BRPI0517255A - sistema e método para amostragem e análise de analito com hidrogel - Google Patents
sistema e método para amostragem e análise de analito com hidrogelInfo
- Publication number
- BRPI0517255A BRPI0517255A BRPI0517255-1A BRPI0517255A BRPI0517255A BR PI0517255 A BRPI0517255 A BR PI0517255A BR PI0517255 A BRPI0517255 A BR PI0517255A BR PI0517255 A BRPI0517255 A BR PI0517255A
- Authority
- BR
- Brazil
- Prior art keywords
- analyte
- biological membrane
- hydrogel
- electrode assembly
- medium
- Prior art date
Links
- 239000012491 analyte Substances 0.000 title abstract 8
- 239000000017 hydrogel Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 238000005070 sampling Methods 0.000 title abstract 2
- 239000012528 membrane Substances 0.000 abstract 4
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 abstract 2
- 229920000936 Agarose Polymers 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 125000004386 diacrylate group Chemical group 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 229910052697 platinum Inorganic materials 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 229920000671 polyethylene glycol diacrylate Polymers 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- C08L33/24—Homopolymers or copolymers of amides or imides
- C08L33/26—Homopolymers or copolymers of acrylamide or methacrylamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
- A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
- A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6802—Sensor mounted on worn items
- A61B5/681—Wristwatch-type devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/048—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/145—Hydrogels or hydrocolloids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- C08L33/24—Homopolymers or copolymers of amides or imides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3273—Devices therefor, e.g. test element readers, circuitry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/4166—Systems measuring a particular property of an electrolyte
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2203/00—Applications
- C08L2203/02—Applications for biomedical use
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
- Y10T436/144444—Glucose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Optics & Photonics (AREA)
- Electrochemistry (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
SISTEMA E MéTODO PARA AMOSTRAGEM E ANáLISE DE ANALITO COM HIDROGEL. A invenção refere-se a um sistema de monitoramento de analito transdérmico compreendendo um meio adaptado para interface com uma membrana biológica para receber um analito da membrana biológica e um conjunto de eletrodo compreendendo uma pluralidade de eletrodos, em que o meio é adaptado para reagir continuamente com o analito, um sinal elétrico é detectado pelo conjunto de eletrodo e o sinal elétrico se correlaciona com um valor do analito. O valor do analito pode ser o fluxo do analito através da membrana biológica ou a concentração do analito em um fluido corporal de um indivíduo. O meio pode compreender um hidrogel baseado em acetato de vinila, um hidrogel baseado em agarose ou um hidrogel baseado em diacrilato de polietileno glicol (PEG-DA), por exemplo. A região de superfície do eletrodo pode compreender platina pura. O sistema pode incluir um filtro de interferência localizado entre a membrana biológica e o conjunto de eletrodo para redução de interferência no sistema. O sistema pode compreender um processador programado para implementar um método de correção de erro que corrige um desvio no sensor.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97496304A | 2004-10-28 | 2004-10-28 | |
| US20133405A | 2005-08-11 | 2005-08-11 | |
| US11/223,971 US8224414B2 (en) | 2004-10-28 | 2005-09-13 | System and method for analyte sampling and analysis with hydrogel |
| PCT/US2005/038785 WO2006050032A2 (en) | 2004-10-28 | 2005-10-27 | System and method for analyte sampling and analysis with hydrogel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0517255A true BRPI0517255A (pt) | 2008-10-07 |
Family
ID=36262984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0517255-1A BRPI0517255A (pt) | 2004-10-28 | 2005-10-27 | sistema e método para amostragem e análise de analito com hidrogel |
Country Status (4)
| Country | Link |
|---|---|
| US (9) | US20060094944A1 (pt) |
| JP (1) | JP5815652B2 (pt) |
| BR (1) | BRPI0517255A (pt) |
| NZ (1) | NZ554624A (pt) |
Families Citing this family (198)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| US6391005B1 (en) | 1998-03-30 | 2002-05-21 | Agilent Technologies, Inc. | Apparatus and method for penetration with shaft having a sensor for sensing penetration depth |
| US8641644B2 (en) | 2000-11-21 | 2014-02-04 | Sanofi-Aventis Deutschland Gmbh | Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means |
| DE10057832C1 (de) | 2000-11-21 | 2002-02-21 | Hartmann Paul Ag | Blutanalysegerät |
| US7981056B2 (en) | 2002-04-19 | 2011-07-19 | Pelikan Technologies, Inc. | Methods and apparatus for lancet actuation |
| US7041068B2 (en) | 2001-06-12 | 2006-05-09 | Pelikan Technologies, Inc. | Sampling module device and method |
| US9427532B2 (en) | 2001-06-12 | 2016-08-30 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
| WO2002100254A2 (en) | 2001-06-12 | 2002-12-19 | Pelikan Technologies, Inc. | Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge |
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| ATE494837T1 (de) | 2001-06-12 | 2011-01-15 | Pelikan Technologies Inc | Integriertes system zur blutprobenanalyse mit mehrfach verwendbarem probennahmemodul |
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- 2005-09-13 US US11/223,960 patent/US20060094945A1/en not_active Abandoned
- 2005-10-27 NZ NZ554624A patent/NZ554624A/en not_active IP Right Cessation
- 2005-10-27 BR BRPI0517255-1A patent/BRPI0517255A/pt not_active Application Discontinuation
- 2005-10-27 US US11/666,270 patent/US9549697B2/en active Active
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2013
- 2013-12-03 JP JP2013250328A patent/JP5815652B2/ja not_active Expired - Fee Related
-
2016
- 2016-08-23 US US15/244,837 patent/US10227485B2/en not_active Expired - Lifetime
- 2016-12-16 US US15/381,578 patent/US10196512B2/en not_active Expired - Lifetime
-
2018
- 2018-12-28 US US16/235,342 patent/US10647846B2/en not_active Expired - Lifetime
-
2019
- 2019-01-03 US US16/238,964 patent/US10655004B2/en not_active Expired - Lifetime
-
2020
- 2020-04-14 US US16/847,883 patent/US10988610B2/en not_active Expired - Lifetime
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|---|---|
| US20170145203A1 (en) | 2017-05-25 |
| US20060094946A1 (en) | 2006-05-04 |
| US10227485B2 (en) | 2019-03-12 |
| US20080311670A1 (en) | 2008-12-18 |
| US10655004B2 (en) | 2020-05-19 |
| US20190136037A1 (en) | 2019-05-09 |
| US20060094944A1 (en) | 2006-05-04 |
| US20160376431A1 (en) | 2016-12-29 |
| US10196512B2 (en) | 2019-02-05 |
| US10988610B2 (en) | 2021-04-27 |
| US10647846B2 (en) | 2020-05-12 |
| NZ554624A (en) | 2010-11-26 |
| US9549697B2 (en) | 2017-01-24 |
| US20060094945A1 (en) | 2006-05-04 |
| US20190136038A1 (en) | 2019-05-09 |
| JP5815652B2 (ja) | 2015-11-17 |
| JP2014057885A (ja) | 2014-04-03 |
| US8224414B2 (en) | 2012-07-17 |
| US20200362158A1 (en) | 2020-11-19 |
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