008-03-06 | Transcutaneous Technologies Inc. | Delivery device having self-assembling dendritic polymers and method of use thereof |
| EP2061553A2 (en) * | 2006-09-05 | 2009-05-27 | Tti Ellebeau, Inc. | Impedance systems, devices and methods for evaluating iontophoretic properties of compounds |
| US8214030B2 (en) | 2006-09-06 | 2012-07-03 | Encore Medical Asset Corporation | Iontophoresis apparatus and method |
| US7996077B2 (en) * | 2006-09-06 | 2011-08-09 | Encore Medical Asset Corporation | Iontophoresis apparatus and method |
| GB0619322D0 (en) * | 2006-09-30 | 2006-11-08 | Greater Glasgow Nhs Board | Apparatus for coupling an ultrasound probe to an object |
| US8275438B2 (en) | 2006-10-04 | 2012-09-25 | Dexcom, Inc. | Analyte sensor |
| US8562528B2 (en) | 2006-10-04 | 2013-10-22 | Dexcom, Inc. | Analyte sensor |
| US8478377B2 (en) | 2006-10-04 | 2013-07-02 | Dexcom, Inc. | Analyte sensor |
| US8447376B2 (en) | 2006-10-04 | 2013-05-21 | Dexcom, Inc. | Analyte sensor |
| US8449464B2 (en) | 2006-10-04 | 2013-05-28 | Dexcom, Inc. | Analyte sensor |
| US8298142B2 (en) | 2006-10-04 | 2012-10-30 | Dexcom, Inc. | Analyte sensor |
| WO2008087884A1 (ja) * | 2007-01-16 | 2008-07-24 | Tti Ellebeau, Inc. | 薬物投与量の予測方法及びそのプログラム |
| KR101433550B1 (ko) * | 2007-03-07 | 2014-08-27 | 에코 테라퓨틱스, 인크. | 경피 피분석물 모니터링 시스템 및 피분석물 검출 방법 |
| US7713196B2 (en) * | 2007-03-09 | 2010-05-11 | Nellcor Puritan Bennett Llc | Method for evaluating skin hydration and fluid compartmentalization |
| NZ580997A (en) | 2007-04-27 | 2011-08-26 | Echo Therapeutics Inc | Dermal abrasion device with feedback electrode to deliver data on skin thickness and removable abrasion heads |
| US8239166B2 (en) | 2007-05-14 | 2012-08-07 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
| US20200037874A1 (en) | 2007-05-18 | 2020-02-06 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
| US8562558B2 (en) | 2007-06-08 | 2013-10-22 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor |
| EP4159114B1 (en) | 2007-10-09 | 2024-04-10 | DexCom, Inc. | Integrated insulin delivery system with continuous glucose sensor |
| US8417312B2 (en) | 2007-10-25 | 2013-04-09 | Dexcom, Inc. | Systems and methods for processing sensor data |
| US8290559B2 (en) | 2007-12-17 | 2012-10-16 | Dexcom, Inc. | Systems and methods for processing sensor data |
| EP2252196A4 (en) | 2008-02-21 | 2013-05-15 | Dexcom Inc | SYSTEMS AND METHOD FOR PROCESSING, TRANSMITTING AND DISPLAYING SENSOR DATA |
| US8396528B2 (en) | 2008-03-25 | 2013-03-12 | Dexcom, Inc. | Analyte sensor |
| US9386944B2 (en) | 2008-04-11 | 2016-07-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for analyte detecting device |
| CN105380662B (zh) * | 2008-07-31 | 2018-06-12 | 希森美康株式会社 | 用于测定活体内成分的方法、装置及收集部件 |
| EP2341953B1 (en) * | 2008-09-04 | 2018-11-21 | The General Hospital Corporation | Hydrogels for vocal cord and soft tissue augmentation and repair |
| EP2206462A1 (en) * | 2009-01-13 | 2010-07-14 | Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO | A non-invasive chemical sensor, a skin patch, a packaging material and a monitoring system using the same |
| US9375169B2 (en) | 2009-01-30 | 2016-06-28 | Sanofi-Aventis Deutschland Gmbh | Cam drive for managing disposable penetrating member actions with a single motor and motor and control system |
| US20100198034A1 (en) | 2009-02-03 | 2010-08-05 | Abbott Diabetes Care Inc. | Compact On-Body Physiological Monitoring Devices and Methods Thereof |
| FI3714788T3 (fi) * | 2009-02-26 | 2023-04-25 | Abbott Diabetes Care Inc | Parannettujen analyyttisensorien valmistusmenetelmä |
| ES2884623T3 (es) * | 2009-07-23 | 2021-12-10 | Abbott Diabetes Care Inc | Procedimiento de fabricación y sistema de medición continua de analitos |
| WO2011014851A1 (en) | 2009-07-31 | 2011-02-03 | Abbott Diabetes Care Inc. | Method and apparatus for providing analyte monitoring system calibration accuracy |
| JP5795584B2 (ja) | 2009-08-31 | 2015-10-14 | アボット ダイアベティス ケア インコーポレイテッドAbbott Diabetes Care Inc. | 医療用装置 |
| EP2473098A4 (en) | 2009-08-31 | 2014-04-09 | Abbott Diabetes Care Inc | ANALYTICAL SIGNAL PROCESSING APPARATUS AND METHOD |
| JP5406646B2 (ja) * | 2009-09-16 | 2014-02-05 | シスメックス株式会社 | 組織液収集方法に用いる組織液収集キット及び組織液収集シート |
| WO2011041463A2 (en) | 2009-09-30 | 2011-04-07 | Dexcom, Inc. | Transcutaneous analyte sensor |
| WO2011084607A1 (en) | 2009-12-17 | 2011-07-14 | Bayer Healthcare Llc | Transdermal systems, devices, and methods for biological analysis |
| US9354226B2 (en) | 2009-12-17 | 2016-05-31 | Ascensia Diabetes Care Holdings Ag | Transdermal systems, devices, and methods to optically analyze an analyte |
| US9198568B2 (en) | 2010-03-04 | 2015-12-01 | The General Hospital Corporation | Methods and systems of matching voice deficits with a tunable mucosal implant to restore and enhance individualized human sound and voice production |
| EP4434458A3 (en) | 2010-03-24 | 2024-12-18 | Abbott Diabetes Care, Inc. | Medical device inserters |
| US8965476B2 (en) | 2010-04-16 | 2015-02-24 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
| WO2011156095A2 (en) * | 2010-06-10 | 2011-12-15 | The Regents Of The University Of California | Textile-based printable electrodes for electrochemical sensing |
| KR101743320B1 (ko) | 2011-02-28 | 2017-06-02 | 쿠퍼비젼 인터내셔날 홀딩 캄파니, 엘피 | 실리콘 히드로겔 콘택트 렌즈 |
| US20120265036A1 (en) | 2011-04-15 | 2012-10-18 | Dexcom, Inc. | Advanced analyte sensor calibration and error detection |
| DE102011101583B4 (de) * | 2011-05-12 | 2014-09-11 | Otto Bock Healthcare Gmbh | Elektrode zum transkutanen Übertragen elektrischer Signale und Verfahren zum Herstellen einer solchen |
| WO2013032940A1 (en) | 2011-08-26 | 2013-03-07 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| JP2013078463A (ja) * | 2011-10-04 | 2013-05-02 | Canon Inc | 音響波取得装置 |
| DK3831283T3 (da) | 2011-12-11 | 2023-05-30 | Abbott Diabetes Care Inc | Analytsensorindretninger, forbindelser og fremgangsmåder |
| US9199201B2 (en) * | 2011-12-15 | 2015-12-01 | General Electric Company | Self contained electroosmotic pump and method of making thereof |
| US9462970B2 (en) | 2012-04-24 | 2016-10-11 | Abbott Diabetes Care Inc. | Methods of lag-compensation for analyte measurements, and devices related thereto |
| GB2505694B (en) * | 2012-09-07 | 2017-03-22 | Lifescan Scotland Ltd | Electrochemical-based analytical test strip with bare interferent electrodes |
| WO2014052136A1 (en) | 2012-09-26 | 2014-04-03 | Abbott Diabetes Care Inc. | Method and apparatus for improving lag correction during in vivo measurement of analyte concentration with analyte concentration variability and range data |
| WO2014164731A1 (en) | 2013-03-11 | 2014-10-09 | University Of Utah Research Foundation | Sensor systems |
| CN105228522B (zh) | 2013-03-14 | 2018-06-26 | 萨诺智能公司 | 用于生物监测的人体上的微传感器 |
| US10820860B2 (en) | 2013-03-14 | 2020-11-03 | One Drop Biosensor Technologies, Llc | On-body microsensor for biomonitoring |
| US9750445B2 (en) | 2013-06-28 | 2017-09-05 | Verily Life Sciences Llc | Porous polymeric formulation prepared using porogens |
| US9828620B2 (en) | 2013-06-28 | 2017-11-28 | Verily Life Sciences Llc | Porous polymeric formulation prepared using monomer |
| US9763605B2 (en) | 2013-11-27 | 2017-09-19 | Verily Life Sciences Llc | Adjustment of sensor sensitivity by controlling copolymer film thickness through a controlled drying step |
| US9617578B2 (en) | 2013-12-06 | 2017-04-11 | Verily Life Sciences Llc | Sensor membrane with low temperature coefficient |
| US10595754B2 (en) | 2014-03-13 | 2020-03-24 | Sano Intelligence, Inc. | System for monitoring body chemistry |
| US20150257685A1 (en) | 2014-03-13 | 2015-09-17 | Sano Intelligence, Inc. | System for monitoring body chemistry |
| US10321858B2 (en) * | 2014-08-18 | 2019-06-18 | Proteadx, Inc. | Apparatus and methods for transdermal sensing of analytes in interstitial fluid and associated data transmission systems |
| US10598624B2 (en) | 2014-10-23 | 2020-03-24 | Abbott Diabetes Care Inc. | Electrodes having at least one sensing structure and methods for making and using the same |
| US10987039B2 (en) * | 2014-12-03 | 2021-04-27 | Stmicroelectronics S.R.L. | Microneedle array device and method of making |
| TWI571238B (zh) * | 2015-01-16 | 2017-02-21 | 亞洲大學 | 非侵入式代謝產物偵測裝置 |
| GB201507508D0 (en) * | 2015-04-30 | 2015-06-17 | Inside Biometrics Ltd | Electrochemical Test Device |
| EP3294134B1 (en) | 2015-05-14 | 2020-07-08 | Abbott Diabetes Care Inc. | Inserter system for a compact medical device and corresponding method |
| US10213139B2 (en) | 2015-05-14 | 2019-02-26 | Abbott Diabetes Care Inc. | Systems, devices, and methods for assembling an applicator and sensor control device |
| US11432750B2 (en) | 2016-03-14 | 2022-09-06 | Abbott Diabetes Care Inc. | In vivo enzyme activity sensors and methods |
| KR102673720B1 (ko) | 2016-07-29 | 2024-06-07 | 삼성전자주식회사 | 혈중 물질 추정 장치 및 방법 |
| KR102638309B1 (ko) | 2016-10-26 | 2024-02-19 | 삼성전자주식회사 | 웨어러블 장치 및 헬스 모니터링 방법 |
| EP3570735A4 (en) | 2017-01-23 | 2020-10-21 | Abbott Diabetes Care Inc. | SYSTEMS, DEVICES AND METHODS FOR INSERTING ANALYTE SENSOR |
| CN115644863A (zh) | 2017-05-03 | 2023-01-31 | 雅培糖尿病护理公司 | 具有传感器数据的基于持续期的调整的系统、装置及方法 |
| JP7164548B2 (ja) | 2017-05-09 | 2022-11-01 | アセンシア・ディアベティス・ケア・ホールディングス・アーゲー | 持続血糖モニターのためのセンサー組立体装置および方法 |
| WO2018227006A1 (en) * | 2017-06-09 | 2018-12-13 | The Regents Of The University Of California | Implantable biosensor |
| US11116898B2 (en) | 2017-06-26 | 2021-09-14 | Abbott Diabetes Care Inc. | Artificial pancreas integrated CGM architectures and designs |
| FI3668400T3 (fi) | 2017-08-18 | 2023-08-29 | Abbott Diabetes Care Inc | Menetelmä analyyttianturien yksilölliseen kalibrointiin |
| US11331022B2 (en) | 2017-10-24 | 2022-05-17 | Dexcom, Inc. | Pre-connected analyte sensors |
| CN111246797B (zh) | 2017-10-24 | 2025-09-09 | 德克斯康公司 | 预连接分析物传感器 |
| US11918348B2 (en) | 2017-12-05 | 2024-03-05 | Abbott Diabetes Care Inc. | Medical devices having a dynamic surface profile and methods for production and use thereof |
| EP4585143A3 (en) | 2018-06-07 | 2025-10-01 | Abbott Diabetes Care, Inc. | Focused sterilization and sterilized sub-assemblies for analyte monitoring systems |
| DK4218567T3 (da) | 2018-06-07 | 2025-03-31 | Abbott Diabetes Care Inc | Fokuseret sterilisering og steriliserede underenheder til analytovervågningssystemer |
| IT201800008035A1 (it) * | 2018-08-10 | 2020-02-10 | Università Campus Bio-Medico Di Roma | Funzionalizzazione innovativa su sensori in fase liquida per la rilevazione di lipidi bioattivi |
| MX2021007294A (es) | 2018-12-21 | 2021-07-15 | Abbott Diabetes Care Inc | Sistemas, dispositivos y metodos para la insercion de sensores de analito. |
| JP7494194B2 (ja) | 2019-02-05 | 2024-06-03 | アセンシア・ディアベティス・ケア・ホールディングス・アーゲー | 連続的分析物感知および自動較正のセンサ動作を精査するための装置および方法 |
| EP3928089B1 (en) | 2019-02-22 | 2025-05-14 | Ascensia Diabetes Care Holdings AG | Method and system for glucose concentration monitoring using harmonic relationships |
| US11963763B2 (en) | 2019-09-10 | 2024-04-23 | Ascensia Diabetes Care Holdings Ag | Methods and apparatus information gathering, error detection and analyte concentration determination during continuous analyte sensing |
| MY208843A (en) * | 2020-03-26 | 2025-06-02 | Univ Malaya | An electrochemical sensor for detecting and characterizing a biological material |
| US12667286B2 (en) | 2020-06-16 | 2026-06-30 | Abbott Diabetes Care Inc. | Analyte sensors featuring working electrode asperity planing for decreasing interferent signal |
| CA3182587A1 (en) | 2020-07-08 | 2022-01-13 | Stephen OJA | Analyte sensors featuring enhancements for decreasing interferent signal |
| MY192294A (en) | 2020-08-31 | 2022-08-17 | Abbott Diabetes Care Inc | Systems, devices, and methods for analyte sensor insertion |
| CA3186905A1 (en) | 2020-09-15 | 2022-03-24 | Abbott Diabetes Care Inc. | Systems, devices, and methods for an analyte sensor |
| EP4413917B1 (en) | 2020-09-15 | 2025-12-03 | Abbott Diabetes Care Inc. | Systems, devices, and methods for analyte monitoring |
| CN116897015A (zh) | 2020-12-23 | 2023-10-17 | 雅培糖尿病护理公司 | 具有减少的干扰物信号的分析物传感器和方法 |
| CA3197901A1 (en) | 2020-12-30 | 2022-07-07 | Steven Mitchell | Devices for analyte monitoring |
| JP2024502548A (ja) | 2020-12-31 | 2024-01-22 | アボット ダイアベティス ケア インコーポレイテッド | 医療モニタシステムに埋め込まれたシステム |
| USD1086030S1 (en) | 2021-04-21 | 2025-07-29 | One Health Biosensing Inc. | Charging station |
| USD1076079S1 (en) | 2021-04-21 | 2025-05-20 | One Health Biosensing Inc. | Applicator assembly |
| USD988882S1 (en) | 2021-04-21 | 2023-06-13 | Informed Data Systems Inc. | Sensor assembly |
| EP4370029A1 (en) | 2021-07-16 | 2024-05-22 | Abbott Diabetes Care Inc. | Systems, devices, and methods for analyte monitoring |
| KR102869392B1 (ko) * | 2021-11-29 | 2025-10-14 | 서강대학교산학협력단 | 실리카-하이드로젤 복합체 및 이를 포함하는 센서 |
| US12702332B2 (en) | 2022-01-04 | 2026-08-11 | Abbott Diabetes Care Inc. | Systems, devices, and methods for analyte monitoring |
| WO2026090211A1 (en) * | 2024-10-21 | 2026-04-30 | The Regents Of The University Of Colorado, A Body Corporate | Selective gas transport through high pressure liquid membranes |
Family Cites Families (207)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3305514A (en) * | 1964-02-06 | 1967-02-21 | Standard Oil Co | Vinyl halide resin, epoxy or alkyd resin, monoalkenyl and polyalkenyl monomer reinforced thermoplastic composition |
| US3397192A (en) * | 1966-05-18 | 1968-08-13 | Gaf Corp | Alkoxy-and aryloxy-ethylated polymers of heterocyclic nu-vinyl monomers and process of preparing the same |
| US3551554A (en) | 1968-08-16 | 1970-12-29 | Crown Zellerbach Corp | Enhancing tissue penetration of physiologically active agents with dmso |
| US3711606A (en) | 1970-09-02 | 1973-01-16 | Crown Zellerbach Corp | Enhancing tissue penetration of physiologically active steroidal agents with dmso |
| US3711602A (en) * | 1970-10-30 | 1973-01-16 | Crown Zellerbach Corp | Compositions for topical application for enhancing tissue penetration of physiologically active agents with dmso |
| US4002221A (en) | 1972-09-19 | 1977-01-11 | Gilbert Buchalter | Method of transmitting ultrasonic impulses to surface using transducer coupling agent |
| US3828769A (en) | 1973-02-28 | 1974-08-13 | H Mettler | Method and apparatus for ultrasonic treatment of lower tissues simultaneous with heating of subcutaneous, outer muscle and lower tissues |
| SU445433A1 (ru) | 1973-03-22 | 1974-10-05 | Центральный Научно-Исследовательский Институт Курортологии И Физиотерапии | Способ физиотерапевтического лечени больных с заболевани ми опорно-двигательного аппарата обменного характера |
| SU506421A1 (ru) | 1974-08-06 | 1978-03-05 | Московское Ордена Ленина И Ордена Трудового Красного Знамени Высшее Техническое Училище Имени Н.Э.Баумана | Способ лечени инфицированных ран |
| US4020830A (en) * | 1975-03-12 | 1977-05-03 | The University Of Utah | Selective chemical sensitive FET transducers |
| US4144646A (en) * | 1975-12-05 | 1979-03-20 | Lion Hamigaki Kabushiki Kaisha | Torsional ultrasonic vibrators |
| FR2336116A1 (fr) | 1975-12-22 | 1977-07-22 | Lion Hamigaki Kk | Dispositif de traitement dentaire par ultrasons |
| SU556805A1 (ru) | 1976-01-23 | 1977-05-05 | Каунасский Медицинский Институт | Способ введени лекарственных веществ |
| GB1577551A (en) | 1976-02-09 | 1980-10-22 | Fahim M | Medication for topical application by ultrasound |
| US4309989A (en) | 1976-02-09 | 1982-01-12 | The Curators Of The University Of Missouri | Topical application of medication by ultrasound with coupling agent |
| SU591186A1 (ru) | 1976-07-23 | 1978-02-05 | Serov Vilenin Nikolaevich | Устройство дл лечени заболеваний глаз |
| DE2756460A1 (de) | 1977-12-17 | 1979-06-21 | Fraunhofer Ges Forschung | Verfahren zur lokal begrenzten applikation von therpeutika durch die oberflaeche von lebenden koerpern oder koerperorganen |
| US4176664A (en) | 1978-03-13 | 1979-12-04 | Stanley Kalish | Impregnated bandage |
| US4280494A (en) * | 1979-06-26 | 1981-07-28 | Cosgrove Robert J Jun | System for automatic feedback-controlled administration of drugs |
| US4249531A (en) * | 1979-07-05 | 1981-02-10 | Alza Corporation | Bioerodible system for delivering drug manufactured from poly(carboxylic acid) |
| SU910157A1 (ru) | 1980-02-29 | 1982-03-07 | Московское Ордена Ленина,Ордена Трудового Красного Знамени Высшее Техническое Училище Им.Баумана | Способ лечени инфицированных ран |
| CA1165240A (en) | 1980-07-09 | 1984-04-10 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions |
| US4372296A (en) | 1980-11-26 | 1983-02-08 | Fahim Mostafa S | Treatment of acne and skin disorders and compositions therefor |
| US4457748A (en) | 1982-01-11 | 1984-07-03 | Medtronic, Inc. | Non-invasive diagnosis method |
| JPS59102393A (ja) * | 1982-12-01 | 1984-06-13 | Mitsubishi Petrochem Co Ltd | 固定化酵素の製造方法 |
| US4537776A (en) * | 1983-06-21 | 1985-08-27 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone |
| DE3324835A1 (de) * | 1983-07-09 | 1985-01-17 | Cassella Ag, 6000 Frankfurt | Vernetztes copolymerisat, verfahren zu seiner herstellung und seine verwendung als sorptionsmittel |
| US4563184A (en) | 1983-10-17 | 1986-01-07 | Bernard Korol | Synthetic resin wound dressing and method of treatment using same |
| US4557943A (en) | 1983-10-31 | 1985-12-10 | Advanced Semiconductor Materials America, Inc. | Metal-silicide deposition using plasma-enhanced chemical vapor deposition |
| US4646725A (en) * | 1983-11-16 | 1987-03-03 | Manoutchehr Moasser | Method for treating herpes lesions and other infectious skin conditions |
| US4605670A (en) | 1984-02-01 | 1986-08-12 | Nitto Electric Industrial Co., Ltd. | Method for percutaneously administering metoclopramide |
| US4732153A (en) | 1984-07-18 | 1988-03-22 | Michael Phillips | Transdermal dosimeter |
| DK8601218A (pt) | 1984-07-18 | 1986-03-17 | ||
| US4779806A (en) | 1984-07-23 | 1988-10-25 | Massachusetts Institute Of Technology | Ultrasonically modulated polymeric devices for delivering compositions |
| US4657543A (en) | 1984-07-23 | 1987-04-14 | Massachusetts Institute Of Technology | Ultrasonically modulated polymeric devices for delivering compositions |
| US4834978A (en) * | 1984-10-01 | 1989-05-30 | Biotek, Inc. | Method of transdermal drug delivery |
| US4698058A (en) | 1985-10-15 | 1987-10-06 | Albert R. Greenfeld | Ultrasonic self-cleaning catheter system for indwelling drains and medication supply |
| US4683242A (en) | 1985-10-28 | 1987-07-28 | A. H. Robins Company, Incorporated | Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters |
| DE246341T1 (de) | 1986-05-20 | 1989-03-30 | Massachusetts Institute Of Technology, Cambridge, Mass. | Bioerodierbare erzeugnisse zur verwendung als implantate oder prothese mit einem voraussehbaren resorbierungsgrad. |
| GB8612861D0 (en) | 1986-05-27 | 1986-07-02 | Cambridge Life Sciences | Immobilised enzyme biosensors |
| US4981779A (en) * | 1986-06-26 | 1991-01-01 | Becton, Dickinson And Company | Apparatus for monitoring glucose |
| US4767402A (en) | 1986-07-08 | 1988-08-30 | Massachusetts Institute Of Technology | Ultrasound enhancement of transdermal drug delivery |
| US4948587A (en) | 1986-07-08 | 1990-08-14 | Massachusetts Institute Of Technology | Ultrasound enhancement of transbuccal drug delivery |
| JPS6336172A (ja) | 1986-07-29 | 1988-02-16 | Toshiba Corp | 超音波カプラ |
| US4863970A (en) | 1986-11-14 | 1989-09-05 | Theratech, Inc. | Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols |
| US5489625A (en) * | 1986-11-19 | 1996-02-06 | Sunstar Kabushiki Kaisha | Dental adhesive coating base composition and oral composition |
| JPS63132889A (ja) | 1986-11-21 | 1988-06-04 | Tanabe Seiyaku Co Ltd | キナゾリノン誘導体 |
| US4786277A (en) | 1986-11-21 | 1988-11-22 | Trustees Of Boston University | Electrodes, electrode assemblies, methods, and systems for tissue stimulation |
| JPS63135179A (ja) | 1986-11-26 | 1988-06-07 | 立花 俊郎 | 薬物の経皮投与具 |
| US5001051A (en) * | 1986-12-12 | 1991-03-19 | Regents Of The University Of California | Dose critical in-vivo detection of anti-cancer drug levels in blood |
| US5006342A (en) | 1986-12-22 | 1991-04-09 | Cygnus Corporation | Resilient transdermal drug delivery device |
| EP0278599A3 (en) | 1987-02-02 | 1988-12-07 | Seiko Epson Corporation | Photographic transfer type image forming apparatus |
| US4787888A (en) | 1987-06-01 | 1988-11-29 | University Of Connecticut | Disposable piezoelectric polymer bandage for percutaneous delivery of drugs and method for such percutaneous delivery (a) |
| US4780212A (en) | 1987-07-31 | 1988-10-25 | Massachusetts Institute Of Technology | Ultrasound enchancement of membrane permeability |
| US4821733A (en) | 1987-08-18 | 1989-04-18 | Dermal Systems International | Transdermal detection system |
| US4820720A (en) | 1987-08-24 | 1989-04-11 | Alza Corporation | Transdermal drug composition with dual permeation enhancers |
| US4805623A (en) | 1987-09-04 | 1989-02-21 | Vander Corporation | Spectrophotometric method for quantitatively determining the concentration of a dilute component in a light- or other radiation-scattering environment |
| JPH01140054A (ja) * | 1987-11-26 | 1989-06-01 | Nec Corp | グルコースセンサ |
| DE68925030T2 (de) * | 1988-01-21 | 1996-07-25 | Massachusetts Inst Technology | Molekültransport durch gewebe mit der verwendung von elektroporation. |
| US5362307A (en) * | 1989-01-24 | 1994-11-08 | The Regents Of The University Of California | Method for the iontophoretic non-invasive-determination of the in vivo concentration level of an inorganic or organic substance |
| WO1989006989A1 (en) * | 1988-01-29 | 1989-08-10 | The Regents Of The University Of California | Iontophoretic non-invasive sampling or delivery device |
| US4866050A (en) | 1988-04-27 | 1989-09-12 | Ben Amoz Daniel | Ultrasonic transdermal application of steroid compositions |
| US5078144A (en) * | 1988-08-19 | 1992-01-07 | Olympus Optical Co. Ltd. | System for applying ultrasonic waves and a treatment instrument to a body part |
| US5076273A (en) | 1988-09-08 | 1991-12-31 | Sudor Partners | Method and apparatus for determination of chemical species in body fluid |
| EP0363504A1 (en) * | 1988-10-10 | 1990-04-18 | Dräger Nederland B.V. | Method of providing a substrate with a layer comprising a polyvinylbased hydrogel and a biochemically active material |
| US5008110A (en) | 1988-11-10 | 1991-04-16 | The Procter & Gamble Company | Storage-stable transdermal patch |
| US5250419A (en) | 1988-12-16 | 1993-10-05 | L'oreal | Method for the direct measurement of at least one chemical parameter of skin using a biosensor |
| US5086229A (en) | 1989-01-19 | 1992-02-04 | Futrex, Inc. | Non-invasive measurement of blood glucose |
| US4933062A (en) | 1989-03-07 | 1990-06-12 | University Of Connecticut | Modified composite electrodes with renewable surface for electrochemical applications and method of making same |
| US4953552A (en) | 1989-04-21 | 1990-09-04 | Demarzo Arthur P | Blood glucose monitoring system |
| US5118404A (en) * | 1989-04-28 | 1992-06-02 | Nec Corporation | Enzyme electrode and a method of determining concentration of an analyte in a sample solution |
| US5139023A (en) * | 1989-06-02 | 1992-08-18 | Theratech Inc. | Apparatus and method for noninvasive blood glucose monitoring |
| US5120544A (en) | 1989-06-19 | 1992-06-09 | Henley International, Inc. | Crosslinked hydrogel and method for making same |
| US5069908A (en) | 1989-06-19 | 1991-12-03 | Henley International, Inc. | Crosslinked hydrogel and method for making same |
| US4986271A (en) | 1989-07-19 | 1991-01-22 | The University Of New Mexico | Vivo refillable glucose sensor |
| US5050604A (en) | 1989-10-16 | 1991-09-24 | Israel Reshef | Apparatus and method for monitoring the health condition of a subject |
| US5140985A (en) | 1989-12-11 | 1992-08-25 | Schroeder Jon M | Noninvasive blood glucose measuring device |
| US5016615A (en) | 1990-02-20 | 1991-05-21 | Riverside Research Institute | Local application of medication with ultrasound |
| CA2196746A1 (en) | 1990-02-23 | 1991-08-24 | The Regents Of The University Of California | Ultrasound-enhanced delivery of materials through the skin |
| US5115805A (en) * | 1990-02-23 | 1992-05-26 | Cygnus Therapeutic Systems | Ultrasound-enhanced delivery of materials into and through the skin |
| US5231975A (en) | 1990-02-23 | 1993-08-03 | Cygnus Therapeutic Systems | Ultrasound-enhanced delivery of materials into and through the skin |
| JP3046346B2 (ja) | 1990-03-12 | 2000-05-29 | 昭和電工株式会社 | 外用剤基剤又は補助剤とそれを含有する人又は動物の外用剤 |
| US5165407A (en) | 1990-04-19 | 1992-11-24 | The University Of Kansas | Implantable glucose sensor |
| US5161532A (en) | 1990-04-19 | 1992-11-10 | Teknekron Sensor Development Corporation | Integral interstitial fluid sensor |
| US5119819A (en) * | 1990-05-02 | 1992-06-09 | Miles Inc. | Method and apparatus for non-invasive monitoring of blood glucose |
| DE69110467T2 (de) * | 1990-06-15 | 1996-02-01 | Cortrak Medical Inc | Vorrichtung zur abgabe von medikamenten. |
| US5197946A (en) * | 1990-06-27 | 1993-03-30 | Shunro Tachibana | Injection instrument with ultrasonic oscillating element |
| US5236410A (en) | 1990-08-02 | 1993-08-17 | Ferrotherm International, Inc. | Tumor treatment method |
| WO1992006701A1 (en) * | 1990-10-18 | 1992-04-30 | Huffstutler, M., Conrad, Jr. | Preparation of concentrated fluid symphytum extracts, therapeutic forms and methods of use |
| JP2646848B2 (ja) | 1990-11-30 | 1997-08-27 | 日本電気株式会社 | グルコースセンサの測定方法 |
| US5135753A (en) * | 1991-03-12 | 1992-08-04 | Pharmetrix Corporation | Method and therapeutic system for smoking cessation |
| DE69215722T3 (de) | 1991-03-22 | 2001-03-08 | Katsuro Tachibana | Verstärker zur Ultraschalltherapie von Erkrankungen sowie diesen enthaltende flüssige Arzneimittelzusammensetzungen |
| JP2684871B2 (ja) | 1991-05-16 | 1997-12-03 | 日本電気株式会社 | 体液成分測定方法および測定装置 |
| JP3181071B2 (ja) * | 1991-06-28 | 2001-07-03 | 俊郎 立花 | 血液処理装置 |
| US5171215A (en) | 1991-08-22 | 1992-12-15 | Flanagan Dennis F | Endermic method and apparatus |
| US5215520A (en) | 1991-09-17 | 1993-06-01 | Centre Internationale De Recherches Dermatologiques Galderma (C.I.R.D. Galderma) | Method for delivering an active substance topically or percutaneously |
| AU3070892A (en) | 1991-11-12 | 1993-06-15 | Nepera, Inc. | Adhesive hydrogels having extended use lives and process for the preparation of same |
| US5230334A (en) | 1992-01-22 | 1993-07-27 | Summit Technology, Inc. | Method and apparatus for generating localized hyperthermia |
| US5470582A (en) | 1992-02-07 | 1995-11-28 | Syntex (U.S.A.) Inc. | Controlled delivery of pharmaceuticals from preformed porous polymeric microparticles |
| US5165418B1 (en) | 1992-03-02 | 1999-12-14 | Nikola I Tankovich | Blood sampling device and method using a laser |
| US5405614A (en) * | 1992-04-08 | 1995-04-11 | International Medical Associates, Inc. | Electronic transdermal drug delivery system |
| US5334640A (en) * | 1992-04-08 | 1994-08-02 | Clover Consolidated, Ltd. | Ionically covalently crosslinked and crosslinkable biocompatible encapsulation compositions and methods |
| US5534496A (en) | 1992-07-07 | 1996-07-09 | University Of Southern California | Methods and compositions to enhance epithelial drug transport |
| JPH0670987A (ja) | 1992-08-28 | 1994-03-15 | Katsuro Tachibana | 薬物投与・体液採取ユニット及び装置 |
| US5421816A (en) * | 1992-10-14 | 1995-06-06 | Endodermic Medical Technologies Company | Ultrasonic transdermal drug delivery system |
| US5364838A (en) | 1993-01-29 | 1994-11-15 | Miris Medical Corporation | Method of administration of insulin |
| US5386837A (en) * | 1993-02-01 | 1995-02-07 | Mmtc, Inc. | Method for enhancing delivery of chemotherapy employing high-frequency force fields |
| US5267985A (en) | 1993-02-11 | 1993-12-07 | Trancell, Inc. | Drug delivery by multiple frequency phonophoresis |
| CA2114968A1 (en) | 1993-02-25 | 1994-08-26 | John Wille | Transdermal treatment with mast cell degranulating agents for drug-induced hypersensitivity |
| US5667487A (en) | 1993-04-07 | 1997-09-16 | Henley; Julian L. | Ionosonic drug delivery apparatus |
| AU7107394A (en) | 1993-07-16 | 1995-02-13 | Cygnus Therapeutic Systems | Noninvasive glucose monitor |
| US5413550A (en) | 1993-07-21 | 1995-05-09 | Pti, Inc. | Ultrasound therapy system with automatic dose control |
| US5415629A (en) * | 1993-09-15 | 1995-05-16 | Henley; Julian L. | Programmable apparatus for the transdermal delivery of drugs and method |
| US5582184A (en) | 1993-10-13 | 1996-12-10 | Integ Incorporated | Interstitial fluid collection and constituent measurement |
| DE69322968T2 (de) | 1993-10-22 | 1999-07-08 | Rijksuniversiteit Te Groningen, Groningen | Verfahren und Vorrichtung zur kontinuierlichen Überwachung eines Anolytpegels |
| US5458140A (en) | 1993-11-15 | 1995-10-17 | Non-Invasive Monitoring Company (Nimco) | Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers |
| US5814599A (en) | 1995-08-04 | 1998-09-29 | Massachusetts Insitiute Of Technology | Transdermal delivery of encapsulated drugs |
| US5885211A (en) | 1993-11-15 | 1999-03-23 | Spectrix, Inc. | Microporation of human skin for monitoring the concentration of an analyte |
| US5445611A (en) | 1993-12-08 | 1995-08-29 | Non-Invasive Monitoring Company (Nimco) | Enhancement of transdermal delivery with ultrasound and chemical enhancers |
| US5443080A (en) | 1993-12-22 | 1995-08-22 | Americate Transtech, Inc. | Integrated system for biological fluid constituent analysis |
| US5771890A (en) * | 1994-06-24 | 1998-06-30 | Cygnus, Inc. | Device and method for sampling of substances using alternating polarity |
| US5429735A (en) * | 1994-06-27 | 1995-07-04 | Miles Inc. | Method of making and amperometric electrodes |
| US5569198A (en) | 1995-01-23 | 1996-10-29 | Cortrak Medical Inc. | Microporous catheter |
| US5626554A (en) * | 1995-02-21 | 1997-05-06 | Exogen, Inc. | Gel containment structure |
| US5573778A (en) | 1995-03-17 | 1996-11-12 | Adhesives Research, Inc. | Drug flux enhancer-tolerant pressure sensitive adhesive composition |
| US5646221A (en) | 1995-03-31 | 1997-07-08 | Kowa Co., Ltd. | Adhesive base material |
| US5773146A (en) * | 1995-06-05 | 1998-06-30 | Ppg Industries, Inc. | Forming size compositions, glass fibers coated with the same and fabrics woven from such coated fibers |
| PT840597E (pt) | 1995-07-12 | 2004-02-27 | Cygnus Therapeutic Systems | Penso de hidrogel |
| US20040062759A1 (en) * | 1995-07-12 | 2004-04-01 | Cygnus, Inc. | Hydrogel formulations for use in electroosmotic extraction and detection of glucose |
| US6041253A (en) * | 1995-12-18 | 2000-03-21 | Massachusetts Institute Of Technology | Effect of electric field and ultrasound for transdermal drug delivery |
| US5947921A (en) | 1995-12-18 | 1999-09-07 | Massachusetts Institute Of Technology | Chemical and physical enhancers and ultrasound for transdermal drug delivery |
| US6002961A (en) | 1995-07-25 | 1999-12-14 | Massachusetts Institute Of Technology | Transdermal protein delivery using low-frequency sonophoresis |
| US5906830A (en) | 1995-09-08 | 1999-05-25 | Cygnus, Inc. | Supersaturated transdermal drug delivery systems, and methods for manufacturing the same |
| US5989409A (en) | 1995-09-11 | 1999-11-23 | Cygnus, Inc. | Method for glucose sensing |
| US5735273A (en) | 1995-09-12 | 1998-04-07 | Cygnus, Inc. | Chemical signal-impermeable mask |
| US5902603A (en) * | 1995-09-14 | 1999-05-11 | Cygnus, Inc. | Polyurethane hydrogel drug reservoirs for use in transdermal drug delivery systems, and associated methods of manufacture and use |
| US6689265B2 (en) | 1995-10-11 | 2004-02-10 | Therasense, Inc. | Electrochemical analyte sensors using thermostable soybean peroxidase |
| US5618275A (en) * | 1995-10-27 | 1997-04-08 | Sonex International Corporation | Ultrasonic method and apparatus for cosmetic and dermatological applications |
| US5711861A (en) * | 1995-11-22 | 1998-01-27 | Ward; W. Kenneth | Device for monitoring changes in analyte concentration |
| CA2212826C (en) | 1995-12-28 | 2002-02-19 | Cygnus, Inc. | Methods for monitoring a physiological analyte |
| DE19602861C2 (de) | 1996-01-28 | 1997-12-11 | Meinhard Prof Dr Knoll | Probenahmesystem für in Trägerflüssigkeiten enthaltene Analyte sowie Verfahren zu seiner Herstellung |
| US6009343A (en) | 1996-02-23 | 1999-12-28 | Abbott Laboratories | Enhanced transdermal transport of fluid using vacuum |
| US5655539A (en) | 1996-02-26 | 1997-08-12 | Abbott Laboratories | Method for conducting an ultrasound procedure using an ultrasound transmissive pad |
| US5656016A (en) | 1996-03-18 | 1997-08-12 | Abbott Laboratories | Sonophoretic drug delivery system |
| JP2002515786A (ja) | 1996-06-28 | 2002-05-28 | ソントラ メディカル,エル.ピー. | 経皮輸送の超音波増強 |
| US6375932B1 (en) * | 1996-09-10 | 2002-04-23 | Mitsubishi Chemical Corporation | Hair cosmetic composition containing amine-oxide polymer |
| US7105352B2 (en) | 1996-11-06 | 2006-09-12 | University Of Pittsburgh | Intelligent polymerized crystalline colloidal array carbohydrate sensors |
| US6063039A (en) | 1996-12-06 | 2000-05-16 | Abbott Laboratories | Method and apparatus for obtaining blood for diagnostic tests |
| US6558321B1 (en) * | 1997-03-04 | 2003-05-06 | Dexcom, Inc. | Systems and methods for remote monitoring and modulation of medical devices |
| US5961451A (en) | 1997-04-07 | 1999-10-05 | Motorola, Inc. | Noninvasive apparatus having a retaining member to retain a removable biosensor |
| EP0975390B1 (en) | 1997-04-14 | 2005-03-09 | The University of Alabama at Birmingham Research Foundation | Implantable triphasic waveform defibrillator |
| US6153211A (en) * | 1997-07-18 | 2000-11-28 | Infimed, Inc. | Biodegradable macromers for the controlled release of biologically active substances |
| US5851438A (en) | 1997-08-29 | 1998-12-22 | E. I. Du Pont De Nemours And Company | Thick film compositions for making medical electrodes |
| US6503198B1 (en) | 1997-09-11 | 2003-01-07 | Jack L. Aronowtiz | Noninvasive transdermal systems for detecting an analyte obtained from or underneath skin and methods |
| US6117643A (en) * | 1997-11-25 | 2000-09-12 | Ut Battelle, Llc | Bioluminescent bioreporter integrated circuit |
| US6579690B1 (en) * | 1997-12-05 | 2003-06-17 | Therasense, Inc. | Blood analyte monitoring through subcutaneous measurement |
| US7066884B2 (en) | 1998-01-08 | 2006-06-27 | Sontra Medical, Inc. | System, method, and device for non-invasive body fluid sampling and analysis |
| AU740999B2 (en) * | 1998-01-08 | 2001-11-22 | Sontra Medical, Inc. | Sonophoretic enhanced transdermal transport |
| US20060015058A1 (en) | 1998-01-08 | 2006-01-19 | Kellogg Scott C | Agents and methods for enhancement of transdermal transport |
| US8287483B2 (en) | 1998-01-08 | 2012-10-16 | Echo Therapeutics, Inc. | Method and apparatus for enhancement of transdermal transport |
| US6038464A (en) | 1998-02-09 | 2000-03-14 | Axelgaard Manufacturing Co., Ltd. | Medical electrode |
| DE19806642A1 (de) * | 1998-02-18 | 1999-08-19 | Huels Chemische Werke Ag | Biosensor mit neuartiger Passivierungsschicht |
| US6587705B1 (en) | 1998-03-13 | 2003-07-01 | Lynn Kim | Biosensor, iontophoretic sampling system, and methods of use thereof |
| JP3600158B2 (ja) * | 1998-05-13 | 2004-12-08 | シグナス, インコーポレイテッド | 生理学的分析物のモニタリング |
| ATE220936T1 (de) * | 1998-05-13 | 2002-08-15 | Cygnus Therapeutic Systems | Sammelvorrichtungen für transdermale probennahmesysteme |
| US6233471B1 (en) | 1998-05-13 | 2001-05-15 | Cygnus, Inc. | Signal processing for measurement of physiological analysis |
| US6535753B1 (en) * | 1998-08-20 | 2003-03-18 | Microsense International, Llc | Micro-invasive method for painless detection of analytes in extra-cellular space |
| WO2000013573A1 (en) | 1998-09-04 | 2000-03-16 | Powderject Research Limited | Monitoring methods using particle delivery methods |
| US6468229B1 (en) | 1998-10-20 | 2002-10-22 | Abbott Laboratories | Apparatus and method for the collection of interstitial fluids |
| US20040171980A1 (en) | 1998-12-18 | 2004-09-02 | Sontra Medical, Inc. | Method and apparatus for enhancement of transdermal transport |
| US6223471B1 (en) * | 1998-12-31 | 2001-05-01 | Jerry Keith Barber | Sliding door with wheel repair kit |
| EP1064046A1 (en) | 1999-04-22 | 2001-01-03 | Cygnus, Inc. | Methods and devices for removing interfering species |
| WO2000078992A2 (en) * | 1999-06-18 | 2000-12-28 | Therasense, Inc. | Mass transport limited in vivo analyte sensor |
| DE19933611A1 (de) * | 1999-07-17 | 2001-01-18 | Aventis Res & Tech Gmbh & Co | Verfahren zur Herstellung von Aminen durch homogen katalysierte reduktive Aminierung von Carbonylverbindungen |
| US6251083B1 (en) * | 1999-09-07 | 2001-06-26 | Amira Medical | Interstitial fluid methods and devices for determination of an analyte in the body |
| BR0108042A (pt) | 2000-02-01 | 2002-10-29 | Spectrx Inc | Membranas de limitação de difusão de analito fundido usando monÈmeros hidrófilos fotopolimerizáveis |
| JP2003527613A (ja) | 2000-03-17 | 2003-09-16 | ソントラ・メディカル・インコーポレーテッド | 体液の非侵襲性のサンプリングおよび分析のためのシステム、方法およびデバイス |
| DE10021139B4 (de) * | 2000-04-29 | 2005-06-30 | Basf Coatings Ag | Mehrkomponentenbeschichtungsstoffe, -klebstoffe und -dichtungsmassen und ihre Verwendung |
| US6442413B1 (en) * | 2000-05-15 | 2002-08-27 | James H. Silver | Implantable sensor |
| US7181261B2 (en) | 2000-05-15 | 2007-02-20 | Silver James H | Implantable, retrievable, thrombus minimizing sensors |
| US6459917B1 (en) * | 2000-05-22 | 2002-10-01 | Ashok Gowda | Apparatus for access to interstitial fluid, blood, or blood plasma components |
| US6540675B2 (en) * | 2000-06-27 | 2003-04-01 | Rosedale Medical, Inc. | Analyte monitor |
| US6585765B1 (en) * | 2000-06-29 | 2003-07-01 | Advanced Cardiovascular Systems, Inc. | Implantable device having substances impregnated therein and a method of impregnating the same |
| US6394965B1 (en) * | 2000-08-15 | 2002-05-28 | Carbon Medical Technologies, Inc. | Tissue marking using biocompatible microparticles |
| DE10047989A1 (de) * | 2000-09-28 | 2002-04-18 | Basf Coatings Ag | Thermisch und mit aktinischer Strahlung härtbare Mehrkomponentenbeschichtungsstoffe, -klebstoffe und -dichtungsmassen und ihre Verwendung |
| US6487447B1 (en) | 2000-10-17 | 2002-11-26 | Ultra-Sonic Technologies, L.L.C. | Method and apparatus for in-vivo transdermal and/or intradermal delivery of drugs by sonoporation |
| ATE438418T1 (de) * | 2001-05-01 | 2009-08-15 | Av Topchiev Inst Petrochemical | Hydrogel-zusammensetzungen |
| US6837988B2 (en) | 2001-06-12 | 2005-01-04 | Lifescan, Inc. | Biological fluid sampling and analyte measurement devices and methods |
| US6875613B2 (en) * | 2001-06-12 | 2005-04-05 | Lifescan, Inc. | Biological fluid constituent sampling and measurement devices and methods |
| US6766817B2 (en) | 2001-07-25 | 2004-07-27 | Tubarc Technologies, Llc | Fluid conduction utilizing a reversible unsaturated siphon with tubarc porosity action |
| AU2002314790A1 (en) * | 2001-12-05 | 2003-06-23 | Dow Global Technologies Inc. | Method for immobilizing a biologic in a polyurethane-hydrogel composition, a composition prepared from the method, and biomedical applications |
| US20030113934A1 (en) * | 2001-12-17 | 2003-06-19 | Sung-Yun Kwon | Diagnostic sensing apparatus |
| WO2003078947A2 (en) * | 2002-03-15 | 2003-09-25 | The Penn State Research Foundation | Method for control of temperature-sensitivity of polymers in solution |
| US6887239B2 (en) | 2002-04-17 | 2005-05-03 | Sontra Medical Inc. | Preparation for transmission and reception of electrical signals |
| US6960617B2 (en) | 2002-04-22 | 2005-11-01 | Purdue Research Foundation | Hydrogels having enhanced elasticity and mechanical strength properties |
| US7150975B2 (en) * | 2002-08-19 | 2006-12-19 | Animas Technologies, Llc | Hydrogel composition for measuring glucose flux |
| US6931327B2 (en) * | 2003-08-01 | 2005-08-16 | Dexcom, Inc. | System and methods for processing analyte sensor data |
| US20050070688A1 (en) * | 2003-09-26 | 2005-03-31 | 3M Innovative Properties Company | Reactive hydrophilic oligomers |
| US7384984B2 (en) * | 2003-12-10 | 2008-06-10 | 3M Innovative Properties Company | Reactive hydrophilic oligomers |
| US7074839B2 (en) * | 2004-03-01 | 2006-07-11 | 3M Innovative Properties Company | Crosslinkable hydrophilic materials from reactive oligomers having pendent photoinitiator groups |
| US7342047B2 (en) * | 2004-03-02 | 2008-03-11 | 3M Innovative Properties Company | Crosslinkable hydrophilic materials from reactive oligomers having pendent unsaturated groups |
| US20060094944A1 (en) | 2004-10-28 | 2006-05-04 | Sontra Medical Corporation | System and method for analyte sampling and analysis with error correction |
| US20080154007A1 (en) * | 2004-12-28 | 2008-06-26 | Kaneka Corporation | Cross-Linked Polymer Particle and Manufacturing Method Thereof |
| US7335690B2 (en) * | 2005-01-25 | 2008-02-26 | 3M Innovative Properties Company | Crosslinkable hydrophilic materials from polymers having pendent Michael donor groups |
| US8609131B2 (en) * | 2005-01-25 | 2013-12-17 | 3M Innovative Properties Company | Absorbent dressing comprising hydrophilic polymer prepared via Michael reaction |
| BRPI0619833A2 (pt) * | 2005-12-16 | 2011-10-18 | Bayer Healthcare Llc | conjunto de sensor de analisado transdérmico e métodos de uso do mesmo |
| DK2540225T3 (en) * | 2007-05-30 | 2015-10-12 | Bayer Healthcare Llc | A process for producing a multilayer coating |
-
2005
- 2005-09-13 US US11/223,957 patent/US20060094944A1/en not_active Abandoned
- 2005-09-13 US US11/223,971 patent/US8224414B2/en not_active Expired - Fee Related
- 2005-09-13 US US11/223,960 patent/US20060094945A1/en not_active Abandoned
- 2005-10-27 US US11/666,270 patent/US9549697B2/en active Active
- 2005-10-27 NZ NZ554624A patent/NZ554624A/en not_active IP Right Cessation
- 2005-10-27 BR BRPI0517255-1A patent/BRPI0517255A/pt not_active Application Discontinuation
-
2013
- 2013-12-03 JP JP2013250328A patent/JP5815652B2/ja not_active Expired - Fee Related
-
2016
- 2016-08-23 US US15/244,837 patent/US10227485B2/en not_active Expired - Lifetime
- 2016-12-16 US US15/381,578 patent/US10196512B2/en not_active Expired - Lifetime
-
2018
- 2018-12-28 US US16/235,342 patent/US10647846B2/en not_active Expired - Lifetime
-
2019
- 2019-01-03 US US16/238,964 patent/US10655004B2/en not_active Expired - Lifetime
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2020
- 2020-04-14 US US16/847,883 patent/US10988610B2/en not_active Expired - Lifetime
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| US9549697B2 (en) | 2017-01-24 |
| US10196512B2 (en) | 2019-02-05 |
| US20170145203A1 (en) | 2017-05-25 |
| US20200362158A1 (en) | 2020-11-19 |
| US20060094945A1 (en) | 2006-05-04 |
| US20060094944A1 (en) | 2006-05-04 |
| US20160376431A1 (en) | 2016-12-29 |
| US10655004B2 (en) | 2020-05-19 |
| US20190136037A1 (en) | 2019-05-09 |
| US8224414B2 (en) | 2012-07-17 |
| US10227485B2 (en) | 2019-03-12 |
| US20060094946A1 (en) | 2006-05-04 |
| NZ554624A (en) | 2010-11-26 |
| JP2014057885A (ja) | 2014-04-03 |
| US20190136038A1 (en) | 2019-05-09 |
| JP5815652B2 (ja) | 2015-11-17 |
| US10647846B2 (en) | 2020-05-12 |
| US10988610B2 (en) | 2021-04-27 |
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